INCREDB ID : 443
Home >> Investigator Page Previous      Next
Rupesh Dash, Ph.D.
Scientist 
 
Institute of Life Sciences
Nalco Square
Bhubaneswar - 751 023   
Orissa   
 
E-mail: rupesh.dash@gmail.com
Phone: +91-674 2301460 Ext. 285
Fax: +91-674 2300728
 
URL: http://www.ils.res.in/RD.php
 
Publications:
1.Dash, R., Bhoopathi, P., Das, S. K., Sarkar, S., Emdad, L., Dasgupta, S., Sarkar, D. and Fisher, P. B.  Novel mechanism of MDA-7/IL-24 cancer-specific apoptosis through SARI induction. Cancer Research. 2013.  [PubMed]
2.Azab, B. M., Dash, R., Das, S. K., Bhutia, S. K., Sarkar, S., Shen, X. N., Quinn, B. A., Dent, P., Dmitriev, I. P., Wang, X. Y., Curiel, D. T., Pellecchia, M., Reed, J. C., Sarkar, D. and Fisher, P. B.  Enhanced prostate cancer gene transfer and therapy using a novel serotype chimera cancer terminator virus (Ad.5/3-CTV). Journal of Cellular Physiology. 2014.  229, 34-43. [PubMed]
3.Li, Y. J., Liu, G., Li, Y., Vecchiarelli-Federico, L. M., Liu, J. C., Zacksenhaus, E., Shan, S. W., Yang, B. B., Li, Q., Dash, R., Fisher, P. B., Archer, M. C. and Ben-David, Y.  mda-7/IL-24 Expression inhibits breast cancer through upregulation of growth arrest-specific gene 3 (gas3) and disruption of beta1 integrin function. Molecular Cancer Research : MCR. 2013.  11, 593-603. [PubMed]
4.Das, S. K., Bhutia, S. K., Azab, B., Kegelman, T. P., Peachy, L., Santhekadur, P. K., Dasgupta, S., Dash, R., Dent, P., Grant, S., Emdad, L., Pellecchia, M., Sarkar, D. and Fisher, P. B.  MDA-9/syntenin and IGFBP-2 promote angiogenesis in human melanoma. Cancer Research. 2013.  73, 844-854. [PubMed]
5.Thomas, S., Quinn, B. A., Das, S. K., Dash, R., Emdad, L., Dasgupta, S., Wang, X. Y., Dent, P., Reed, J. C., Pellecchia, M., Sarkar, D. and Fisher, P. B.  Targeting the Bcl-2 family for cancer therapy. Expert Opinion On Therapeutic Targets. 2013.  17, 61-75. [PubMed]
6.Das, S. K., Sarkar, S., Dash, R., Dent, P., Wang, X. Y., Sarkar, D. and Fisher, P. B.  Chapter One---Cancer terminator viruses and approaches for enhancing therapeutic outcomes. Advances in Cancer Research. 2012.  115, 1-38. [PubMed]
7.Hedvat, M., Emdad, L., Das, S. K., Kim, K., Dasgupta, S., Thomas, S., Hu, B., Zhu, S., Dash, R., Quinn, B. A., Oyesanya, R. A., Kegelman, T. P., Sokhi, U. K., Sarkar, S., Erdogan, E., Menezes, M. E., Bhoopathi, P., Wang, X. Y., Pomper, M. G., Wei, J., Wu, B., Stebbins, J. L., Diaz, P. W., Reed, J. C., Pellecchia, M., Sarkar, D. and Fisher, P. B.  Selected approaches for rational drug design and high throughput screening to identify anti-cancer molecules. Anti-cancer Agents in Medicinal Chemistry. 2012.  12, 1143-1155. [PubMed]
8.Venkatesan, P., Bhutia, S. K., Singh, A. K., Das, S. K., Dash, R., Chaudhury, K., Sarkar, D., Fisher, P. B. and Mandal, M.  AEE788 potentiates celecoxib-induced growth inhibition and apoptosis in human colon cancer cells. Life Sciences. 2012.  91, 789-799. [PubMed]
9.Hingtgen, S., Kasmieh, R., Elbayly, E., Nesterenko, I., Figueiredo, J. L., Dash, R., Sarkar, D., Hall, D., Kozakov, D., Vajda, S., Fisher, P. B. and Shah, K.  A first-generation multi-functional cytokine for simultaneous optical tracking and tumor therapy. PloS One. 2012.  7, e40234. [PubMed]
10.Das, S. K., Bhutia, S. K., Kegelman, T. P., Peachy, L., Oyesanya, R. A., Dasgupta, S., Sokhi, U. K., Azab, B., Dash, R., Quinn, B. A., Kim, K., Barral, P. M., Su, Z. Z., Boukerche, H., Sarkar, D. and Fisher, P. B.  MDA-9/syntenin: a positive gatekeeper of melanoma metastasis. Frontiers in Bioscience. 2012.  17, 1-15. [PubMed]
11.Lee, S. G., Kim, K., Kegelman, T. P., Dash, R., Das, S. K., Choi, J. K., Emdad, L., Howlett, E. L., Jeon, H. Y., Su, Z. Z., Yoo, B. K., Sarkar, D., Kim, S. H., Kang, D. C. and Fisher, P. B.  Oncogene AEG-1 promotes glioma-induced neurodegeneration by increasing glutamate excitotoxicity. Cancer Research. 2011.  71, 6514-6523. [PubMed]
12.Quinn, B. A., Dash, R., Azab, B., Sarkar, S., Das, S. K., Kumar, S., Oyesanya, R. A., Dasgupta, S., Dent, P., Grant, S., Rahmani, M., Curiel, D. T., Dmitriev, I., Hedvat, M., Wei, J., Wu, B., Stebbins, J. L., Reed, J. C., Pellecchia, M., Sarkar, D. and Fisher, P. B.  Targeting Mcl-1 for the therapy of cancer. Expert Opinion On Investigational Drugs. 2011.  20, 1397-1411. [PubMed]
13.Kim, K., Lee, S. G., Kegelman, T. P., Su, Z. Z., Das, S. K., Dash, R., Dasgupta, S., Barral, P. M., Hedvat, M., Diaz, P., Reed, J. C., Stebbins, J. L., Pellecchia, M., Sarkar, D. and Fisher, P. B.  Role of excitatory amino acid transporter-2 (EAAT2) and glutamate in neurodegeneration: opportunities for developing novel therapeutics. Journal of Cellular Physiology. 2011.  226, 2484-2493. [PubMed]
14.Azab, B., Dash, R., Das, S. K., Bhutia, S. K., Shen, X. N., Quinn, B. A., Sarkar, S., Wang, X. Y., Hedvat, M., Dmitriev, I. P., Curiel, D. T., Grant, S., Dent, P., Reed, J. C., Pellecchia, M., Sarkar, D. and Fisher, P. B.  Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells. Journal of Cellular Physiology. 2012.  227, 2145-2153. [PubMed]
15.Bhutia, S. K., Das, S. K., Kegelman, T. P., Azab, B., Dash, R., Su, Z. Z., Wang, X. Y., Rizzi, F., Bettuzzi, S., Lee, S. G., Dent, P., Grant, S., Curiel, D. T., Sarkar, D. and Fisher, P. B.  mda-7/IL-24 differentially regulates soluble and nuclear clusterin in prostate cancer. Journal of Cellular Physiology. 2012.  227, 1805-1813. [PubMed]
16.Bhutia, S. K., Das, S. K., Azab, B., Dash, R., Su, Z. Z., Lee, S. G., Dent, P., Curiel, D. T., Sarkar, D. and Fisher, P. B.  Autophagy switches to apoptosis in prostate cancer cells infected with melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24). Autophagy. 2011.  7, 1076-1077. [PubMed]
17.Dash, R., Azab, B., Quinn, B. A., Shen, X., Wang, X. Y., Das, S. K., Rahmani, M., Wei, J., Hedvat, M., Dent, P., Dmitriev, I. P., Curiel, D. T., Grant, S., Wu, B., Stebbins, J. L., Pellecchia, M., Reed, J. C., Sarkar, D. and Fisher, P. B.  Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity. Proceedings of the National Academy of Sciences of the United States of America. 2011.  108, 8785-8790. [PubMed]
18.Dasgupta, S., Dash, R., Das, S. K., Sarkar, D. and Fisher, P. B.  Emerging strategies for the early detection and prevention of head and neck squamous cell cancer. Journal of Cellular Physiology. 2012.  227, 467-473. [PubMed]
19.Venkatesan, P., Puvvada, N., Dash, R., Prashanth, K., Sarkar, D., Azab, B., Pathak, A., Kundu, S. C., Fisher, P. B. and Mandal, M.  The potential of celecoxib-loaded hydroxyapatite-chitosan nanocomposite for the treatment of colon cancer. Biomaterials. 2011.  32, 3794-3806. [PubMed]
20.Dash, R., Azab, B., Shen, X. N., Sokhi, U. K., Sarkar, S., Su, Z. Z., Wang, X. Y., Claudio, P. P., Dent, P., Dmitriev, I. P., Curiel, D. T., Grant, S., Sarkar, D. and Fisher, P. B.  Developing an effective gene therapy for prostate cancer: New technologies with potential to translate from the laboratory into the clinic. Discovery Medicine. 2011.  11, 46-56. [PubMed]
21.Wei, J., Stebbins, J. L., Kitada, S., Dash, R., Zhai, D., Placzek, W. J., Wu, B., Rega, M. F., Zhang, Z., Barile, E., Yang, L., Dahl, R., Fisher, P. B., Reed, J. C. and Pellecchia, M.  An optically pure apogossypolone derivative as potent pan-active inhibitor of anti-apoptotic bcl-2 family proteins. Frontiers in Oncology. 2011.  1, 28. [PubMed]
22.Park, M. A., Hamed, H. A., Mitchell, C., Cruickshanks, N., Dash, R., Allegood, J., Dmitriev, I. P., Tye, G., Ogretmen, B., Spiegel, S., Yacoub, A., Grant, S., Curiel, D. T., Fisher, P. B. and Dent, P.  A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels. Molecular Pharmacology. 2011.  79, 368-380. [PubMed]
23.Dash, R., Bhutia, S. K., Azab, B., Su, Z. Z., Quinn, B. A., Kegelmen, T. P., Das, S. K., Kim, K., Lee, S. G., Park, M. A., Yacoub, A., Rahmani, M., Emdad, L., Dmitriev, I. P., Wang, X. Y., Sarkar, D., Grant, S., Dent, P., Curiel, D. T. and Fisher, P. B.  mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity. Cytokine & Growth Factor Reviews. 2010.  21, 381-391. [PubMed]
24.Rahmani, M., Mayo, M., Dash, R., Sokhi, U. K., Dmitriev, I. P., Sarkar, D., Dent, P., Curiel, D. T., Fisher, P. B. and Grant, S.  Melanoma differentiation associated gene-7/interleukin-24 potently induces apoptosis in human myeloid leukemia cells through a process regulated by endoplasmic reticulum stress. Molecular Pharmacology. 2010.  78, 1096-1104. [PubMed]
25.Dent, P., Yacoub, A., Hamed, H. A., Park, M. A., Dash, R., Bhutia, S. K., Sarkar, D., Wang, X. Y., Gupta, P., Emdad, L., Lebedeva, I. V., Sauane, M., Su, Z. Z., Rahmani, M., Broaddus, W. C., Young, H. F., Lesniak, M. S., Grant, S., Curiel, D. T. and Fisher, P. B.  The development of MDA-7/IL-24 as a cancer therapeutic. Pharmacology & Therapeutics. 2010.  128, 375-384. [PubMed]
26.Sarkar, S., Mazumdar, A., Dash, R., Sarkar, D., Fisher, P. B. and Mandal, M.  ZD6474 enhances paclitaxel antiproliferative and apoptotic effects in breast carcinoma cells. Journal of Cellular Physiology. 2011.  226, 375-384. [PubMed]
27.Huynh, K. M., Soh, J. W., Dash, R., Sarkar, D., Fisher, P. B. and Kang, D.  FOXM1 expression mediates growth suppression during terminal differentiation of HO-1 human metastatic melanoma cells. Journal of Cellular Physiology. 2011.  226, 194-204. [PubMed]
28.Dent, P., Yacoub, A., Hamed, H. A., Park, M. A., Dash, R., Bhutia, S. K., Sarkar, D., Gupta, P., Emdad, L., Lebedeva, I. V., Sauane, M., Su, Z. Z., Rahmani, M., Broaddus, W. C., Young, H. F., Lesniak, M., Grant, S., Curiel, D. T. and Fisher, P. B.  MDA-7/IL-24 as a cancer therapeutic: from bench to bedside. Anti-cancer Drugs. 2010.  21, 725-731. [PubMed]
29.Dash, R., Richards, J. E., Su, Z. Z., Bhutia, S. K., Azab, B., Rahmani, M., Dasmahapatra, G., Yacoub, A., Dent, P., Dmitriev, I. P., Curiel, D. T., Grant, S., Pellecchia, M., Reed, J. C., Sarkar, D. and Fisher, P. B.  Mechanism by which Mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokine. Cancer Research. 2010.  70, 5034-5045. [PubMed]
30.Wei, J., Stebbins, J. L., Kitada, S., Dash, R., Placzek, W., Rega, M. F., Wu, B., Cellitti, J., Zhai, D., Yang, L., Dahl, R., Fisher, P. B., Reed, J. C. and Pellecchia, M.  BI-97C1, an optically pure Apogossypol derivative as pan-active inhibitor of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins. Journal of Medicinal Chemistry. 2010.  53, 4166-4176. [PubMed]
31.Bhutia, S. K., Dash, R., Das, S. K., Azab, B., Su, Z. Z., Lee, S. G., Grant, S., Yacoub, A., Dent, P., Curiel, D. T., Sarkar, D. and Fisher, P. B.  Mechanism of autophagy to apoptosis switch triggered in prostate cancer cells by antitumor cytokine melanoma differentiation-associated gene 7/interleukin-24. Cancer Research. 2010.  70, 3667-3676. [PubMed]
32.Hamed, H. A., Yacoub, A., Park, M. A., Eulitt, P. J., Dash, R., Sarkar, D., Dmitriev, I. P., Lesniak, M. S., Shah, K., Grant, S., Curiel, D. T., Fisher, P. B. and Dent, P.  Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant glioma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2010.  18, 1130-1142. [PubMed]
33.Sarkar, S., Mazumdar, A., Dash, R., Sarkar, D., Fisher, P. B. and Mandal, M.  ZD6474, a dual tyrosine kinase inhibitor of EGFR and VEGFR-2, inhibits MAPK/ERK and AKT/PI3-K and induces apoptosis in breast cancer cells. Cancer Biology & Therapy. 2010.  9, 592-603. [PubMed]
34.Yacoub, A., Hamed, H. A., Allegood, J., Mitchell, C., Spiegel, S., Lesniak, M. S., Ogretmen, B., Dash, R., Sarkar, D., Broaddus, W. C., Grant, S., Curiel, D. T., Fisher, P. B. and Dent, P.  PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells. Cancer Research. 2010.  70, 1120-1129. [PubMed]
35.Emdad, L., Sarkar, D., Lee, S. G., Su, Z. Z., Yoo, B. K., Dash, R., Yacoub, A., Fuller, C. E., Shah, K., Dent, P., Bruce, J. N. and Fisher, P. B.  Astrocyte elevated gene-1: a novel target for human glioma therapy. Molecular Cancer Therapeutics. 2010.  9, 79-88. [PubMed]
36.Sauane, M., Su, Z. Z., Dash, R., Liu, X., Norris, J. S., Sarkar, D., Lee, S. G., Allegood, J. C., Dent, P., Spiegel, S. and Fisher, P. B.  Ceramide plays a prominent role in MDA-7/IL-24-induced cancer-specific apoptosis. Journal of Cellular Physiology. 2010.  222, 546-555. [PubMed]
37.Yacoub, A., Liu, R., Park, M. A., Hamed, H. A., Dash, R., Schramm, D. N., Sarkar, D., Dimitriev, I. P., Bell, J. K., Grant, S., Farrell, N. P., Curiel, D. T., Fisher, P. B. and Dent, P.  Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells. Molecular Pharmacology. 2010.  77, 298-310. [PubMed]
38.Tormo, D., Checinska, A., Alonso-Curbelo, D., Perez-Guijarro, E., Canon, E., Riveiro-Falkenbach, E., Calvo, T. G., Larribere, L., Megias, D., Mulero, F., Piris, M. A., Dash, R., Barral, P. M., Rodriguez-Peralto, J. L., Ortiz-Romero, P., Tuting, T., Fisher, P. B. and Soengas, M. S.  Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells. Cancer Cell. 2009.  16, 103-114. [PubMed]
39.Emdad, L., Lebedeva, I. V., Su, Z. Z., Gupta, P., Sauane, M., Dash, R., Grant, S., Dent, P., Curiel, D. T., Sarkar, D. and Fisher, P. B.  Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24. Cancer Biology & Therapy. 2009.  8, 391-400. [PubMed]
40.Dash, R., Acharya, C., Bindu, P. C. and Kundu, S. C.  Antioxidant potential of silk protein sericin against hydrogen peroxide-induced oxidative stress in skin fibroblasts. BMB Reports. 2008.  41, 236-241. [PubMed]
41.Dash, R., Mandal, M., Ghosh, S. K. and Kundu, S. C.  Silk sericin protein of tropical tasar silkworm inhibits UVB-induced apoptosis in human skin keratinocytes. Molecular and Cellular Biochemistry. 2008.  311, 111-119. [PubMed]
42.Dash, R., Ghosh, S. K., Kaplan, D. L. and Kundu, S. C.  Purification and biochemical characterization of a 70 kDa sericin from tropical tasar silkworm, Antheraea mylitta. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 2007.  147, 129-134. [PubMed]
43.Dash, R., Mukherjee, S. and Kundu, S. C.  Isolation, purification and characterization of silk protein sericin from cocoon peduncles of tropical tasar silkworm, Antheraea mylitta. International Journal of Biological Macromolecules. 2006.  38, 255-258. [PubMed]
44.Mahendran, B., Acharya, C., Dash, R., Ghosh, S. K. and Kundu, S. C.  Repetitive DNA in tropical tasar silkworm Antheraea mylitta. Gene. 2006.  370, 51-57. [PubMed]
 
Education 
::
Ph.D. , 2003-2008
  Last modified on : Dec 2, 2013
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.