INCREDB ID : 268
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Utpal Sanyal, Ph.D.
Senior Scientific Officer (Senior Assistant Director Grade)  
 
Chittaranjan National Cancer Institute
Anticancer Drug Development
37, S. P. Mukherjee Road
Kolkata - 700 026   
West Bengal   
 
E-mail: utpal.sanyal@cnci.org.in
Phone: +91-33-24765101, Extn.329
Fax: +91-33-4757606
 
URL: http://www.cnci.org.in/research/research_main.html
 
Positions Held:
Position Affiliation Time Period
Senior Scientific Officer (Senior Assistant Director Grade) Chittaranjan National Cancer Institute, Kolkata, India 1989-Present
 
Area of Specialization:
Pharmacology
Oncology
Research Summary:
Synthesis of new rationally designed anticancer compounds
In vivo and in vitro anti-tumoral screening of the anticancer compounds
 
Publications:
1. Mukherjee, A., Dutta, S., Shanmugavel, M., Mondhe, D. M., Sharma, P. R., Singh, S. K., Saxena, A. K. and Sanyal, U.  6-Nitro-2-(3-hydroxypropyl)-1H-benz[de]isoquinoline-1,3-dione, a potent antitumor agent, induces cell cycle arrest and apoptosis. Journal of Experimental & Clinical Cancer Research : CR. 2010.  29, 175. [PubMed]
2. Mukherjee, A., Hazra, S., Dutta, S., Muthiah, S., Mondhe, D. M., Sharma, P. R., Singh, S. K., Saxena, A. K., Qazi, G. N. and Sanyal, U.  Antitumor efficacy and apoptotic activity of substituted chloroalkyl 1H-benz[de]isoquinoline-1,3-diones: a new class of potential antineoplastic agents. Investigational New Drugs. 2010.  [PubMed]
3. Goswami, S., Bose, A., Sarkar, K., Roy, S., Chakraborty, T., Sanyal, U. and Baral, R.  Neem leaf glycoprotein matures myeloid derived dendritic cells and optimizes anti-tumor T cell functions. Vaccine. 2010.  28, 1241-1252. [PubMed]
4. Mukherjee, A., Dutta, S., Chashoo, G., Bhagat, M., Saxena, A. K. and Sanyal, U.  Evaluation of fluoren-NU as a novel antitumor agent. Oncology Research. 2009.  17, 387-396. [PubMed]
5. Mukherjee, A., Dutta, S. and Sanyal, U.  Evaluation of dimethoxydop-NU as a novel anti-tumor agent. Journal of Experimental & Clinical Cancer Research : CR. 2007.  26, 489-497. [PubMed]
6. Pain, A., Samanta, S., Dutta, S., Saxena, A. K., Shanmugavel, M., Sharma, M., Qazi, G. N. and Sanyal, U.  Synthesis and evaluation of ethylnitrosoureas of substituted naphthalimides as anticancer compounds. Acta Poloniae Pharmaceutica. 2007.  64, 27-33. [PubMed]
7. Samanta, S., Pain, A., Dutta, S., Saxena, A. K., Shanmugavel, M., Pandita, R. M., Qazi, G. N. and Sanyal, U.  Antitumor activity of Nitronaphthal-NU, a novel mixed-function agent. Journal of Experimental Therapeutics & Oncology. 2005.  5, 15-22. [PubMed]
8. Samanta, S., Pain, A., Ghosh, M., Dutta, S. and Sanyal, U.  Evaluation of fluorenhymustine as a rationally designed novel anticancer agent. Experimental Oncology. 2005.  27, 279-285. [PubMed]
9. Pain, A., Samanta, S., Dutta, S., Saxena, A. K., Shanmugavel, M., Kampasi, H., Quazi, G. N. and Sanyal, U.  Synthesis and evaluation of substituted naphthalimide nitrogen mustards as rationally designed anticancer compounds. Acta Poloniae Pharmaceutica. 2003.  60, 285-291. [PubMed]
10. Sanyal U.  Stamping out cancer. British Journal of Cancer. 2003.  89, 2165-2171. [PubMed]
11. Sanyal, U., Bhattacharyya, S., Patra, A. and Hazra, B.  Liquid chromatographic separation of derivatives of diospyrin, a bioactive bisnaphthoquinonoid plant-product, and analogous naphthyl compounds. Journal of Chromatography. A. 2003.  1017, 225-232. [PubMed]
12. Pain, A., Samanta, S., Dutta, S., Saxena, A. K., Shanmugavel, M., Kampasi, H., Qazi, G. N. and Sanyal, U.  Evaluation of naphthalmustine, a nitrogen mustard derivative of naphthalimide as a rationally-designed anticancer agent. Journal of Experimental & Clinical Cancer Research : CR. 2003.  22, 411-418. [PubMed]
13. Samanta, S., Pain, A., Dutta, S. and Sanyal, U.  Evaluation of naphthal-NU, a 2-chloroethylnitrosourea derivative of naphthalimide, as a mixed-function anticancer agent. Journal of Experimental & Clinical Cancer Research : CR. 2002.  21, 87-93. [PubMed]
14. Ganguly, C., Dutta, K., Sanyal, U., Roy, C., Basu, P. S. and Das, S.  Response of Cervical Intra-epithelial Lesions to Vitamin E Supplementation - A Preliminary Report. Asian Pacific Journal of Cancer Prevention : APJCP. 2001.  2, 305-308. [PubMed]
15. Samanta, S., Pain, A., Dutta, S. and Sanyal, U.  Synthesis and evaluation of 2-chloroethylnitrosoureas of substituted naphthalimides as mixed-function anticancer compounds. Acta Poloniae Pharmaceutica. 2001.  58, 351-356. [PubMed]
16. Ray, S., Chattopadhyay, N., Sanyal, U., Biswas, N. and Chatterjee, A.  Integrin modulating factor: a 30-kD protein that modulates the expression and function of alpha5beta1 integrin receptor. Journal of Environmental Pathology, Toxicology and Oncology. 2001.  20, 199-209. [PubMed]
17. Sanyal, U., Nanda, R., Samanta, S., Pain, A., Dutta, S., Verma, A. S., Rider, B. J. and Agrawal, K. C.  Evaluation of dimethylaminosulfonates of alkane diols as a novel group of anticancer agents. Cancer Letters. 2000.  155, 89-97. [PubMed]
18. Ghosh, M., Dutta, S. and Sanyal, U.  Evaluation of 2-(methylaminosulfonyl)-1-(arylsulfonyl)hydrazines as anticancer agents. Neoplasma. 1999.  46, 242-245. [PubMed]
19. Ghosh, M., Sadhu, U., Bhattacharya, S., Dutta, S., Bhattacharya, B. and Sanyal, U.  Evaluation of toxicity of beta-tethymustine, a new anticancer compound, in mice. Cancer Letters. 1999.  138, 107-114. [PubMed]
20. Ghosh, M., Bhattacharya, S., Sadhu, U., Dutta, S. and Sanyal, U.  Evaluation of beta-tethymustine, a new anticancer compound, in murine tumour models. Cancer Letters. 1997.  119, 7-12. [PubMed]
21. Bhattacharya, S., Ghosh, M., Sadhu, U., Dutta, S. and Sanyal, U.  Evaluation of phthalmustine, a new anticancer compound. II. Tumor inhibitory effect in murine Ehrlich ascites carcinoma and sarcoma-180. Neoplasma. 1996.  43, 209-213. [PubMed]
22. Pal, S., Sanyal, U. and Chattopadhyay, U.  Purification and characterization of a new 85-kDa glycoprotein antigen from human breast tumor. International Journal of Cancer.  1995.  60, 759-765. [PubMed]
23. Sanyal, U., Dutta, S. and Das, H.  Evaluation of the anticancer property of a new alpha-methylene-gamma-lactone derivative of phthalimide. Neoplasma. 1995.  42, 129-132. [PubMed]
24. Sadhu, U., Ghosh, M., Bhattacharya, S., Dutta, S., Das, H. and Sanyal, U.  Evaluation of toxicity of cypenhymustine, a new anticancer compound, in mice. Cancer Letters. 1994.  85, 65-72. [PubMed]
25. Mukhopadhyay, P., Gupta, J. D., Sanyal, U., Das, S. and Senyal, U.  Influence of dietary restriction and soyabean supplementation on the growth of a murine lymphoma and host immune function. Cancer Letters. 1994.  78, 151-157. [PubMed]
26. Bhattacharya, S., Ganguly, C., Sanyal, U. and Das, S.  Evaluation of phthalmustine, a new anticancer compound. I. Effect on Dalton's ascitic lymphoma in mice. Neoplasma. 1994.  41, 35-38. [PubMed]
27. Sanyal, U., Bhattacharya, S., Sadhu, U., Dutta, S., Das, H. and Ghosh, M.  Evaluation of 'cypenhymustine', a new anticancer compound, in murine tumour models. Cancer Letters. 1993.  70, 1-6. [PubMed]
28. Dasgupta, J., Sanyal, U. and Das, S.  Vitamin E--its status and role in leukemia and lymphoma. Neoplasma. 1993.  40, 235-240. [PubMed]
29. Sanyal, U., De, R., Dutta, S., Das, H. and Ghost, M.  Evaluation of 2-(methylaminosulfonyl)-1-(arylsulfonyl)-1-methylhydrazines as anticancer agents. Neoplasma. 1993.  40, 219-222. [PubMed]
30. Panda, C. K., Choudhury, K., Sanyal, U. and Chakraborti, S. K.  Mechanism of action of alpha-methylene-gamma-lactone derivatives of substituted nucleic acid bases in tumour cells. Chemotherapy. 1989.  35, 174-180. [PubMed]
31. Sanyal, U., Mitra, S., Pal, P. and Chakraborti, S. K.  New alpha-methylene gamma-lactone derivatives of substituted nucleic acid bases as potential anticancer agents. Journal of Medicinal Chemistry. 1986.  29, 595-599. [PubMed]
32. Sanyal, U., Chatterjee, R. S., Das, S. K. and Chakraborti, S. K.  Alkylphosphonium salts as a new class of antitumor agents. Neoplasma. 1984.  31, 149-155. [PubMed]
33. Pal, P., Sanyal, U. and Chakraborti, S. K.  New arylsulfonylhydrazones of substituted benzaldehydes as anticancer agents. Neoplasma. 1983.  30, 551-556. [PubMed]

 

 

 
Grant Support:
Project Title Role Funding Agency Sanction Number Sanction Date
Tobacco Cessation Center (TCC) project Co-PI Ministry of Health & Family Welfare, Government of India

 
 
 
Education 
::
M.Sc. in Organic Chemistry
::
Ph.D. Calcutta University, India
Honors and Awards
::
1997, International ICRETT Fellowship of UICC, Switzerland
::
1967, National Science Talent Search Scholarship, Government of India
Member
::
Association of UICC Fellows, UICC
::
Indian Association for Cancer Research
::
Indian Chemical Society
::
Indian Association for Cultivation of Science
::
New York Academy of Sciences
  Last modified on : Mar 4, 2011
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.