INCREDB ID : 422
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Partho Sarothi Ray, Ph.D.
Assistant Professor 
 
Indian Institute of Science Education and Research, Kolkata
Haringhata
P. O Mohanpur
Kolkata - 741 246   
West Bengal   
 
E-mail: psray@iiserkol.ac.in
Phone: 91 03473 279130, Extn. 228
 
URL: https://www.iiserkol.ac.in/component/sobipro/?pid=54&sid=160:Partho-Sarothi-Ray&Itemid=538
 
Positions Held:
Position Affiliation Time Period
Post Doctoral Fellow Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 2004-2008
Visiting Research Scholar Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 2008-2008
 
Area of Specialization:
Genetics
Molecular Biology
Oncology
Research Summary:
Role of microRNAs and regulatory proteins in chronic inflammation and cancer
 
Publications:
1. Yao, P., Potdar, A. A., Arif, A., Ray, P. S., Mukhopadhyay, R., Willard, B., Xu, Y., Yan, J., Saidel, G. M. and Fox, P. L.  Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression. Cell. 2012.  149, 88-100. [PubMed]
2. Bhat, P., Gnanasundram, S. V., Mani, P., Ray, P. S., Sarkar, D. P. and Das, S.  Targeting ribosome assembly on the HCV RNA using a small RNA molecule. RNA Biology. 2012.  9, 1110-1119. [PubMed]
3. Ray, P. S., Sullivan, J. C., Jia, J., Francis, J., Finnerty, J. R. and Fox, P. L.  Evolution of function of a fused metazoan tRNA synthetase. Molecular Biology and Evolution. 2011.  28, 437-447. [PubMed]
4. Chaudhury, A., Hussey, G. S., Ray, P. S., Jin, G., Fox, P. L. and Howe, P. H.  TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI. Nature Cell Biology. 2010.  12, 286-293. [PubMed]
5. Ray, P. S., Jia, J., Yao, P., Majumder, M., Hatzoglou, M. and Fox, P. L.  A stress-responsive RNA switch regulates VEGFA expression. Nature. 2009.  457, 915-919. [PubMed]
6. Mukhopadhyay, R., Jia, J., Arif, A., Ray, P. S. and Fox, P. L.  The GAIT system: a gatekeeper of inflammatory gene expression. Trends in Biochemical Sciences. 2009.  34, 324-331. [PubMed]
7. Mukhopadhyay, R., Ray, P. S., Arif, A., Brady, A. K., Kinter, M. and Fox, P. L.  DAPK-ZIPK-L13a axis constitutes a negative-feedback module regulating inflammatory gene expression. Molecular Cell. 2008.  32, 371-382. [PubMed]
8. Jia, J., Arif, A., Ray, P. S. and Fox, P. L.  WHEP domains direct noncanonical function of glutamyl-Prolyl tRNA synthetase in translational control of gene expression. Molecular Cell. 2008.  29, 679-690. [PubMed]
9. Grover, R., Ray, P. S. and Das, S.  Polypyrimidine tract binding protein regulates IRES-mediated translation of p53 isoforms. Cell Cycle. 2008.  7, 2189-2198. [PubMed]
10. Ray, P. S. and Fox, P. L.  A post-transcriptional pathway represses monocyte VEGF-A expression and angiogenic activity. The EMBO Journal. 2007.  26, 3360-3372. [PubMed]
11. Ray, P. S., Arif, A. and Fox, P. L.  Macromolecular complexes as depots for releasable regulatory proteins. Trends in Biochemical Sciences. 2007.  32, 158-164. [PubMed]
12. Ray, P. S., Grover, R. and Das, S.  Two internal ribosome entry sites mediate the translation of p53 isoforms. EMBO Reports. 2006.  7, 404-410. [PubMed]
13. Ray, P. S. and Fox, P. L.  Equality of the sexes: found in translation. Cell. 2005.  122, 492-493. [PubMed]
14. Ray, P. S. and Das, S.  Inhibition of hepatitis C virus IRES-mediated translation by small RNAs analogous to stem-loop structures of the 5'-untranslated region. Nucleic Acids Research. 2004.  32, 1678-1687. [PubMed]
15. Venkatramana, M., Ray, P. S., Chadda, A. and Das, S.  A 25 kDa cleavage product of polypyrimidine tract binding protein (PTB) present in mouse tissues prevents PTB binding to the 5' untranslated region and inhibits translation of hepatitis A virus RNA. Virus Research. 2003.  98, 141-149. [PubMed]
16. Seshagiri, P. B., Thomas, M., Sreekumar, A., Ray, P. and Mariappa, D.  Pentoxifylline induced signalling events during capacitation of hamster spermatozoa: significance of protein tyrosine phosphorylation. Cellular and Molecular Biology. 2003.  49, 371-380. [PubMed]
17. Ray, P. S. and Das, S.  La autoantigen is required for the internal ribosome entry site-mediated translation of Coxsackievirus B3 RNA. Nucleic Acids Research. 2002.  30, 4500-4508. [PubMed]
 

1. Fox P.L. Ray P.S., Arif A. and Jie J. Non-canonical functions of Aminoacyl-tRNA synthesases in translational control. In Translational Control in Biology and Medicine. Eds. Sonenberg N., Hershey J. and Mathews M. Cold Spring Harbor Library press. 2006. 829-854.
Grant Support:
Project Title Role Funding Agency Sanction Number Sanction Date
Molecular interactions in the post-transcriptional regulation of inflammatory gene expression Principal Investigator DBT-Wellcome Trust India Alliance Intermediate Fellowship 2011-2016

 
 
My CV:   Download
 
Education 
::
Ph.D. in Cancer Biology, Indian Institute of Science, Bangalore, India
::
M.Sc. in Life Sciences, Indian Institute of Science, Bangalore, India
Honors and Awards
::
DBT-Wellcome Trust India Alliance Intermediate Fellowship, 2011.
::
Associate, Indian Academy of Sciences, 2010.
::
Symposium Fellowship Award at the 74th Cold Spring Harbor Symposium on Quantitative Biology: Evolution, the Molecular Landscape, 2009.
::
The Elsa Albrecht Fellow Award, 2008, from the Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, USA.
  Last modified on : Dec 9, 2015
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