INCREDB ID : 453
Home >> Investigator Page Previous      Next
Manas Kumar Santra, Ph.D.
Scientist D 
 
National Centre for Cell Science
NCCS Complex, Pune University Campus
Ganeshkhind
Pune - 411 007   
Maharashtra   
 
E-mail: manas@nccs@res.in
Phone: +91-020-25708150
Fax: +91-020-25692259
 
Positions Held:
Position Affiliation Time Period
Post Doctoral Fellow
 
Publications:
1.Tripathy, S. K., Surada, R. K., Manne, R. K., Mobin, S. M., Santra, M. K. and Patra, S.  Synthesis, characterisation and biological activities of [(p-cym)RuX(pz4lut)]n+ and [{(p-cym)RuX}2(mu-pz4lut)]n+ (X = Cl, H2O and pz4lut = alpha,alpha,alpha',alpha'-tetra(pyrazol-1-yl)-2,6-lutidine). Dalton Transactions. 2013.  42, 14081-14091. [PubMed]
2.Kumar, P., Gorai, S., Santra, M. K., Mondal, B. and Manna, D.  DNA binding, nuclease activity and cytotoxicity studies of Cu(II) complexes of tridentate ligands. Dalton Transactions. 2012.  41, 7573-7581. [PubMed]
3.Santra, M. K., Banerjee, A., Krishnakumar, S. S., Rahaman, O. and Panda, D.  Multiple-probe analysis of folding and unfolding pathways of human serum albumin. Evidence for a framework mechanism of folding. European Journal of Biochemistry / FEBS. 2004.  271, 1789-1797. [PubMed]
4.Santra, M. K., Banerjee, A., Rahaman, O. and Panda, D.  Unfolding pathways of human serum albumin: evidence for sequential unfolding and folding of its three domains. International Journal of Biological Macromolecules. 2005.  37, 200-204. [PubMed]
5.Santra, M. K., Dasgupta, D. and Panda, D.  Pyrene excimer fluorescence of yeast alcohol dehydrogenase: a sensitive probe to investigate ligand binding and unfolding pathway of the enzyme. Photochemistry and Photobiology. 2006.  82, 480-486. [PubMed]
6.Mukherjee, A., Santra, M. K., Beuria, T. K. and Panda, D.  A natural osmolyte trimethylamine N-oxide promotes assembly and bundling of the bacterial cell division protein, FtsZ and counteracts the denaturing effects of urea. The FEBS Journal. 2005.  272, 2760-2772. [PubMed]
7.Beuria, T. K., Santra, M. K. and Panda, D.  Sanguinarine blocks cytokinesis in bacteria by inhibiting FtsZ assembly and bundling. Biochemistry. 2005.  44, 16584-16593. [PubMed]
8.Santra, M. K., Beuria, T. K., Banerjee, A. and Panda, D.  Ruthenium red-induced bundling of bacterial cell division protein, FtsZ. The Journal of Biological Chemistry. 2004.  279, 25959-25965. [PubMed]
9.Santra, M. K., Dasgupta, D. and Panda, D.  Deuterium oxide promotes assembly and bundling of FtsZ protofilaments. Proteins. 2005.  61, 1101-1110. [PubMed]
10.Panda, D., Rathinasamy, K., Santra, M. K. and Wilson, L.  Kinetic suppression of microtubule dynamic instability by griseofulvin: implications for its possible use in the treatment of cancer. Proceedings of the National Academy of Sciences of the United States of America. 2005.  102, 9878-9883. [PubMed]
11.Santra, M. K. and Panda, D.  Detection of an intermediate during unfolding of bacterial cell division protein FtsZ: loss of functional properties precedes the global unfolding of FtsZ. The Journal of Biological Chemistry. 2003.  278, 21336-21343. [PubMed]
12.Beuria, T. K., Shah, J. H., Santra, M. K., Kumar, V. and Panda, D.  Effects of pH and ionic strength on the assembly and bundling of FtsZ protofilaments: a possible role of electrostatic interactions in the bundling of protofilaments. International Journal of Biological Macromolecules. 2006.  40, 30-39. [PubMed]
13.Santra, M. K. and Panda, D.  Acid-induced loss of functional properties of bacterial cell division protein FtsZ: evidence for an alternative conformation at acidic pH. Proteins. 2007.  67, 177-188. [PubMed]
14.Jedhe, G. S., Paul, D., Gonnade, R. G., Santra, M. K., Hamel, E., Nguyen, T. L. and Sanjayan, G. J.  Correlation of hydrogen-bonding propensity and anticancer profile of tetrazole-tethered combretastatin analogues. Bioorganic & Medicinal Chemistry Letters. 2013.  23, 4680-4684. [PubMed]
15.Paul, D., Kumar, A., Gajbhiye, A., Santra, M. K. and Srikanth, R.  Mass spectrometry-based proteomics in molecular diagnostics: discovery of cancer biomarkers using tissue culture. BioMed Research International. 2013.  2013, 783131. [PubMed]
16.Palakurthy, R. K., Wajapeyee, N., Santra, M. K., Gazin, C., Lin, L., Gobeil, S. and Green, M. R.  Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression. Molecular Cell. 2009.  36, 219-230. [PubMed]
17.Hart, D. O., Santra, M. K., Raha, T. and Green, M. R.  Selective interaction between Trf3 and Taf3 required for early development and hematopoiesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 2009.  238, 2540-2549. [PubMed]
18.Welch, C., Santra, M. K., El-Assaad, W., Zhu, X., Huber, W. E., Keys, R. A., Teodoro, J. G. and Green, M. R.  Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2. Cancer Research. 2009.  69, 6782-6789. [PubMed]
19.Santra, M. K., Wajapeyee, N. and Green, M. R.  F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage. Nature. 2009.  459, 722-725. [PubMed]
 
Education 
::
Ph.D. , 2001-2006
Honors and Awards
::
Charles A. King Trust Postdoctoral Research Fellowship Award, USA
::
Ramalingaswami Fellowship from Department of Biotechnology, Govt. of India
::
Innovative Young Biotechnologist Award from Department of Biotechnology, Govt. of India
::
Young Scientist Award in New Biology from Indian Science Congress Association
::
Best research scholar award from IIT Bombay
Member
::
Life member for the Society of Biological Chemists
::
Life member for Indian Association for Cancer Research
::
Life Member of Indian Science Congress Association
  Last modified on : Dec 3, 2013
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.