INCREDB ID : 224
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Neelam V. Shirsat, Ph.D.
Scientific Officer F 
 
Advanced Centre for Treatment Research and Education in Cancer
Shirsat Lab
Tata Memorial Centre, Kharghar
Navi Mumbai - 410 208   
Maharashtra   
 
E-mail: nshirsat@actrec.gov.in
Phone: +91-22-27405016
Fax: +91-22-27412894
 
URL: http://www.actrec.gov.in/pi-webpages/NeelamShirsat/neelam-index.htm
 
Positions Held:
Position Affiliation Time Period
Scientific Officer F Advanced Centre for Treatment, Research and Education in Cancer, Navi Mumbai, India Present
Principal Investigator Advanced Centre for Treatment, Research and Education in Cancer, Navi Mumbai, India
 
Area of Specialization:
Neuro-Oncology
Research Summary:
Role of Fra-1, a component of AP-1 transcription factor in glioma cell proliferation, differentiation and apoptosis
Molecular mechanism of tamoxifen-induced apoptosis of glioma cells
Studies on the pathogenesis of medulloblastoma, a common childhood brain tumour
 
Publications:
1. Ranade, K. J., Nerurkar, A. V., Phulpagar, M. D. and Shirsat, N. V.  Expression of survivin and p53 proteins and their correlation with hormone receptor status in Indian breast cancer patients. Indian Journal of Medical Sciences. 2009.  63, 481-490. [PubMed]
2. Jane, C., Nerurkar, A. V., Shirsat, N. V., Deshpande, R. B., Amrapurkar, A. D. and Karjodkar, F. R.  Increased survivin expression in high-grade oral squamous cell carcinoma: a study in Indian tobacco chewers. Journal of Oral Pathology & Medicine. 2006.  35, 595-601. [PubMed]
3. Harmalkar, M. N. and Shirsat, N. V.  Staurosporine-induced growth inhibition of glioma cells is accompanied by altered expression of cyclins, CDKs and CDK inhibitors. Neurochemical Research. 2006.  31, 685-692. [PubMed]
4. Moodbidri, M. S. and Shirsat, N. V.  Induction of BAALC and down regulation of RAMP3 in astrocytes treated with differentiation inducers. Cell Biology International. 2006.  30, 210-213. [PubMed]
5. Patole, J., Padhye, S., Moodbidri, M. S. and Shirsat, N.  Antiproliferative activities of iron and platinum conjugates of salicylaldehyde semi-/thiosemicarbazones against C6 glioma cells. European Journal of Medicinal Chemistry. 2005.  40, 1052-1055. [PubMed]
6. Moodbidri, M. S. and Shirsat, N. V.  Activated JNK brings about accelerated apoptosis of Bcl-2-overexpressing C6 glioma cells on treatment with tamoxifen. Journal of Neurochemistry. 2005.  92, 1-9. [PubMed]
7. Shirsat, N. V. and Shaikh, S. A.  Overexpression of the immediate early gene fra-1 inhibits proliferation, induces apoptosis, and reduces tumourigenicity of c6 glioma cells. Experimental Cell Research. 2003.  291, 91-100. [PubMed]
8. Shirsat, N. V., Kayal, J. J., Shaikh, S. and Mehta, A.  Growth inhibition and differentiation of C6 glioma cells on treatment with hmba. Cell Biology International. 2001.  25, 621-627. [PubMed]
9. Shirsat N. V.  HMBA inhibits growth and induces differentiation of astrocytes from neonatal rat brain. Neuroreport. 1999.  10, 3755-3758. [PubMed]

 
Grant Support:
Project Title Role Funding Agency Sanction Number Sanction Date
Role of LLGL1, a gene controlling asymmetric cell division of stem cells in pathogenesis of medulloblastoma a pediatric malignant brain tumor
Studies on the molecular mechanism of Tamoxifen - induced apoptosis pf astrocutoma cells Principal Investigator Indian Council of Medical Research, Goverment of India 2003-2006

 
 
 
Education 
::
Ph.D.
Type of Neoplasms
 
Head and Neck
Central nervous system
  Last modified on : Mar 4, 2011
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