Mahesh J Kulkarni, Ph.D.
Scientist
Dr. Homi Bhabha Road
Pune - 411 008
Maharashtra
E-mail: mj.kulkarni@ncl.res.in
Phone: +91-20-25902541
Fax: +91-20-25902648
URL: http://www.ncl-india.org/files/Research/ScientistProfile/Default.aspx?menuid=ql8&Id=5&NCLEmpId=2365&UserId=47
Publications:
1.
Kesavan, S. K., Bhat, S., Golegaonkar, S. B., Jagadeeshaprasad, M. G., Deshmukh, A. B., Patil, H. S., Bhosale, S. D., Shaikh, M. L., Thulasiram, H. V., Boppana, R. and Kulkarni, M. J. Proteome wide reduction in AGE modification in streptozotocin induced diabetic mice by hydralazine mediated transglycation. Scientific Reports. 2013. 3, 2941. [PubMed]
2.
Joglekar, M. M., Panaskar, S. N., Chougale, A. D., Kulkarni, M. J. and Arvindekar, A. U. A novel mechanism for antiglycative action of limonene through stabilization of protein conformation. Molecular BioSystems. 2013. 9, 2463-2472. [PubMed]
3.
Jangale, N. M., Devarshi, P. P., Dubal, A. A., Ghule, A. E., Koppikar, S. J., Bodhankar, S. L., Chougale, A. D., Kulkarni, M. J. and Harsulkar, A. M. Dietary flaxseed oil and fish oil modulates expression of antioxidant and inflammatory genes with alleviation of protein glycation status and inflammation in liver of streptozotocin-nicotinamide induced diabetic rats. Food Chemistry. 2013. 141, 187-195. [PubMed]
4.
Korwar, A. M., Bhonsle, H. S., Ghole, V. S., Gawai, K. R., Koppikar, C. B. and Kulkarni, M. J. Proteomic profiling and interactome analysis of ER-positive/HER2/neu negative invasive ductal carcinoma of the breast: towards proteomics biomarkers. Omics : A Journal of Integrative Biology. 2013. 17, 27-40. [PubMed]
5.
Bhonsle, H. S., Korwar, A. M., Chougale, A. D., Kote, S. S., Dhande, N. L., Shelgikar, K. M. and Kulkarni, M. J. Proteomic study reveals downregulation of apolipoprotein A1 in plasma of poorly controlled diabetes: a pilot study. Molecular Medicine Reports. 2013. 7, 495-498. [PubMed]
6.
Kulkarni, M. J., Korwar, A. M., Mary, S., Bhonsle, H. S. and Giri, A. P. Glycated proteome: from reaction to intervention. Proteomics. Clinical Applications. 2013. 7, 155-170. [PubMed]
7.
Mishra, M., Mahajan, N., Tamhane, V. A., Kulkarni, M. J., Baldwin, I. T., Gupta, V. S. and Giri, A. P. Stress inducible proteinase inhibitor diversity in Capsicum annuum. BMC Plant Biology. 2012. 12, 217. [PubMed]
8.
Bansode, S. B., Chougale, A. D., Joshi, R. S., Giri, A. P., Bodhankar, S. L., Harsulkar, A. M. and Kulkarni, M. J. Proteomic analysis of protease resistant proteins in the diabetic rat kidney. Molecular & Cellular Proteomics : MCP. 2013. 12, 228-236. [PubMed]
9.
Mary, S., Patil, G. V., Kulkarni, A. V., Kulkarni, M. J., Joshi, S. R., Mehendale, S. S. and Giri, A. P. Dynamic proteome in enigmatic preeclampsia: an account of molecular mechanisms and biomarker discovery. Proteomics. Clinical Applications. 2012. 6, 79-90. [PubMed]
10.
Korwar, A. M., Bhonsle, H. S., Chougale, A. D., Kote, S. S., Gawai, K. R., Ghole, V. S., Koppikar, C. B. and Kulkarni, M. J. Analysis of AGE modified proteins and RAGE expression in HER2/neu negative invasive ductal carcinoma. Biochemical and Biophysical Research Communications. 2012. 419, 490-494. [PubMed]
11.
Bhonsle, H. S., Korwar, A. M., Kesavan, S. K., Bhosale, S. D., Bansode, S. B. and Kulkarni, M. J. "Zoom-ln"--A targeted database search for identification of glycation modifications analyzed by untargeted tandem mass spectrometry. European Journal of Mass Spectrometry. 2012. 18, 475-481. [PubMed]
12.
Bhonsle, H. S., Korwar, A. M., Kote, S. S., Golegaonkar, S. B., Chougale, A. D., Shaik, M. L., Dhande, N. L., Giri, A. P., Shelgikar, K. M., Boppana, R. and Kulkarni, M. J. Low plasma albumin levels are associated with increased plasma protein glycation and HbA1c in diabetes. Journal of Proteome Research. 2012. 11, 1391-1396. [PubMed]
13.
Suresh, K. K., Bhosale, S. D., Thulasiram, H. V. and Kulkarni, M. J. Comparative and chemical proteomic approaches reveal gatifloxacin deregulates enzymes involved in glucose metabolism. The Journal of Toxicological Sciences. 2011. 36, 787-796. [PubMed]
14.
Chougale, A. D., Bhat, S. P., Bhujbal, S. V., Zambare, M. R., Puntambekar, S., Somani, R. S., Boppana, R., Giri, A. P. and Kulkarni, M. J. Proteomic analysis of glycated proteins from streptozotocin-induced diabetic rat kidney. Molecular Biotechnology. 2012. 50, 28-38. [PubMed]
15.
Mishra, M., Tamhane, V. A., Khandelwal, N., Kulkarni, M. J., Gupta, V. S. and Giri, A. P. Interaction of recombinant CanPIs with Helicoverpa armigera gut proteases reveals their processing patterns, stability and efficiency. Proteomics. 2010. 10, 2845-2857. [PubMed]
16.
Golegaonkar, S. B., Bhonsle, H. S., Boppana, R. and Kulkarni, M. J. Discovery of rifampicin as a new anti-glycating compound by matrix-assisted laser desorption/ionization mass spectrometry-based insulin glycation assay. European Journal of Mass Spectrometry. 2010. 16, 221-226. [PubMed]
17.
Dhaneshwar, S. R., Mahadik, M. V. and Kulkarni, M. J. Column liquid chromatography-ultraviolet and column liquid chromatography/mass spectrometry evaluation of stress degradation behavior of escitalopram oxalate. Journal of AOAC International. 2009. 92, 138-147. [PubMed]
18.
Bhonsle, H. S., Singh, S. K., Srivastava, G., Boppana, R. and Kulkarni, M. J. Albumin competitively inhibits glycation of less abundant proteins. Protein and Peptide Letters. 2008. 15, 663-667. [PubMed]
19.
Shabab, M., Kulkarni, M. J. and Khan, M. I. Study of papain-cystatin interaction by intensity fading MALDI-TOF-MS. The Protein Journal. 2008. 27, 7-12. [PubMed]
20.
Bar, C., Patil, R., Doshi, J., Kulkarni, M. J. and Gade, W. N. Characterization of the proteins of bacterial strain isolated from contaminated site involved in heavy metal resistance--a proteomic approach. Journal of Biotechnology. 2007. 128, 444-451. [PubMed]
21.
Kulkarni, M. J., Vinod, V. P., Umasankar, P. K., Patole, M. S. and Rao, M. Intact cell matrix-assisted laser desorption/ionization mass spectrometry as a tool to screen drugs in vivo for regulation of protein expression. Rapid Communications in Mass Spectrometry : RCM. 2006. 20, 2769-2772. [PubMed]
22.
Chumbalkar, V. C., Subhashini, C., Dhople, V. M., Sundaram, C. S., Jagannadham, M. V., Kumar, K. N., Srinivas, P. N., Mythili, R., Rao, M. K., Kulkarni, M. J., Hegde, S., Hegde, A. S., Samual, C., Santosh, V., Singh, L. and Sirdeshmukh, R. Differential protein expression in human gliomas and molecular insights. Proteomics. 2005. 5, 1167-1177. [PubMed]
My CV: Download
Education
::
Ph.D.
University of Agricultural Sciences, Bangalore
Honors and Awards
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NCL Research Foundation - Scientist of the year 2010
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Elected as Young Associate of Maharashtra Academy of Sciences, 2007
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Executive council member of Proteomics Society, India from 2009