Ramkumar Hariharan, Ph.D.
Scientist B
Rajiv Gandhi Centre for Biotechnology
Thycaud, Poojappura
Thiruvananthapuram - 695 014
Kerala
E-mail: rmhariharan@rgcb.res.in
Phone: +91-471-2529488
URL: http://rgcb.res.in/departments/cancer_research/ramkumar-hariharan/profile.html
Positions Held:
Position
Affiliation
Time Period
Scientist B
Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, India
2008-Present
Visiting Scientist
RIKEN Advanced Science Institute, Yokohama, Japan
Area of Specialization:
Bioinformatics
Research Summary:
Computational genomics and systems biology
Publications:
1.
Sreekumar, E., Issac, A., Nair, S., Hariharan, R ., Janki, M. B., Arathy, D. S., Regu, R., Mathew, T., Anoop, M., Niyas, K. P. and Pillai, M. R. Genetic characterization of 2006-2008 isolates of Chikungunya virus from Kerala, South India, by whole genome sequence analysis. Virus Genes. 2010. 40, 14-27. [PubMed]
2.
Hariharan, R. , Babu, J. M., P, R. and Pillai, M. R. Mutational analysis of Smad7 in human cervical cancer. Oncology Reports. 2009. 21, 1001-1004. [PubMed]
3.
Krishnan, A., Hariharan, R ., Nair, S. A. and Pillai, M. R. Fluoxetine mediates G0/G1 arrest by inducing functional inhibition of cyclin dependent kinase subunit (CKS)1. Biochemical Pharmacology. 2008. 75, 1924-1934. [PubMed]
4.
Hariharan, R . and Pillai, M. R. Structure-function relationship of inhibitory Smads: Structural flexibility contributes to functional divergence. Proteins. 2008. 71, 1853-1862. [PubMed]
5.
Joy, S., Nair, P. S., Hariharan, R . and Pillai, M. R. Detailed comparison of the protein-ligand docking efficiencies of GOLD, a commercial package and ArgusLab, a licensable freeware. In Silico Biology. 2006. 6, 601-605. [PubMed]
6.
Ramachandran, S., Ramadas, K., Hariharan, R ., Rejnish, K. and Radhakrishna, P. Single nucleotide polymorphisms of DNA repair genes XRCC1 and XPD and its molecular mapping in Indian oral cancer. Oral Oncology. 2006. 42, 350-362. [PubMed]
7.
Hariharan, R . and Pillai, M. R. Homology modeling of the DNA-binding domain of human Smad5: a molecular model for inhibitor design. Journal of Molecular Graphics & Modelling. 2006. 24, 271-277. [PubMed]
8.
Pillai, M. R., Hariharan, R. , Babu, J. M., Lakshmi, S., Chiplunkar, S. V., Patkar, M., Tongaonkar, H., Dinshaw, K., Jayshree, R. S., Reddy, B. K., Siddiqui, M., Roychoudury, S., Saha, B., Abraham, P., Gnanamony, M., Peedicayil, A., Subhashini, J., Ram, T. S., Dey, B., Sharma, C., Jain, S. K. and Singh, N. Molecular variants of HPV-16 associated with cervical cancer in Indian population. International Journal of Cancer. Journal International Du Cancer. 2009. 125, 91-103. [PubMed]
Grant Support:
Project Title
Role
Funding Agency
Sanction Number
Sanction Date
Studying the role of microRNAs in etiologically diverse oral carcinomas
Department of Science & Technology, Government of India
2009-2012
To develop vaccines against Classical Swine Fever and delivery through conjugated nanoparticles
Co-Investigator
Department of Biotechnology, Government of India
2008-2014
Education
::
M.Sc. in Biotechnology,
University of Kerala
::
Ph.D. in Biotechnology,
University of Kerala
Honors and Awards
::
Researcher Exchange Program award by the British Council to undertake collaborative work with Oxford University, UK
::
Visiting Scientist to RIKEN Advanced Science Institute, Yokohama, Japan