INCREDB ID : 433
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Ritu Kulshreshtha, Ph.D.
Assistant Professor 
 
Indian Institute of Technology, Delhi
Dept. of Biochemical Engineering and Biotechnology
Room-134. Block I Dept. of Biochemical Engineering and Biotechnology Indian Institute of Technology
Delhi - 110 016   
New Delhi   
 
E-mail: drritukulshreshtha@gmail.com
Phone: 011-26591017
Fax: 011-26582282
 
URL: http://www.iitd.ac.in/content/ritu-kulshreshtha-biochemical
 
Positions Held:
Position Affiliation Time Period
Scientist Center for Plant Molecular Biology, Delhi University 2003
Post Doctoral Fellow Tufts-Medical Center, Boston, USA 2004-2008
Post Doctoral Fellow Harvard Medical School, Boston, USA 2008
Senior Research Associate School of Life Sciences, Jawaharlal Nehru University 2009
 
Area of Specialization:
Molecular Biology
Research Summary:
MicroRNA and Cancer Research
Hypoxia Cancer biology
 
Publications:
1. Sharma, S., Verma, S., Vasudevan, M., Samanta, S., Thakur, J. K. and Kulshreshtha, R.  The interplay of HuR and miR-3134 in regulation of AU rich transcriptome. RNA Biology. 2013.  10. [PubMed]
2. Nagpal, N., Ahmad, H. M., Molparia, B. and Kulshreshtha, R.  MicroRNA-191, an estrogen-responsive microRNA, functions as an oncogenic regulator in human breast cancer. Carcinogenesis. 2013.  [PubMed]
3. Vaz, C., Ahmad, H. M., Sharma, P., Gupta, R., Kumar, L., Kulshreshtha, R. and Bhattacharya, A.  Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood. BMC Genomics. 2010.  11, 288. [PubMed]
4. Srikantan, S., Abdelmohsen, K., Lee, E. K., Tominaga, K., Subaran, S. S., Kuwano, Y., Kulshrestha, R., Panchakshari, R., Kim, H. H., Yang, X., Martindale, J. L., Marasa, B. S., Kim, M. M., Wersto, R. P., Indig, F. E., Chowdhury, D. and Gorospe, M.  Translational control of TOP2A influences doxorubicin efficacy. Molecular and Cellular Biology. 2011.  31, 3790-3801. [PubMed]
5. Moskwa P, Buffa FM, Pan Y, Panchakshari R, Vischioni B, Gottipati P, Abdelmohsen K, Camps C, Ragoussis J, Kulshreshtha, R., Weinstock DM, Parker A, Pezzella F,  Gorospe M, Sharma RA, Helleday T, Harris AL, Chowdhury D. miR-182-mediated down-regulation of BRCA1 impacts on the DNA damage response and breast cancer therapy. Molecular Cell, 2011 Jan 21;41(2):210-20
6. Vaz, C., Ahmad, H. M., Sharma, P., Gupta, R., Kumar, L., Kulshreshtha, R. and Bhattacharya, A.  Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood. BMC Genomics. 2010.  11, 288. [PubMed]
7. Fasanaro, P., Greco, S., Lorenzi, M., Pescatori, M., Brioschi, M., Kulshreshtha, R., Banfi, C., Stubbs, A., Calin, G. A., Ivan, M., Capogrossi, M. C. and Martelli, F.  An integrated approach for experimental target identification of hypoxia-induced miR-210. The Journal of Biological Chemistry. 2009.  284, 35134-35143. [PubMed]
8. Crosby, M. E., Kulshreshtha, R., Ivan, M. and Glazer, P. M.  MicroRNA regulation of DNA repair gene expression in hypoxic stress. Cancer Research. 2009.  69, 1221-1229. [PubMed]
9. Ivan, M., Harris, A. L., Martelli, F. and Kulshreshtha, R.  Hypoxia response and microRNAs: no longer two separate worlds. Journal of Cellular and Molecular Medicine. 2008.  12, 1426-1431. [PubMed]
10. Kulshreshtha, R., Davuluri, R. V., Calin, G. A. and Ivan, M.  A microRNA component of the hypoxic response. Cell Death and Differentiation. 2008.  15, 667-671. [PubMed]
11. Kulshreshtha, R., Ferracin, M., Wojcik, S. E., Garzon, R., Alder, H., Agosto-Perez, F. J., Davuluri, R., Liu, C. G., Croce, C. M., Negrini, M., Calin, G. A. and Ivan, M.  A microRNA signature of hypoxia. Molecular and Cellular Biology. 2007.  27, 1859-1867. [PubMed]
12. Singh G, Jain M, Kulshreshtha, R., Khurana JP, Kumar S, Singh P. Expression analysis of genes encoding translation initiation factor 3 subunit g (TaeIF3g) and vesicle-associated membrane protein-associated protein (TaVAP) in drought tolerant and susceptible cultivars of wheat. 2007. Plant Science
13. Khurana JP and Kulshreshtha, R. Diversity in higher plant phytochromes and their molecular characteristics. (Invited Article). In: Souvenir-2nd International Congress of Plant Physiology, Jan 8-12, 2003, New Delhi, India, pp. 128-145
14. Kulshreshtha, R., Ferracin, M., Negrini, M., Calin, G. A., Davuluri, R. V. and Ivan, M.  Regulation of microRNA expression: the hypoxic component. Cell Cycle. 2007.  6, 1426-1431. [PubMed]
15. Kulshreshtha, R., Kumar, N., Balyan, H. S., Gupta, P. K., Khurana, P., Tyagi, A. K. and Khurana, J. P.  Structural characterization, expression analysis and evolution of the red/far-red sensing photoreceptor gene, phytochrome C (PHYC), localized on the 'B' genome of hexaploid wheat (Triticum aestivum L.). Planta. 2005.  221, 675-689. [PubMed]

 
Grant Support:
Project Title Role Funding Agency Sanction Number Sanction Date
Functional dissection of microRNAs frequently deregulated in solid cancers Investigator Department of Science & Technology, Government of India 2010-2013
MicroRNAs and AU rich elements (ARE): Deciphering the regulatory loop Investigator Department of Biotechnology, Government of India 2011-2014
Molecular Mechanisms of Hypoxia Resistance in Glioblastoma: Role of MicroRNAs Investigator Department of Biotechnology, Government of India 2011-2014
Investigating moduclation of miRNA expression in hypoxia-stem cell niche Investigator Department of Science & Technology, Government of India 2013-2014

 
 
My CV:   Download
 
Education 
::
Ph.D. in Plant Molecular Biology
Type of Neoplasms
Breast
  Last modified on : Jan 6, 2014
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