Home >> Investigator Page Previous      Next
Krishna P. Gupta, Ph.D.
Scientist F 
Indian Institute of Toxicology Research
Carcinogenesis Division
Post Box No. 80, Mahatma Gandhi Marg
Lucknow - 226 001   
Uttar Pradesh   
Phone: +91-522-2627586 Extn. 313
Fax: +91-522-2628227, +91-522-2611547
Positions Held:
Position Affiliation Time Period
Scientist F Indian Institute of Toxicology Research, Lucknow, India Present
Area of Specialization:
Molecular Biology
Research Summary:
Evaluation of tumorigenenic potential and mechanisms of toxic chemicals in laboratory animals using single/multistage models
Mitigation of tumor development and its mechanisms by the use of naturally occurring compounds
Status and modulation of the gene expression at different stages of tumor development
Genetic susceptibility to cancer development
Genetic and epigenetic modifications of genes and its use in the cancer detection and cancer control
1. Pandey, M. and Gupta, K. P.  Epigenetics, an early event in the modulation of gene expression by inositol hexaphosphate in ethylnitrosourea exposed mouse lungs. Nutrition and Cancer. 2011.  63, 89-99. [PubMed]
2. Singh, J. and Gupta, K. P.  Inositol hexaphosphate induces apoptosis by coordinative modulation of P53, Bcl-2 and sequential activation of caspases in 7,12 dimethylbenz[a]anthracene exposed mouse epidermis. Journal of Environmental Pathology, Toxicology and Oncology. 2008.  27, 209-217. [PubMed]
3. Singh, J. and Gupta, K. P.  Induction of apoptosis by calcium D-glucarate in 7,12-dimethyl benz [a] anthracene-exposed mouse skin. Journal of Environmental Pathology, Toxicology and Oncology . 2007.  26, 63-73. [PubMed]
4. Gupta, K. P. and Singh, J.  Modulation of carcinogen metabolism and DNA interaction by calcium glucarate in mouse skin. Toxicological Sciences. 2004.  79, 47-55. [PubMed]
5. Gupta, K. P., Singh, J. and Bharathi, R.  Suppression of DMBA-induced mouse skin tumor development by inositol hexaphosphate and its mode of action. Nutrition and Cancer. 2003.  46, 66-72. [PubMed]
6. Singh, J. and Gupta, K. P.  Calcium glucarate prevents tumor formation in mouse skin. Biomedical and Environmental Sciences . 2003.  16, 9-16. [PubMed]


  Last modified on : Mar 4, 2011
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.