INCREDB ID : 234
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Madhumita Roy, Ph.D.
Senior Scientific Officer 
 
Chittaranjan National Cancer Institute
Environmental Carcinogenesis and Toxicology
37, S. P. Mukherjee Road
Kolkata - 700 026   
West Bengal   
 
E-mail: madhumita.roy@cnci.org.in
Phone: +91-33-24765101, Extn.317
Fax: +91-33-4757606
 
URL: http://www.cnci.org.in/research/research_main.html#
 
Positions Held:
Position Affiliation Time Period
Senior Scientific Officer Chittaranjan National Cancer Institute, Kolkata, India Present
 
Area of Specialization:
Oncology
Publications:
1. Biswas, J., Roy, S., Mukherjee, S., Sinha, D. and Roy, M.  Indian spice curcumin may be an effective strategy to combat the genotoxicity of arsenic in Swiss albino mice. Asian Pacific Journal of Cancer Prevention . 2010.  11, 239-247. [PubMed]
2. Mukherjee, S., Bhattacharya, R. K. and Roy, M.  Targeting protein kinase C (PKC) and telomerase by phenethyl isothiocyanate (PEITC) sensitizes PC-3 cells towards chemotherapeutic drug-induced apoptosis. Journal of Environmental Pathology, Toxicology and Oncology. 2009.  28, 269-282. [PubMed]
3. Sinha, D., Roy, S. and Roy, M.  Antioxidant potential of tea reduces arsenite induced oxidative stress in Swiss albino mice. Food and Chemical Toxicology. 2010.  48, 1032-1039. [PubMed]
4. Biswas, J., Sinha, D., Mukherjee, S., Roy, S., Siddiqi, M. and Roy, M.  Curcumin protects DNA damage in a chronically arsenic-exposed population of West Bengal. Human & Experimental Toxicology. 2010.  29, 513-524. [PubMed]
5. Mukherjee, S., Dey, S., Bhattacharya, R. K. and Roy, M.  Isothiocyanates sensitize the effect of chemotherapeutic drugs via modulation of protein kinase C and telomerase in cervical cancer cells. Molecular and Cellular Biochemistry. 2009.  330, 9-22. [PubMed]
6. Sen, T., Moulik, S., Dutta, A., Choudhury, P. R., Banerji, A., Das, S., Roy, M. and Chatterjee, A.  Multifunctional effect of epigallocatechin-3-gallate (EGCG) in downregulation of gelatinase-A (MMP-2) in human breast cancer cell line MCF-7. Life Sciences. 2009.  84, 194-204. [PubMed]
7. Roy, M., Sinha, D., Mukherjee, S., Paul, S. and Bhattacharya, R. K.  Protective effect of dietary phytochemicals against arsenite induced genotoxicity in mammalian V79 cells. Indian Journal of Experimental Biology. 2008.  46, 690-697. [PubMed]
8. Mukherjee, S., Roy, M., Dey, S. and Bhattacharya, R. K.  A Mechanistic Approach for Modulation of Arsenic Toxicity in Human Lymphocytes by Curcumin, an Active Constituent of Medicinal Herb Curcuma longa Linn. Journal of Clinical Biochemistry and Nutrition. 2007.  41, 32-42. [PubMed]
9. Sinha, D., Dey, S., Bhattacharya, R. K. and Roy, M.  In vitro mitigation of arsenic toxicity by tea polyphenols in human lymphocytes. Journal of Environmental Pathology, Toxicology and Oncology. 2007.  26, 207-220. [PubMed]
10. Mukherjee, N. e. e., Ghosh, U., Bhattacharyya, N. P., Bhattacharya, R. K., Dey, S. and Roy, M.  Curcumin-induced apoptosis in human leukemia cell HL-60 is associated with inhibition of telomerase activity. Molecular and Cellular Biochemistry. 2007.  297, 31-39. [PubMed]
11. Chakraborty, S., Ghosh, U., Bhattacharyya, N. P., Bhattacharya, R. K. and Roy, M.  Inhibition of telomerase activity and induction of apoptosis by curcumin in K-562 cells. Mutation Research. 2006.  596, 81-90. [PubMed]
12. Kundu, T., Dey, S., Roy, M., Siddiqi, M. and Bhattacharya, R. K.  Induction of apoptosis in human leukemia cells by black tea and its polyphenol theaflavin. Cancer Letters. 2005.  230, 111-121. [PubMed]
13. Sinha, D., Bhattacharya, R. K., Siddiqi, M. and Roy, M.  Amelioration of sodium arsenite-induced clastogenicity by tea extracts in Chinese hamster v79 cells. Journal of Environmental Pathology, Toxicology and Oncology. 2005.  24, 129-140. [PubMed]
14. Kundu, T., Bhattacharya, R. K., Siddiqi, M. and Roy, M.  Correlation of apoptosis with comet formation induced by tea polyphenols in human leukemia cells. Journal of Environmental Pathology, Toxicology and Oncology. 2005.  24, 115-128. [PubMed]
15. Sinha, D., Roy, M., Siddiqi, M. and Bhattacharya, R. K.  Arsenic-induced micronuclei formation in mammalian cells and its counteraction by tea. Journal of Environmental Pathology, Toxicology and Oncology. 2005.  24, 45-56. [PubMed]
16. Chakraborty, S., Roy, M., Taraphdar, A. K. and Bhattacharya, R. K.  Cytotoxic effect of root extract of Tiliacora racemosa and oil of Semecarpus anacardium nut in human tumour cells. Phytotherapy Research : PTR. 2004.  18, 595-600. [PubMed]
17. Chakraborty, S., Roy, M. and Bhattacharya, R. K.  Prevention and repair of DNA damage by selected phytochemicals as measured by single cell gel electrophoresis. Journal of Environmental Pathology, Toxicology and Oncology. 2004.  23, 215-226. [PubMed]
18. Sinha, D., Roy, M., Dey, S., Siddiqi, M. and Bhattacharya, R. K.  Modulation of arsenic induced cytotoxicity by tea. Asian Pacific Journal of Cancer Prevention : APJCP. 2003.  4, 233-237. [PubMed]
19. Roy, M., Siddiqi, M. and Bhattacharya, R. K.  Cancer Chemoprevention: Tea Polyphenol Induced Cellular and Molecular Responses. Asian Pacific Journal of Cancer Prevention. 2001.  2, 109-116. [PubMed]
20. Roy, M., Chakraborty, S., Siddiqi, M. and Bhattacharya, R. K.  Induction of Apoptosis in Tumor Cells by Natural Phenolic Compounds. Asian Pacific Journal of Cancer Prevention.  2002.  3, 61-67. [PubMed]
21. Roy, M., Chakrabarty, S., Sinha, D., Bhattacharya, R. K. and Siddiqi, M.  Anticlastogenic, antigenotoxic and apoptotic activity of epigallocatechin gallate: a green tea polyphenol. Mutation Research. 2003.  523-524, 33-41. [PubMed]
22. Chakrabarty, S., Roy, M., Hazra, B. and Bhattacharya, R. K.  Induction of apoptosis in human cancer cell lines by diospyrin, a plant-derived bisnaphthoquinonoid, and its synthetic derivatives. Cancer Letters. 2002.  188, 85-93. [PubMed]
 

 
Grant Support:
Project Title Role Funding Agency Sanction Number Sanction Date
Role of curcumin in protecting DNA damage in lymphocytes from human population chronically exposed to arsenic in West Bengal Department of Biotechnology, Government of India
Role of tea in mitigating arsenic toxicity – a detailed mechanistic study in Swiss albino mice Indian Council of Medical Research, Goverment of India
Role of histone deacetylase inhibitors of natural origin towards sensitization of tumor cells via modulation of p53, p21 waf1/cip1 and c-myc Department of Biotechnology, Government of India
Role of tea as supplement with conventional protocols by modulation of tumor markers in leukemic cells: in cultured as well as human cohort National Tea Research Foundation, India

 
 
 
Education 
::
M.Sc.
::
Ph.D.
  Last modified on : Mar 4, 2011
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.