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Surekha M. Zingde, Ph.D.
Prof & former Deputy Director 
 
Advanced Centre for Treatment Research and Education in Cancer
Cancer Research Institute, Tata Memorial Centre, Kharghar
CH3-53, Kendriya Vihar, Sector 11, Kharghar
Navi Mumbai - 410 210   
Maharashtra   
 
E-mail: surekha.zingde@gmail.com
Phone: +91-22-27744595
Mobile: 9820633284
 
URL: http://actrec.gov.in/pi-webpages/SurekhaZingde/smz-index.htm
 
Positions Held:
Position Affiliation Time Period
Deputy Director,SO’H’ & PI Advanced Centre for Treatment, Research and Education in Cancer, Navi Mumbai, India 2007-2013
Deputy Director,SO’G’ & PI Advanced Centre for Treatment Research and Education in Cancer, Tata Memorial Centre 2006-Present
Head Biological Chemistry and Molecular Biology Div Advanced Centre for Treatment Research and Education in Cancer, Tata Memorial Centre 2002
Scientific Officer ‘F’ Cancer Research Institute, Tata Memorial Centre, Mumbai, India 1997-2001
Head Biological Chemistry and Molecular Biology Div Cancer Research Institute, Tata Memorial Centre, Mumbai, India 2001-2002
Head Molecular Biology Laboratory Cancer Research Institute, Tata Memorial Centre, Mumbai, India 1997-2000
Officer-in-Charge Cancer Research Institute, Tata Memorial Centre, Mumbai, India 1998-2000
Scientific Officer ‘SE’ Cancer Research Institute, Tata Memorial Centre, Mumbai, India 1994-1997
Officer-in-Charge Molecular Biology Laboratory Cancer Research Institute, Tata Memorial Centre, Mumbai, India 1994-1997
Scientific Officer ‘SE’ Cancer Research Institute, Tata Memorial Centre, Mumbai, India 1991-1994
Scientific Officer ‘SD’ BiologicalChemistry Division Cancer Research Institute, Tata Memorial Centre, Mumbai, India 1985-1991
Scientific Officer ‘SC’ Biological Chemistry Division Cancer Research Institute, Tata Memorial Centre, Mumbai, India 1979-1985
Visiting Fellow Molecular Biology Unit Tata Institute of Fundamental Research, Mumbai, India 1977-1979
Consultant
 
Area of Specialization:
Molecular Biology
Signaling mechanisms
Cancer Biology
Proteomics
Oral cancer
Research Summary:
Profiling of oral tumors by proteomics and immunoproteomics towards discovery of biomarkers and therapeutic targets
Biochemistry & Molecular Biology of granulocyte membrane proteins
Signal transduction in Granulocytes, Protein Kinase C in erythrocytes
 
Publications:
1. Sharma, S., Punjabi, V., Zingde, S. M. and Gokhale, S. M.  A Comparative Protein Profile of Mammalian Erythrocyte Membranes Identified by Mass Spectrometry. The Journal of Membrane Biology. 2014.  [PubMed]
2. Fulzele, A., Malgundkar, S. A., Govekar, R. B., Patil, A., Kane, S. V., Chaturvedi, P., D'Cruz, A. K. and Zingde, S. M.  Proteomic profile of keratins in cancer of the gingivo buccal complex: consolidating insights for clinical applications. Journal of Proteomics. 2013.  91, 242-258. [PubMed]
3. Sharma, S., Zingde, S. M. and Gokhale, S. M.  Identification of human erythrocyte cytosolic proteins associated with plasma membrane during thermal stress. The Journal of Membrane Biology. 2013.  246, 591-607. [PubMed]
4. Arjmand, F., Sayeed, F., Parveen, S., Tabassum, S., Juvekar, A. S. and Zingde, S. M.  Design and synthesis of (S)- and (R)-enantiomers of [4-(2-hydroxy-1-phenylethylimino)pent-2-ol]dimethyltin(iv) and 2,2-dimethyl-4-phenyl-1,3,2-oxazastannolidine: in vitro antitumor activity against human tumor cell lines and in vivo assay of (S)-enantiomers. Dalton Transactions. 2013.  42, 3390-3401. [PubMed]
5. Pranay, A., Shukla, S., Kannan, S., Malgundkar, S. A., Govekar, R. B., Patil, A., Kane, S. V., Chaturvedi, P., D'Cruz, A. K. and Zingde, S. M.  Prognostic utility of autoantibodies to alpha-enolase and Hsp70 for cancer of the gingivo-buccal complex using immunoproteomics. Proteomics. Clinical Applications. 2013.  7, 392-402. [PubMed]
6. Govekar, R. B., Kawle, P. D., Advani, S. H. and Zingde, S. M.  Reduced PKC alpha Activity Induces Senescent Phenotype in Erythrocytes. Anemia. 2012.  2012, 168050. [PubMed]
7. Fulzele, A., Malgundkar, S. A., Govekar, R. B., D'Cruz, A. K., Chaturvedi, P., Patil, A., Kane, S. V. and Zingde, S. M.  Keratins in oral cancer: necessity of mass spectrometry for validation of antibody based identifications. Journal of Proteomics. 2012.  75, 2404-2416. [PubMed]
8. Rukmini Govekar, Poonam Kawle, Renjan Thomas, Suresh H Advani, Sheena PV and Surekha M. Zingde: Eryptotic phenotype in chronic myeloid leukemia: contribution of neutrophilic cathepsin G. Anemia,2012  Volume 2012, Article ID 659303, 7 pages  doi:10.1155/2012/659303
9. Tabassum, S., Khan, R. A., Arjmand, F., Aziz, M., Juvekar, A. S. and Zingde, S. M.  Carbohydrate-conjugate heterobimetallic complexes: synthesis, DNA binding studies, artificial nuclease activity and in vitro cytotoxicity. Carbohydrate Research. 2011.  346, 2886-2895. [PubMed]
10. Kamal, A., Reddy, M. K., Ramaiah, M. J., Srikanth, Y. V., Reddy, V. S., Kumar, G. B., Pushpavalli, S. N., Bag, I., Juvekar, A., Sen, S., Zingde, S. M. and Pal-Bhadra, M.  Synthesis of aryl-substituted naphthalene-linked pyrrolobenzodiazepine conjugates as potential anticancer agents with apoptosis-inducing ability. ChemMedChem. 2011.  6, 1665-1679. [PubMed]
11. Tabassum S, Khan RA, Arjmand F, Sen S, Kayal J, Juvekar AS and Zingde SM. Synthesis and Characterization of Glycoconjugate Tin(IV) Complexes: in vitro DNA binding studies, cytotoxicity and cell death. J Organometallic Chemistry, 696: 8, 1600-1608, 2011  
12. Gadewal, N. S. and Zingde, S. M.  Database and interaction network of genes involved in oral cancer: Version II. Bioinformation. 2011.  6, 169-170. [PubMed]
13. Kamal A, Kumar BA, Suresh P, Juvekar A, Zingde S. Synthesis of 4 B-carbamoyl epipodophyllotoxins as potential antitumor agents. Biorganic Med Chem 2011, 19 (9) 2975-9.
14.
Kamal A, Vijaya Bharathi E, Janaki Ramaiah M, Surendranadha Reddy J, Dastagiri D, Viswanath A, Sultana F, Pushpavalli SN, Pal-Bhadra M, Juvekar A, Sen S, Zingde S.Synthesis, anticancer activity and apoptosis inducing ability of anthranilamide-PBD conjugates. Bioorg Med Chem Lett. 20(11):3310-3, 2010. 
15. Kamal A, Dastagiri D, Ramaiah MJ, Bharathi EV, Reddy JS, Balakishan G, Sarma;P, Pushpavalli SN, Pal-Bhadra M, Juvekar A, Sen S, Zingde S. Synthesis, anticancer activity and mitochondrial mediated apoptosis inducing ability of 2,5-diaryloxadiazole-pyrrolobenzodiazepine conjugates. Bioorg Med Chem. 2010 Sep 15;18(18):6666-77
16. Tabassum, S., Khan, R. A., Arjmand, F., Juvekar, A. S. and Zingde, S. M.  Synthesis of carbohydrate-conjugate heterobimetallic Cu(II)-Sn(2)(IV) and Zn(II)-Sn(2)(IV) complexes; their interactions with CT DNA and nucleotides; DNA cleavage, in-vitro cytotoxicity. European Journal of Medicinal Chemistry. 2010.  45, 4797-4806. [PubMed]
17. Kamal, A., Reddy, J. S., Ramaiah, M. J., Dastagiri, D., Bharathi, E. V., Azhar, M. A., Sultana, F., Pushpavalli, S. N., Pal-Bhadra, M., Juvekar, A., Sen, S. and Zingde, S.  Design, synthesis and biological evaluation of 3,5-diaryl-isoxazoline/isoxazole-pyrrolobenzodiazepine conjugates as potential anticancer agents. European Journal of Medicinal Chemistry. 2010.  45, 3924-3937. [PubMed]
18. Kamal A, Reddy KS, Khan MN, Shetti RV, Ramaiah MJ, Pushpavalli SN, Srinivas C, Pal-Bhadra M, Chourasia M, Sastry GN, Juvekar A, Zingde S, Barkume M. Synthesis, DNA-binding ability and anticancer activity of benzothiazole/benzoxazole-pyrrolo[2,1-c][1,4]benzodiazepine conjugates.  Bioorg Med Chem. 18(13), 4747-4761, 2010
19. Kamal, A., Bharati E. V., Ramaiah, M. J., Dastagiri, D., Reddy, J. S., Viswanath, A., Sultana, F., Pushpavalli, S.N., Pal-Bhadra, M., Srivastava, H.K., Sastry, N.G., Juvekar, A., Sen, S., Zingde, S. Quinazolinone linked pyrrolo[2,1-c][1,4]benzodiazepine(PBD conjugates: Design, synthesis and biological evaluation as anticancer agents. Bioorganic & Medicinal Chemistry. 2010. 18, 526-542.
20. Shukla, S., Pranay, A., D'Cruz, A. K., Chaturvedi, P., Kane, S. V. and Zingde, S. M.  Immunoproteomics reveals that cancer of the tongue and the gingivobuccal complex exhibit differential autoantibody response. Cancer Biomarkers. 2009.  5, 127-135. [PubMed]
21 Govekar R B., D’Cruz A K, Pathak_KA, Agarwal JP, Dinshaw K A, Chinoy RF, Gadewal N, Kannan S, Sirdeshmukh R, Sundaram CS, Malgundkar S A, Kane S V and Zingde S M. Proteomic profiling of cancer of the gingivo-buccal complex: Identification of new differentially expressed markers, Proteomics Clin. Appl. 2009, 3, 1451–1462. 
22. Kamal, A., Ramu, R., Tekumalla, V., Khanna, G. B., Barkume, M. S., Juvekar, A. S. and Zingde, S. M.  Remarkable DNA binding affinity and potential anticancer activity of pyrrolo[2,1-c][1,4]benzodiazepine-naphthalimide conjugates linked through piperazine side-armed alkane spacers. Bioorganic & Medicinal Chemistry. 2008.  16, 7218-7224. [PubMed]
23. Kamal A, Khan MN, Srikanth YV, Reddy KS, Juvekar A, Sen S, Kurian N and Zingde S: Synthesis, DNA-binding ability and evaluation of antitumour activity of triazolo[1,2,4]benzothiadiazine linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates. Bioorg. Med. Chem. 16(16): 7804-7810, 2008
24. Kamal, A., Kumar, P. P., Seshadri, B. N., Srinivas, O., Kumar, M. S., Sen, S., Kurian, N., Juvekar, A. S. and Zingde, S. M.  Phosphonate-linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates: synthesis, DNA-binding affinity and cytotoxicity. Bioorganic & Medicinal Chemistry. 2008.  16, 3895-3906. [PubMed]
25. Kamal, A., Shankaraiah, N., Devaiah, V., Laxma, R., Juvekar, A., Sen, S., Kurian, N. and Zingde, S.  Synthesis of 1,2,3-triazole-linked pyrrolobenzodiazepine conjugates employing 'click' chemistry: DNA-binding affinity and anticancer activity. Bioorganic & Medicinal Chemistry Letters. 2008.  18, 1468-1473. [PubMed]
26. Sawant, S. S., Zingde, S. M. and Vaidya, M. M.  Cytokeratin fragments in the serum: their utility for the management of oral cancer. Oral Oncology. 2008.  44, 722-732. [PubMed]
27. Kamal, A., Ramu, R., Tekumalla, V., Khanna, G.B., Barkume, M.S., Juvekar, A.S. and  Zingde, S.M. Synthesis, DNA-binding affinity and cytotoxicity studies of pyrrolo[2,1-c][1,4]benzodiazepine –anthroquinone conjugates, Bioorganic & Medicinal Chemistry. 2007. 15, 6868-6875.
28. Kamal, A., Khan, M.N., Reddy, K.S., Ahmed, S.K., Kumar, M.S., Juvekar, A., Sen, A. and Zingde, S. 1,2,4 Benzothiadazine linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates: Synthesis, DNA-binding affinity and cytotoxicity. Biorganic and Medicinal Chemistry letters. 2007. 17,5345-5348.
29. Shukla, S., Govekar, R. B., Sirdeshmukh, R., Sundaram, C. S., D'Cruz, A. K., Pathak, K. A., Kane, S. V. and Zingde, S. M.  Tumor antigens eliciting autoantibody response in cancer of gingivo-buccal complex. Proteomics - Clinical Applications. 2007.  1, 1592-1604. [PubMed]
30. Gadewal NS and Zingde SM: Data base and interactome map of oral cancer genes   Online journal of bioinformatics, 8 (1), 41-44, 2007
31. Govekar, R.B. and ZingdeS.M. Cancer proteomics: How far we are from the clinics? International Journal of Human Genetics. 2007. 7, 91-97.
32. Warawdekar, U. M., Zingde, S. M., Iyer, K. S., Jagannath, P., Mehta, A. R. and Mehta, N. G.  Elevated levels and fragmented nature of cellular fibronectin in the plasma of gastrointestinal and head and neck cancer patients. Clinica Chimica Acta. 2006.  372, 83-93. [PubMed]
33. West, C. M., McKay, M. J., Holscher, T., Baumann, M., Stratford, I. J., Bristow, R. G., Iwakawa, M., Imai, T., Zingde, S. M., Anscher, M. S., Bourhis, J., Begg, A. C., Haustermans, K., Bentzen, S. M. and Hendry, J. H.  Molecular markers predicting radiotherapy response: report and recommendations from an International Atomic Energy Agency technical meeting. International Journal of Radiation Oncology, Biology, Physics. 2005.  62, 1264-1273. [PubMed]
34. Balasubramanian, N., Advani, S. H. and Zingde, S. M.  Protein kinase C isoforms in normal and leukemic neutrophils: altered levels in leukemic neutrophils and changes during myeloid maturation in chronic myeloid leukemia. Leukemia Research. 2002.  26, 67-81. [PubMed]
35. Govekar, R. B. and Zingde, S. M.  Protein kinase C isoforms in human erythrocytes. Annals of Hematology. 2001.  80, 531-534. [PubMed]
36. Zingde, S. M. Cancer Genes. Current Science. 2001. 81, 508-514.
37. Zingde, S. M. The neutrophil in chronic myeloid leukemia: Molecular analysis of chemotaxis, endocytosis and adhesion. The Cancer Journal. 1998. 11, 167-175.
38. K. Saidas Nair and S. M. Zingde.  Adhesion of Neutrophils to Fibronectin : Role of the CD66 antigens. Cellular Immunology 208 : 96-106, 2001. 
39. Balasubramanian, N., Advani, S. H. and Zingde, S. M.  Protein kinase C isoforms in normal and chronic myeloid leukemic neutrophils. Distinct signal for PKC alpha by immunodetection on PVDF membrane, decreased expression of PKC alpha and increased expression of PKC delta in leukemic neutrophils. Leukemia Research. 1998.  22, 597-604. [PubMed]
40. Balasubramanian, N. and Zingde, S. M.  Even highly homologous proteins vary in their affinity for different blotting membranes. BioTechniques. 1997.  23, 390-392. [PubMed]
41. Kant, A. M., Advani, S. H. and Zingde, S. M.  Heterogeneity in the expression of Fc gammaRIII in morphologically mature granulocytes from patients with chronic myeloid leukemia. Leukemia Research. 1997.  21, 225-234. [PubMed]
42. Vijayan, K. V., Advani, S. H. and Zingde, S. M.  Chronic myeloid leukemic granulocytes exhibit reduced and altered binding to P-selectin: modification in the CD15 antigens and sialylation. Leukemia Research. 1997.  21, 59-65. [PubMed]
43. Kant, A. M., Advani, S. H. and Zingde, S. M.  Actin mRNA is not lowered in chronic myeloid leukemic granulocytes. Leukemia Research. 1996.  20, 739-741. [PubMed]
44. A.M.Kant, S. Advani and S. Zingde. FcRII and FcRIII on normal and leukemic granulocytes : A Flow cytometry and Northern Analysis. Leuk. Res. 20, #1, 93-99, 1996
45. A.M.Kant, S. Advani and S.Zingde. Decreased expression of both FcRII and FcIII mRNA in leukemic granulocytes. Leuk. Res. 19, #12, 997-1000, 1995.
46. Vijayan, V. K. and Zingde, S. M.  Heat-treated bovine serum albumin is a better blocking reagent for adhesion studies. BioTechniques. 1995.  18, 430-432. [PubMed]
47. Mehta, P., Zingde, S., Advani, S., Desai, H. and Gothoskar, B.  Protein 1a: a major wheat germ agglutinin binding protein on the surface of human granulocytes associated with the cytoskeleton. Molecular and Cellular Biochemistry. 1995.  144, 153-165. [PubMed]
48. Vijayan, V. K., Advani, S. H. and Zingde, S. M.  Chronic myeloid leukemic granulocytes exhibit decreased adhesion to fibronectin. Leukemia Research. 1994.  18, 877-879. [PubMed]
49. Batliwalla, F., Advani, S., Gothoskar, B. and Zingde, S.  Differential phosphorylation in normal and leukemic granulocytes in response to phorbol 12-myristate 13-acetate. Leukemia Research. 1994.  18, 327-336. [PubMed]
50. Karnik, M. P., Nair, C. N., Zingde, S. M., Gothoskar, B. P., Zachariah, L., Barbhaya, S. and Advani, S. H.  Use of polyclonal anti-myeloperoxidase antibody in myeloid lineage determination. The Indian Journal of Medical Research. 1994.  100, 272-276. [PubMed]
51. Desai, H., Zingde, S., Advani, S. and Gothoskar, B.  Differential phosphorylation--cause for defective internalization of aggregated IgG by chronic myeloid leukemic granulocytes? Leukemia Research. 1992.  16, 235-245. [PubMed]
52. Hingorani, R., Zingde, S. M., Tankkar, A., Advani, S. H. and Gothoskar, B. P.  A major concanavalin-A-binding cell surface protein from normal and leukemic granulocytes: isolation and characterization. Annals of Hematology. 1992.  65, 175-183. [PubMed]
53. Monteiro, J., Advani, S., Gothoskar, B. and Zingde, S. Decreased expression of FcRIII mRNA in leukemic granulocytes. FEBS Letters. 1992.300, 105-107.
54. Shirsat, N. V., Zingde, S. M., Advani, S. H. and Gothoskar, B. P.  The receptor for IgG on human normal and chronic myeloid leukemic granulocytes: functional and biochemical characterization. Cancer Biochemistry Biophysics. 1989.  10, 235-245. [PubMed]
55. Zingde, S. M., Advani, S. H. and Gothoskar, B. P.  Plasma membrane proteins from human normal and chronic myeloid leukemic granulocytes: identification and partial characterization of the concanavalin A-binding and detergent resistant proteins. Blut. 1987.  55, 89-100. [PubMed]
56. Zingde, S. M., Anklesaria, P. N., Advani, S. H., Bhisey, A. N. and Gothoskar, B. P.  Differential endocytosis of fluorescein iso-thiocyanate-concanavalin A by normal and chronic myeloid leukemic granulocytes. Blut. 1987.  55, 81-88. [PubMed]
57. Zingde, S. M., Shirsat, N. V. and Gothoskar, B. P.  Peptide mapping of proteins in gel bands after partial cleavage with acidic cyanogen bromide vapors. Analytical Biochemistry. 1986.  155, 10-13. [PubMed]
58. Zingde, S. M., Mungikar, A. M., Chhajlani, V., Advani, S. H. and Gothoskar, B. P.  Plasma membranes from normal and chronic myeloid leukemic granulocytes: isolation and two-dimensional polyacrylamide gel electrophoretic analysis. Cancer Biochemistry Biophysics. 1985.  7, 333-342. [PubMed]
59. Chhajlani, V., Zingde, S., Adwani, S. and Gothoskar, B.  Circulating immune complexes in chronic myeloid leukemia: turbidimetric measurement and two-dimensional electrophoretic analysis. Leukemia Research. 1983.  7, 565-573. [PubMed]
60. Mungikar, A. M., Zingde, S. M., Advani, S. H. and Gothoskar, B. P.  Mixed function oxidase enzymes in human normal granulocytes and chronic myeloid leukemia cells. I. Detection and estimation. Biochemical Medicine. 1983.  30, 181-187. [PubMed]
61. Zingde, S.M., Rodrigues, V., Joshi, S.M. and Krishnan, K.S. Molecular properties of Drosophila acetyl-cholinesterase. Journal of Neurochemistry. 1983. 41, 1243-1252.
62. Zingde, S. M. and Gothoskar, B. P.  Identification of a receptor for IgG on human granulocytes. FEBS Letters. 1982.  139, 317-320. [PubMed]
63. Laursen, R. A., L'Italien, J. J., Nagarkatti, S. and Miller, D. L.  The amino acid sequence of elongation factor Tu of Escherichia coli. The complete sequence. The Journal of Biological Chemistry. 1981.  256, 8102-8109. [PubMed]
64. T.R.Venkatesh, S.M.Zingde and K.S.Krishnan. Isolation and characterization of membranes from Drosophila melanogaster in Development and Neurobiology of Drosophila. Basic Life Science vol. 16 (Ed. O. Siddiqi, P.Babu, L.M.Hall and J.C.Hall). Plenum Press, New York, pp.313-321, 1980.
65. Arai, K., Clark, B. F., Duffy, L., Jones, M. D., Kaziro, Y., Laursen, R. A., L'Italien, J., Miller, D. L., Nagarkatti, S., Nakamura, S., Nielsen, K. M., Petersen, T. E., Takahashi, K. and Wade, M.  Primary structure of elongation factor Tu from Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 1980.  77, 1326-1330. [PubMed]
66. S.M.Zingde and K.S.Krishnan. The acetylcholinesterase from Drosophila melanogaster in Development and Neurobiology of Drosophila. Basic Life Sciences. 1980. Vol. 16 (Ed. O.Siddiqi, P.Babu,, L.M.Hall and J.C.Hall). Plenum Press, New York, pp.305-311.
67. D.L.Miller, S.Nagarkatti, R.A.Laursen, J.Parker and J.D.Friesen.  comparison of the activities of the products of the two genes for elongation factor Tu. Molecular & General Genetics : MGG. 1978.  159, 57-62. [PubMed]
68. Laursen, R. A., Nagarkatti, S. and Miller, D. L.  Amino acid sequence of elongation factor Tu. Characterization and alignment of the cyanogen bromide fragments and location of the cysteine residues. FEBS Letters. 1977.  80, 103-106. [PubMed]
69. Pedersen, S., Blumenthal, R. M., Reeh, S., Russell, L. B., Lemaux, P., Laursen, R. A., Nagarkatti, S. and Friesen, J. D.  A mutant of Escherichia coli with an altered elongation factor Tu. Proceedings of the National Academy of Sciences of the United States of America. 1976.  73, 1698-1701. [PubMed]

 
Book Chapters:
S.M.Zingde, R.Hingorani, J.Monteiro, A.Tankkar and B.P.Gothoskar. A major human granulocyte surface glycoprotein - Isolation and cloning in Biotechnology - Human Welfare. Ed. P.P.Reddy and A.Jyothy. Institute of Genetics, Hyderabad, pp.55-59, 1991.
K.V.Vijayan and S.Zingde, Adhesion of cells to fibronectin. (Ed. M.G.Deo, R.Seshadri, R.Mulherkar, R.Mukhopadhaya, A.N.Bhisey).National Institute of Science Communication, New Delhi, pp49-51, 1997.
S.M.Zingde. Cell and macromolecule separation. (Ed. M.G.Deo, R.Seshadri, R.Mulherkar, R.Mukhopadhaya, A.N.Bhisey).National Institute of Science Communication, New Delhi, pp 70-71, 1997.
A.Kant and S.Zingde, Nuclear run off analysis. (Ed. M.G.Deo, R.Seshadri, R.Mulherkar, R.Mukhopadhaya, A.N.Bhisey).National Institute of Science Communication, New Delhi, p142-145, 1997.
S.Zingde. Large scale preparation of plasmids. (Ed. M.G.Deo, R.Seshadri, R.Mulherkar, R.Mukhopadhaya, A.N.Bhisey).National Institute of Science Communication, New Delhi, p170-172, 1997.
S.Zingde, Cloning in M13 for nucleotide sequencing. (Ed. M.G.Deo, R.Seshadri, R.Mulherkar, R.Mukhopadhaya, A.N.Bhisey).National Institute of Science Communication, New Delhi, p175-179, 1997.
 
Grant Support:
Project Title Role Funding Agency Sanction Number Sanction Date
Screening of anticancer drugs from the sea Principal Investigator Ministry of Earth Sciences, India MoES/9-DS/6/2007-PC IV 2007-2012
Post translational modifications of Cytokeratin 8 and 18: Potential biomarkers for cancer of buccal mucosa Principal Investigator Lady Tata Memorial Trust, India 2008-2011
Curcumin clinical trials in cancer Co-Investigator Department of Biotechnology, Government of India 102/IFD/SAN-1291/2009-2010 2009-2014
Design of novel anticancer drugs and analysis of their therapeutic potential by in vitro and invivo studies Co-Investigator Department of Biotechnology, Government of India BT/PR 6345/Med/14/784/2005, dated 26/2/2007 2007-2010
Design, synthesis and biological evaluation of new hybrids based on Pyrrolo[2,1- c][1,4] benzodiazepines Co-Investigator Department of Biotechnology, Government of India BT/PR/7037/MED/14/933/2006 dated 28.03.2006 2006-2009
To confirm the role of Protein kinase C delta in aggregation of Band 3 in CML erythrocytes Co-Investigator Lady Tata Memorial Trust, India 2006-2009
An in vivo study to evaluate the role of curcumins in oral premalignant lesions and gingivo-buccal cancers Co-Investigator Department of Biotechnology, Government of India 2007-2009
Study of tumor antigens which elicit humoral immune response in oral cancer Principal Investigator Council of Scientific and Industrial Research, Government of India 27(0151)/06/EMRII 2007-2010
New targets and markers for cancer using genomics and proteomics Principal Investigator Council of Scientific and Industrial Research, Government of India CSIR-NMITLI, 5/258/3/2000-NMITLI 2001-2006
Adhesion of normal and leukemic granulocytes to Fibronectin Principal Investigator Lady Tata Memorial Trust, India 1995-2000
Studies on Protein Kinase C isoforms in normal and leukemic granulocytes Principal Investigator Council of Scientific and Industrial Research, Government of India 27/58/95-EMR-II 1995-1999
The major concanavalin A binding membrane protein from normal and leukemic granulocytes : Expression in relation to maturity Principal Investigator Department of Science & Technology, Government of India SP/SO/D81/89 1990-1994
Plasma membrane proteins from normal and leukemic granulocytes: Isolation, biochemical characterization and gene cloning Principal Investigator Department of Science & Technology, Government of India SP/SO/D64/86 1987-1990

 
 
My CV:   Download
 
Education 
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M.Sc. in Chemistry, Indian Institute of Technology, Bombay, India
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Ph.D. in Chemistry, Boston University, Boston, USA, 1972-1977
Honors and Awards
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President, Proteomics Society, India
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Fellow of the Maharashtra Academy of Sciences and the Sigma Xi, USA
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Institute Silver Medal for securing the first position in the M.Sc. program of the Indian Institute of Technology, Powai, Mumbai 1972
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Dr R Kinjariwal Oration Award 2009 by the Gujarat Cancer and Research Institute, Ahmedabad
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The UICC International Cancer Fellowship ICRETT to work on “Endothelial cell culture and gene transfer into mammalian cells” in the laboratory of Dr.T.V.Gopal of Clonexpress Inc. Gaithersburg, U.S.A.
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Asian Molecular Biology Organization (Japan) scholarship to attend the course on non-radioisotopic methods for analyzing DNA and RNA, held at Jikei University School of Medicine, Tokyo, Japan, during 4th-9th Feb. 1985
Member
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Member of committees of CSIR, Department of Biotechnology, Lady Tata Memorial Trust and Board of Research in Nuclear Sciences of the Department of Atomic Energy
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Domain Expert Group Member for the Monitoring committee of the CSIR for the project on Discovery and validation of new biomarkers for head & neck cancer in Indian population: July 2010 onwards to date
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Member of Executive Committee of the Indian Womens Scientists Association, Vashi, Navi Mumbai April 2013-March 2015
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Past Member of the Research & Recognition Committee in Biochemistry of the University of Mumbai (2000-2005) and Board of Studies in Life Sciences of the Homi Bhabha National Institute (2005-2013)
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Past Vice President of the Indian Association of Cancer Research (2003-2005)
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Past Member of the executive committee of the Indian Society of Cell Biology (1999-2001)
Type of Neoplasms
 
Head and Neck
Oral cavity
  Last modified on : Dec 9, 2015
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.