INCREDB ID : 399
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Sartaj Tabassum, Ph.D.
Professor 
 
Aligarh Muslim University, Aligarh, India
Aligarh - 202 002   
Uttar Pradesh   
 
E-mail: tsartaj62@yahoo.com
Mobile: +91935-825-5791
 
URL: http://members.nanosociety.us/tsartaj62#
 
Area of Specialization:
Cancer Nanotechnology
Research Summary:
Design and Synthesis of Nano Metal based drugs for cancer
 
Publications:
1. Tabassum, S., Khan, R. A., Arjmand, F., Aziz, M., Juvekar, A. S. and Zingde, S. M.  Carbohydrate-conjugate heterobimetallic complexes: synthesis, DNA binding studies, artificial nuclease activity and in vitro cytotoxicity. Carbohydrate Research. 2011.  [PubMed]
2. Arjmand, F., Sharma, G. C., Sayeed, F., Muddassir, M. and Tabassum, S.  De novo design of chiral organotin cancer drug candidates: Validation of enantiopreferential binding to molecular target DNA and 5'-GMP by UV-visible, fluorescence, (1)H and (31)P NMR. Journal of Photochemistry and Photobiology. B, Biology. 2011.  105, 167-174. [PubMed]
3. Arjmand, F., Sharma, G. C., Muddassir, M. and Tabassum, S.  Synthesis and enantiopreferential DNA-binding profile of late 3d transition metal R- and S-enantiomeric complexes derived from N,N-bis-(1-benzyl-2-ethoxyethane): Validation of R-enantiomer of copper(II) complex as a human topoisomerase II inhibitor. Chirality. 2011.  23, 557-567. [PubMed]
4. Tabassum, S., Khan, R. A., Arjmand, F., Juvekar, A. S. and Zingde, S. M.  Synthesis of carbohydrate-conjugate heterobimetallic Cu(II)-Sn(2)(IV) and Zn(II)-Sn(2)(IV) complexes; their interactions with CT DNA and nucleotides; DNA cleavage, in-vitro cytotoxicity. European Journal of Medicinal Chemistry. 2010.  45, 4797-4806. [PubMed]
5. Lupidi, G., Marchetti, F., Masciocchi, N., Reger, D. L., Tabassum, S., Astolfi, P., Damiani, E. and Pettinari, C.  Synthesis, structural and spectroscopic characterization and biomimetic properties of new copper, manganese, zinc complexes: identification of possible superoxide-dismutase mimics bearing hydroxyl radical generating/scavenging abilities. Journal of Inorganic Biochemistry. 2010.  104, 820-830. [PubMed]
6. Tabassum, S., Chandra, S., Arjmand, F. and Azam, A.  DNA interaction studies of new nano metal based anticancer agent: validation by spectroscopic methods. Nanotechnology. 2010.  21, 195102. [PubMed]
7. Tabassum, S. and Bhat, I. U.  Synthesis and characterization of glucose-bis(pyrazole)-Cu(II)/Ni(II) complexes and their in vitro DNA binding studies. Chemical & Pharmaceutical Bulletin. 2010.  58, 318-325. [PubMed]
8. Tabassum, S., Bhat, I. U. and Arjmand, F.  Synthesis of new heterometallic macromolecules: their DNA binding, cleavage activity and in vitro model electrochemotherapy study. Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy. 2009.  74, 1152-1159. [PubMed]
9. Bhat, I. U. and Tabassum, S.  Synthesis of new piperazine derived Cu(II)/Zn(II) metal complexes, their DNA binding studies, electrochemistry and anti-microbial activity: validation for specific recognition of Zn(II) complex to DNA helix by interaction with thymine base. Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy. 2009.  72, 1026-1033. [PubMed]
10. Tak, A. A., Arjmand, F. and Tabassum, S.  Synthesis of New Five Coordinated Copper(II) and Nickel(II) Complexes of L-Valine and Kinetic Study of Copper(II) with Calf Thymus DNA. Metal-based Drugs. 2002.  9, 81-90. [PubMed]
11. Mathur, S. and Tabassum, S.  Template synthesis of novel carboxamide dinuclear copper (II) complex: spectral characterization and reactivity towards calf-thymus DNA. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 2008.  21, 299-310. [PubMed]
12. Shi, Z., Tabassum, S., Jiang, W., Zhang, J., Mathur, S., Wu, J. and Shi, Y.  Identification of a potent inhibitor of human dual-specific phosphatase, VHR, from computer-aided and NMR-based screening to cellular effects. Chembiochem : A European Journal of Chemical Biology. 2007.  8, 2092-2099. [PubMed]
13. Mathur, S. and Tabassum, S.  Synthesis and characterization of a new macrocyclic copper(II) complex with an N-glycosidic pendant arm: in vitro cytotoxicity and binding studies with calf-thymus DNA. Chemistry & Biodiversity. 2006.  3, 312-325. [PubMed]
14. Tabassum, S., Parveen, S. and Arjmand, F.  New modulated metallic macrocycles: Electrochemistry and their interaction with calf thymus DNA. Acta Biomaterialia. 2005.  1, 677-689. [PubMed]
15. Hoti, N., Zhu, D. E., Song, Z., Wu, Z., Tabassum, S. and Wu, M.  p53-dependent apoptotic mechanism of a new designer bimetallic compound tri-phenyl tin benzimidazolethiol copper chloride (TPT-CuCl2): in vivo studies in Wistar rats as well as in vitro studies in human cervical cancer cells. The Journal of Pharmacology and Experimental Therapeutics. 2004.  311, 22-33. [PubMed]
16. Hoti, N., Ma, J., Tabassum, S., Wang, Y. and Wu, M.  Triphenyl tin benzimidazolethiol, a novel antitumor agent, induces mitochondrial-mediated apoptosis in human cervical cancer cells via suppression of HPV-18 encoded E6. Journal of Biochemistry. 2003.  134, 521-528. [PubMed]
 
 
Education 
::
Ph.D.
Member
::
Member of Nanosociety
  Last modified on : Nov 16, 2011
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.