INCREDB ID : 19
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Bhaskar Saha, Ph.D.
Scientist E 
 
National Centre for Cell Science
NCCS Complex, Pune University Campus, Ganeshkhind
Pune - 411 007   
Maharashtra   
 
E-mail: sahab@nccs.res.in
Phone: +91-20-25708139, 25708000, Extn. 8139
 
URL: http://www.nccs.res.in/saha1.html
 
Positions Held:
Position Affiliation Time Period
Scientist E National Centre for Cell Science, Pune, India Present
 
Area of Specialization:
Immunology
Research Summary:
Leishmania-macrophage interaction
Characterization of neonatal immune response
Dendritic cell subset mediated priming against prostate cancer
Development and regulation of regulatory T cells in leishmaniasis
Dendritic cell subsets in leishmaniasis and regulation of T cell response
 
Publications:
1. Paila, Y. D., Saha, B. and Chattopadhyay, A.  Amphotericin B inhibits entry of Leishmania donovani into primary macrophages. Biochemical and Biophysical Research Communications. 2010.  399, 429-433. [PubMed]
2. Martin, S., Agarwal, R., Murugaiyan, G. and Saha, B.  CD40 expression levels modulate regulatory T cells in Leishmania donovani infection. Journal of Immunology. 2010.  185, 551-559. [PubMed]
3. Bhattacharya, P., Bhattacharjee, S., Gupta, G., Majumder, S., Adhikari, A., Mukherjee, A., Majumdar, S. B., Saha, B. and Majumdar, S.  Arabinosylated lipoarabinomannan-mediated protection in visceral leishmaniasis through up-regulation of toll-like receptor 2 signaling: an immunoprophylactic approach. The Journal of Infectious Diseases. 2010.  202, 145-155. [PubMed]
4. Martin, S., Pahari, S., Sudan, R. and Saha, B.  CD40 signaling in CD8+CD40+ T cells turns on contra-T regulatory cell functions. Journal of Immunology. 2010.  184, 5510-5518. [PubMed]
5. Bhardwaj, S., Srivastava, N., Sudan, R. and Saha, B.  Leishmania interferes with host cell signaling to devise a survival strategy. Journal of Biomedicine & Biotechnology. 2010.  2010, 109189. [PubMed]
6. Khan, A. A., Priya, S. and Saha, B.  IL-2 regulates SEB induced toxic shock syndrome in BALB/c mice. PLoS One. 2009.  4, e8473. [PubMed]
7. Murugaiyan, G. and Saha, B.  Protumor vs antitumor functions of IL-17. Journal of Immunology. 2009.  183, 4169-4175. [PubMed]
8. Wadhone, P., Maiti, M., Agarwal, R., Kamat, V., Martin, S. and Saha, B.  Miltefosine promotes IFN-gamma-dominated anti-leishmanial immune response. Journal of Immunology. 2009.  182, 7146-7154. [PubMed]
9. Rub, A., Dey, R., Jadhav, M., Kamat, R., Chakkaramakkil, S., Majumdar, S., Mukhopadhyaya, R. and Saha, B.  Cholesterol depletion associated with Leishmania major infection alters macrophage CD40 signalosome composition and effector function. Nature Immunology. 2009.  10, 273-280. [PubMed]
10. Khan, A. A., Martin, S. and Saha, B.  SEB-induced signaling in macrophages leads to biphasic TNF-alpha. Journal of Leukocyte Biology. 2008.  83, 1363-1369. [PubMed]
11. Gupta, S., Boppana, R., Mishra, G. C., Saha, B. and Mitra, D.  Interleukin-12 is necessary for the priming of CD4+ T cells required during the elicitation of HIV-1 gp120-specific cytotoxic T-lymphocyte function. Immunology. 2008.  124, 553-561. [PubMed]
12. Gupta, S., Boppana, R., Mishra, G. C., Saha, B. and Mitra, D.  HIV-1 Tat suppresses gp120-specific T cell response in IL-10-dependent manner. Journal of Immunology. 2008.  180, 79-88. [PubMed]
13. Murugaiyan, G., Martin, S. and Saha, B.  CD40-induced countercurrent conduits for tumor escape or elimination? Trends in Immunology. 2007.  28, 467-473. [PubMed]
14. Dey, R., Khan, S. and Saha, B.  A novel functional approach toward identifying definitive drug targets. Current Medicinal Chemistry. 2007.  14, 2380-2392. [PubMed]
15. Remedios, R., Huilgol, D., Saha, B., Hari, P., Bhatnagar, L., Kowalczyk, T., Hevner, R. F., Suda, Y., Aizawa, S., Ohshima, T., Stoykova, A. and Tole, S.  A stream of cells migrating from the caudal telencephalon reveals a link between the amygdala and neocortex. Nature Neuroscience. 2007.  10, 1141-1150. [PubMed]
16. Dey, R., Khan, S., Pahari, S., Srivastava, N., Jadhav, M. and Saha, B.  Functional paradox in host-pathogen interaction dictates the fate of parasites. Future Microbiology. 2007.  2, 425-437. [PubMed]
17. Saha, B., Hari, P., Huilgol, D. and Tole, S.  Dual role for LIM-homeodomain gene Lhx2 in the formation of the lateral olfactory tract. The Journal of Neuroscience. 2007.  27, 2290-2297. [PubMed]
18. Murugaiyan, G., Agrawal, R., Mishra, G. C., Mitra, D. and Saha, B.  Differential CD40/CD40L expression results in counteracting antitumor immune responses. Journal of Immunology. 2007.  178, 2047-2055. [PubMed]
19. Majumder, N., Dey, R., Mathur, R. K., Datta, S., Maitra, M., Ghosh, S., Saha, B. and Majumdar, S.  An unusual pro-inflammatory role of interleukin-10 induced by arabinosylated lipoarabinomannan in murine peritoneal macrophages. Glycoconjugate Journal. 2006.  23, 675-686. [PubMed]
20. Murugaiyan, G., Agrawal, R., Mishra, G. C., Mitra, D. and Saha, B.  Functional dichotomy in CD40 reciprocally regulates effector T cell functions. Journal of Immunology. 2006.  177, 6642-6649. [PubMed]
21. Bodas, M., Jain, N., Awasthi, A., Martin, S., Penke, L., Dandekar, D., Mitra, D. and Saha, B.  Inhibition of IL-2 induced IL-10 production as a principle of phase-specific immunotherapy. Journal of Immunology. 2006.  177, 4636-4643. [PubMed]
22. Mookerjee, B., Mookerjee, A., Sen, P., Bhaumik, S., Sen, P., Banerjee, S., Naskar, K., Choudhuri, S. K., Saha, B., Raha, S. and Roy, S.  Sodium antimony gluconate induces generation of reactive oxygen species and nitric oxide via phosphoinositide 3-kinase and mitogen-activated protein kinase activation in Leishmania donovani-infected macrophages. Antimicrobial Agents and Chemotherapy. 2006.  50, 1788-1797. [PubMed]
23. Mathur, R. K., Awasthi, A. and Saha, B.  The conundrum of CD40 function: host protection or disease promotion? Trends in Parasitology. 2006.  22, 117-122. [PubMed]
24. Tole, S., Remedios, R., Saha, B. and Stoykova, A.  Selective requirement of Pax6, but not Emx2, in the specification and development of several nuclei of the amygdaloid complex. The Journal of Neuroscience. 2005.  25, 2753-2760. [PubMed]
25. Kaul-Ghanekar, R., Majumdar, S., Jalota, A., Gulati, N., Dubey, N., Saha, B. and Chattopadhyay, S.  Abnormal V(D)J recombination of T cell receptor beta locus in SMAR1 transgenic mice. The Journal of Biological Chemistry. 2005.  280, 9450-9459. [PubMed]
26. Awasthi, A., Mathur, R. K. and Saha, B.  Immune response to Leishmania infection. The Indian Journal of Medical Research. 2004.  119, 238-258. [PubMed]
27. Mathur, R. K., Awasthi, A., Wadhone, P., Ramanamurthy, B. and Saha, B.  Reciprocal CD40 signals through p38MAPK and ERK-1/2 induce counteracting immune responses. Nature Medicine. 2004.  10, 540-544. [PubMed]
28. Vyas, A., Saha, B., Lai, E. and Tole, S.  Paleocortex is specified in mice in which dorsal telencephalic patterning is severely disrupted. The Journal of Comparative Neurology. 2003.  466, 545-553. [PubMed]

 
 
Education 
::
Ph.D.
Member
::
Molecular Immunology Forum
::
Society of Biological Chemists
::
Indian Immunology Society
  Last modified on : Mar 4, 2011
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