Tanuja R. Teni,                               Ph.D. 
                               
                              Assistant Professor  
                           
                         
                                  
         
                                                    
                                                    
                            Advanced Centre for Treatment Research and Education in Cancer 
                           
                                                                              
                            Teni Lab 
                           
                                                                              
                            Tata Memorial Centre, Kharghar 
                           
                                                    
                            Navi Mumbai - 410 210.                                 
                           
                                                    
                            Maharashtra                                 
                           						  
                                                            
                           
                                                    
                            E-mail: tteni@actrec.gov.in 
                           
                                                                              
                            Phone: +91-22-27405071 
                           
                                                    
                            Fax: +91-22-27405085  
                           
                  
                          
                               
                           
                          
                            URL:   http://actrec.gov.in/pi-webpages/TanujaTeni/tanuja-index.htm  
                           
                          
                          						  
                              
                           
						  
	                                                       
                            Area of Specialization:  
                           
                          
                          
  
     
    Molecular Biology 
   
     
                          
                        
                           
                           
                         
                         
                                                    
                                                    
                          
                             
                           
                                                    
                             Research Summary:  
                           
                                                    
                            
                                                                
                                   
                                  Molecular analysis of apoptosis signaling pathways in oral cancer 
                                 
                                                                
                                   
                                  Molecular basis of oral submucous fibrosis and leukoplakias 
                                 
                                                                
                                   
                                  Recurrence and radiation response-associated genes in oral and cervical cancers – biomarkers and therapeutic targets 
                                 
                                                                
                                   
                                  Regulation of NF-kappaB signaling pathway in HPV-mediated cervical carcinogenesis 
                                 
                                                            
 
                           
                          
                              
                           
                                                    
                            Publications:  
                           
                          
                            
	
		
			
				1. 
			
				Mallick, S., Agarwal, J., Kannan, S., Pawar, S., Kane, S. and Teni, T.   PCNA and anti-apoptotic Mcl-1 proteins predict disease-free survival in oral cancer patients treated with definitive radiotherapy. Oral Oncology.  2010.  46, 688-693. [PubMed]  
		 
		
			
				2. 
			
				Mallick, S., Patil, R., Gyanchandani, R., Pawar, S., Palve, V., Kannan, S., Pathak, K. A., Choudhary, M. and Teni, T. R.   Human oral cancers have altered expression of Bcl-2 family members and increased expression of the anti-apoptotic splice variant of Mcl-1. The Journal of Pathology.  2009.  217, 398-407. [PubMed]  
		 
		
			
				3. 
			
				Teni, T. , Pawar, S., Sanghvi, V. and Saranath, D.  Expression of bcl-2 and bax in chewing tobacco-induced oral cancers and oral lesions from India. Pathology Oncology Research : POR.  2002.  8, 109-114. [PubMed]  
		 
		
			
				4. 
			
				Teni, T. R. , Saranath, D., Mahale, A. M., Pai, S. A., Ahire, S. D. and Ingle, A. D.  Induction of lymphomas on implantation of human oral squamous cell carcinomas in nude mice. Indian Journal of Experimental Biology.  2001.  39, 111-118. [PubMed]  
		 
		
			
				5. 
			
				Saranath, D., Tandle, A. T., Teni, T. R. , Dedhia, P. M., Borges, A. M., Parikh, D., Sanghavi, V. and Mehta, A. R.  p53 inactivation in chewing tobacco-induced oral cancers and leukoplakias from India. Oral Oncology.  1999.  35, 242-250. [PubMed]  
		 
		
			
				6. 
			
				Sheth, N. A., Teni, T. R.  and Mundle, S. D.  Dual regulatory action of prostatic inhibin (10.7 kDa) on DNA synthesis. Indian Journal of Experimental Biology.  1992.  30, 1024-1029. [PubMed]  
		 
		
			
				7. 
			
				Teni, T. R., Sampat, M. B. and Sheth, N. A.  Inhibin (10.7 kD prostatic peptide) in normal, hyperplastic, and malignant human endometria: an immunohistochemical study. The Journal of Pathology.  1992.  168, 35-40. [PubMed]  
		 
		
			
				8. 
			
				Mundle, S. D., Teni, T. R.  and Sheth, N. A.  Inhibition of PHA-stimulated proliferation of peripheral blood mononuclear cells by human seminal plasma inhibin (HSPI). Journal of Clinical & Laboratory Immunology.  1992.  38, 187-193. [PubMed]  
		 
		
			
				9. 
			
				Teni, T. R. , Bandivdekar, A. H., Sheth, A. R. and Sheth, N. A.  Prostatic inhibin-like peptide quantified in urine of prostatic cancer patients by enzyme-linked immunosorbent assay. Clinical Chemistry.  1989.  35, 1376-1379. [PubMed]  
		 
		
			
				10. 
			
				Teni, T. R. , Sheth, A. R., Kamath, M. R. and Sheth, N. A.  Serum and urinary prostatic inhibin-like peptide in benign prostatic hyperplasia and carcinoma of prostate. Cancer Letters.  1988.  43, 9-14. [PubMed]  
		 
		
			
				11. 
			
				Teni, T. R. , Sheth, A. R. and Sheth, N. A.  Modulation of rat prostatic inhibinlike peptide (PIP) by steroids and protein hormones. Archives of Andrology.  1988.  20, 211-217. [PubMed]  
		 
		
			
				12. 
			
				Teni, T. , Pawar, S., Sanghvi, V. and Saranath, D.  Expression of bcl-2 and bax in chewing tobacco-induced oral cancers and oral lesions from India. Pathology Oncology Research : POR.  2002.  8, 109-114. [PubMed]  
		 
		
			
				13. 
			
				Saranath, D., Tandle, A. T., Teni, T. R. , Dedhia, P. M., Borges, A. M., Parikh, D., Sanghavi, V. and Mehta, A. R.  p53 inactivation in chewing tobacco-induced oral cancers and leukoplakias from India. Oral Oncology.  1999.  35, 242-250. [PubMed]  
		 
		
			
				14. 
			
				Teni T , Pawar S, Sanghvi V and Saranath D. Expression of bcl-2 and bax in chewing tobacco-induced oral cancers and oral lesions from India. Pathology & Oncology Research . 2002;8(2):109-14. 
		 
	 
	 
  
                           
                         
                                                    
                            Grant Support:  
                           
                                                    
                            
                                
                                  Project Title  
                                  Role  
                                  Funding Agency   
                                  Sanction Number  
                                  Sanction Date  
                                 
                                                                
                                  Study of the expression of apoptosis-related genes in human oral cancers and cell lines. 
                                  Principal Investigator 
                                   
                                   
                                  
                                  
								  
								  
								  
								  
								  
								  
								  
								  								   
                                 
                                                                
                                  Role of anti-apoptotic Mcl-1 gene in human oral cancers/cell lines and premalignant lesions  
                                  Principal Investigator 
                                   
                                   
                                  
                                  
								  
								  
								  
								  
								  
								  
								  
								  								   
                                 
                                                                
                                  Molecular assessment of surgical margins for prediction of recurrence of gingivo-buccal oral cancers: a retrospective study 
                                  Principal Investigator 
                                   
                                   
                                  
                                  
								  
								  
								  
								  
								  
								  
								  
								  								   
                                 
                                                                
                                  The Presence of HPV-16 DNA in Peripheral Blood of Oropharyngeal Carcinoma Patients as a Marker for Disease Recurrence 
                                  Principal Investigator 
                                   
                                   
                                  
                                  
								  
								  
								  
								  
								  
								  
								  
								  								   
                                 
                                                                
                                  Molecular Markers for the detection and progression of Cervical Cancer 
                                  Co-PI 
                                   
                                   
                                  
                                  
								  
								  
								  
								  
								  
								  
								  
								  								   
                                 
                                                              
                                 
 
                           
                          
                              
                           
                                                
 
                      
                          
                        
                            
                               
                             
                            
                                                                
                                  
                                    
                                      Type of Neoplasms 
 
                                     
                                                                        
                                        
                                     
                                    
                                      Head and Neck 
 
                                     
									                                    
                                      
                                          Oral cavity                                      
 
                                     
                                                                                                                                                                                                                                                                                                                                                                                                            
                                      Female genital system 
 
                                     
									                                    
                                      
                                          Cervix