INCREDB ID : 300
Home >> Investigator Page Previous      Next
Bramanandam Manavathi, Ph.D.
Lecturer 
 
School of Life Sciences, University of Hyderabad
Department of Biochemistry
Central University
Hyderabad - 500 046   
Andhra Pradesh   
 
Phone: +91-40-23134546
Mobile: +91-9490932411
 
URL: http://www.uohyd.info/index.php/academics/schools-of-study/sciences/dept-biochemistry/faculty-biochemistry/bramanandam
 
Positions Held:
Position Affiliation Time Period
Lecturer School of Life Sciences, University of Hyderabad, Hyderabad, India 2007-Present
 
Area of Specialization:
Molecular Biology
Research Summary:
Molecular Mechanisms of Oncogenesis
 
Publications:
1. Nair, B. C., Nair, S. S., Chakravarty, D., Challa, R., Manavathi, B., Yew, P. R., Kumar, R., Tekmal, R. R. and Vadlamudi, R. K.  Cyclin-dependent kinase-mediated phosphorylation plays a critical role in the oncogenic functions of PELP1. Cancer Research. 2010.  70, 7166-7175. [PubMed]
2. Kumar, R., Balasenthil, S., Manavathi, B., Rayala, S. K. and Pakala, S. B.  Metastasis-associated protein 1 and its short form variant stimulates Wnt1 transcription through promoting its derepression from Six3 corepressor. Cancer Research. 2010.  70, 6649-6658. [PubMed]
3. Manavathi, B., Singh, K. and Kumar, R.  MTA family of coregulators in nuclear receptor biology and pathology. Nuclear Receptor Signaling. 2007.  5, e010. [PubMed]
4. Pandey, J. P., Gorla, P., Manavathi, B. and Siddavattam, D.  mRNA secondary structure modulates the translation of organophosphate hydrolase (OPH) in E. coli. Molecular Biology Reports. 2009.  36, 449-454. [PubMed]
5. Manavathi, B., Peng, S., Rayala, S. K., Talukder, A. H., Wang, M. H., Wang, R. A., Balasenthil, S., Agarwal, N., Frishman, L. J. and Kumar, R.  Repression of Six3 by a corepressor regulates rhodopsin expression. Proceedings of the National Academy of Sciences of the United States of America. 2007.  104, 13128-13133. [PubMed]
6. Manavathi, B., Rayala, S. K. and Kumar, R.  Phosphorylation-dependent regulation of stability and transforming potential of ETS transcriptional factor ESE-1 by p21-activated kinase 1. The Journal of Biological Chemistry. 2007.  282, 19820-19830. [PubMed]
7. Manavathi, B. and Kumar, R.  Metastasis tumor antigens, an emerging family of multifaceted master coregulators. The Journal of Biological Chemistry. 2007.  282, 1529-1533. [PubMed]
8. Acconcia, F., Manavathi, B., Mascarenhas, J., Talukder, A. H., Mills, G. and Kumar, R.  An inherent role of integrin-linked kinase-estrogen receptor alpha interaction in cell migration. Cancer Research. 2006.  66, 11030-11038. [PubMed]
9. Verma, A., Wang, H., Manavathi, B., Fok, J. Y., Mann, A. P., Kumar, R. and Mehta, K.  Increased expression of tissue transglutaminase in pancreatic ductal adenocarcinoma and its implications in drug resistance and metastasis. Cancer Research. 2006.  66, 10525-10533. [PubMed]
10. Manavathi, B., Acconcia, F., Rayala, S. K. and Kumar, R.  An inherent role of microtubule network in the action of nuclear receptor. Proceedings of the National Academy of Sciences of the United States of America. 2006.  103, 15981-15986. [PubMed]
11. Mann, A. P., Verma, A., Sethi, G., Manavathi, B., Wang, H., Fok, J. Y., Kunnumakkara, A. B., Kumar, R., Aggarwal, B. B. and Mehta, K.  Overexpression of tissue transglutaminase leads to constitutive activation of nuclear factor-kappaB in cancer cells: delineation of a novel pathway. Cancer Research. 2006.  66, 8788-8795. [PubMed]
12. Rayala, S. K., den, H., Manavathi, B., Talukder, A. H., Song, C., Peng, S., Barnekow, A., Kremerskothen, J. and Kumar, R.  Essential role of KIBRA in co-activator function of dynein light chain 1 in mammalian cells. The Journal of Biological Chemistry. 2006.  281, 19092-19099. [PubMed]
13. Manavathi, B. and Kumar, R.  Steering estrogen signals from the plasma membrane to the nucleus: two sides of the coin. Journal of Cellular Physiology. 2006.  207, 594-604. [PubMed]
14. Vadlamudi, R. K., Manavathi, B., Balasenthil, S., Nair, S. S., Yang, Z., Sahin, A. A. and Kumar, R.  Functional implications of altered subcellular localization of PELP1 in breast cancer cells. Cancer Research. 2005.  65, 7724-7732. [PubMed]
15. Manavathi, B., Nair, S. S., Wang, R. A., Kumar, R. and Vadlamudi, R. K.  Proline-, glutamic acid-, and leucine-rich protein-1 is essential in growth factor regulation of signal transducers and activators of transcription 3 activation. Cancer Research. 2005.  65, 5571-5577. [PubMed]
16. Vadlamudi, R. K., Manavathi, B., Singh, R. R., Nguyen, D., Li, F. and Kumar, R.  An essential role of Pak1 phosphorylation of SHARP in Notch signaling. Oncogene. 2005.  24, 4591-4596. [PubMed]
17. Siddavattam, D., Khajamohiddin, S., Manavathi, B., Pakala, S. B. and Merrick, M.  Transposon-like organization of the plasmid-borne organophosphate degradation (opd) gene cluster found in Flavobacterium sp. Applied and Environmental Microbiology. 2003.  69, 2533-2539. [PubMed]
18. Somara, S., Manavathi, B., Tebbe, C. C. and Siddavatam, D.  Localisation of identical organophosphorus pesticide degrading (opd) genes on genetically dissimilar indigenous plasmids of soil bacteria: PCR amplification, cloning and sequencing of opd gene from Flavobacterium balustinum. Indian Journal of Experimental Biology. 2002.  40, 774-779. [PubMed]
 

 
 
Education 
::
Ph.D. Sri Krishnadevaraya University, Anantapur, India, 1997-2002
::
M.Sc. Sri Krishnadevaraya University, Anantapur, India, 1995-1997
Type of Neoplasms
Breast
Female
  Last modified on : Mar 4, 2011
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.