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Soumitra Kumar Choudhuri, Ph.D.
Senior Scientific Officer 
Chittaranjan National Cancer Institute
In-vitro Carcinogeneis and Cellular chemotherapy
37, S. P. Mukherjee Road
Kolkata - 700 026   
West Bengal   
E-mail: soumitrakumar.coudhuri
Phone: +91-33-24765101, Extn.402
Fax: +91-33-4757606
Positions Held:
Position Affiliation Time Period
Senior Scientific Officer Chittaranjan National Cancer Institute, Kolkata, India Present
Area of Specialization:
Research Summary:
To develop novel resistance modifying agent capable of overcoming drug resistance in human
1. Ganguly, A., Basu, S., Chakraborty, P., Chatterjee, S., Sarkar, A., Chatterjee, M. and Choudhuri, S. K.  Targeting mitochondrial cell death pathway to overcome drug resistance with a newly developed iron chelate. PloS One. 2010.  5, e11253. [PubMed]
2. Chatterjee, S., Mookerjee, A., Basu, J. M., Chakraborty, P., Ganguly, A., Adhikary, A., Mukhopadhyay, D., Ganguli, S., Banerjee, R., Ashraf, M., Biswas, J., Das, P. K., Sa, G., Chatterjee, M., Das, T. and Choudhuri, S. K.  A novel copper chelate modulates tumor associated macrophages to promote anti-tumor response of T cells. PloS One. 2009.  4, e7048. [PubMed]
3. Basu, S., Majumder, S., Chatterjee, S., Ganguly, A., Efferth, T. and Choudhuri, S. K.  Detection and characterization of a glutathione conjugate of a novel copper complex. In Vivo. 2009.  23, 401-408. [PubMed]
4. Majumder, S., Chatterjee, S., Pal, S., Biswas, J., Efferth, T. and Choudhuri, S. K.  The role of copper in drug-resistant murine and human tumors. Biometals. 2009.  22, 377-384. [PubMed]
5. Mookerjee, B., Mookerjee, A., Banerjee, R., Saha, M., Singh, S., Naskar, K., Tripathy, G., Sinha, P. K., Pandey, K., Sundar, S., Bimal, S., Das, P. K., Choudhuri, S. K. and Roy, S.  Inhibition of ABC transporters abolishes antimony resistance in Leishmania Infection. Antimicrobial Agents and Chemotherapy. 2008.  52, 1080-1093. [PubMed]
6. Sarkar, K., Bose, A., Laskar, S., Choudhuri, S. K., Dey, S., Roychowdhury, P. K. and Baral, R.  Antibody response against neem leaf preparation recognizes carcinoembryonic antigen. International Immunopharmacology. 2007.  7, 306-312. [PubMed]
7. Mookerjee, A., Basu, J. M., Majumder, S., Chatterjee, S., Panda, G. S., Dutta, P., Pal, S., Mukherjee, P., Efferth, T., Roy, S. and Choudhuri, S. K.  A novel copper complex induces ROS generation in doxorubicin resistant Ehrlich ascitis carcinoma cells and increases activity of antioxidant enzymes in vital organs in vivo. BMC Cancer. 2006.  6, 267. [PubMed]
8. Mookerjee, A., Mookerjee, B., Dutta, P., Majumder, S., Bhattacharyya, S., Biswas, J., Pal, S., Mukherjee, P., Raha, S., Baral, R. N., Das, T., Efferth, T., Sa, G., Roy, S. and Choudhuri, S. K.  Overcoming drug-resistant cancer by a newly developed copper chelate through host-protective cytokine-mediated apoptosis. Clinical Cancer Research. 2006.  12, 4339-4349. [PubMed]
9. Majumder, S., Dutta, P. and Choudhuri, S. K.  The role of copper in development of drug resistance in murine carcinoma. Medicinal Chemistry. 2005.  1, 563-573. [PubMed]
10. Mookerjee, B., Mookerjee, A., Sen, P., Bhaumik, S., Sen, P., Banerjee, S., Naskar, K., Choudhuri, S. K., Saha, B., Raha, S. and Roy, S.  Sodium antimony gluconate induces generation of reactive oxygen species and nitric oxide via phosphoinositide 3-kinase and mitogen-activated protein kinase activation in Leishmania donovani-infected macrophages. Antimicrobial Agents and Chemotherapy. 2006.  50, 1788-1797. [PubMed]
11. Panda, G. S., Bhattacharya, R. K. and Choudhuri, S. K.  Metabolic transformation and mechanism of action of mononitroso caffeidine- a new interpretation. Endocrine, Metabolic & Immune Disorders Drug Targets. 2006.  6, 1-6. [PubMed]
12. Majumder, S., Dutta, P., Mukherjee, P., Datta, E. R., Efferth, T., Bhattacharya, S. and Choudhuri, S. K.  Reversal of drug resistance in P-glycoprotein-expressing T-cell acute lymphoblastic CEM leukemia cells by copper N-(2-hydroxy acetophenone) glycinate and oxalyl bis (N-phenyl) hydroxamic acid. Cancer Letters. 2006.  244, 16-23. [PubMed]
13. Majumder, S., Dutta, P., Mookerjee, A. and Choudhuri, S. K.  The role of a novel copper complex in overcoming doxorubicin resistance in Ehrlich ascites carcinoma cells in vivo. Chemico-biological Interactions. 2006.  159, 90-103. [PubMed]
14. Choudhuri, S. K. and Majumder, S.  Modulation of doxorubicin sensitivity by a novel organic compound, oxalyl bis (N-phenyl) hydroxamic acid on acetyl aminofluorene-induced preneoplastic hepatocytes. Cancer Letters. 2003.  202, 25-34. [PubMed]
15. Choudhuri S. K.  Deactivation of P-glycoprotein by a novel compound, oxalyl bis (N-phenyl) hydroxamic acid. Neoplasma. 2002.  49, 272-277. [PubMed]
16. Chatterjee, A., Biswas, N., Choudhuri, S. K., Mazumder, J. and Chowdhury, J. R.  Identification of a 60-kD antigen associated with malignant growth of human breast tissue. Oncology. 1996.  53, 422-425.
17. Choudhuri, S. K., Das, D., Chatterjee, R. and Chowdhury, J. R.  Antitumor activity of some organotin complexes of hydroxamic acids derived from dibasic carboxylic acid. Chemotherapy. 1991.  37, 122-127. [PubMed]
18. Mookerjee, A., Dutta, P., Majumder, S., Baral, R.N., Choudhuri, S. K. Regulation of multidrug resistance cancer with a novel metal complex. Indian Journal of Medical Research. 2005. 121, 160-161.
19. Bose, A., Ghose, D., Pal, S., Chouhduri, S.K., Baral, R.N. Neem leaf preparation enhances in vitro cytotoxic efficacy of peripheral blood monuclear cells from head and neck squamous cell carcinoma patients by modulating cytokine cytokine signaling pathway. Indian Journal of Medical Research. 2005. 121, 60-67


  Last modified on : Mar 4, 2011
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