Harinivas H.  Krishnan,                                
                               
                              Scientist  
                           
                         
                                  
         
                                                    
                                                    
                            Centre for Cellular and Molecular Biology 
                           
                                                                                                        
                            Uppal Road 
                           
                                                    
                            Hyderabad - 500 007                                 
                           
                                                    
                            Andhra Pradesh                                 
                           						  
                                                            
                           
                                                    
                            E-mail: hkrishnan@ccmb.res.in  
                           
                                                                              
                            Phone: +91-40-27192865 
                           
                          
                               
                           
                          
                            URL:   http://www.ccmb.res.in/scientistdetails.php?grpid=30  
                           
                          
                          						  
                              
                           
						  
	                             
                            Positions Held:  
                           
                                                    
                            
                                
                                  Position  
                                  Affiliation  
                                  Time Period   
                                 
                                                                
                                  Scientist  
                                  Center for Cellular and Molecular Biology, Hyderabad, India 
                                  
								  Present 
                                 
                                                            
 
                           
                          
                              
                           
                                                                              
                            Area of Specialization:  
                           
                          
                          
  
     
    Microbiology 
   
     
                          
                        
                           
                           
                         
                         
                                                    
                                                    
                          
                             
                           
                                                    
                            Publications:  
                           
                          
                            
	
		
			
				1. 
			
				Krishnan, H. H. , Sharma-Walia, N., Streblow, D. N., Naranatt, P. P. and Chandran, B.  Focal adhesion kinase is critical for entry of Kaposi's sarcoma-associated herpesvirus into target  cells. Journal of Virology.  2006.  80, 1167-1180. [PubMed]  
		 
		
			
				2. 
			
				Krishnan, H. H. , Sharma-Walia, N., Zeng, L., Gao, S. J. and Chandran, B.  Envelope glycoprotein gB of Kaposi's sarcoma-associated herpesvirus is essential for egress from infected cells. Journal of Virology.  2005.  79, 10952-10967. [PubMed]  
		 
		
			
				3. 
			
				Sharma-Walia, N., Krishnan, H. H. , Naranatt, P. P., Zeng, L., Smith, M. S. and Chandran, B.  ERK1/2 and MEK1/2 induced by Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) early during infection of target  cells are essential for expression of viral genes and for establishment of infection. Journal of Virology.  2005.  79, 10308-10329. [PubMed]  
		 
		
			
				4. 
			
				Naranatt, P. P., Krishnan, H. H. , Smith, M. S. and Chandran, B.  Kaposi's sarcoma-associated herpesvirus modulates microtubule dynamics via RhoA-GTP-diaphanous 2 signaling and utilizes the dynein motors to deliver its DNA to the nucleus. Journal of Virology.  2005.  79, 1191-1206. [PubMed]  
		 
		
			
				5. 
			
				Krishnan, H. H. , Ghosh, A., Paul, K. and Chowdhury, R.  Effect of anaerobiosis on expression of virulence factors in Vibrio cholerae. Infection and Immunity.  2004.  72, 3961-3967. [PubMed]  
		 
		
			
				6. 
			
				Sharma-Walia, N., Naranatt, P. P., Krishnan, H. H. , Zeng, L. and Chandran, B.  Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 envelope glycoprotein gB induces the integrin-dependent focal adhesion kinase-Src-phosphatidylinositol 3-kinase-rho GTPase signal pathways and cytoskeletal rearrangements. Journal of Virology.  2004.  78, 4207-4223. [PubMed]  
		 
		
			
				7. 
			
				Krishnan, H. H. , Naranatt, P. P., Smith, M. S., Zeng, L., Bloomer, C. and Chandran, B.  Concurrent expression of latent and a limited number of lytic genes with immune modulation and antiapoptotic function by Kaposi's sarcoma-associated herpesvirus early during infection of primary endothelial and fibroblast cells and subsequent decline of lytic gene expression. Journal of Virology.  2004.  78, 3601-3620. [PubMed]  
		 
		
			
				8. 
			
				Naranatt, P. P., Krishnan, H. H. , Svojanovsky, S. R., Bloomer, C., Mathur, S. and Chandran, B.  Host gene induction and transcriptional reprogramming in Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8)-infected endothelial, fibroblast, and B cells: insights into modulation events early during infection. Cancer Research.  2004.  64, 72-84. [PubMed]  
		 
		
			
				9. 
			
				Naranatt, P. P., Akula, S. M., Zien, C. A., Krishnan, H. H.  and Chandran, B.  Kaposi's sarcoma-associated herpesvirus induces the phosphatidylinositol 3-kinase-PKC-zeta-MEK-ERK signaling pathway in target  cells early during infection: implications for infectivity. Journal of Virology.  2003.  77, 1524-1539. [PubMed]  
		 
	 
	 
	
	 
	
	
  
                           
                         
                                                    
                            Grant Support:  
                           
                                                    
                            
                                
                                  Project Title  
                                  Role  
                                  Funding Agency   
                                  Sanction Number  
                                  Sanction Date  
                                 
                                                                
                                  Regulation of protein translation during the infection of Kaposi s sarcoma associated herpes virus/ human herpes virus - 8 
                                  Principal Investigator 
                                  Department of Biotechnology, Government of India 
                                  BT/PR13176/GBD/27/210/2009 
                                  
                                  
								  
								  
								  
								  
								  
								  
								  
								  2010-2013								   
                                 
                                                                
                                  Investigating the role of protein translation in HCV associated hepatocellular carcinoma 
                                  Principal Investigator 
                                  Department of Biotechnology, Government of India 
                                  BT/PR11339/MED/29/103/200 8 
                                  
                                  
								  
								  
								  
								  
								  
								  
								  
								  2009-2012								   
                                 
                                                              
                                 
 
                           
                          
                              
                           
                                                
 
                      
                          
                         
                     
                    
                        
                                      Last modified on : Mar 4, 2011