Tanuja R. Teni, Ph.D.
Assistant Professor
Advanced Centre for Treatment Research and Education in Cancer
Teni Lab
Tata Memorial Centre, Kharghar
Navi Mumbai - 410 210.
Maharashtra
E-mail: tteni@actrec.gov.in
Phone: +91-22-27405071
Fax: +91-22-27405085
URL: http://actrec.gov.in/pi-webpages/TanujaTeni/tanuja-index.htm
Area of Specialization:
Molecular Biology
Research Summary:
Molecular analysis of apoptosis signaling pathways in oral cancer
Molecular basis of oral submucous fibrosis and leukoplakias
Recurrence and radiation response-associated genes in oral and cervical cancers – biomarkers and therapeutic targets
Regulation of NF-kappaB signaling pathway in HPV-mediated cervical carcinogenesis
Publications:
1.
Mallick, S., Agarwal, J., Kannan, S., Pawar, S., Kane, S. and Teni, T. PCNA and anti-apoptotic Mcl-1 proteins predict disease-free survival in oral cancer patients treated with definitive radiotherapy. Oral Oncology. 2010. 46, 688-693. [PubMed]
2.
Mallick, S., Patil, R., Gyanchandani, R., Pawar, S., Palve, V., Kannan, S., Pathak, K. A., Choudhary, M. and Teni, T. R. Human oral cancers have altered expression of Bcl-2 family members and increased expression of the anti-apoptotic splice variant of Mcl-1. The Journal of Pathology. 2009. 217, 398-407. [PubMed]
3.
Teni, T. , Pawar, S., Sanghvi, V. and Saranath, D. Expression of bcl-2 and bax in chewing tobacco-induced oral cancers and oral lesions from India. Pathology Oncology Research : POR. 2002. 8, 109-114. [PubMed]
4.
Teni, T. R. , Saranath, D., Mahale, A. M., Pai, S. A., Ahire, S. D. and Ingle, A. D. Induction of lymphomas on implantation of human oral squamous cell carcinomas in nude mice. Indian Journal of Experimental Biology. 2001. 39, 111-118. [PubMed]
5.
Saranath, D., Tandle, A. T., Teni, T. R. , Dedhia, P. M., Borges, A. M., Parikh, D., Sanghavi, V. and Mehta, A. R. p53 inactivation in chewing tobacco-induced oral cancers and leukoplakias from India. Oral Oncology. 1999. 35, 242-250. [PubMed]
6.
Sheth, N. A., Teni, T. R. and Mundle, S. D. Dual regulatory action of prostatic inhibin (10.7 kDa) on DNA synthesis. Indian Journal of Experimental Biology. 1992. 30, 1024-1029. [PubMed]
7.
Teni, T. R., Sampat, M. B. and Sheth, N. A. Inhibin (10.7 kD prostatic peptide) in normal, hyperplastic, and malignant human endometria: an immunohistochemical study. The Journal of Pathology. 1992. 168, 35-40. [PubMed]
8.
Mundle, S. D., Teni, T. R. and Sheth, N. A. Inhibition of PHA-stimulated proliferation of peripheral blood mononuclear cells by human seminal plasma inhibin (HSPI). Journal of Clinical & Laboratory Immunology. 1992. 38, 187-193. [PubMed]
9.
Teni, T. R. , Bandivdekar, A. H., Sheth, A. R. and Sheth, N. A. Prostatic inhibin-like peptide quantified in urine of prostatic cancer patients by enzyme-linked immunosorbent assay. Clinical Chemistry. 1989. 35, 1376-1379. [PubMed]
10.
Teni, T. R. , Sheth, A. R., Kamath, M. R. and Sheth, N. A. Serum and urinary prostatic inhibin-like peptide in benign prostatic hyperplasia and carcinoma of prostate. Cancer Letters. 1988. 43, 9-14. [PubMed]
11.
Teni, T. R. , Sheth, A. R. and Sheth, N. A. Modulation of rat prostatic inhibinlike peptide (PIP) by steroids and protein hormones. Archives of Andrology. 1988. 20, 211-217. [PubMed]
12.
Teni, T. , Pawar, S., Sanghvi, V. and Saranath, D. Expression of bcl-2 and bax in chewing tobacco-induced oral cancers and oral lesions from India. Pathology Oncology Research : POR. 2002. 8, 109-114. [PubMed]
13.
Saranath, D., Tandle, A. T., Teni, T. R. , Dedhia, P. M., Borges, A. M., Parikh, D., Sanghavi, V. and Mehta, A. R. p53 inactivation in chewing tobacco-induced oral cancers and leukoplakias from India. Oral Oncology. 1999. 35, 242-250. [PubMed]
14.
Teni T , Pawar S, Sanghvi V and Saranath D. Expression of bcl-2 and bax in chewing tobacco-induced oral cancers and oral lesions from India. Pathology & Oncology Research . 2002;8(2):109-14.
Grant Support:
Project Title
Role
Funding Agency
Sanction Number
Sanction Date
Study of the expression of apoptosis-related genes in human oral cancers and cell lines.
Principal Investigator
Role of anti-apoptotic Mcl-1 gene in human oral cancers/cell lines and premalignant lesions
Principal Investigator
Molecular assessment of surgical margins for prediction of recurrence of gingivo-buccal oral cancers: a retrospective study
Principal Investigator
The Presence of HPV-16 DNA in Peripheral Blood of Oropharyngeal Carcinoma Patients as a Marker for Disease Recurrence
Principal Investigator
Molecular Markers for the detection and progression of Cervical Cancer
Co-PI
Type of Neoplasms
Head and Neck
Oral cavity
Female genital system
Cervix