INCREDB ID : 477
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Manjunath B Joshi, Ph.D.
Assistant Professor 
 
Manipal University
School of Life Sciences,
Manipal - 576 104   
Karnataka   
 
E-mail: joshmanjunath@gmail.com
 
Positions Held:
Position Affiliation Time Period
Post Doctoral Fellow 2007-2011
 
Publications:
1. Joshi, M. B., Lad, A., Bharath, P., Balakrishnan, A., Ramachandra, L. and Satyamoorthy, K.  High glucose modulates IL-6 mediated immune homeostasis through impeding neutrophil extracellular trap formation. FEBS Letters. 2013.  587, 2241-2246. [PubMed]
2. Ellmann, L., Joshi, M. B., Resink, T. J., Bosserhoff, A. K. and Kuphal, S.  BRN2 is a transcriptional repressor of CDH13 (T-cadherin) in melanoma cells. Laboratory Investigation; A Journal of Technical Methods and Pathology. 2012.  92, 1788-1800. [PubMed]
3. Kyriakakis, E., Maslova, K., Philippova, M., Pfaff, D., Joshi, M. B., Buechner, S. A., Erne, P. and Resink, T. J.  T-Cadherin is an auxiliary negative regulator of EGFR pathway activity in cutaneous squamous cell carcinoma: impact on cell motility. The Journal of Investigative Dermatology. 2012.  132, 2275-2285. [PubMed]
4. Philippova, M., Joshi, M. B., Pfaff, D., Kyriakakis, E., Maslova, K., Erne, P. and Resink, T. J.  T-cadherin attenuates insulin-dependent signalling, eNOS activation, and angiogenesis in vascular endothelial cells. Cardiovascular Research. 2012.  93, 498-507. [PubMed]
5. Philippova, M., Suter, Y., Toggweiler, S., Schoenenberger, A. W., Joshi, M. B., Kyriakakis, E., Erne, P. and Resink, T. J.  T-cadherin is present on endothelial microparticles and is elevated in plasma in early atherosclerosis. European Heart Journal. 2011.  32, 760-771. [PubMed]
6. Gupta, A. K., Joshi, M. B., Philippova, M., Erne, P., Hasler, P., Hahn, S. and Resink, T. J.  Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell death. FEBS Letters. 2010.  584, 3193-3197. [PubMed]
7. Kyriakakis, E., Philippova, M., Joshi, M. B., Pfaff, D., Bochkov, V., Afonyushkin, T., Erne, P. and Resink, T. J.  T-cadherin attenuates the PERK branch of the unfolded protein response and protects vascular endothelial cells from endoplasmic reticulum stress-induced apoptosis. Cellular Signalling. 2010.  22, 1308-1316. [PubMed]
8. Joshi, M. B., Kyriakakis, E., Pfaff, D., Rupp, K., Philippova, M., Erne, P. and Resink, T. J.  Extracellular cadherin repeat domains EC1 and EC5 of T-cadherin are essential for its ability to stimulate angiogenic behavior of endothelial cells. FASEB Journal : Official Publication of the Federation of American Societies For Experimental Biology. 2009.  23, 4011-4021. [PubMed]
9. Philippova, M., Joshi, M. B., Kyriakakis, E., Pfaff, D., Erne, P. and Resink, T. J.  A guide and guard: the many faces of T-cadherin. Cellular Signalling. 2009.  21, 1035-1044. [PubMed]
10. Resink, T. J., Philippova, M., Joshi, M. B., Kyriakakis, E. and Erne, P.  Cadherins and cardiovascular disease. Swiss Medical Weekly. 2009.  139, 122-134. [PubMed]
11. Joshi, M. B., Ivanov, D., Philippova, M., Kyriakakis, E., Erne, P. and Resink, T. J.  A requirement for thioredoxin in redox-sensitive modulation of T-cadherin expression in endothelial cells. The Biochemical Journal. 2008.  416, 271-280. [PubMed]
12. Philippova, M., Ivanov, D., Joshi, M. B., Kyriakakis, E., Rupp, K., Afonyushkin, T., Bochkov, V., Erne, P. and Resink, T. J.  Identification of proteins associating with glycosylphosphatidylinositol- anchored T-cadherin on the surface of vascular endothelial cells: role for Grp78/BiP in T-cadherin-dependent cell survival. Molecular and Cellular Biology. 2008.  28, 4004-4017. [PubMed]
13. Rout, P. K., Joshi, M. B., Mandal, A., Laloe, D., Singh, L. and Thangaraj, K.  Microsatellite-based phylogeny of Indian domestic goats. BMC Genetics. 2008.  9, 11. [PubMed]
14. Ghosh, S., Joshi, M. B., Ivanov, D., Feder-Mengus, C., Spagnoli, G. C., Martin, I., Erne, P. and Resink, T. J.  Use of multicellular tumor spheroids to dissect endothelial cell-tumor cell interactions: a role for T-cadherin in tumor angiogenesis. FEBS Letters. 2007.  581, 4523-4528. [PubMed]
15. Joshi, M. B., Ivanov, D., Philippova, M., Erne, P. and Resink, T. J.  Integrin-linked kinase is an essential mediator for T-cadherin-dependent signaling via Akt and GSK3beta in endothelial cells. FASEB Journal : Official Publication of the Federation of American Societies For Experimental Biology. 2007.  21, 3083-3095. [PubMed]
16. Joshi, M. B., Philippova, M., Ivanov, D., Allenspach, R., Erne, P. and Resink, T. J.  T-cadherin protects endothelial cells from oxidative stress-induced apoptosis. FASEB Journal : Official Publication of the Federation of American Societies For Experimental Biology. 2005.  19, 1737-1739. [PubMed]
17. Joshi, M. B., Rout, P. K., Mandal, A. K., Tyler-Smith, C., Singh, L. and Thangaraj, K.  Phylogeography and origin of Indian domestic goats. Molecular Biology and Evolution. 2004.  21, 454-462. [PubMed]
18. Thangaraj, K., Joshi, M. B., Reddy, A. G., Rasalkar, A. A. and Singh, L.  Sperm mitochondrial mutations as a cause of low sperm motility. Journal of Andrology. 2003.  24, 388-392. [PubMed]
19. Thangaraj, K., Joshi, M. B., Reddy, A. G., Gupta, N. J., Chakravarty, B. and Singh, L.  CAG repeat expansion in the androgen receptor gene is not associated with male infertility in Indian populations. Journal of Andrology. 2002.  23, 815-818. [PubMed]
 

 
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Education 
::
Ph.D. in Medical Biotechnology, Cardiovascular Laboratory, University Hospital, Basel, Switzerland, 2003-2007
  Last modified on : Jan 3, 2014
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