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Manas Kumar Santra, Ph.D.
Scientist D 
National Centre for Cell Science
NCCS Complex, Pune University Campus
Pune - 411 007   
Phone: +91-020-25708150
Fax: +91-020-25692259
Positions Held:
Position Affiliation Time Period
Post Doctoral Fellow
1.Tripathy, S. K., Surada, R. K., Manne, R. K., Mobin, S. M., Santra, M. K. and Patra, S.  Synthesis, characterisation and biological activities of [(p-cym)RuX(pz4lut)]n+ and [{(p-cym)RuX}2(mu-pz4lut)]n+ (X = Cl, H2O and pz4lut = alpha,alpha,alpha',alpha'-tetra(pyrazol-1-yl)-2,6-lutidine). Dalton Transactions. 2013.  42, 14081-14091. [PubMed]
2.Kumar, P., Gorai, S., Santra, M. K., Mondal, B. and Manna, D.  DNA binding, nuclease activity and cytotoxicity studies of Cu(II) complexes of tridentate ligands. Dalton Transactions. 2012.  41, 7573-7581. [PubMed]
3.Santra, M. K., Banerjee, A., Krishnakumar, S. S., Rahaman, O. and Panda, D.  Multiple-probe analysis of folding and unfolding pathways of human serum albumin. Evidence for a framework mechanism of folding. European Journal of Biochemistry / FEBS. 2004.  271, 1789-1797. [PubMed]
4.Santra, M. K., Banerjee, A., Rahaman, O. and Panda, D.  Unfolding pathways of human serum albumin: evidence for sequential unfolding and folding of its three domains. International Journal of Biological Macromolecules. 2005.  37, 200-204. [PubMed]
5.Santra, M. K., Dasgupta, D. and Panda, D.  Pyrene excimer fluorescence of yeast alcohol dehydrogenase: a sensitive probe to investigate ligand binding and unfolding pathway of the enzyme. Photochemistry and Photobiology. 2006.  82, 480-486. [PubMed]
6.Mukherjee, A., Santra, M. K., Beuria, T. K. and Panda, D.  A natural osmolyte trimethylamine N-oxide promotes assembly and bundling of the bacterial cell division protein, FtsZ and counteracts the denaturing effects of urea. The FEBS Journal. 2005.  272, 2760-2772. [PubMed]
7.Beuria, T. K., Santra, M. K. and Panda, D.  Sanguinarine blocks cytokinesis in bacteria by inhibiting FtsZ assembly and bundling. Biochemistry. 2005.  44, 16584-16593. [PubMed]
8.Santra, M. K., Beuria, T. K., Banerjee, A. and Panda, D.  Ruthenium red-induced bundling of bacterial cell division protein, FtsZ. The Journal of Biological Chemistry. 2004.  279, 25959-25965. [PubMed]
9.Santra, M. K., Dasgupta, D. and Panda, D.  Deuterium oxide promotes assembly and bundling of FtsZ protofilaments. Proteins. 2005.  61, 1101-1110. [PubMed]
10.Panda, D., Rathinasamy, K., Santra, M. K. and Wilson, L.  Kinetic suppression of microtubule dynamic instability by griseofulvin: implications for its possible use in the treatment of cancer. Proceedings of the National Academy of Sciences of the United States of America. 2005.  102, 9878-9883. [PubMed]
11.Santra, M. K. and Panda, D.  Detection of an intermediate during unfolding of bacterial cell division protein FtsZ: loss of functional properties precedes the global unfolding of FtsZ. The Journal of Biological Chemistry. 2003.  278, 21336-21343. [PubMed]
12.Beuria, T. K., Shah, J. H., Santra, M. K., Kumar, V. and Panda, D.  Effects of pH and ionic strength on the assembly and bundling of FtsZ protofilaments: a possible role of electrostatic interactions in the bundling of protofilaments. International Journal of Biological Macromolecules. 2006.  40, 30-39. [PubMed]
13.Santra, M. K. and Panda, D.  Acid-induced loss of functional properties of bacterial cell division protein FtsZ: evidence for an alternative conformation at acidic pH. Proteins. 2007.  67, 177-188. [PubMed]
14.Jedhe, G. S., Paul, D., Gonnade, R. G., Santra, M. K., Hamel, E., Nguyen, T. L. and Sanjayan, G. J.  Correlation of hydrogen-bonding propensity and anticancer profile of tetrazole-tethered combretastatin analogues. Bioorganic & Medicinal Chemistry Letters. 2013.  23, 4680-4684. [PubMed]
15.Paul, D., Kumar, A., Gajbhiye, A., Santra, M. K. and Srikanth, R.  Mass spectrometry-based proteomics in molecular diagnostics: discovery of cancer biomarkers using tissue culture. BioMed Research International. 2013.  2013, 783131. [PubMed]
16.Palakurthy, R. K., Wajapeyee, N., Santra, M. K., Gazin, C., Lin, L., Gobeil, S. and Green, M. R.  Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression. Molecular Cell. 2009.  36, 219-230. [PubMed]
17.Hart, D. O., Santra, M. K., Raha, T. and Green, M. R.  Selective interaction between Trf3 and Taf3 required for early development and hematopoiesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 2009.  238, 2540-2549. [PubMed]
18.Welch, C., Santra, M. K., El-Assaad, W., Zhu, X., Huber, W. E., Keys, R. A., Teodoro, J. G. and Green, M. R.  Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2. Cancer Research. 2009.  69, 6782-6789. [PubMed]
19.Santra, M. K., Wajapeyee, N. and Green, M. R.  F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage. Nature. 2009.  459, 722-725. [PubMed]
Ph.D. , 2001-2006
Honors and Awards
Charles A. King Trust Postdoctoral Research Fellowship Award, USA
Ramalingaswami Fellowship from Department of Biotechnology, Govt. of India
Innovative Young Biotechnologist Award from Department of Biotechnology, Govt. of India
Young Scientist Award in New Biology from Indian Science Congress Association
Best research scholar award from IIT Bombay
Life member for the Society of Biological Chemists
Life member for Indian Association for Cancer Research
Life Member of Indian Science Congress Association
  Last modified on : Dec 3, 2013
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.