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Milind M. Vaidya, Ph.D.
Scientific Officer 
Advanced Centre for Treatment Research and Education in Cancer
Khanolkar Shodhika, Tata Memorial Centre, Kharghar
Navi Mumbai - 410 210   
Phone: +91-22-27405055
Fax: +91-22-27405085
Area of Specialization:
Research Summary:
Use of cytokeratins as prognostic markers in human oral precancer and cancer
Studies on possible role of cytokeratin 8 and 18 in malignant transformation of stratified epithelial cells and fibroblast and interactions of cytokeratins and vimentin with intermediate filament associated proteins
Establishment and characterization of cell lines derived from genetically transformed FBM cells
Studies on changes in cytokeratin expression, filament formation and interactions of cytokeratins with desmosomal and hemidesmosomal proteins in oral carcinogenesis using rat oral mucosa
Analysis of CK serum markers in early detection of recurrent/ metastatic disease and their prognostic value in oral squamous cell carcinoma
Cytokeratin mediated regulation of apoptosis signaling in stratified epithelia and its role in acquisition of transformed phenotype
Global profiling of proteins in experimental rat buccal mucosal and lingual carcinogenesis: a sequential study
1. Sawant, S. S., Chaukar, D. A., Joshi, S. S., Dange, P. P., Kannan, S., Kane, S., D'Cruz, A. K. and Vaidya, M. M.  Prognostic value of tissue polypeptide antigen in oral squamous cell carcinoma. Oral Oncology. 2010.  [PubMed]
2. Srikanth, B., Vaidya, M. M. and Kalraiya, R. D.  O-GlcNAcylation determines the solubility, filament organization, and stability of keratins 8 and 18. The Journal of Biological Chemistry. 2010.  285, 34062-34071. [PubMed]
3. Sawant, S. S., Zingde, S. M. and Vaidya, M. M.  Cytokeratin fragments in the serum: their utility for the management of oral cancer. Oral Oncology. 2008.  44, 722-732. [PubMed]
4. Vaidya, M. M. and Kanojia, D.  Keratins: markers of cell differentiation or regulators of cell differentiation? Journal of Biosciences. 2007.  32, 629-634. [PubMed]
5. Kanojia, D. and Vaidya, M. M.  4-nitroquinoline-1-oxide induced experimental oral carcinogenesis. Oral Oncology. 2006.  42, 655-667. [PubMed]
6. Ranganathan, K., Kavitha, R., Sawant, S., S. and Vaidya, M., Cytokeratin expression in oral submucous fibrosis – an Immunohistochemical study.Journal of Oral Pathology & Medicine ; 2006, 35(1), 25-32.
7. Raul, U., Sawant, S., Dange, P., Kalraiya, R., Ingle, A. and Vaidya, M.  Implications of cytokeratin 8/18 filament formation in stratified epithelial cells: induction of transformed phenotype. International Journal of Cancer.  2004.  111, 662-668. [PubMed]
8. Upasani, O. S., Vaidya, M. M. and Bhisey, A. N.  Database on monoclonal antibodies to cytokeratins. Oral Oncology. 2004.  40, 236-256. [PubMed]
9. Sawant, S., S., Naresh, K., N., D’Cruz, A., Ogale, S., B. and Vaidya, M., M., Demonstration of cytokeratin-5 non-expression in tobacco related oral carcinogenesis-use of reverse transcriptase polymerase chain reaction as a sensitive assay. Oral Oncology; 2003, 39:789-795.
10. Vaidya, M., M., Sawant, S., S., Borges, A., M., Naresh, N., K., Purandare, M., C. and Bhisey, A., N. Cytokeratin expression in human fetal tongue and buccal mucosa. Journal of Biosciences; 2000, 25: 235-242.
11. Vaidya, M., M., Sawant, S., S., Borges, A., M., Ogale, S., B. and Bhisey, A., N., Cytokeratin expression in precancerous lesions of the human oral cavity. Oral Oncol Europian Journal of Cancer; 1998, 34(4):261-264.
12. Vaidya M.M., Borges A.M., Pradhan S.A. and Bhisey A.N. Cytokeratin expression in squamous cell carcinomas of the tongue and alveolar mucosa. Oral Oncology Europian Journal of  Cancer. 1996. 32. 333-336.
13. Bhisey, A., N., Vaidya, M., M., Borges, A., M. and Pradhan, S., A., Cytokeratin expression in human oral squamous cell carcinomas. Oral Cancer.Tata Memorial Centre, Goldren Jubilee Publication 1991,228-235 .
14. Vaidya M.M., Borges A.M., Pradhan S.A., Rajpal R.M. and Bhisey A.N. Altered keratin expression in buccal mucosal squamous cell carcinoma. Journal of Oral Pathology and Medicine. 1989. 18. 282-286.


Book Chapters:
Bhisey, A.N., Vaidya, M.M., Borges, A.M. and Pradhan, S.A. Cytokeratin expression in human oral squamous cell carcinomas In: Oral Cancer. Rao, R.S. and Desai, P.B. Tata Memorial Centre, Golden Jubilee Publication. 1991. pp 228-235.
  Last modified on : Mar 4, 2011
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