INCREDB ID : 168
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Ranju Ralhan, Ph.D.
Professor 
 
All India Institute of Medical Sciences
Department of Biochemistry
Ansari Nagar
New Delhi - 110 029   
 
E-mail: ralhanr@hotmail.com, ralhanr@rediffmail.com
Phone: +91-11-26593478, Extn. 3478
Fax: +91-11-26588641
 
Positions Held:
Position Affiliation Time Period
Professor All India Institute of Medical Sciences, New Delhi, India 2003-Present
Additional Professor All India Institute of Medical Sciences, New Delhi, India 1995-2003
Associate Professor All India Institute of Medical Sciences, New Delhi, India 1991-1995
Assistant Professor All India Institute of Medical Sciences, New Delhi, India 1987-1991
CSIR, Pool Officer All India Institute of Medical Sciences, New Delhi, India 1986-1987
Fogarty Postdoctoral Fellow National Cancer Institute, National Institutes of Health, MD, USA 1984-1986
Research Officer National Institute of Immunology, New Delhi, India 1982-1984
CSIR, Post Doctoral Fellow Cancer Research Institute, Tata Memorial Centre, Mumbai, India 1980-1981
 
Area of Specialization:
Oncology
Research Summary:
Establishment of experimental model for oral cancer
Identification of molecular markers for early diagnosis of oral and esophageal cancer
Identification of novel differentially expressed genes in oral and esophageal cancer
Developed immunodiagnostic assay for serological analysis of p53
 
Publications:
1. Macha, M. A., Matta, A., Chauhan, S. S., Siu, K. W. and Ralhan, R.  Guggulsterone (GS) Inhibits Smokeless Tobacco and Nicotine Induced NF{kappa}B and STAT3 pathways in Head and Neck Cancer cells. Carcinogenesis. 2010. [PubMed]
2. Ralhan, R., He, H. C., So, A. K., Tripathi, S. C., Kumar, M., Hasan, M. R., Kaur, J., Kashat, L., MacMillan, C., Chauhan, S. S., Freeman, J. L. and Walfish, P. G.  Nuclear and cytoplasmic accumulation of Ep-ICD is frequently detected in human epithelial cancers. PLoS One 2010.  5, e14130. [PubMed]
3. Macha, M. A., Matta, A., Chauhan, S., Siu, K. M. and Ralhan, R.  14-3-3 zeta is a molecular target in guggulsterone induced apoptosis in Head and Neck cancer cells. BMC Cancer. 2010.  10, 655. [PubMed]
4. Matta, A., Ralhan, R., DeSouza, L. V. and Siu, K. W.  Mass spectrometry-based clinical proteomics: head-and-neck cancer biomarkers and drug-targets discovery. Mass spectrometry Reviews. 2010.  29, 945-961. [PubMed]
5. Matta, A., DeSouza, L. V., Ralhan, R. and Siu, K. W.  Small interfering RNA targeting 14-3-3zeta increases efficacy of chemotherapeutic agents in head and neck cancer cells. Molecular Cancer Therapeutics. 2010.  9, 2676-2688. [PubMed]
6. Kausar, T., Sharma, R., Hasan, M. R., Tripathi, S. C., Saraya, A., Chattopadhyay, T. K., Gupta, S. D. and Ralhan, R.  Clinical significance of GPR56, transglutaminase 2, and NF-kappaB in esophageal squamous cell carcinoma. Cancer Investigation. 2011.  29, 42-48. [PubMed]
7. Kashat, L., So, A. K., Masui, O., Wang, X. S., Cao, J., Meng, X., Macmillan, C., Ailles, L. E., Siu, K. W., Ralhan, R. and Walfish, P. G.  Secretome-based identification and characterization of potential biomarkers in thyroid cancer. Journal of Proteome Research. 2010.  9, 5757-5769. [PubMed]
8. Sharma, G., Mirza, S., Parshad, R., Srivastava, A., Gupta, S. D., Pandya, P. and Ralhan, R.  Clinical significance of Maspin promoter methylation and loss of its protein expression in invasive ductal breast carcinoma: correlation with VEGF-A and MTA1 expression. Tumour Biology. 2011.  32, 23-32. [PubMed]
9. Tripathi, S. C., Matta, A., Kaur, J., Grigull, J., Chauhan, S. S., Thakar, A., Shukla, N. K., Duggal, R., DattaGupta, S., Ralhan, R. and Siu, K. W.  Nuclear S100A7 is associated with poor prognosis in head and neck cancer. PLoS One. 2010.  5, e11939. [PubMed]
10. Macha, M. A., Matta, A., Kaur, J., Chauhan, S. S., Thakar, A., Shukla, N. K., Gupta, S. D. and Ralhan, R.  Prognostic significance of nuclear pSTAT3 in oral cancer. Head & Neck. 2010.  [PubMed]
11. Ralhan, R., Cao, J., Lim, T., Macmillan, C., Freeman, J. L. and Walfish, P. G.  EpCAM nuclear localization identifies aggressive thyroid cancer and is a marker for poor prognosis. BMC Cancer. 2010.  10, 331. [PubMed]
12. Kaur, J., Demokan, S., Tripathi, S. C., Macha, M. A., Begum, S., Califano, J. A. and Ralhan, R.  Promoter hypermethylation in Indian primary oral squamous cell carcinoma. International Journal of Cancer. 2010. 127, 2367-2373. [PubMed]
13. Sharma, G., Mirza, S., Parshad, R., Srivastava, A., Gupta, S. D., Pandya, P. and Ralhan, R.  Clinical significance of promoter hypermethylation of DNA repair genes in tumor and serum DNA in invasive ductal breast carcinoma patients. Life Sciences. 2010.  87, 83-91. [PubMed]
14. Mirza, S., Sharma, G., Pandya, P. and Ralhan, R.  Demethylating agent 5-aza-2-deoxycytidine enhances susceptibility of breast cancer cells to anticancer agents. Molecular and Cellular Biochemistry. 2010.  342, 101-109. [PubMed]
15. Kaur, J., Sawhney, M., Dattagupta, S., Shukla, N. K., Srivastava, A. and Ralhan, R.  Clinical significance of phosphatidyl inositol synthase overexpression in oral cancer. BMC Cancer. 2010.  10, 168. [PubMed]
16. Macha, M. A., Matta, A., Sriram, U., Thakkar, A., Shukla, N. K., Datta, G. and Ralhan, R.  Clinical significance of TC21 overexpression in oral cancer. Journal of Oral Pathology & Medicine. 2010.  39, 477-485. [PubMed]
17. Mirza, S., Sharma, G., Parshad, R., Srivastava, A., Gupta, S. D. and Ralhan, R.  Clinical significance of Stratifin, ERalpha and PR promoter methylation in tumor and serum DNA in Indian breast cancer patients. Clinical Biochemistry. 2010.  43, 380-386. [PubMed]
18. Prasad, C. P., Rath, G., Mathur, S., Bhatnagar, D. and Ralhan, R.  Expression analysis of maspin in invasive ductal carcinoma of breast and modulation of its expression by curcumin in breast cancer cell lines. Chemico-Biological Interactions. 2010.  183, 455-461. [PubMed]
19. Sharma, G., Mirza, S., Yang, Y. H., Parshad, R., Hazrah, P., Datta, G. and Ralhan, R.  Prognostic relevance of promoter hypermethylation of multiple genes in breast cancer patients. Cellular Oncology. 2009.  31, 487-500. [PubMed]
20. Tripathi, R., Rath, G., Ralhan, R., Saxena, S. and Salhan, S.  Soluble and membranous vascular endothelial growth factor receptor-2 in pregnancies complicated by pre-eclampsia. Yonsei Medical Journal. 2009.  50, 656-666. [PubMed]
21. Sharma, G., Mirza, S., Parshad, R., Srivastava, A., Datta, G., Pandya, P. and Ralhan, R.  CpG hypomethylation of MDR1 gene in tumor and serum of invasive ductal breast carcinoma patients. Clinical Biochemistry. 2010.  43, 373-379. [PubMed]
22. Prasad, C. P., Rath, G., Mathur, S., Bhatnagar, D., Parshad, R. and Ralhan, R.  Expression analysis of E-cadherin, Slug and GSK3beta in invasive ductal carcinoma of breast. BMC Cancer. 2009.  9, 325. [PubMed]
23. Kausar, T., Ahsan, A., Hasan, M. R., Lin, L., Beer, D. G. and Ralhan, R.  Sperm protein 17 is a novel marker for predicting cisplatin response in esophageal squamous cancer cell lines. International Journal of Cancer. 2010.  126, 1494-1503. [PubMed]
24. Yadav, B. K., Kaur, J., Srivastava, A. and Ralhan, R.  Effect of polymorphisms in XRCC1, CCND1 and GSTM1 and tobacco exposure as risk modifier for oral leukoplakia. The International Journal of Biological Markers. 2009.  24, 90-98. [PubMed]
25. Prasad, C. P., Rath, G., Mathur, S., Bhatnagar, D. and Ralhan, R.  Potent growth suppressive activity of curcumin in human breast cancer cells: Modulation of Wnt/beta-catenin signaling. Chemico-Biological Interactions. 2009.  181, 263-271. [PubMed]
26. Matta, A., Tripathi, S. C., DeSouza, L. V., Grigull, J., Kaur, J., Chauhan, S. S., Srivastava, A., Thakar, A., Shukla, N. K., Duggal, R., DattaGupta, S., Ralhan, R. and Michael, S. i. u.  Heterogeneous ribonucleoprotein K is a marker of oral leukoplakia and correlates with poor prognosis of squamous cell carcinoma. International Journal of Cancer. 2009.  125, 1398-1406. [PubMed]
27. Ralhan, R., Pandey, M. K. and Aggarwal, B. B.  Nuclear factor-kappa B links carcinogenic and chemopreventive agents. Frontiers in Bioscience. 2009.  1, 45-60. [PubMed]
28. Sinha, P., Bahadur, S., Thakar, A., Matta, A., Macha, M., Ralhan, R. and Gupta, S. D.  Significance of promoter hypermethylation of p16 gene for margin assessment in carcinoma tongue. Head & Neck. 2009.  31, 1423-1430. [PubMed]
29. Matta, A. and Ralhan, R.  Overview of current and future biologically based targeted therapies in head and neck squamous cell carcinoma. Head & Neck Oncology. 2009.  1, 6. [PubMed]
30. Bajpai, U., Sharma, R., Kausar, T., Dattagupta, S., Chattopadhayay, T. K. and Ralhan, R.  Clinical significance of 14-3-3 zeta in human esophageal cancer. The International Journal of Biological Markers. 2008.  23, 231-237. [PubMed]
31. Sawhney, M., Matta, A., Macha, M. A., Kaur, J., DattaGupta, S., Shukla, N. K. and Ralhan, R.  Cytoplasmic accumulation of activated leukocyte cell adhesion molecule is a predictor of disease progression and reduced survival in oral cancer patients. International Journal of Cancer. 2009.  124, 2098-2105. [PubMed]
32. Ralhan, R., Desouza, L. V., Matta, A., Chandra, T., Ghanny, S., Dattagupta, S., Thakar, A., Chauhan, S. S. and Siu, K. W.  iTRAQ-multidimensional liquid chromatography and tandem mass spectrometry-based identification of potential biomarkers of oral epithelial dysplasia and novel networks between inflammation and premalignancy. Journal of Proteome Research. 2009.  8, 300-309. [PubMed]
33. Prasad, C. P., Mirza, S., Sharma, G., Prashad, R., DattaGupta, S., Rath, G. and Ralhan, R.  Epigenetic alterations of CDH1 and APC genes: relationship with activation of Wnt/beta-catenin pathway in invasive ductal carcinoma of breast. Life Sciences. 2008.  83, 318-325. [PubMed]
34. Pokharel, H. P., Bhatla, N., Kriplani, A., Mukhopadhyay, A., Srivastava, A. and Ralhan, R.  Evaluation of endometrial changes and p53 expression in tamoxifen treated women: comparison of various methods. Kathmandu University Medical Journal. 2006.  4, 145-151. [PubMed]
35. Bagadi, S. A., Prasad, C. P., Kaur, J., Srivastava, A., Prashad, R., Gupta, S. D. and Ralhan, R.  Clinical significance of promoter hypermethylation of RASSF1A, RARbeta2, BRCA1 and HOXA5 in breast cancers of Indian patients. Life Sciences. 2008.  82, 1288-1292. [PubMed]
35. Ahn, K. S., Sethi, G., Sung, B., Goel, A., Ralhan, R. and Aggarwal, B. B.  Guggulsterone, a farnesoid X receptor antagonist, inhibits constitutive and inducible STAT3 activation through induction of a protein tyrosine phosphatase SHP-1. Cancer research. 2008.  68, 4406-4415. [PubMed]
36. Keimling, M., Kaur, J., Bagadi, S. A., Kreienberg, R., Wiesmuller, L. and Ralhan, R.  A sensitive test for the detection of specific DSB repair defects in primary cells from breast cancer specimens. International journal of cancer. Journal international du cancer. 2008.  123, 730-736. [PubMed]
37. Matta, A., DeSouza, L. V., Shukla, N. K., Gupta, S. D., Ralhan, R. and Siu, K. W.  Prognostic significance of head-and-neck cancer biomarkers previously discovered and identified using iTRAQ-labeling and multidimensional liquid chromatography-tandem mass spectrometry. Journal of proteome research. 2008.  7, 2078-2087. [PubMed]
38. Ralhan, R., Desouza, L. V., Matta, A., Chandra, T., Ghanny, S., Datta, G., Bahadur, S. and Siu, K. W.  Discovery and verification of head-and-neck cancer biomarkers by differential protein expression analysis using iTRAQ labeling, multidimensional liquid chromatography, and tandem mass spectrometry. Molecular & cellular proteomics : MCP. 2008.  7, 1162-1173. [PubMed]
39. Prasad, C. P., Gupta, S. D., Rath, G. and Ralhan, R.  Wnt signaling pathway in invasive ductal carcinoma of the breast: relationship between beta-catenin, dishevelled and cyclin D1 expression. Oncology. 2007.  73, 112-117. [PubMed]
40. Shukla, S., Mirza, S., Sharma, G., Parshad, R., Gupta, S. D. and Ralhan, R.  Detection of RASSF1A and RARbeta hypermethylation in serum DNA from breast cancer patients. Epigenetics : official journal of the DNA Methylation Society. 2006.  1, 88-93. [PubMed]
41. Raju, B., Kaur, J. and Ralhan, R.  Establishment and characterisation of two novel breast cancer cell lines. Cell biology international. 2008.  32, 55-65. [PubMed]
42. Matta, A., Bahadur, S., Duggal, R., Gupta, S. D. and Ralhan, R.  Over-expression of 14-3-3zeta is an early event in oral cancer. BMC cancer. 2007.  7, 169. [PubMed]
43. Mirza, S., Sharma, G., Prasad, C. P., Parshad, R., Srivastava, A., Gupta, S. D. and Ralhan, R.  Promoter hypermethylation of TMS1, BRCA1, ERalpha and PRB in serum and tumor DNA of invasive ductal breast carcinoma patients. Life sciences. 2007.  81, 280-287. [PubMed]
44. Sharma, G., Mirza, S., Prasad, C. P., Srivastava, A., Gupta, S. D. and Ralhan, R.  Promoter hypermethylation of p16INK4A, p14ARF, CyclinD2 and Slit2 in serum and tumor DNA from breast cancer patients. Life sciences. 2007.  80, 1873-1881. [PubMed]
45. Sawhney, M., Rohatgi, N., Kaur, J., Shishodia, S., Sethi, G., Gupta, S. D., Deo, S. V., Shukla, N. K., Aggarwal, B. B. and Ralhan, R.  Expression of NF-kappaB parallels COX-2 expression in oral precancer and cancer: association with smokeless tobacco. International journal of cancer. Journal international du cancer. 2007.  120, 2545-2556. [PubMed]
46. Warnakulasuriya, K. A. and Ralhan, R.  Clinical, pathological, cellular and molecular lesions caused by oral smokeless tobacco--a review. Journal of oral pathology & medicine : official publication of the International. 2007.  36, 63-77. [PubMed]
47. Gupta, G., Sharma, R., Chattopadhyay, T. K., Gupta, S. D. and Ralhan, R.  Clinical significance of sperm protein 17 expression and immunogenicity in esophageal cancer. International journal of cancer. Journal international du cancer. 2007.  120, 1739-1747. [PubMed]
48. Bagadi, S. A., Prasad, C. P., Srivastava, A., Prashad, R., Gupta, S. D. and Ralhan, R.  Frequent loss of Dab2 protein and infrequent promoter hypermethylation in breast cancer. Breast cancer research and treatment. 2007.  104, 277-286. [PubMed]
49. Kumar, A., Chatopadhyay, T., Raziuddin, M. and Ralhan, R.  Discovery of deregulation of zinc homeostasis and its associated genes in esophageal squamous cell carcinoma using cDNA microarray. International journal of cancer. Journal international du cancer. 2007.  120, 230-242. [PubMed]
50. Sawhney, M., Rohatgi, N., Kaur, J., Gupta, S. D., Deo, S. V., Shukla, N. K. and Ralhan, R.  MGMT expression in oral precancerous and cancerous lesions: correlation with progression, nodal metastasis and poor prognosis. Oral oncology. 2007.  43, 515-522. [PubMed]
51. Sharma, C., Kaur, J., Shishodia, S., Aggarwal, B. B. and Ralhan, R.  Curcumin down regulates smokeless tobacco-induced NF-kappaB activation and COX-2 expression in human oral premalignant and cancer cells. Toxicology. 2006.  228, 1-15. [PubMed]
52. Ralhan, R., Kaur, J., Kreienberg, R. and Wiesmuller, L.  Links between DNA double strand break repair and breast cancer: accumulating evidence from both familial and nonfamilial cases. Cancer letters. 2007.  248, 1-17. [PubMed]
53. Rohatgi, N., Matta, A., Kaur, J., Srivastava, A. and Ralhan, R.  Novel molecular targets of smokeless tobacco (khaini) in cell culture from oral hyperplasia. Toxicology. 2006.  224, 1-13. [PubMed]
54. Verma, A., Matta, A., Shukla, N. K., Deo, S. V., Gupta, S. D. and Ralhan, R.  Clinical significance of mannose-binding lectin-associated serine protease-2 expression in esophageal squamous cell carcinoma. International journal of cancer. Journal international du cancer. 2006.  118, 2930-2935. [PubMed]
55. Ralhan, R., Chakravarti, N., Kaur, J., Sharma, C., Kumar, A., Mathur, M., Bahadur, S., Shukla, N. K. and Deo, S. V.  Clinical significance of altered expression of retinoid receptors in oral precancerous and cancerous lesions: relationship with cell cycle regulators. International journal of cancer. Journal international du cancer. 2006.  118, 1077-1089. [PubMed]
56. Sharma, R., Sud, N., Chattopadhyay, T. K. and Ralhan, R.  TC21/R-Ras2 upregulation in esophageal tumorigenesis: potential diagnostic implications. Oncology. 2005.  69, 10-18. [PubMed]
57. Verma, A., Shukla, N. K., Deo, S. V., Gupta, S. D. and Ralhan, R.  MEMD/ALCAM: a potential marker for tumor invasion and nodal metastasis in esophageal squamous cell carcinoma. Oncology. 2005.  68, 462-470. [PubMed]
58. Soni, S., Kaur, J., Kumar, A., Chakravarti, N., Mathur, M., Bahadur, S., Shukla, N. K., Deo, S. V. and Ralhan, R.  Alterations of rb pathway components are frequent events in patients with oral epithelial dysplasia and predict clinical outcome in patients with squamous cell carcinoma. Oncology. 2005.  68, 314-325. [PubMed]
59. Rohatgi, N., Kaur, J., Srivastava, A. and Ralhan, R.  Smokeless tobacco (khaini) extracts modulate gene expression in epithelial cell culture from an oral hyperplasia. Oral oncology. 2005.  41, 806-820. [PubMed]
60. Sud, N., Sharma, R., Ray, R., Chattopadhyay, T. K. and Ralhan, R.  Differential expression of G-protein coupled receptor 56 in human esophageal squamous cell carcinoma. Cancer letters. 2006.  233, 265-270. [PubMed]
61. Arora, S., Kaur, J., Sharma, C., Mathur, M., Bahadur, S., Shukla, N. K., Deo, S. V. and Ralhan, R.  Stromelysin 3, Ets-1, and vascular endothelial growth factor expression in oral precancerous and cancerous lesions: correlation with microvessel density, progression, and prognosis. Clinical cancer research : an official journal of the American Association for. 2005.  11, 2272-2284. [PubMed]
62. Arora, S., Matta, A., Shukla, N. K., Deo, S. V. and Ralhan, R.  Identification of differentially expressed genes in oral squamous cell carcinoma. Molecular carcinogenesis. 2005.  42, 97-108. [PubMed]
63. Sharma, R., Chattopadhyay, T. K., Mathur, M. and Ralhan, R.  Prognostic significance of stromelysin-3 and tissue inhibitor of matrix metalloproteinase-2 in esophageal cancer. Oncology. 2004.  67, 300-309. [PubMed]
64. Sud, N., Sharma, R., Ray, R., Chattopadhyay, T. and Ralhan, R.  Differential expression of beta mannosidase in human esophageal cancer. International journal of cancer. Journal international du cancer. 2004.  112, 905-907. [PubMed]
65. Kumar, A., Kaur, J., Chattopadhyay, T. K., Mathur, M. and Ralhan, R.  Differential expression of retinoic acid receptors in normal and malignant esophageal tissues. Journal of experimental therapeutics & oncology. 2004.  4, 1-8. [PubMed]
66. Kaur, J., Chakravarti, N., Mathur, M., Srivastava, A. and Ralhan, R.  Alterations in expression of retinoid receptor beta and p53 in oral submucous fibrosis. Oral diseases. 2004.  10, 201-206. [PubMed]
67. Samantaray, S., Sharma, R., Chattopadhyaya, T. K., Gupta, S. D. and Ralhan, R.  Increased expression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma. Journal of cancer research and clinical oncology. 2004.  130, 37-44. [PubMed]
68. Kaur, J. and Ralhan, R.  Establishment and characterization of a cell line from smokeless tobacco associated oral squamous cell carcinoma. Oral oncology. 2003.  39, 806-820. [PubMed]
69. Soni, S., Mathur, M., Shukla, N. K., Deo, S. V. and Ralhan, R.  Stromelysin-3 expression is an early event in human oral tumorigenesis. International journal of cancer. 2003.  107, 309-316. [PubMed]
70. Mukherjee, T., Kumar, A., Mathur, M., Chattopadhyay, T. K. and Ralhan, R.  Ets-1 and VEGF expression correlates with tumor angiogenesis, lymph node metastasis, and patient survival in esophageal squamous cell carcinoma. Journal of cancer research and clinical oncology. 2003.  129, 430-436. [PubMed]
71. Ralhan, R. and Kaur, J.  Retinoids as chemopreventive agents. Journal of biological regulators and homeostatic agents. 2003.  17, 66-91. [PubMed]
72. Sharma, R., Samantaray, S., Shukla, N. K. and Ralhan, R.  Transcriptional gene expression profile of human esophageal squamous cell carcinoma. Genomics. 2003.  81, 481-488. [PubMed]
73. Srivastava, A., Ralhan, R. and Kaur, J.  Angiogenesis in cutaneous melanoma: pathogenesis and clinical implications. Microscopy research and technique. 2003.  60, 208-224. [PubMed]
74. Chakravarti, N., Mathur, M., Bahadur, S., Kumar, S. and Ralhan, R.  Retinoic acid receptor-alpha as a prognostic indicator in oral squamous cell carcinoma. International journal of cancer. 2003.  103, 544-549. [PubMed]
75. Mathew, R., Khanna, R., Kumar, R., Mathur, M., Shukla, N. K. and Ralhan, R.  Stromelysin-2 overexpression in human esophageal squamous cell carcinoma: potential clinical implications. Cancer detection and prevention. 2002.  26, 222-228. [PubMed]
76. Pande, P., Soni, S., Kaur, J., Agarwal, S., Mathur, M., Shukla, N. K. and Ralhan, R.  Prognostic factors in betel and tobacco related oral cancer. Oral oncology. 2002.  38, 491-499. [PubMed]
77. Soni, S., Pande, P., Shukla, N. K. and Ralhan, R.  Coexpression of Ets-1 and p53 in oral carcinomas is associated with P-glycoprotein expression and poor prognosis. Journal of cancer research and clinical oncology. 2002.  128, 336-342. [PubMed]
78. Mathew, R., Arora, S., Khanna, R., Mathur, M., Shukla, N. K. and Ralhan, R.  Alterations in p53 and pRb pathways and their prognostic significance in oesophageal cancer. European journal of cancer. 2002.  38, 832-841. [PubMed]
79. Pande, P., Soni, S., Chakravarti, N., Mathur, M., Shukla, N. K. and Ralhan, R.  Prognostic impact of Ets-1 overexpression in betel and tobacco related oral cancer. Cancer detection and prevention. 2001.  25, 496-501. [PubMed]
80. Arora, S., Mathew, R., Mathur, M., Chattopadhayay, T. K. and Ralhan, R.  Alterations in MDM2 expression in esophageal squamous cell carcinoma: relationship with p53 status. Pathology oncology research : POR. 2001.  7, 203-208. [PubMed]
81. Mathew, R., Arora, S., Mathur, M., Chattopadhyay, T. K. and Ralhan, R.  Esophageal squamous cell carcinomas with DNA replication errors (RER+) are associated with p16/pRb loss and wild-type p53. Journal of cancer research and clinical oncology. 2001.  127, 603-612. [PubMed]
82. Mathew, R., Arora, S., Khanna, R., Shukla, N. K., Mathur, M. and Ralhan, R.  Alterations in cyclin D1 expression in esophageal squamous cell carcinoma in the Indian population. Journal of cancer research and clinical oncology. 2001.  127, 251-257. [PubMed]
83. Kaur, J., Rao, M., Chakravarti, N., Mathur, M., Shukla, N. K., Sanwal, B. D. and Ralhan, R.  Co-expression of colligin and collagen in oral submucous fibrosis: plausible role in pathogenesis. Oral oncology. 2001.  37, 282-287. [PubMed]
84. Ralhan, R., Agarwal, S., Nath, N., Mathur, M., Wasylyk, B. and Srivastava, A.  Correlation between p53 gene mutations and circulating antibodies in betel- and tobacco-consuming North Indian population. Oral oncology. 2001.  37, 243-250. [PubMed]
85. Chakravarti, N., Mathur, M., Bahadur, S., Shukla, N. K., Rochette-Egly, C. and Ralhan, R.  Expression of RARalpha and RARbeta in human oral potentially malignant and neoplastic lesions. International journal of cancer. Journal international du cancer. 2001.  91, 27-31. [PubMed]
86. Ralhan, R., Mathew, R., Arora, S., Bahl, R., Shukla, N. K. and Mathur, M.  Frequent alterations in the expression of tumor suppressor genes p16INK4A and pRb in esophageal squamous cell carcinoma in the Indian population. Journal of cancer research and clinical oncology. 2000.  126, 655-660. [PubMed]
87. Ralhan, R., Sandhya, A., Meera, M., Bohdan, W. and Nootan, S. K.  Induction of MDM2-P2 transcripts correlates with stabilized wild-type p53 in betel- and tobacco-related human oral cancer. The American journal of pathology. 2000.  157, 587-596. [PubMed]
88. Ralhan, R., Agarwal, S., Mathur, M., Wasylyk, B. and Srivastava, A.  Association between polymorphism in p21(Waf1/Cip1) cyclin-dependent kinase inhibitor gene and human oral cancer. Clinical cancer research : an official journal of the American Association for. 2000.  6, 2440-2447. [PubMed]
89. Salotra, P., Ralhan, R. and Sreenivas, G.  Heat-stress induced modulation of protein phosphorylation in virulent promastigotes of Leishmania donovani. The international journal of biochemistry & cell biology. 2000.  32, 309-316. [PubMed]
90. Ralhan, R., Arora, S., Chattopadhyay, T. K., Shukla, N. K. and Mathur, M.  Circulating p53 antibodies, p53 gene mutational profile and product accumulation in esophageal squamous-cell carcinoma in India. International journal of cancer. Journal international du cancer. 2000.  85, 791-795. [PubMed]
91. Sengupta, S., Ralhan, R. and Wasylyk, B.  Tumour regression in a ligand inducible manner mediated by a chimeric tumour suppressor derived from p53. Oncogene. 2000.  19, 337-350. [PubMed]
92. Bahl, R., Arora, S., Nath, N., Mathur, M., Shukla, N. K. and Ralhan, R.  Novel polymorphism in p21(waf1/cip1) cyclin dependent kinase inhibitor gene: association with human esophageal cancer. Oncogene. 2000.  19, 323-328. [PubMed]
93. Kaur, J., Kaur, J. and Ralhan, R.  Induction of apoptosis by abrogation of HSP70 expression in human oral cancer cells. International journal of cancer. Journal international du cancer. 2000.  85, 1-5. [PubMed]
94. Pande, P., Mathur, M., Shukla, N. K. and Ralhan, R.  Ets-1: a plausible marker of invasive potential and lymph node metastasis in human oral squamous cell carcinomas. The Journal of pathology. 1999.  189, 40-45. [PubMed]
95. Agarwal, S., Mathur, M., Srivastava, A. and Ralhan, R.  MDM2/p53 co-expression in oral premalignant and malignant lesions: potential prognostic implications. Oral oncology. 1999.  35, 209-216. [PubMed]
96. Ralhan, R., Swain, R. K., Agarwal, S., Kaur, J., Nath, N., Sarkar, G., Mathur, M. and Shukla, N. K.  P-glycoprotein is positively correlated with p53 in human oral pre-malignant and malignant lesions and is associated with poor prognosis. International journal of cancer. Journal international du cancer. 1999.  84, 80-85. [PubMed]
97. Kaur, J., Srivastava, A. and Ralhan, R.  Expression of 70-kDa heat shock protein in oral lesions: marker of biological stress or pathogenicity. Oral oncology. 1998.  34, 496-501. [PubMed]
98. Pande, P., Mathur, M., Shukla, N. K. and Ralhan, R.  pRb and p16 protein alterations in human oral tumorigenesis. Oral oncology. 1998.  34, 396-403. [PubMed]
99. Agarwal, S., Mathur, M., Shukla, N. K. and Ralhan, R.  Expression of cyclin dependent kinase inhibitor p21waf1/cip1 in premalignant and malignant oral lesions: relationship with p53 status. Oral oncology. 1998.  34, 353-360. [PubMed]
100. Gaur, D., Arora, S., Mathur, M., Nath, N., Chattopadhaya, T. K. and Ralhan, R.  High prevalence of p53 gene alterations and protein overexpression in human esophageal cancer: correlation with dietary risk factors in India. Clinical cancer research. 1997.  3, 2129-2136. [PubMed]
101. Ralhan, R., Nath, N., Agarwal, S., Mathur, M., Wasylyk, B. and Shukla, N. K.  Circulating p53 antibodies as early markers of oral cancer: correlation with p53 alterations. Clinical cancer research. 1998.  4, 2147-2152. [PubMed]
102. Kaur, J., Srivastava, A. and Ralhan, R.  Prognostic significance of p53 protein overexpression in betel- and tobacco-related oral oncogenesis. International journal of cancer. Journal international du cancer. 1998.  79, 370-375. [PubMed]
103. Kaur, J., Das, S. N., Srivastava, A. and Ralhan, R.  Cell surface expression of 70 kDa heat shock protein in human oral dysplasia and squamous cell carcinoma: correlation with clinicopathological features. Oral oncology. 1998.  34, 93-98. [PubMed]
104. Sharma, D., Chelvi, T. P., Kaur, J. and Ralhan, R.  Thermosensitive liposomal taxol formulation: heat-mediated targeted drug delivery in murine melanoma. Melanoma research. 1998.  8, 240-244. [PubMed]
105. Kaur, J., Srivastava, A. and Ralhan, R.  Serum p53 antibodies in patients with oral lesions: correlation with p53/HSP70 complexes. International journal of cancer. 1997.  74, 609-613. [PubMed]
106. Ralhan, R., Narayan, M., Salotra, P., Shukla, N. K. and Chauhan, S. S.  Evaluation of P-glycoprotein expression in human oral oncogenesis: correlation with clinicopathological features. International journal of cancer. Journal international du cancer. 1997.  72, 728-734. [PubMed]
107. Sarkar, G., Nath, N., Shukla, N. K. and Ralhan, R.  Glutathione S-transferase pi expression in matched human normal and malignant oral mucosa. Oral oncology. 1997.  33, 74-81. [PubMed]
108. Jain, V., Das, S. N., Luthra, K., Shukla, N. K. and Ralhan, R.  Differential expression of multidrug resistance gene product, P-glycoprotein, in normal, dysplastic and malignant oral mucosa in India. International journal of cancer. Journal international du cancer. 1997.  74, 128-133. [PubMed]
109. Chelvi, T. P. and Ralhan, R.  Hyperthermia potentiates antitumor effect of thermosensitive-liposome-encapsulated melphalan and radiation in murine melanoma. Tumour biology : the journal of the International Society for Oncodevelopmental. 1997.  18, 250-260. [PubMed]
110. Sharma, D., Chelvi, T. P., Kaur, J., Chakravorty, K., De, T. K., Maitra, A. and Ralhan, R.  Novel Taxol formulation: polyvinylpyrrolidone nanoparticle-encapsulated Taxol for drug delivery in cancer therapy. Oncology research. 1996.  8, 281-286. [PubMed]
111. Kaur, J., Srivastava, A. and Ralhan, R.  p53-HSP70 complexes in oral dysplasia and cancer: potential prognostic implications. European journal of cancer. Part B, Oral oncology. 1996.  32B, 45-49. [PubMed]
112. Kaur, J. and Ralhan, R.  Differential expression of 70-kDa heat shock-protein in human oral tumorigenesis. International journal of cancer. 1995.  63, 774-779. [PubMed]
113. Ralhan, R. and Kaur, J.  Differential expression of Mr 70,000 heat shock protein in normal, premalignant, and malignant human uterine cervix. Clinical cancer research. 1995.  1, 1217-1222. [PubMed]
114. Chelvi, P. T., Jain, S. K. and Ralhan, R.  Heat-mediated selective delivery of liposome-associated melphalan in murine melanoma. Melanoma research. 1995.  5, 321-326. [PubMed]
115. Chelvi, T. P. and Ralhan, R.  Designing of thermosensitive liposomes from natural lipids for multimodality cancer therapy. International journal of hyperthermia. 1995.  11, 685-695. [PubMed]
116. Ralhan, R., Kaur, J., Chelvi, T., Singh, S. P. and Zeba, H.  Heat stress stimulates high affinity GTPase in cervical carcinoma cells. The international journal of biochemistry & cell biology. 1995.  27, 263-269. [PubMed]
117. Chelvi, T. P., Jain, S. K. and Ralhan, R.  Hyperthermia-mediated targeted delivery of thermosensitive liposome-encapsulated melphalan in murine tumors. Oncology research. 1995.  7, 393-398. [PubMed]
118. Salotra, P., Chauhan, D., Ralhan, R. and Bhatnagar, R.  Tumour necrosis factor-alpha induces preferential expression of stress proteins in virulent promastigotes of Leishmania donovani. Immunology letters. 1995.  44, 1-5. [PubMed]
119. Kaur, J., Srivastava, A. and Ralhan, R.  Overexpression of p53 protein in betel- and tobacco-related human oral dysplasia and squamous-cell carcinoma in India. International journal of cancer.  1994.  58, 340-345. [PubMed]
120. Salotra, P., Ralhan, R. and Bhatnagar, R.  Differential expression of stress proteins in virulent and attenuated promastigotes of Leishmania donovani. Biochemistry and molecular biology international. 1994.  33, 691-697. [PubMed]
121. Roy, A., Agarwal, A. and Ralhan, R.  Anti-arabinogalactan IgM/IgG ratio: a screening index for leprosy patients. Indian journal of leprosy. 1990.  62, 435-442. [PubMed]
122. Bhatia, M., Ralhan, R. and Sharma, S. K.  Ascorbate inhibits specific binding of etorphine and low Km GTPase in NG108-15 hybrid cells. Indian journal of biochemistry & biophysics. 1988.  25, 699-702. [PubMed]
123. Sharma, S. K., Bhatia, M. and Ralhan, R.  Mechanism of development of tolerance and dependence to opioids in neuroblastoma x glioma hybrid cells and mice. NIDA research monograph. 1988.  87, 157-166. [PubMed]
124. Johnson, G. S. and Ralhan, R.  Glucocorticoid agonists as well as antagonists are effective inducers of mouse mammary tumor virus RNA in mouse mammary tumor cells treated with inhibitors of ADP-ribosylation. Journal of cellular physiology. 1986.  129, 36-42. [PubMed]
125. Ralhan, R. and Johnson, G. S.  Destabilization of cytoplasmic mouse mammary tumor RNA by heat shock: prevention by cycloheximide pretreatment. Biochemical and biophysical research communications. 1986.  137, 1028-1033. [PubMed]
126. Ralhan, R., Band, A. H., Roy, A., Hajini, G. H., Sharma, A. K. and Talwar, G. P.  An enzyme immunoassay titrating IgM antibody against phenolic glycolipid for diagnosis of lepromatous leprosy. The Indian journal of medical research. 1985.  82, 110-115. [PubMed]

 
Book Chapters:
Ranju Ralhan, Contributor to Genetic and Related effects, Section: Mutations: oncogenes and tumour suppressor genes, IARC Monographs Evaluation of Carcinogenic Risks to Humans, Smokless tobacco and some related nitrosamines, volume 89, 2004.
Ranju Ralhan, Contributor to Genetic and Related effects, Section: Mutations: oncogenes and tumour suppressor genes, IARC Monographs Evaluation of Carcinogenic Risks to Humans, Betel quid and areca-nut chewing and some related nitrosamines, volume 85, 2003.
Ranju Ralhan. Molecular alterations in betel and tobacco related oral cancer: diagnostic and prognostic implications. Indian Journal of Clinical Biochemistry, 2002, Vol. 18.
Ranju Ralhan. Tobacco related oral precancer and cancer in India. Tobacco Counters Health A.K. Varma ed. Macmillan India, 2002, 89-92.
Jatinder Kaur and Ranju Ralhan. Unraveling the molecular basis of tobacco associated oral tumorigenesis. Tobacco Counters Health A.K. Varma ed. Macmillan India, 2002, 249-252.
Shilpi Soni, Ajay Matta, S.V.S.Deo, Meera Mathur and Ranju Ralhan. Tobacco Triggers Angiogenesis. Tobacco Counters Health A.K. Varma ed. Macmillan India, 2002, 237-239.
Anupam Kumar, S.A.B.Raju and Vinod Kochupillai and Ranju Ralhan. Qutting tobacco through Sudarshan Kriya Yoga. Tobacco Counters Health A.K. Varma ed. Macmillan India, 2002, 221-223.
Nidhi Rohatgi, Anurag Srivastava and Ranju Ralhan. Guthka Chewing: An Emerging Epidemic. Tobacco Counters Health A.K. Varma ed. Macmillan India, 2002, 93-97.
B.S.A. Raju and Ranju Ralhan. Tobacco: Genetic susceptibility and Breast Cancer. Tobacco Counters Health A.K. Varma ed. Macmillan India, 2002, 245-248.
Nitin Chakravarti, Shilpi Soni and Ranju Ralhan. Ets-1 and P-glycoprotein: Putative regulators of proliferation and survival in betel and tobacco related human oral cancer. Oral Oncology, A.K. Varma ed. Vol. VII, 2001, 1-4.
Ranju Ralhan, Rinu Khanna, Shilpi Soni, Nitin Chakravarti, Jatinder Kaur, Meera Mathur and Nootan Kumar Shukla. Genechips: A Step Forward In Understanding Tobacco Associated Cancers. Tobacco Counters Health A.K Varma ed. MacMillan India Ltd. 2000, 129-133.
Jatinder Kaur, Nitin Chakravarti, Meera Mathur, Anurag Srivastava SVS Deo, Ranju Ralhan. Gutkha / Pan Masala Associated Oral Submucous Fibrosis: Molecular Alterations In Osf Pathogenesis. Tobacco Counters Health A.K Varma ed. MacMillan India Ltd. 2000, 144-151.
Rinu Khanna, Sonia Arora, Robin Mathew, Sonia Arora, Meera Mathur, T.K. Chattopadhyay, Nootan Kumar Shukla and Ranju Ralhan. Bidi Smoking Associated Esophageal Cancer In The Indian Subpopulation. Tobacco Counters Health A.K Varma ed. MacMillan India Ltd. 2000, 94- 98.
Nitin Chakravarti, Meera Mathur, Sudhir Bahadur, Nootan Kumar Shukla, Ranju Ralhan. Tobacco Abused Oral Precancerous Lesions: Plausible Targets For Chemoprevention. Tobacco Counters Health A.K Varma ed. MacMillan India Ltd. 2000, 139-143.
Neera Nath, Nitin Chakravarti, Meera Mathur, SVS Deo and Ranju Ralhan. Tobacco Use And Misuse: An Emerging Epidemic. Tobacco Counters Health A.K Varma ed. MacMillan India Ltd. 2000, 61-64.
Shilpi Soni, Prerna Pande, Meera Mathur, Nootan Kumar Shukla and Ranju Ralhan. Tobacco Chewing: Effect on Clinicopathological and Molecular Parameters Of Oral Cancer Patients. Tobacco Counters Health A.K Varma ed. MacMillan India Ltd. 2000, 134-138.
Tina Mukherjee, T.K. Chatopadhyay, Meera Mathur and Ranju Ralhan. Molecular Alterations in Tobacco Associated Esophageal Cancer. Tobacco Counters Health A.K Varma ed. MacMillan India Ltd. 2000 175-178.
Ranju Ralhan and Jatinder Kaur. Biological effects of hyperthermia and cancer. Proceedings of the symposium on Low level electromagnetic phenomena in biological systems. Feb. 1999, New Delhi, 90-93.
Ranju Ralhan, Sandhya Agarwal, Prerna Pande, Neera Nath, Jasbir Kaur and Jatinder Kaur. Molecular alterations in oral tumorigenesis: Diagnostic / prognostic implications. Oral Oncology, A.K. Varma ed. Vol.VI, 1999, 63-66.
Rajeeb K. Swain, Meera Mathur, N.K. Shukla and Ranju Ralhan. Clinical drug resistance in oral cancer is multifactorial. Oral Oncology, A.K.Varma ed. Vol.VI, 1999, 282-292.
Nitin Chakravarti, Meera Mathur, Sudhir Bahadur and Ranju Ralhan. Differential expression of nuclear retinoid receptors in human oral tumorigenesis. Oral oncology, A.K. Varma, Vol.VI, 1999, 105-108, Macmillan, India.
Jatinder Kaur and Ranju Ralhan. Liposomal drugs: A novel approach for circumvention of MDR in oral Cancer. Oral Oncology, A.K. Varma, Vol. VI, 1999, 151-154. Macmillan, India.
Molina M. Sewal, Rimple Bahl, Neera Nath, Meera Mathur, Nootan K. Shukla and Ranju Ralhan. Alterations in CDKN2 encoded gene product in human esophageal carcinoma. Oral Oncology, A.K. Varma, Vol.VI, 1999, 119-122. Macmillan, India.
Prerna Pande, Meera Mathur, Nootan K. Shukla and Ranju Ralhan. Alterations cell cycle regulatory proteins in human oral tumorigenesis. Oral Oncology, A.K. Varma, Vol.VI, 1999, 15-18. Macmillan, India.
Monalisa Rao, Jatinder Kaur, Meera Mathur, Anurag Srivastava and Ranju Ralhan. Molecular alterations in Oral Submucous Fibrosis. Oral Oncology, A.K. Varma, Vol. VI, 1999, 67-70. Macmillan, India.
Jasbir Kaur, Jatinder Kaur, Anurag Srivastava and Ranju Ralhan. Significance of HSP70 overexpression in pathogenesis oral cancer. Oral Oncology, A.K. Varma, Vol. VI, 1999, 109-113. Macmillan, India.
Sandhya Agarwal, Meera Mathur, Anurag Srivastava and Ranju Ralhan. Differential expression of MDM2in human oral tumorigenesis. Oral Oncology, A.K. Varma, Vol.VI, 1999, 101-104. Macmillan, India.
Sonia Arora, Meera Mathur, Tushar K. Chattopadhyay and Ranju Ralhan. Esophageal cancer: Correlation of molecular alterations with dietary factors. Oral Oncology A.K. Varma, Vol.VI, 1999, 11-14. Macmillan, India.
Neera Nath, Gulam Nabi, Anurag Srivastava and Ranju Ralhan. GST MI: A Susceptibility factor for oral leukoplakia in the Indian population. Oral Oncology, A.K. Varma, Vol. VI, 1999, 115-118. Macmillan, India.
Ranju Ralhan and Jasbir Kaur. Clinical Multidrug Resistance: A multifactorial problem. Invention Intelligence 1999, In Press.
Ranju Ralhan, Neera Nath, Sandhya Agarwal, Jasbir Kaur and N.K.Shukla. Serum p53 antibodies as early markers of oral cancer: Correlation with p53 alterations. The Immunologist 1998, Supplement 1, 102.
Ranju Ralhan and Jasbir Kaur. Viruses and Cancer. Invention Intelligence. 1997: 494-495.
Ranju Ralhan, Jasbir Kaur and Anurag Srivastava. Prognostic significance of coexpression of p53 and HSP70 in Human Oral Carcinomas. In A.K. Varma ed. Oral Oncology, Vol. IVB, pp 37-40, 1995. Macmillan India.
Ranju Ralhan, Jasbir Kaur, Murli Narayan. Overexpression of 70kDa stress protein in squamous cell carcinomas of human uterine cervix. Proceedings of the XVI International Cancer Congress Ed. R.S. Rao, M.G. Deo and L.D. Sanghvi. Monduzzi Editors. Italy Vol.3, pp. 2283-2286, 1994.
Jasbir Kaur, Gautam Sarkar, Anurag Srivastava and Ranju Ralhan. Immunological evidence for the association of p53 with a heat shock protein in squamous cell carcinoma of oral cavity. Proceedings of XVI International Congress. Vol.2, pp-919-921, 1994.
Murli Narayan, Jasbir Kaur, Poonam Salotra, Shyam S. Chauhan, N.K. Shukla and Ranju Ralhan. Multidrug resistance in oral SCC is mediated by the multidrug transporter. Proceedings of the XVI International cancer Congress Vol.2, pp. 975-978, 1994.
Tamiz P. Chelvi, S.K. Jain and Ranju Ralhan. Thermochemotherapy of murine melanomas using heat sensitive liposomes containing melphalan and hyperthermia. Proceedings of the XVI International Cancer Congress. Vol. 2, pp.829-833, 1994.
Ranju Ralhan and Jasbir Kaur. In vitro cytotoxicity assay for prediction of thermochemosensitivity of human oral squamous cell carcinoma. Oral Oncology Vol. IIIA pp.155-158, 1994.
Jasbir Kaur, Anurag Srivastava and Ranju Ralhan. p53 protein overexpression: An early biomarker for Oral Cancer. Oral Oncology. Vol. IIIA, pp.107-109, 1994.
Murli Narayan, Jasbir Kaur, Shyam S. Chauhan, N.K. Shukla and Ranju Ralhan. P-glycoprotein overexpression: A plausible mechanism for drug resistance in human oral cancer. Oral Oncology Vol. IIIA, pp. 142-144, 1994.
Jasbir Kaur and Ranju Ralhan. Curing the cervical cancer. Invention Intelligence 1993, 28: 197- 201.
Jasbir Kaur, Anurag Srivastava and Ranju Ralhan. Specific interacrtion between p53 protein and 70 kDa heat shock protein in human tumors. Cancer Research 1992, 33 Suppl. (Abs).
Jasbir Kaur and Ranju Ralhan. Oral Cancer: Curing the Incurable. Invention Intelligence 1992, 28: 176-179.
Ranju Ralhan and Alka Agarwal. An enzyme immunoassay for measurement of 70kD hsp. Cancer Research 1991, 32 Suppl. 391.
Shail K. Sharma, Madhav Bhatia and Ranju Ralhan. Mechanism of development of tolerance and dependence of opioids in Neuroblastoma Y Glioma hybrid cells and Mice. National Institute of Drug Abuse Research Monograph Series 1988, 87: 157-166.
Shail K. Sharma, Madhav Bhatia and Ranju Ralhan. Ascorbate abolishes the oiate induced compensatory increase in Adenylate cyclase by inhibition of lowkm GTPase. Proceedings of International Narcotics Research Symposium, 1988.
Shail K. Sharma, Madhav Bhatia and Ranju Ralhan. The role of endongenous opiod peptides in the development of Tolerance and dependence to opiods. National Institute on Drug Abuse Resarch. Monograph Series 1987.
 
Grant Support:
Project Title Role Funding Agency Sanction Number Sanction Date
Functional Analysis and clinical significance of Novel molecular targets in cytoskeletal reoganisation and locoregional spread of oral cancer using Proteomics Principal Investigator Department of Biotechnology, Government of India 2005-2008
Designing of Methylation target arrays for Breast Cancer Principal Investigator Department of Biotechnology, Government of India 2005-2006
Characterization and functional analysis of differentially expressed genes in esophageal cancer Principal Investigator Department of Science & Technology, Government of India 2005-2008
Relationship between polymorphisms in drug metabolizing enzymes, CYP1A1 and GSTM1 and the risk of developing oral precancer and cancer among consumers of tobacco and chewing products Principal Investigator Indian Council of Medical Research 2002-2007
Gene expression profile analysis of human esophageal cancer using cDNA microarrays Principal Investigator Indian Council of Medical Research 2002-2005
Role of genomic instability due to alterations of recombination factors p53 and BRCA1 in the pathogenesis of breast cancer Principal Investigator Indo German Project 2002-2005
Multicentric National Program on Evaluation and validation of molecular markers in oral cancer Co-Ordinator Department of Biotechnology, Government of India 2001-2004
Role of Retinoids and their receptors in the development and prevention of Oral Cancer Department of Biotechnology, Government of India 2001-2003
Molecular alterations in human esophageal cancer: potential prognostic implications Indian Council of Medical Research 2000-2003
Identification and characterization of differentially expressed genes in human esophageal cancer Department of Science & Technology, Government of India 2000-2003
Development of p53-ELISA diagnostic kit for early diagnosis of cancer Bridge Project Indo-French Industry-Institution Project Indo-French Centre 2001-2002
Study of Genetic alterations in Precancerous and Cancerous Oral Lesions Indo-French Centre for Promotion of Advanced Research, New Delhi 1996-1999
Genetic alterations in Human Esophageal Cancer Diagnostic/Prognostic implications Council of Scientific and Industrial Research, Government of India 1998-2000
Study of Multidrug Resistance in Human Oral Cancer Department of Science & Technology, Government of India 1995-1998
Study of Tumor Suppressor Gene p53 in Human Oral Cancer Council of Scientific and Industrial Research, Government of India 1994-1997
Signal transduction mechanism mediating hyperthermic killing of malignant cells Department of Science & Technology, Government of India 1990-1993
Isolation and identification of Heat Shock induced proteins of human neoplastic cells for potential use in immunodiagnosis of neoplasia All India Institute of Medical Sciences, New Delhi, India 1987-1989

 
 
My CV:   Download
 
Education 
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M.Sc. Postgraduate Institute of Medical Education and Research, Chandigarh, India, 1974-1976
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Ph.D. Vallabhbhai Patel Chest Institute, University of Delhi, India, 1976-1980
Honors and Awards
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Fellow of National Academy of Medical Sciences
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2002, Best Research Paper in American Society of Clinical Oncology-Pan Asia Cancer Conference
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2001, Dr. P.N. Raju Oration Award for Cancer of ICMR
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1996, Sandoz Award for Cancer Oration of ICMR
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Faculty Fellow of International Congress on Oral Cancer, Nominated and elected by Faculty Fellows of International Congress on Oral Cancer
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Best Poster of Day Award in 6th International Congress on Oral Cancer
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1976, First Prize in recognition of Merit - M.Sc. (Biochemistry) awarded by PGIMER
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1972, Merit Prize - B.Sc. (Hons.) Chemistry Part II awarded by University of Delhi
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1971, Merit Prize - B.Sc. (Hons.) Chemistry Part I awarded by University of Delhi
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1971-1978, National Science Talent Scholarship awarded by N.C.E.R.T for the period
Member
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American Association for Cancer Research
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New York Academy of Sciences
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Indian Association for Cancer Research
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Indian Society of Cell Biology
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Indian Immunology Society
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Association of Clinical Biochemists of India
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Biotechnology Society of India
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2005, Scientific Advisory Group Member for Preamble for Monographs on the Evaluation of Carcinogenic Risks to Humans, International Agency for Research in Cancer.
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Working Group Member for Monograph on the Evaluation of Carcinogenic Risks to Humans, Volume 89, 2004, Smokeless Tobacco and Some Related Nitrosamines, International Agency for Research in Cancer.
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Working Group Member for Monograph on the Evaluation of Carcinogenic Risks to Humans, Volume 85, 2004, Betel Quid, Areca-nut chewing and Some Related Nitrosamines, International Agency for Research in Cancer.
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Project Advisory Committee, National Cancer Control Programme, Ministry of Health and Family Welfare
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Statuary Warning for Health Hazards of Tobacco, Ministry of Health & Family Welfare
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Joint Secretary of Indian Association for Cancer Research
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Executive member of Indian Society of Cell Biology
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Project Advisory Committee & Expert Group of Indian Council of Medical Research
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Project Advisory Committee, Opthalmology, ICMR
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Project Advisory Committee and Expert Group of Indian Council of Medical Research.
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Expert Group (Cancer), Ministry of Health & Family Welfare
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Expert, Union Public Service Commission
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2001, Expert, Scientific Research Committee of the Gujarat Cancer Society
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Selection Committee for Research Associate, Institute of Pathology, ICMR
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DBT Nominee, Institutional Biosafety Committee of Dabur Research Foundation
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Expert, Advanced Centre for Treatment, Research & Education in Cancer, Mumbai.
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Expert, Chittranjan National Cancer Institute, Kolkatta
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Selection Committee for JRF/SRF Institute of Cytology and Pathology, ICMR
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Selection Committee for SRF, VP Chest Institute New Delhi
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Patent Cell Committee, AIIMS, New Delhi
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Selection Committee for Staff appointment in Research Projects, AIIMS
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Convocation Committee, AIIMS
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Institute Day Celebrations Committee, AIIMS
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Reviewer- Oncogene, International Journal of Cancer, Oral Diseases, World Journal of Surgical Oncology, Annals of Oncology, Neoplasia, Indian Journal of Experimental Biology, Indian Journal of Medical Research, Journal of Biosciences, Current Science, Indian Journal of Clinical Biochemistry
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Reviewer for Grant Proposals- Indo-French Center for Promotion of Advanced Research, Council of Scientific & Industrial Research, Indian Council of Medical Research, Department of Science & Technology, Department of Biotechnology, Department of Atomic Energy
Type of Neoplasms
 
Head and Neck
Oral cavity
Gastrointestinal tract
Esophagus
  Last modified on : Mar 4, 2011
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.