Thangarajan Rajkumar, M.D., D.M., Ph.D.
Cancer Institute
Department of Molecular Oncology
Adyar
Chennai - 600 020
Tamil Nadu
E-mail: drtrajkumar@gmail.com, cancer_institute_wia@vsnl.com
Phone: +91-44-22350131, 22350241
Fax: +91-44-24912085
URL: https://www.noktaseksshop.com
Positions Held:
Position Affiliation Time Period
Professor and Head
Cancer Institute, Chennai, India
2008-Present
Director
Cancer Institute, Chennai, India
2006-2008
Scientific Director, Professor and Head
Cancer Institute, Chennai, India
2000-2006
Director
Cancer Institute, Chennai, India
2000-2000
Deputy Director
Cancer Institute, Chennai, India
1997-2000
Chairman
Cancer Institute, Chennai, India
1996-1997
Professor and Head
Cancer Institute, Chennai, India
1994-1996
Clinical Research Fellow
Hammersmith Hospital, London, UK
1991-1994
Reader
Cancer Institute, Chennai, India
1990-1994
Assistant Professor
Cancer Institute, Chennai, India
1988-1990
Area of Specialization:
Medical Oncology
Publications:
1.
Peixoto, A., Santos, C., Pinheiro, M., Pinto, P., Soares, M. J., Rocha, P., Gusmao, L., Amorim, A., van, d. e. r., Gerdes, A. M., Thomassen, M., Kruse, T. A., Cruger, D., Sunde, L., Bignon, Y. J., Uhrhammer, N., Cornil, L., Rouleau, E., Lidereau, R., Yannoukakos, D., Pertesi, M., Narod, S., Royer, R., Costa, M. M., Lazaro, C., Feliubadalo, L., Grana, B., Blanco, I., de, l. a., Caldes, T., Maillet, P., Benais-Pont, G., Pardo, B., Laitman, Y., Friedman, E., Velasco, E. A., Duran, M., Miramar, M. D., Valle, A. R., Calvo, M. T., Vega, A., Blanco, A., Diez, O., Gutierrez-Enriquez, S., Balmana, J., Ramon, Y., Alonso, C., Baiget, M., Foulkes, W., Tischkowitz, M., Kyle, R., Sabbaghian, N., Ashton-Prolla, P., Ewald, I. P., Rajkumar, T. , Mota-Vieira, L., Giannini, G., Gulino, A., Achatz, M. I., Carraro, D. M., de, P., Remenieras, A., Benson, C., Casadei, S., King, M. C., Teugels, E. and Teixeira, M. R. International distribution and age estimation of the Portuguese BRCA2 c.156_157insAlu founder mutation. Breast Cancer Research and Treatment. 2010. [PubMed]
2.
Rajkumar, T. , Sabitha, K., Vijayalakshmi, N., Shirley, S., Bose, M. V., Gopal, G. and Selvaluxmy, G. Identification and validation of genes involved in cervical tumourigenesis. BMC Cancer. 2011. 11, 80. [PubMed]
3.
Rajkumar, T. Personalized medicine: FAQs. Indian Journal of Medical and Paediatric Oncology. 2010. 31, 72-74. [PubMed]
4.
Rajkumar, T. , Vijayalakshmi, N., Gopal, G., Sabitha, K., Shirley, S., Raja, U. M. and Ramakrishnan, S. A. Identification and validation of genes involved in gastric tumorigenesis. Cancer Cell International. 2010. 10, 45. [PubMed]
5.
Rajkumar, T. , Vijayalakshmi, N., Sabitha, K., Shirley, S., Selvaluxmy, G., Bose, M. V. and Nambaru, L. A 7 gene expression score predicts for radiation response in cancer cervix. BMC Cancer. 2009. 9, 365. [PubMed]
6.
Sudhakar, N., Nancy, N. K., Rajalekshmy, K. R. and Rajkumar, T. Diversity of T-cell receptor gene rearrangements in South Indian patients with common acute lymphoblastic leukemia. Iranian Journal of Immunology . 2009. 6, 141-146. [PubMed]
7.
Soumittra, N., Meenakumari, B., Parija, T., Sridevi, V., Nancy, K. N., Swaminathan, R., Rajalekshmy, K. R., Majhi, U. and Rajkumar, T. Molecular genetics analysis of hereditary breast and ovarian cancer patients in India. Hereditary Cancer in Clinical Practice. 2009. 7, 13. [PubMed]
8.
Nambaru, L., Meenakumari, B., Swaminathan, R. and Rajkumar, T. Prognostic significance of HPV physical status and integration sites in cervical cancer. Asian Pacific Journal of Cancer Prevention. 2009. 10, 355-360. [PubMed]
9.
Murhekar, K. M., Anuratha, J. N., Majhi, U. and Rajkumar, T. Expression of human chorionic gonadotropin beta in gastric carcinoma: A retrospective immunohistochemical study. Indian Journal of Medical and Paediatric Oncology. 2009. 30, 99-102. [PubMed]
10.
Samson, M., Rama, R., Swaminathan, R., Sridevi, V., Nancy, K. N. and Rajkumar, T. CYP17 (T34C), CYP19 (Trp39Arg), and FGFR2 (C906T) polymorphisms and the risk of breast cancer in south Indian women. Asian Pacific Journal of Cancer Prevention. 2009. 10, 111-114. [PubMed]
11.
Suneetha, K. J., Nancy, K. N., Rajalekshmy, K. R., Sagar, T. G. and Rajkumar, T. Role of GSTM1 (Present/Null) and GSTP1 (Ile105Val) polymorphisms in susceptibility to acute lymphoblastic leukemia among the South Indian population. Asian Pacific Journal of Cancer Prevention : APJCP. 2008. 9, 733-736. [PubMed]
12.
Sasikala, P. S., Nirmala, K., Sundersingh, S., Mahji, U. and Rajkumar, T. Frequency and distribution of Epstein-Barr virus infection and its association with P53 expression in a series of primary nodal non-Hodgkin lymphoma patients from South India. International Journal of Laboratory Hematology. 2010. 32, 56-64. [PubMed]
13.
Boyle, P., Anderson, B. O., Andersson, L. C., Ariyaratne, Y., Auleley, G. R., Barbacid, M., Bartelink, H., Baselga, J., Behbehani, K., Belardelli, F., Berns, A., Bishop, J., Brawley, O., Burns, H., Clanton, M., Cox, B., Currow, D., Dangou, J. M., de, V., Dinshaw, K., Eggermont, A., Fitzpatrick, J., Forstmane, M., Garaci, E., Gavin, A. T., Kakizoe, T., Kasler, M., Keita, N., Kerr, D., Khayat, D., Khleif, S., Khuhaprema, T., Knezevic, T., Kubinova, R., Mallath, M., Martin-Moreno, J., McCance, D., McVie, J. G., Merriman, A., Ngoma, T., Nowacki, M., Orgelbrand, J., Park, J. G., Pierotti, M., Ashton, L. P., Puska, P., Escobar, C. V., Rajan, B., Rajkumar, T. , Ringborg, U., Robertson, C., Rodger, A., Roovali, L., Santini, L. A., Sarhan, M., Seffrin, J., Semiglazov, V., Shrestha, B. M., Soo, K. C., Stamenic, V., Tamblyn, C., Thomas, R., Tuncer, M., Tursz, T., Vaitkiene, R., Vallejos, C., Veronesi, U., Wojtyla, A., Yach, D., Yoo, K. Y., Zatonski, W., Zaridze, D., Zeng, Y. X., Zhao, P. and Zheng, T. Need for global action for cancer control. Annals of Oncology . 2008. 19, 1519-1521. [PubMed]
14.
Rajkumar, T. and Yamuna, M. Multiple pathways are involved in drug resistance to doxorubicin in an osteosarcoma cell line. Anti-cancer Drugs. 2008. 19, 257-265. [PubMed]
15.
Sudhakar, N., Nirmala, K., Rajalekshmy, K. R. and Rajkumar, T. Does TAL-1 deletion contribute to the high incidence of T-cell acute lymphoblastic leukemia in South Indian patients? Asian Pacific Journal of Cancer Prevention. 2008. 9, 127-130. [PubMed]
16.
Vijayalakshmi, N., Selvaluxmi, G., Majhi, U. and Rajkumar, T. Alterations found in pl6/Rb/cyclin D1 pathway in the dysplastic and malignant cervical epithelium. Oncology Research. 2007. 16, 527-533. [PubMed]
17.
Rajkumar, T. , Samson, M., Rama, R., Sridevi, V., Mahji, U., Swaminathan, R. and Nancy, N. K. TGFbeta1 (Leu10Pro), p53 (Arg72Pro) can predict for increased risk for breast cancer in south Indian women and TGFbeta1 Pro (Leu10Pro) allele predicts response to neo-adjuvant chemo-radiotherapy. Breast Cancer Research and Treatment. 2008. 112, 81-87. [PubMed]
18.
Samson, M., Swaminathan, R., Rama, R., Sridevi, V., Nancy, K. N. and Rajkumar, T. Role of GSTM1 (Null/Present), GSTP1 (Ile105Val) and P53 (Arg72Pro) genetic polymorphisms and the risk of breast cancer: a case control study from South India. Asian Pacific Journal of Cancer Prevention. 2007. 8, 253-257. [PubMed]
19.
Sudhakar, N., Nancy, N. K., Rajalekshmy, K. R., Ramanan, G. and Rajkumar, T. T-cell receptor gamma and delta gene rearrangements and junctional region characteristics in south Indian patients with T-cell acute lymphoblastic leukemia. American Journal of Hematology. 2007. 82, 215-221. [PubMed]
20.
Parija, T., Shirley, S., Uma, S., Rajalekshmy, K. R., Ayyappan, S. and Rajkumar, T. Type 1 (11;22)(q24:q12) translocation is common in Ewing's sarcoma/peripheral neuroectodermal tumour in south Indian patients. Journal of Biosciences. 2005. 30, 371-376. [PubMed]
21.
Rajkumar, T ., Soumittra, N., Vidubala, E., Sridevi, V., Mahajan, V., Ramanan, S. and Vijaya, S. Organization and running of the first comprehensive hereditary cancer clinic in India. Hereditary Cancer in Clinical Practice. 2005. 3, 165-170. [PubMed]
22.
Rajkumar, T. , Soumittra, N., Pandey, D., Nancy, K. N., Mahajan, V. and Majhi, U. Mutation analysis of hMSH2 and hMLH1 in colorectal cancer patients in India. Genetic Testing. 2004. 8, 157-162. [PubMed]
23.
Raj, E. H., Skinner, A., Mahji, U., Nirmala, K. N., Ravichandran, K., Shanta, V., Hurst, H. C., Gullick, W. J. and Rajkumar, T. Neuregulin 1-alpha expression in locally advanced breast cancer. Breast. 2001. 10, 41-45. [PubMed]
24.
Herrero, R., Castellsague, X., Pawlita, M., Lissowska, J., Kee, F., Balaram, P., Rajkumar, T. , Sridhar, H., Rose, B., Pintos, J., Fernandez, L., Idris, A., Sanchez, M. J., Nieto, A., Talamini, R., Tavani, A., Bosch, F. X., Reidel, U., Snijders, P. J., Meijer, C. J., Viscidi, R., Munoz, N. and Franceschi, S. Human papillomavirus and oral cancer: the International Agency for Research on Cancer multicenter study. Journal of the National Cancer Institute. 2003. 95, 1772-1783. [PubMed]
25.
Rajkumar, T. , Soumittra, N., Nancy, N. K., Swaminathan, R., Sridevi, V. and Shanta, V. BRCA1, BRCA2 and CHEK2 (1100 del C) germline mutations in hereditary breast and ovarian cancer families in South India. Asian Pacific Journal of Cancer Prevention. 2003. 4, 203-208. [PubMed]
26.
Franceschi, S., Rajkumar, T. , Vaccarella, S., Gajalakshmi, V., Sharmila, A., Snijders, P. J., Munoz, N., Meijer, C. J. and Herrero, R. Human papillomavirus and risk factors for cervical cancer in Chennai, India: a case-control study. International Journal of Cancer. 2003. 107, 127-133. [PubMed]
27.
Rajkumar, T. , Franceschi, S., Vaccarella, S., Gajalakshmi, V., Sharmila, A., Snijders, P. J., Munoz, N., Meijer, C. J. and Herrero, R. Role of paan chewing and dietary habits in cervical carcinoma in Chennai, India. British Journal of Cancer. 2003. 88, 1388-1393. [PubMed]
28.
Rajkumar, T. , Sridhar, H., Balaram, P., Vaccarella, S., Gajalakshmi, V., Nandakumar, A., Ramdas, K., Jayshree, R., Munoz, N., Herrero, R., Franceschi, S. and Weiderpass, E. Oral cancer in Southern India: the influence of body size, diet, infections and sexual practices. European Journal of Cancer Prevention . 2003. 12, 135-143. [PubMed]
29.
Vijayalakshmi, N., Selvaluxmi, G., Mahji, U. and Rajkumar, T. C-myc oncoprotein expression and prognosis in patients with carcinoma of the cervix: an immunohistochemical study. European Journal of Gynaecological Oncology. 2002. 23, 135-138. [PubMed]
30.
Balaram, P., Sridhar, H., Rajkumar, T. , Vaccarella, S., Herrero, R., Nandakumar, A., Ravichandran, K., Ramdas, K., Sankaranarayanan, R., Gajalakshmi, V., Munoz, N. and Franceschi, S. Oral cancer in southern India: the influence of smoking, drinking, paan-chewing and oral hygiene. International Journal of Cancer. 2002. 98, 440-445. [PubMed]
31.
Nirmala, K., Rajalekshmy, K. R., Raman, S. G., Shanta, V. and Rajkumar, T. PCR-heteroduplex analysis of TCR gamma, delta and TAL-1 deletions in T-acute lymphoblastic leukemias: implications in the detection of minimal residual disease. Leukemia Research. 2002. 26, 335-343. [PubMed]
32.
Rajkumar, T. , Rajan, S., Baruah, R. K., Majhi, U., Selvaluxmi, G. and Vasanthan, A. Prognostic significance of Bcl-2 and p53 protein expression in stage IIB and IIIB squamous cell carcinoma of the cervix. European Journal of Gynaecological Oncology. 1998. 19, 556-560. [PubMed]
33.
Jayashree, B., Visalakshi, V., Rajalakshmi, K. R., Sukumaran, M. S., Moni, M. S., Rajkumar, T. and Deshmukh, S. Characterization of mouse fibroblast (NIH3T3) and fibrosarcoma cell lines (WEHI-164 and MFS 8) using PMRS. Indian Journal of Biochemistry & Biophysics. 1998. 35, 108-114. [PubMed]
34.
Rajkumar, T. , Stamp, G. W., Pandha, H. S., Waxman, J. and Gullick, W. J. Expression of the type 1 tyrosine kinase growth factor receptors EGF receptor, c-erbB2 and c-erbB3 in bladder cancer. The Journal of Pathology. 1996. 179, 381-385. [PubMed]
35.
Hunt, C. R., Hale, R. J., Armstrong, C., Rajkumar, T. , Gullick, W. J. and Buckley, C. H. c-erbB-3 proto-oncogene expression in uterine cervical carcinoma. International Journal of Gynecological Cancer. 1995. 5, 282-285. [PubMed]
36.
Rajkumar, T. and Gullick, W. J. A monoclonal antibody to the human c-erbB3 protein stimulates the anchorage-independent growth of breast cancer cell lines. British Journal of Cancer. 1994. 70, 459-465. [PubMed]
37.
Shiekh, A. A., Sagar, T. C., Maitreyan, V., Rajkumar, T. , Majhi, U. and Shanta, V. Secretory immunoblastic lymphoma. The Journal of the Association of Physicians of India. 1994. 42, 155-156. [PubMed]
38.
Rajkumar, T. and Gullick, W. J. The type I growth factor receptors in human breast cancer. Breast Cancer Research and Treatment. 1994. 29, 3-9. [PubMed]
39.
Sanidas, E. E., Filipe, M. I., Linehan, J., Lemoine, N. R., Gullick, W. J., Rajkumar, T. and Levison, D. A. Expression of the c-erbB-3 gene product in gastric cancer. International Journal of Cancer. 1993. 54, 935-940. [PubMed]
40.
Rajkumar, T. , Gooden, C. S., Lemoine, N. R., Gullick, W. J. and Goden, C. S. Expression of the c-erbB-3 protein in gastrointestinal tract tumours determined by monoclonal antibody RTJ1. The Journal of Pathology. 1993. 170, 271-278. [PubMed]
41.
Rajkumar, K., Rajkumar, T. , Sagar, T. G., Maitreyan, V. and Shanta, V. Cryptococcal meningitis in a patient with Hodgkin's lymphoma. The Journal of the Association of Physicians of India. 1992. 40, 707-708. [PubMed]
42.
Rajkumar, T. , Maitreyan, V., Sagar, T. G., Raj, E., Chandrasekhar, A., Mayilvahanan, N., Vasanthan, A., Sukumaran, M. S. and Shanta, V. Induction chemotherapy in non-metastatic high grade osteo sarcomas--results of pilot study at Cancer Institute (WIA), Madras. Indian Journal of Cancer. 1992. 29, 139-142. [PubMed]
43.
Rajkumar, T. , Sagar, T. G., Maitreyan, V., Vasanthan, A., Devika, A., Sastry, D. V. and Shanta, V. Germ-cell tumours of the ovary--treatment and results at Cancer Institute, Madras. Indian Journal of Cancer. 1992. 29, 18-23. [PubMed]
44.
Rajkumar, K., Rajkumar, T. , Sagar, T. G., Maitreyan, V. and Shanta, V. Cryptococcal meningitis in a patient with Hodgkin's lymphoma. The Journal of the Association of Physicians of India. 1991. 39, 785. [PubMed]
45.
Kumar, L., Rajkumar, T. , Raghunath, R. a. o., Usha, D., Sagar, T. G. and Shanta, V. Intrathecal methotrexate toxicity. The Journal of the Association of Physicians of India. 1989. 37, 351. [PubMed]
46.
Rajkumar, T. , Stamp, G. W., Hughes, C. M. and Gullick, W. J. c-erbB3 protein expression in ovarian cancer. Clinical Molecular Pathology. 1996. 49, M199-202. [PubMed]
47
Krishnamurthy, S., Shantha V, Rajkumar, T . Drug therapy in oncology - its priority and economics- the Institute experience. Indian Journal of Cancer Chemotherapy . 1988. 10: 73-82.
48.
Rajkumar, T ., Hemanthraj, E., Venkataraman, M.S., Sukumaran, M.S. and Shantha, V. Primary splenic lymphoma with pancreatic involvement - A case report. Indian Journal of Cancer Chemotherapy . 1989 . 11: 53-55.
49.
Sagar, T.,G., Maitreyan, V., Rajkumar, T. , Maji, U. and Shantha, V. Primary malignant lymphoma of the minor salivary gland - A case report. Indian Journal of Cancer Chemotherapy. 1990. 12: 71-73.
50.
Rajkumar, T. , Maitreyan, V., Sagar, T.G., Vasanthan, A., Shastr,i D.V.L.N and Shantha, V. Germ cell tumour of the ovary - management and results at the Institute. Indian Journal of Cancer . 1992. 29: 18-23.
51.
Rajkumar, T. , Maitreyan, V., Sagar, T.G., Vasanthan, A., Hemanthraj, E., Aruna, C., and Shantha, V. Neo-adjuvant chemotherapy in osteosarcoma - a pilot trial. Indian Journal of Cancer , 1992. 29: 139-142.
52.
Rajkumar, T. , Maji, U., Mallikarjuna, V.S., Shantha, V. and Gullick, W.J. c-erbB3 expression in cervical tumours as determined by the monoclonal antibody RTJ2. International Journal of Oncology. 1995. 6: 105-109.
53.
Rajkumar, T. , Hollywood, D.,P., Hurst, H., and Gullick, W.,J. c-erbB3 expression in breast tumour derived cell lines. The Breast. 1995. 4, 84-91.
54.
Rajkumar, T., and Gullick, W.,J. The type 1 (EGF receptor) growth factor receptor family and their ligands: their role in human cancers. Molecular Biology of cancer. 1996. 3-14.
55.
Rajkumar, T. , Stamp, G., Panda, H., Waxman, J., and Gullick, W.,J. Type 1 growth factor receptors in bladder cancer - An immunohistochemical study. Journal of Pathology . 1996.179, 381-385.
56.
Rajkumar, T. , Stamp, G., Hughes, C.,M., and Gullick, W.,J. Immunohistochemical analysis of c-erbB3 protein expression in ovarian carcinomas. Journal of Clinical Pathology . 1996. 49: M199-M202.
57.
Pushpa, V., Raghunathan, K., Majhi, U., Pandit, R.V., Shanthi, G., Rajkumar, T . Emperipolesis - An electron microscopic characteristic in RDD (Rosai-Dorfman Disease) - A case report. Indian Journal of Medical & Paediatric Oncology. 1997. 18, 14-16.
58.
Susheela, M., Parameswari, E., Rajalakshmi, K.,R., Devarajan, S., Shanta, V., Rajkumar, T. Cytogenetic studies in ALL - Prognostic implications. Indian Journal of Hematology & Blood Transfusion . 1997. 15,11-15.
59.
Jayashree, B., Deshmukh, S., Visalakshi, V., Rajalakshmi, K.,R., Sukumaran, M.,S., Moni, M.,S., Rajkumar, T . Proton Magnetic Resonance spectroscopy of murine fibrosarcoma ,cell lines. Indian Journal of Biochemistry and Biophysics. 1998. 35, 108-114.
60.
Rajkumar, T. , Sharmila, R., Majhi, U., Selvaluxmi, G., Vasanthan, A., Shanta, V. Bcl-2 and p53 expression in stage IIB and IIIB cervical cancers. European Journal of Gynaecological Oncology . 1998. 19, 556-560.
61.
Jayashree, B., Deshmukh, S., Rajkumar, T . Assessment of human sarcoma tissues by proton NMR spectroscopy: correlation with histopathology. Current Science. 1999. 77, 587-592.
62.
Jayashree, B., Rajalakshmi, K.,R.,R., Deshmukh, S., Rajkumar, T . Two dimensional NMR spectroscopic study of fibroblast and fibrosarcoma cell lines. Current Science. 1999. 77, 706–709.
63.
Rajkumar, T. Growth factor and growth factor receptors. Current Science. 2001. 81, 535-541.
64.
Rajkumar, T., and Vijayalakshmi, N. Is there a role for surrogate markers of pre-malignant lesions of cervix in India? Indian National Science Academy. 2003.. B69. 73-82.
65.
Herrero, R., Castellsague, X., Pawlita, M., Lissowska, J., Kee, F., Balaram, P., Rajkumar, T. , Sridha,r H., Rose, B., Pintos, J., Fernandez, L., Idris, A., Martinez, C., Nieto, A., Talamini, R., Tavani, A., Bosch, F.,X., Snijders, P.,J.,F., Viscidi, R., Munoz, N., Franceschi, S. The viral etiology of oral cancer: evidence from the IARC multicentric study. JNCI. 2003. 95, 1772-1783.
66.
Gopal, G., and Rajkumar T. Variant of mitochondrial ribosomal protein s28 (mrps28) gene is differentially expressed in response to radiation in a cervical carcinoma derived cell line. Indian Journal of Biochem Biophysics. 2005. 42, 81-86.
67.
Rajkumar, T. , Gopal, G., Selvaluxmi, G., and Rajalekshmy, K.,R. CDC27 is involved in radiation response in squamous cell carcinoma of the cervix. Indian Journal of Biochemistry and Biophysics. 2005. 45, 271-278.
68.
Rajkumar, T., Soumittra, N., Vidubala, E., Sridevi, V., Mahajan, V., Ramanan, S.,G., Vijaya, S. Organization and running of the first comprehensive hereditary cancer clinic in India. Hereditary Cancer in Clinical Practice . 2005. 3, 165-170.
69.
Ramanathan, U.,S. and Rajkumar, T . DNA Microarray and breast cancer – A review. International Journal of Human Genetics. 2007. 7, 49-56.
70.
Rajkumar, T. Hereditary Ovarian cancers. Indian Journal of Medical Paediatric Oncology . 2009. 30, 48.
71.
Vijayalakshmi, N., Jully, B., Sabitha, K., and Rajkumar, T . Computational prediction of Intrinsic disorder of EWS-FLI fusion protein. Bioinformatics Trend . 2009, 4:53-61.
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Book Chapters:
Rajkumar, T., and Priya . Phase-1 clinical trial of dendritic cell vaccines for human papillomavirus positive cervical cancer. In: Treatment of advanced stage cancers, Talwar, G.,P., and O.P.Sood, O., P., Eds.Narosa Publishing House, New Delhi, 2009, pp 140-141.
Sridevi, V., and Rajkumar, T . Genetics and Genomics of ovarian cancer. In: Ovarian Cancer - comprehensive and contemporary management. Chitrathara, K., Rajaram, S., Amita Maheshwari, A. Eds. Jaypee Brothers,New Delhi. 2008.
Rajkumar, T. and Gullick, W.,J. The production of antibodies to growth factor receptors using synthetic peptides as immunogens. In: Clinical Gene Analysis and Manipulation: tools, techniques and trouble-shooting. Jankowski, J., A., Z and Polak, J., M. Eds. Cambridge University Press, Cambridge, 1996. pp 99-110.
Shantha, V. and Rajkumar, T . Malignant epithelial tumours of the ovary - concepts in the diagnosis and
Nancy, N., and Rajkumar, T . Detection of minimal residual disease in ALL. Lalit Kumar Editor. Progress in Haematologic Oncology. The Advanced Research Foundation, New York. 2003. pp 45-60.
Grant Support:
Project Title Role Funding Agency Sanction Number Sanction Date
Development of structure based drugs against EWS:FLI fusion protein seen in Ewing’s sarcoma
Department of Science & Technology, Government of India
Gene expression studies in cervical, breast and gastric cancers
Department of Science & Technology, Government of India
Minimal Residual Disease detection in cervical cancer – Indo-German collaborative project
Genetic polymorphisms and breast cancer
Chennai Willingdon Corporate Foundation, India
Development and clinical evaluation of dendritic cell vaccine for HPV related cervix cancer
Department of Biotechnology, Government of India
Development and clinical evaluation of dendritic cell vaccine for HPV related cervix cancer
Department of Biotechnology, Government of India
Mutation analysis for hereditary breast cancers and hereditary colo-rectal cancers and their prognostic significance
Department of Biotechnology, Government of India
Establishing a Population based Hereditary Cancer Registry covering Madras Metropolitan Area
Cancer Institute (WIA), Chennai, India
Identification of genes involved in drug resistance in osteosarcomas using differential display and microarray
Identification of genes involved in radio-responsiveness in cervical cancer using differential display
Department of Atomic Energy
HPV in Oral Cancer
International Agency for Research on Cancer, Lyon, France
HPV in cervical cancer - a case control study
International Agency For Research On Cancer, Lyon, France
Cell cycle regulatory molecules in cervical cancer
Department of Science & Technology, Government of India
Biologic characterisation of T-ALL
National Cancer Institute, National Institute of Health, Maryland, USA
BCL-2 and p53 expression in cervical cancers
Study of type 1 tyrosine kinase growth factor receptors and their growth factors in breast and cervical cancers
PCR based detection of Minimal residual disease in Acute lymphoblastic leukemias
National Cancer Institute, National Institute of Health, Maryland, USA
My CV: Download
Education
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M.B.B.S. in Medicine,
Madras Medical College, University of Madras, India, 1975-1982
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M.D. in General Medicine,
Madras Medical College, University of Madras, India, 1982-1985
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D.M. in Medical Oncology,
Cancer Institute (WIA), University of Madras, India, 1986-1988
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Ph.D. in Molecular Oncology, ,
Science Royal Postgraduate Medical School, Hammersmith Hospital, London, UK, 1991-1994
Honors and Awards
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2011, Sir Dorabji Tata Oration, Indian Cancer Congress
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2010, Kobayashi Foundation Award for Cancer Research
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2008, Shri Ramniklal J Kinarivala Cancer Research Award
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2007, Elected as a Fellow of the National Academy of Medical Sciences, India
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2006, Late Shri Muthuswamy Naidu Memorial Oration
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Inventors Award from Imperial Cancer Research Fund, UK
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1991, Commonwealth Scholarship Royal Postgraduate Medical School, Hammersmith Hospital, London
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Dr. Edmund Leorde Chalke Prize, Best Post-graduate in Medicine
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Johnstone Gold Medal - Best outgoing M.B.B.S student
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Col.K.G. Pandalai Charitable - Best outgoing M.B.B.S. student
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Dr. Senthilnathan Gold Medal - Best outgoing male M.B.B.S. student
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Dr.J. A. S. Masilamani Memorial Gold Medal, Highest number of marks in university
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Dr.G. Rama Rao Gold Medal - Anatomy
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Dr. Rajasekara Reddy Prize - Anatomy
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Dr. K. Govindareddy Memorial - Highest number of marks in University
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Dr. Sundarareddy Memorial - Highest number of marks in University
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Col.Van Geyzel Prize - Biochemistry
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Dr.Samuel Jesudoss Prize-Pharmacology
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Bradfield Prize, Highest number of University examination marks in Anatomy and Surgery
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Certificate of Merit- Physiology
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Certificate of Merit- Pharmacology
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Nutrition Prize-Essay and Elocution
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Certificate of Honour- Bacteriology
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Certificate of Honour-Pharmacology
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DBT Nominee for Institutional Bio-Safety Committee of CMC, Vellore
Member
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Programme Advisory Committee, Dept. of Science and Technology
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Task Force on Multi centre National programme on cervical cancer, Dept. of Biotechnology, Govt. of India
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Member, Thematic Review Committee for Health Informatics, CDAC, Dept. of Information and Technology, Govt. of India
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Member Secretary, Scientific Advisory committee of Cancer Institute (WIA)
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Member, Scientific Advisory committee of Vision Research Foundation, Sankara Nethralaya, Chennai
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Reviewer of projects from Department of Science and Technology, Department of Biotechnology, Indian Council of Medical Research, Government of India.
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Projects reviewer for Welcome Trust, UK and European Commission
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Reviewer of British Journal of Cancer, Asia Pacific Journal of Cancer Prevention, Indian Journal of Biochemistry and Biophysics, Indian Journal of Medical and Paediatric Oncology
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Member of Fellow of the National Academy of Medical Sciences, Indian Society of Oncology, Indian Association of Cancer Research, Indian Society of Human Genetics, Indian Society of Medical and Paediatric Oncology, Asia Pacific Organisation for Cancer Prevention
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Member, Editorial Board, Indian Journal of Cancer, Hereditary Cancer in Clinical Practice
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Member, Ethical committee of YRG AIDS Research Foundation
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Member, Subject Expert Committee on Life Sciences of the FIST Program, Dept. of Science and Technology, Govt. of India
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• Member, Thematic Review Committee for Health Informatics, CDAC, Dept. of Information and Technology, Govt. of India
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• Member, Screening Committee for projects on RNAi technology for its application in agriculture and medicine, Dept. of Biotechnology, Govt. of India
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• Member, Technical Resource Group on Cancer, Ministry of Health and Family Welfare, Govt. of India
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• Member, International Collaboration of Epidemiological Studies of Cervical Cancer