S. Sreeja, Ph.D.
Scientist C
Rajiv Gandhi Centre for Biotechnology
Thycaud, Poojappura
Thiruvananthapuram - 695 014
Kerala
E-mail: ssreeja@rgcb.res.in
Phone: +91-471-2529474
URL: http://rgcb.res.in/departments/cancer_research/s-sreeja/profile.html
Positions Held:
Position
Affiliation
Time Period
Scientist C
Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, India
2005-Present
Scientist B
Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, India
2001-2005
Research Officer
Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, India
1993-2001
Research Assistant
Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, India
1992-1993
Area of Specialization:
Biotechnology
Research Summary:
Differential gene expression in breast tumor tissue at different stages of menstrual cycle
Screening of dietary estrogens for its selective estrogen receptor modulatory (SERM) activity
Publications:
1.
Sreeja, S. , Anju, V. S. and Sreeja, S. In vitro estrogenic activities of fenugreek Trigonella foenum graecum seeds. The Indian Journal of Medical Research. 2010. 131, 814-819. [PubMed]
2.
Sreeja, S . and Sreeja, S. An in vitro study on antiproliferative and antiestrogenic effects of Boerhaavia diffusa L. extracts. Journal of Ethnopharmacology. 2009. 126, 221-225. [PubMed]
3.
Jacob, J., Sebastian, K. S., Devassy, S., Priyadarsini, L., Farook, M. F., Shameem, A., Mathew, D., Sreeja, S . and Thampan, R. V. Membrane estrogen receptors: genomic actions and post transcriptional regulation. Molecular and Cellular Endocrinology. 2006. 246, 34-41. [PubMed]
4.
Sreeja, S . and Thampan, R. Functional roles of plasma membrane localized estrogen receptors. Indian Journal of Experimental Biology. 2003. 41, 740-747. [PubMed]
5.
Sebastian, T., Sreeja, S . and Thampan, R. V. Import and export of nuclear proteins: focus on the nucleocytoplasmic movements of two different species of mammalian estrogen receptor. Molecular and Cellular Biochemistry. 2004. 260, 91-102. [PubMed]
6.
Sreeja, S . and Thampan, R. V. Proteins which mediate the nuclear entry of goat uterine non activated estrogen receptor (naER) following naER internalization from the plasma membrane. Molecular and Cellular Biochemistry. 2004. 259, 141-148. [PubMed]
7.
Sreeja, S . and Thampan, R. V. Estradiol-mediated internalisation of the non-activated estrogen receptor from the goat uterine plasma membrane: identification of the proteins involved. Molecular and Cellular Biochemistry. 2004. 259, 131-140. [PubMed]
8.
Govind, A. P., Sreeja, S . and Thampan, R. V. Proteins that mediate the nuclear entry of the goat uterine estrogen receptor activation factor (E-RAF): identification of a molecular basis for the inhibitory effect of progesterone on estrogen action. Journal of Cellular Biochemistry. 2003. 89, 108-119. [PubMed]
9.
Govind, A. P., Sreeja, S. and Thampan, R. V. Estradiol dependent anchoring of the goat uterine estrogen receptor activation factor (E-RAF) at the endoplasmic reticulum by a 55 kDa anchor protein (ap55). Journal of Cellular Biochemistry. 2003. 89, 94-107. [PubMed]
10.
Thampan, R. V., Zafar, A., Imam, N. S., Sreeja, S ., Suma, K. and Vairamani, M. Cholesterol inhibits the nuclear entry of estrogen receptor activation factor (E-RAF) and its dimerization with the nonactivated estrogen receptor (naER) in goat uterus. Journal of Cellular Biochemistry. 2000. 77, 382-395. [PubMed]
11.
Aneef J and S.Sreeja . Phytoestrogens: An overview. The Icfai University journal of Biotechnology .2009. 3, 48-60.
Education
::
Ph.D. in Biotechnology,
University of Kerala
Member
::
SBTI