Surendra Bathula Reddy, Ph.D.
Scientist C
Central Drug Research Institute
Pharmaceutics Division
Chattar Manzil Palace, M.G. Marg
Lucknow - 226 001
Uttar Pradesh
E-mail: bsreddy@cdri.res.in
Phone: +91-522-2612411-18 Extn. 4302
Fax: +91-522-2623405
URL: http://cdriindia.org/bsreddy.htm
Positions Held:
Position
Affiliation
Time Period
Scientist C
Central Drug Research Institute, Lucknow, India
2010-Present
Post Doctoral Fellow
School of Pharmacy, University of North Carolina at Chapel Hill, USA
2007-2009
Area of Specialization:
BIO-ORGANIC & MEDICINAL CHEMISTRY
Research Summary:
Development of sigma receptor targeted drugs for breast cancer
Development of PSMA targeted multi functional nanoparticles
Development of estrogen receptor targeting siRNA drugs to treat breast cancer
Publications:
1.
Sinha, S., Roy, S., Reddy, Bathula. S. R., Pal, K., Sudhakar, G., Iyer, S., Dutta, S., Wang, E., Vohra, P. K., Roy, K. R., Reddanna, P., Mukhopadhyay, D. and Banerjee, R. A lipid-modified estrogen derivative that treats breast cancer independent of estrogen receptor expression through simultaneous induction of autophagy and apoptosis. Molecular Cancer Research : MCR. 2011. 9, 364-374. [PubMed]
2.
Chen, Y., Bathula, S. R. , Yang, Q. and Huang, L. Targeted nanoparticles deliver siRNA to melanoma. The Journal of Investigative Dermatology. 2010. 130, 2790-2798. [PubMed]
3.
Liu, F., Park, J. Y., Zhang, Y., Conwell, C., Liu, Y., Bathula, S. R. and Huang, L. Targeted cancer therapy with novel high drug-loading nanocrystals. Journal of Pharmaceutical Sciences. 2010. 99, 3542-3551. [PubMed]
4.
Chen, Y., Bathula, S. R. , Li, J. and Huang, L. Multifunctional nanoparticles delivering small interfering RNA and doxorubicin overcome drug resistance in cancer. The Journal of Biological Chemistry. 2010. 285, 22639-22650. [PubMed]
5.
Chen, Y., Sen, J., Bathula, S. R. , Yang, Q., Fittipaldi, R. and Huang, L. Novel cationic lipid that delivers siRNA and enhances therapeutic effect in lung cancer cells. Molecular Pharmaceutics. 2009. 6, 696-705. [PubMed]
6.
Majeti, B. K., Singh, R. S., Yadav, S. K., Bathula, S. R. , Ramakrishna, S., Diwan, P. V., Madhavendra, S. S. and Chaudhuri, A. Enhanced intravenous transgene expression in mouse lung using cyclic-head cationic lipids. Chemistry & Biology. 2004. 11, 427-437. [PubMed]
Book Chapters:
Reddy BS and Leaf Huang Gene Therapy with plasmid DNA, Medicinal Chemistry and Drug Discovery(In press).
Education
::
Ph.D. in Chemistry,
Osmania University, Hyderabad, India
::
M.Sc. in Chemistry,
Osmania University, Hyderabad, India
Honors and Awards
::
Awarded Director special appreciation award for publishing best papers in 2005 from IICT, Hyderabad.
::
Awarded KVR young scientist award for Year 2006 - 07 by Dr.K.V.Rao Scientific Society, 8-2-293/82/A/431/A, Road No. 22, Jubilee Hills, Hyderabad – 500 033, Website: www.kvrss.com
Type of Neoplasms
Breast
Female