INCREDB ID : 463
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Rajan R Dighe, Ph.D.
Professor 
 
Indian Institute of Science
Molecular Reproduction Development and Genetics Indian Institute of Science.
Bangalore - 560 012   
Karnataka   
 
E-mail: rdighe@mrdg.iisc.ernet.in
Phone:  91-80-22932998
Fax: 91-80-23600999
 
URL: http://mrdg.iisc.ernet.in/RRD_files/Research.htm
 
Publications:
1. Gadkari, R. A., Roy, S., Rekha, N., Srinivasan, N. and Dighe, R. R.  Identification of a heterodimer-specific epitope present in human chorionic gonadotrophin (hCG) using a monoclonal antibody that can distinguish between hCG and human LH. Journal of Molecular Endocrinology. 2005.  34, 879-887. [PubMed]
2. Joshi, A. R. and Dighe, R. R.  Expression of apoptotic genes in testicular germ cells and their modulation by luteinizing hormone. The Journal of Steroid Biochemistry and Molecular Biology. 2006.  101, 22-30. [PubMed]
3. Blanchard, V., Gadkari, R. A., Gerwig, G. J., Leeflang, B. R., Dighe, R. R. and Kamerling, J. P.  Characterization of the N-linked oligosaccharides from human chorionic gonadotropin expressed in the methylotrophic yeast Pichia pastoris. Glycoconjugate Journal. 2007.  24, 33-47. [PubMed]
4. Gadkari, R. A., Sandhya, S., Sowdhamini, R. and Dighe, R. R.  The antigen binding sites of various hCG monoclonal antibodies show homology to different domains of LH receptor. Molecular and Cellular Endocrinology. 2007.  260-262, 23-32. [PubMed]
5. Pareek, T. K., Joshi, A. R., Sanyal, A. and Dighe, R. R.  Insights into male germ cell apoptosis due to depletion of gonadotropins caused by GnRH antagonists. Apoptosis : An International Journal On Programmed Cell Death. 2007.  12, 1085-1100. [PubMed]
6. Roy, S., Setlur, S., Gadkari, R. A., Krishnamurthy, H. N. and Dighe, R. R.  Translational fusion of two beta-subunits of human chorionic gonadotropin results in production of a novel antagonist of the hormone. Endocrinology. 2007.  148, 3977-3986. [PubMed]
7. Blanchard, V., Gadkari, R. A., George, A. V., Roy, S., Gerwig, G. J., Leeflang, B. R., Dighe, R. R., Boelens, R. and Kamerling, J. P.  High-level expression of biologically active glycoprotein hormones in Pichia pastoris strains--selection of strain GS115, and not X-33, for the production of biologically active N-glycosylated 15N-labeled phCG. Glycoconjugate Journal. 2008.  25, 245-257. [PubMed]

 

 

 
 
Education 
::
Ph.D.
  Last modified on : Dec 9, 2015
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