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Biplab Bose, M.Pharm, Ph.D.
Assistant Professor 
 
Indian Institute of Technology
Department of Biotechnology
Guwahati - 781 039   
Assam   
 
E-mail: biplabbose@iitg.ernet.in
Phone: +91-361-2582216
Fax: +91-361-2582249, +91-361-2690762
 
URL: http://iitg.ac.in/biotech/Faculty%20Homepage/B.Bose.htm
 
Positions Held:
Position Affiliation Time Period
Assistant Professor Indian Institute of Technology, Guwahati 2006-Present
Lecturer Birla Institute of Technology & Science Pilani, Rajasthan 2005-2006
 
Area of Specialization:
Immunology
Research Summary:
Development of recombinant therapeutic antibodies against infectious diseases and in cancer immunotherapy
General interest in different theoretical aspects of biological systems.
 
Publications:
1. Bose, B., Khanna, N., Acharya, S. K. and Sinha, S.  Generation and characterization of a single-gene mouse-human chimeric antibody against hepatitis B surface antigen. Journal of Gastroenterology and Hepatology. 2006.  21, 1439-1447. [PubMed]
2. Bose, B., Khanna, N., Acharya, S.K.and Sinha, S. Generation and characterization of a chimeric antibody against Hepatitis B surface antigen. Biotechnology and Applied Biochemistry. 2006. 43(Pt 2):93-101.
3. Bose, B., Khanna, N., Acharya, S. K. and Sinha, S.  High affinity mouse-human chimeric Fab against hepatitis B surface antigen. World Journal of Gastroenterology : WJG. 2005.  11, 7569-7578. [PubMed]
4. Bose, B. and Sinha, S.  Problems in using statistical analysis of replacement and silent mutations in antibody genes for determining antigen-driven affinity selection. Immunology. 2005.  116, 172-183. [PubMed]
5. Bose, B., Chugh, D. A., Kala, M., Acharya, S. K., Khanna, N. and Sinha, S.  Characterization and molecular modeling of a highly stable anti-Hepatitis B surface antigen scFv. Molecular Immunology. 2003.  40, 617-631. [PubMed]
 

 
Book Chapters:
Bose, B., Acharya, S.K., Khanna, N. and Sinha, S. In Chandra P and Kumar B.V.R (eds) Mathematical Biology: Recent trends.Anamaya Publishers, New Delhi, India. 2005. pp - 218-223.
 
Grant Support:
Project Title Role Funding Agency Sanction Number Sanction Date
Combination therapy using suicide genes and recombinant antibody Department of Biotechnology, Government of India 2008-2013
Inhibitor Based Selection of Blocking Antibodies against Heparin-binding EGF-like Growth Factor: Developing Potent Molecules for Antibody-based Cancer Therapy Department of Biotechnology, Government of India 2007-2010
Development of Therapeutic Human Antibodies Against Cripto-1: Targeting Oncogenic Signaling. Department of Science & Technology, Government of India 2007-2010

 
 
 
Education 
::
M.Pharm Jadavpur University, Kolkata, India
::
Ph.D. All India Institute of Medical Sciences, New Delhi, India
Member
::
Member, Indian Immunology Society
::
Member, The Society of Biological Chemists, India
  Last modified on : Mar 4, 2011
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