Pritha Ray, Ph.D.
Scientific Officer E
Advanced Centre for Treatment Research and Education in Cancer
Ray Lab
Khanolkar Shodhika 338, Tata Memorial Centre, Kharghar
Navi Mumbai - 410 210
Maharashtra
E-mail: pray@actrec.gov.in
Phone: +91-22-27405000, Extn. 5439
URL: http://www.actrec.gov.in/pi-webpages/PrithaRay/pritha-index.html
Positions Held:
Position
Affiliation
Time Period
Scientific Officer E
Advanced Centre for Treatment, Research and Education in Cancer, Navi Mumbai, India
Present
Principal Investigator
Advanced Centre for Treatment, Research and Education in Cancer, Navi Mumbai, India
2009
Area of Specialization:
Molecular Biology
Publications:
1.
De, A., Ray, P. , Loening, A. M. and Gambhir, S. S. BRET3: a red-shifted bioluminescence resonance energy transfer (BRET)-based integrated platform for imaging protein-protein interactions from single live cells and living animals. The FASEB Journal. 2009. 23, 2702-2709. [PubMed]
2.
Lee, S. W., Padmanabhan, P., Ray, P. , Gambhir, S. S., Doyle, T., Contag, C., Goodman, S. B. and Biswal, S. Stem cell-mediated accelerated bone healing observed with in vivo molecular and small animal imaging technologies in a model of skeletal injury. Journal of Orthopaedic Research. 2009. 27, 295-302. [PubMed]
3.
Ray, P. , De, A., Patel, M. and Gambhir, S. S. Monitoring caspase-3 activation with a multimodality imaging sensor in living subjects. Clinical Cancer Research. 2008. 14, 5801-5809. [PubMed]
4.
Lutz, A. M., Willmann, J. K., Cochran, F. V., Ray, P. and Gambhir, S. S. Cancer screening: a mathematical model relating secreted blood biomarker levels to tumor sizes. PLoS Medicine. 2008. 5, e170. [PubMed]
5.
Ray, P. and Yaghoubi, S. S. CD147: a potential regulator of oncogenesis non-invasive imaging of CD147 in living subjects. Cancer Biology & Therapy. 2008. 7, 1071-1072. [PubMed]
6.
Chin, F. T., Namavari, M., Levi, J., Subbarayan, M., Ray, P. , Chen, X. and Gambhir, S. S. Semiautomated radiosynthesis and biological evaluation of [18F]FEAU: a novel PET imaging agent for HSV1-tk/sr39tk reporter gene expression. Molecular Imaging and Biology. 2008. 10, 82-91. [PubMed]
7.
Ray, P. , Tsien, R. and Gambhir, S. S. Construction and validation of improved triple fusion reporter gene vectors for molecular imaging of living subjects. Cancer Research. 2007. 67, 3085-3093. [PubMed]
8.
Massoud, T. F., Paulmurugan, R., De, A., Ray, P. and Gambhir, S. S. Reporter gene imaging of protein-protein interactions in living subjects. Current Opinion in Biotechnology. 2007. 18, 31-37. [PubMed]
9.
Cao, F., Lin, S., Xie, X., Ray, P. , Patel, M., Zhang, X., Drukker, M., Dylla, S. J., Connolly, A. J., Chen, X., Weissman, I. L., Gambhir, S. S. and Wu, J. C. In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery. Circulation. 2006. 113, 1005-1014. [PubMed]
10.
Padmanabhan, P., Otero, J., Ray, P. , Paulmurugan, R., Hoffman, A. R., Gambhir, S. S., Biswal, S. and Ulaner, G. A. Visualization of telomerase reverse transcriptase (hTERT) promoter activity using a trimodality fusion reporter construct. Journal of Nuclear Medicine. 2006. 47, 270-277. [PubMed]
11.
Shu, C. J., Guo, S., Kim, Y. J., Shelly, S. M., Nijagal, A., Ray, P. , Gambhir, S. S., Radu, C. G. and Witte, O. N. Visualization of a primary anti-tumor immune response by positron emission tomography. Proceedings of the National Academy of Sciences of the United States of America. 2005. 102, 17412-17417. [PubMed]
12.
Paulmurugan, R., Ray, P. , De, A., Chan, C. T. and Gambhir, S. S. Imaging protein–protein interactions in living subjects. Trends in Analytical Chemistry . 2005. 24, 446-458.
13.
Kim, Y. J., Dubey, P., Ray, P. , Gambhir, S. S. and Witte, O. N. Multimodality imaging of lymphocytic migration using lentiviral-based transduction of a tri-fusion reporter gene. Molecular Imaging and Biology. 2004. 6, 331-340. [PubMed]
14.
Ray, P. , De, A., Min, J. J., Tsien, R. Y. and Gambhir, S. S. Imaging tri-fusion multimodality reporter gene expression in living subjects. Cancer Research. 2004. 64, 1323-1330. [PubMed]
15.
Ray, P. , Wu, A. M. and Gambhir, S. S. Optical bioluminescence and positron emission tomography imaging of a novel fusion reporter gene in tumor xenografts of living mice. Cancer Research. 2003. 63, 1160-1165. [PubMed]
16.
Radha, V., Sudhakar, C. h., Ray, P. and Swarup, G. Induction of cytochrome c release and apoptosis by Hck-SH3 domain-mediated signalling requires caspase-3. Apoptosis : An International Journal On Programmed Cell Death. 2002. 7, 195-207. [PubMed]
17.
Ray, P. , Pimenta, H., Paulmurugan, R., Berger, F., Phelps, M. E., Iyer, M. and Gambhir, S. S. Noninvasive quantitative imaging of protein-protein interactions in living subjects. Proceedings of the National Academy of Sciences of the United States of America. 2002. 99, 3105-3110. [PubMed]
18.
Ray, P. , Bauer, E., Iyer, M., Barrio, J. R., Satyamurthy, N., Phelps, M. E., Herschman, H. R. and Gambhir, S. S. Monitoring gene therapy with reporter ge.ne imaging. Seminars in Nuclear Medicine. 2001. 31, 312-320. [PubMed]
19.
Lakhotia, S. C., Ray, P. , Rajendra, T. K. and Prasanth, K. V. The non-coding transcripts of hsr-omega gene in Drosophila: do they regulate trafficking and availability of nuclear-processing factors? Current Science . 1999. 77, 553-563.
20.
Ray, P. , Gangadharan, S., Chattopadhaya, M., Bashamboo, A., Vatnagar, S., Malik, P. and Ali, S. A bubaline derived satellite DNA probe uncovers generic affinities of gaur with other bovids. Journal of Biosciences . 1999. 24, 101-105.
21.
Ray, P. and Lakhotia, S. C. Interaction of the non-protein coding developmental and stress-inducible hsr-w gene with Ras genes of Drosophila melanogaster. Journal of Biosciences . 1998. 23, 377-386.
22.
Lakhotia, S. C. and Ray, P. Hsp83 mutation is a dominant enhancer of lethality associated with absence of non-protein coding hsr-omega locus of D. melanogaster. Journal of Biosciences . 1995. 21, 207-209.
Book Chapters:
Ray, P. and Gambhir, S.S. Non invasive imaging of molecular events with bioluminescent reporter genes in living subjects. In: Reporter Genes - A Practical Guide, Anson, D.S. Editor. Humana Press, Totowa, New Jersey, USA. 2007. Volume 411. pp 131-144.
Ray, P. Illustrating molecular events with light: A perspective on optical reporter genes. In: Optical Imaging of Cancer - Clinical Applications. Rosenthal, E. and Zinn, K.R. Eds., Springer, New York, USA. 2009. Part 2. pp 139-160.
Ray, P. and Gambhir, S.S. Multimodality imaging of reporter genes. In: Molecular Imaging with Reporter Genes. Cambridge University Press, New York, USA. 2010. pp 113-126.
Education
::
Ph.D. in Zoology,
Banaras Hindu University, Varanasi, Uttar Pradesh, India
Honors and Awards
::
Best poster award at XIX All India Cell Biology Conference, IICB, Calcutta
::
Travel award for best poster presentation at Society for Molecular Imaging, St. Louis, USA
::
Travel award for best poster presentation at Academy of Molecular Imaging, Orlando, Florida, USA
Member
::
Reviewer - Journal of Nuclear Medicine, Institute for Laboratory Animal Research Journal and Journal of Bioscience
Type of Neoplasms
Female genital system
Ovaries