INCREDB ID : 81
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Mausumi Bharadwaj, Ph.D.
Scientist D 
 
Institute of Cytology and Preventive Oncology
Division of Molecular Genetics and Biochemistry
I-7, sector-39
Noida - 201 301   
Uttar Pradesh   
 
E-mail: bharadwajm@icmr.org.in, mausumib@hotmail.com
Phone: +91-120-2579471
Fax: +91-120-2579473
 
URL: http://icmr.nic.in/icmrsql/biodata.asp?expno=00011688
 
Positions Held:
Position Affiliation Time Period
Chief & Assistant Director Centre for Biochemical Technology, Delhi University Camp, Delhi, India 2003-Present
Senior Scientist Institute of Genomics and Integrative Biology, New Delhi, India 2001-2003
Assistant Professor University of New Mexico, School of Medicine, Albuquerque, USA 1999-2000
Research Associate Staff I University of New Mexico, School of Medicine, Albuquerque, USA 1995-1999
Research Associate Staff I University of New Mexico, School of Medicine, Albuquerque, USA 1993-1995
Post Doctoral Fellow University of Health Sciences, The Chicago Medical School, Chicago, USA 1992-1993
 
Area of Specialization:
Molecular Oncology
Research Summary:
Human Papillomavirus investigations
Polymorphism in Cervical Cancer
DNA Vaccines
 
Publications:
1. Hussain, S., M, Y., Thakur, N., Salam, I., Singh, N., Mir, M. M., Bhat, M. A., Siddiqi, M. A., Das, B. C. and Bharadwaj, M.  Association of cyclin D1 gene polymorphisms with risk of esophageal squamous cell carcinoma in Kashmir Valley-A high risk area. Molecular Carcinogenesis. 2011.  [PubMed]
2. Sobti, R. C., Singh, N., Hussain, S., Suri, V., Bharadwaj, M. and Das, B. C.  Deregulation of STAT-5 isoforms in the development of HPV-mediated cervical carcinogenesis. Journal of Receptor and Signal Transduction Research. 2010.  30, 178-188. [PubMed]
3. Bharadwaj, M., Hussain, S., Nasare, V. and Das, B. C.  HPV & HPV vaccination: issues in developing countries. The Indian Journal of Medical Research. 2009.  130, 327-333. [PubMed]
4. Das, B. C., Bharti, A. C. and Bharadwaj, M.  Human papillomavirus & cervical cancer: looking ahead. The Indian Journal of Medical Research. 2009.  130, 210-211. [PubMed]
5. Neyaz, M. K., Hussain, S., Hassan, M. I., Das, B. C., Husain, S. A. and Bharadwaj, M.  Novel missense mutation in FHIT gene: interpreting the effect in HPV-mediated cervical cancer in Indian women. Molecular and Cellular Biochemistry. 2010.  335, 53-58. [PubMed]
6. Thakur, N., Hussain, S., Kohaar, I., Tabassum, R., Nasare, V., Tiwari, P., Batra, S., Bhambhani, S., Das, B. C., Basir, S. F., Bharadwaj, D. and Bharadwaj, M.  Genetic variant of CCND1: association with HPV-mediated cervical cancer in Indian population. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility To Chemicals. 2009.  14, 219-225. [PubMed]
7. Singhal, S., Kohaar, I., Bharadwaj, M., Shukla, D. K., Das, B. C. and Kar, P.  Association of tumor necrosis factor-alpha gene promoter polymorphisms with acute viral hepatitis in the Indian population. Digestive Diseases and Sciences. 2010.  55, 1106-1112. [PubMed]
8. Mahajan, A., Tabassum, R., Chavali, S., Dwivedi, O. P., Bharadwaj, M., Tandon, N. and Bharadwaj, D.  High-sensitivity C-reactive protein levels and type 2 diabetes in urban North Indians. The Journal of Clinical Endocrinology and Metabolism. 2009.  94, 2123-2127. [PubMed]
9. Kohaar, I., Hussain, S., Thakur, N., Tiwari, P., Nasare, V., Batra, S., Bizzozero, O.A., Sabine, U., Tetzloff and Bharadwaj, M.      Protein palmitoylation in the nervous system: current views and unsolved problems. Neurochemical Research. 1994. 19, 923-933.Singh, V., Bhambani, S., Das, B. C., Sarkar, D. P. and Bharadwaj, M.  Association between human leukocyte antigen class II alleles and human papillomavirus-mediated cervical cancer in Indian women. Human Immunology. 2009.  70, 222-229. [PubMed]
10. Neyaz, M. K., Kumar, R. S., Hussain, S., Naqvi, S. H., Kohaar, I., Thakur, N., Kashyap, V., Das, B. C., Husain, S. A. and Bharadwaj, M.  Effect of aberrant promoter methylation of FHIT and RASSF1A genes on susceptibility to cervical cancer in a North Indian population. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility To Chemicals. 2008.  13, 597-606. [PubMed]
11. Das, B. C., Hussain, S., Nasare, V. and Bharadwaj, M.  Prospects and prejudices of human papillomavirus vaccines in India. Vaccine. 2008.  26, 2669-2679. [PubMed]
12. Kohaar, I., Tiwari, P., Kumar, R., Nasare, V., Thakur, N., Das, B. C. and Bharadwaj, M.  Association of single nucleotide polymorphisms (SNPs) in TNF-LTA locus with breast cancer risk in Indian population. Breast Cancer Research and Treatment. 2009.  114, 347-355. [PubMed]
13. Kohaar, I., Thakur, N., Salhan, S., Batra, S., Singh, V., Sharma, A., Sodhani, P., Das, B. C., Sarkar, D. P. and Bharadwaj, M.  TNFalpha-308G/A polymorphism as a risk factor for HPV associated cervical cancer in Indian population. Cellular Oncology : the Official Journal of the International Society For Cellular Oncology. 2007.  29, 249-256. [PubMed]
14. Bharadwaj, M., Mirowsky, K., Ye, C., Botten, J., Masten, B., Yee, J., Lyons, C. R. and Hjelle, B.  Genetic vaccines protect against Sin Nombre hantavirus challenge in the deer mouse (Peromyscus maniculatus). The Journal of General Virology. 2002.  83, 1745-1751. [PubMed]
15. Kohaar, I., Thakur, N., Salhan, S., Batra, S., Singh, V., Sharma, A., Sodhani, P., Das, B. C., Sarkar, D. P. and Bharadwaj, M. TNF–308G/A polymorphism as a risk factor for HPV associated Cervical Cancer in Indian population. Cellular Oncology. 2007 (In press).
16. Singhal, S., Kohaar, I., Bharadwaj, M., Chakravarty, A., Gondal, R., Das, B.C. and Kar, P.. Fas and TNF mediated apoptosis and TNF gene polymorphism in fulminant hepatic failure and its clinical relevance. American Journal of Gastroenterology. 2006. 101, 322.
17. Thakur, N., Kohar, I., Batra, S., Singh, V., Gupta, S., Das, B.C. and Bharadwaj, M. Involvement of molecular marker in cervical cancer.  Indian Journal of Medical Research. 2005. 121 (Supplement), 110.
18. Kohaar, I., Thakur, N., Salhan, S., Sodhani, P., Mahendra, P., Mishra, A., Das, B.C., Sarkar, D.P. and Bahradwaj, M. Polymorphism of Cytokine Gene, Tumor Necrosis Factor in Cervical Cancer. Indian Journal of Medical Research. 2005, 121 (Supplement), 106.
19. Bharadwaj, M., Nofchissey, R., Goade, D., Koster, F. and Hjelle, B. Humoral immune responses in the hantavirus cardio-pulmonary syndrome. Journal of Infectious Diseases.2000. 182, 43-48.
20. Botten, J., Mirowsky, K., Kusewitt, D., Bharadwaj, M., Feddersen, R., Ricci, R. and Hjelle, B. Animal model for Sin Nombre Hantavirus infection in the deer mice (Peromyscus maniculatus) using a novel outdoor biocontainment facility: early viral invasion of heart and brown fat. Proc. Natl. Acad. Sci. USA. 2000. 97, 10578-10583.
21. Pai, R.K., Bharadwaj, M., Levy, H., Overturf, G., Goade, D.,  Wortman, I.A., Nofchissey, R. and Hjelle, B. Absence of Infection of a Neonate after Probable Exposure to Sin Nombre Hantavirus in breast milk. Clinical Infectious Diseases. 1999. 29, 1577-1579.
22. Bharadwaj, M., Lyons, C.R., Wortman, B. and Hjelle, B. Intramuscular inoculation of Sin Nombre virus cDNAs induces cellular and humoral immune responses in BALB/c mice. Vaccine. 1999, 17, 2836-2843.
23. Hjelle, B., Martinez, N.R. and Bharadwaj, M. Recombinant western blot and strip immunoblot assays for hantaviruses. Manual of Hemorrhagic Fever with Renal Syndrome and Hantavirus Syndrome. 1999. 122-130.
24. Martinez, N.T., Bharadwaj, M., Goade, D., Delury, J.,  
Moran, P., Hicks, B., Nix, B., James, L., Davis, Hjelle, B. Bayou virus associated hantavirus pulmonary syndrome in eastern Texas: Identification of the rice rat Oryzomys palustris as the reservoir host. Emerging Infectious Dis. 1998. 4, 105-111.
25. Ferrer, J.F., Johnson, C., Esteban, E., Galligan, D., Basombrio, M.A., Ramos, M.P., Bharadwaj, M., Martinez, N.R., Callahan, J., Segovia, A., Hjelle, B. High prevalence of hantavirus infection in Indian communities of the Paraguayan and Argentinean Gran Chaco. Amer. J. Trop. Med. Hyg. 1998, 59, 438-444.
26. Bharadwaj, M., Botten, J., Martinez, M.R. and Hjelle, B. Rio Mamore hantavirus: genetic characteristics of a newly-recognized virus of the pygmy rice rat, Oligoryzomys microtis, from Bolivia.  Amer. J. Trop. Med. Hyg. 1997. 57, 368-374.
27.   Julie, A., Rawlings., Martinez, N.R., Susan, U., Neil, Moore, M.G., Hicks, B.N., Pichuantes, S., Nguyen, A., Bharadwaj, M. and Hjelle, B.  Cocirculation of multiple hantaviruses in Texas, with characterization of the S genome of a previously-undesBharadwaj, M. and Bizzozero, O.A. Myelin Po glycoprotein
and the synthetic peptide IRYCWLRR are both autoacylated. J. Neurochemistry.1995. 65, 1805-1815.cribed virus of cotton rats (Sigmodon hispidus).  Amer. J. Trop. Med. Hyg. 1996. 55, 672-679.
28. Bharadwaj, M., Bharadwaj, D. and Hati, R.N. Characterization of a membrane protease from rat submaxillary gland
 mitochondria that possess thrombin-like activity.  Biochem. J. 1996. 313,193-199.
29. Bharadwaj, M. and Bizzozero, O.A. Myelin Po glycoprotein
and the synthetic peptide IRYCWLRR are both autoacylated. J. Neurochemistry. 1995. 65, 1805-1815.
30. Bizzozero, O.A., Sabine, U., Tetzloff and Bharadwaj, M.      Protein palmitoylation in the nervous system: current views and unsolved problems. Neurochemical Research. 1994. 19, 923-933.
31. Bharadwaj, D., Roy, M.S., Bose, D. and Hati, R.N. A new blood coagulating protease in mitochondrial membranes  of rat submaxillary gland.  Purification and characterization of protease and its blood coagulating activity. J. Biol. Chem. 1994. 269, 16229-16235.
32. Bharadwaj, D., Mukherjee, A., Roy, M.S., Hati, R.N. and Mukherjee, R.N. Silanized silica bound trypsin as analytical probe.  Indian J. Biochem. Biophys. 1992. 29, 375-377.
33. Roy, M.S., Bharadwaj, D. and Hati. R.N. Chymotrypsinogen: an activating enzyme in mitochondrial membrane of rat submaxillary gland. Biochemistry International. 1991. 25, 1035-1041.
34. Roy, M.S.,  Bharadwaj, D. and Hati, R.N. Resolution of peripheral membrane proteases from mitochondrial pellet of rat submaxillary gland. Current Science. 60, 325-326.

 
Grant Support:
Project Title Role Funding Agency Sanction Number Sanction Date
Development of prophylactic DNA-based vaccine against human papillomavirus type 16 and 18 Principal Investigator
Polymorphism of cytokine gene tumor necrosis factor alpha (TNF alpha) in cervical cancer Principal Investigator
Cyclin D1 gene polymorphism in cervical precancer and cancer Principal Investigator
Single nucleotide polymorphisms of cytokine genes in human papillomavirus (HPV)- mediated cervical cancer in women Principal Investigator Council of Scientific and Industrial Research, Government of India
Role of tobacco use in causation of cancer in North East India. ICMR Task Force project Co-Investigator Indian Council of Medical Research
Role of pesticide exposure in causation of cancer in North East India Co-Investigator Indian Council of Medical Research
Prevalence and persistence of HPV infection during and after pregnancy and its transmission to child Co-Investigator
Prevalence of HPV infection and MTHFR gene polymorphism in peri and post menopausal women Co-Investigator

 
 
My CV:   Download
 
Education 
::
M.Sc. in Biochemistry, University of Calcutta, Kolkata, India
::
Ph.D. Jadavpur University, Kolkata, India
Honors and Awards
::
1996, Travel award from the 45th Annual Meeting of the American Society of Tropical Medicine and Hygiene held in Baltimore, Maryland
Member
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The American Society of Tropical Medicine and Hygiene
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The American Society of Virology
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Indian Association for Cancer Research
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Society of Biological Chemists
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Ad hoc Reviewer of the journal, Indian Journal of Biochemistry and Biophysics
Type of Neoplasms
Female genital system
Cervix
  Last modified on : Mar 4, 2011
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.