INCREDB ID : 160
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Pradeep Seth, M.D.
Professor 
 
Seth Research Foundation
H 8/3 First Floor, DLF City Phase-I
Gurgaon - 122 002   
Haryana   
 
E-mail: seth.res.fdn@gmail.com
Phone: +91-124-4380884, 4380885
 
URL: http://pradeepseth.com/
 
Positions Held:
Position Affiliation Time Period
President Seth Research Foundation, Gurgaon, India 2005-Present
Consultant Seth Research Foundation, Gurgaon, India 2005-Present
Consultant Dr Lal PathLabs Pvt Ltd, Gurgaon, India 2006-2009
Professor and Head All India Institue of Medical Sciences, New Delhi, India 1992-2005
Research Associate All India Institute of Medical Sciences, New Delhi, India
 
Area of Specialization:
Virology
Research Summary:
Construction of Indian subtype HIV-1 vaccine candidate
Demonstration of genetic heterogeneity of HIV-1 strains and dengue viruses circulating in different parts of India
Development of genotypic and phenotypic assays based on patented technology for determining the resistance of HIV-1 isolates to antiretroviral drugs
Demonstrated two subtypes of HSV-2 based on their oncogenic properties
Demonstrated causal relationship of HPV types 16, 18, 31 and 35 with cervical cancer in Indian women
Development of ELISA based test system for detection HIV-1 and 2 antibodies
Development of a cost effective and highly sensitive real time PCR based assay to qualitative and quantitative determination of HIV load and also HCV load
Development of HCV genotyping assay based on liquid hybridization technique
Development of PCR test to detect and typing dengue virus within first three days of infection
 
Publications:
1. Vajpayee, M., Singh, U. B., Seth, P. and Broor, S.  Comparative evaluation of various commercial assays for diagnosis of dengue fever. The Southeast Asian Journal of Tropical Medicine and Public Health. 2001.  32, 472-475. [PubMed]
2. Sahni, A. K., Prasad, V. V. and Seth, P.  Genomic diversity of human immunodeficiency virus type-1 in India. International Journal of STD & AIDS. 2002.  13, 115-118. [PubMed]
3. Hemal, A. K., Gupta, N. P., Rajeev, T. P., Kumar, R., Dar, L. and Seth, P.  Polymerase chain reaction in clinically suspected genitourinary tuberculosis: comparison with intravenous urography, bladder biopsy, and urine acid fast bacilli culture. Urology. 2000.  56, 570-574. [PubMed]
4. Lodha, R., Singhal, T., Jain, Y., Kabra, S. K., Seth, P. and Seth, V.  Pediatric HIV infection in a tertiary care center in North India: early impressions. Indian Pediatrics. 2000.  37, 982-986. [PubMed]
5. Vajpayee, M., Mohankumar, K., Wali, J. P., Dar, L., Seth, P. and Broor, S.  Dengue virus infection during post-epidemic period in Delhi, India. The Southeast Asian Journal of Tropical Medicine and Public Health. 1999.  30, 507-510. [PubMed]
6. Khatter, S., Singh, U. B., Arora, J., Rana, T. and Seth, P.  Mycobacterial infections in human immuno-deficiency virus seropositive patients: role of non-tuberculous mycobacteria. The Indian Journal of Tuberculosis. 2008.  55, 28-33. [PubMed]
7. Ray, S., Broor, S. L., Vaishnav, Y., Dar, L., Seth, P. and Broor, S.  Expression and humoral immune response to hepatitis C virus using a plasmid DNA construct. Indian Journal of Medical Microbiology. 2003.  21, 93-97. [PubMed]
8. Kumar, S., Aggarwal, P., Vajpayee, M., Pandey, R. M. and Seth, P.  Development of a candidate DNA/MVA HIV-1 subtype C vaccine for India. Vaccine. 2006.  24, 2585-2593. [PubMed]
9. Vajpayee, M., Kaushik, S., Sreenivas, V., Wig, N. and Seth, P.  CDC staging based on absolute CD4 count and CD4 percentage in an HIV-1-infected Indian population: treatment implications. Clinical and Experimental Immunology. 2005.  141, 485-490. [PubMed]
10. Vajpayee, M., Kanswal, S., Wig, N. and Seth, P.  Evaluation of CD4 counts and percentages in the HIV infected Indian population. The Southeast Asian Journal of Tropical Medicine and Public Health. 2004.  35, 144-146. [PubMed]
11. Renuka, K., Kapil, A., Kabra, S. K., Wig, N., Das, B. K., Prasad, V. V., Chaudhry, R. and Seth, P.  Reduced susceptibility to ciprofloxacin and gyra gene mutation in North Indian strains of Salmonella enterica serotype Typhi and serotype Paratyphi A. Microbial Drug Resistance. 2004.  10, 146-153. [PubMed]
12. Agarwal, A., Sankaran, S., Vajpayee, M., Sreenivas, V., Seth, P. and Dandekar, S.  Correlation of immune activation with HIV-1 RNA levels assayed by real-time RT-PCR in HIV-1 subtype C infected patients in Northern India. Journal of clinical virology : the official publication of the Pan American. 2007.  40, 301-306. [PubMed]
13. Khan, I. F., Vajpayee, M., Prasad, V. V. and Seth, P.  Genetic diversity of HIV type 1 subtype C env gene sequences from India. AIDS research and human retroviruses. 2007.  23, 934-940. [PubMed]
14. Singh, U. B., Bhanu, N. V., Suresh, V. N., Arora, J., Rana, T. and Seth, P.  Utility of polymerase chain reaction in diagnosis of tuberculosis from samples of bone marrow aspirate. The American journal of tropical medicine and hygiene. 2006.  75, 960-963. [PubMed]
15. Suresh, N., Singh, U. B., Arora, J., Pande, J. N., Seth, P. and Samantaray, J. C.  Rapid detection of rifampicin-resistant Mycobacterium tuberculosis by in-house, reverse line blot assay. Diagnostic microbiology and infectious disease. 2006.  56, 133-140. [PubMed]
16. Suresh, N., Singh, U. B., Arora, J., Pant, H., Seth, P., Sola, C., Rastogi, N., Samantaray, J. C. and Pande, J. N.  rpoB gene sequencing and spoligotyping of multidrug-resistant Mycobacterium tuberculosis isolates from India. Infection, genetics and evolution . 2006.  6, 474-483. [PubMed]
17. Gupta, E., Vajpayee, M., Xess, I. and Seth, P.  Oral candidiasis in HIV-infected patients and its relation to CD4 + counts: an adjunct clinical marker of HIV disease progression. Tropical doctor. 2006.  36, 127. [PubMed]
18. Kumar, S., Aggarwal, P., Vajpayee, M., Pandey, R. M. and Seth, P.  Development of a candidate DNA/MVA HIV-1 subtype C vaccine for India. Vaccine. 2006.  24, 2585-2593. [PubMed]
19. Kaushik, S., Vajpayee, M., Sreenivas, V. and Seth, P.  Correlation of T-lymphocyte subpopulations with immunological markers in HIV-1-infected Indian patients. Clinical immunology. 2006.  119, 330-338. [PubMed]
20. Gupta, R. M., Prasad, V. V., Rai, A. and Seth, P.  Analysis of HIV type 1 subtype C full-length gag gene sequences from India: novel observations and plausible implications. AIDS research and human retroviruses. 2005.  21, 1066-1072. [PubMed]
21. Aggarwal, P., Kumar, S., Vajpayee, M. and Seth, P.  Adjuvant action of murine IL-2/Ig plasmid after intramuscular immunization with Indian HIV-1 subtype C recombinant env.gp 120 construct. Viral immunology. 2005.  18, 649-656. [PubMed]
22. Bhanu, N. V., Singh, U. B., Chakraborty, M., Suresh, N., Arora, J., Rana, T., Takkar, D. and Seth, P.  Improved diagnostic value of PCR in the diagnosis of female genital tuberculosis leading to infertility. Journal of medical microbiology. 2005.  54, 927-931. [PubMed]
23. Aggarwal, P., Pandey, R. M. and Seth, P.  Augmentation of HIV-1 subtype C vaccine constructs induced immune response in mice by CpG motif 1826-ODN. Viral immunology. 2005.  18, 213-223. [PubMed]
24. Kumar, S. and Seth, P.  Immunogenicity of recombinant Modified Vaccinia Ankara Viruses (rMVA) expressing HIV-1 Indian subtype C gag-protease and env-gp120 genes in mice. Viral immunology. 2004.  17, 574-579. [PubMed]
25. Chugh, P. and Seth, P.  Induction of broad-based immune response against HIV-1 subtype C gag DNA vaccine in mice. Viral immunology. 2004.  17, 423-435. [PubMed]
26. Amatya, R., Vajpayee, M., Kaushik, S., Kanswal, S., Pandey, R. M. and Seth, P.  Lymphocyte immunophenotype reference ranges in healthy Indian adults: implications for management of HIV/AIDS in India. Clinical immunology. 2004.  112, 290-295. [PubMed]
27. Singh, U. B., Suresh, N., Bhanu, N. V., Arora, J., Pant, H., Sinha, S., Aggarwal, R. C., Singh, S., Pande, J. N., Sola, C., Rastogi, N. and Seth, P.  Predominant tuberculosis spoligotypes, Delhi, India. Emerging infectious diseases. 2004.  10, 1138-1142. [PubMed]
28. Bhanu, N. V., Banavalikar, J. N., Kapoor, S. K. and Seth, P.  Suspected small-scale interpersonal transmission of Mycobacterium tuberculosis in wards of an urban hospital in Delhi, India. The American journal of tropical medicine and hygiene. 2004.  70, 527-531. [PubMed]
29. Vajpayee, M., Kanswal, S., Seth, P., Wig, N. and Pandey, R. M.  Tuberculosis infection in HIV-infected Indian patients. AIDS patient care and STDs. 2004.  18, 209-213. [PubMed]
30. Bhanu, N. V., van, S., van, E. and Seth, P.  Two mycobacterium fortuitum strains isolated from pulmonary tuberculosis patients in Delhi harbour IS6110 homologue. Diagnostic microbiology and infectious disease. 2004.  48, 107-110. [PubMed]
31. Ray, S., Broor, S. L., Vaishnav, Y., Sarkar, C., Girish, R., Dar, L., Seth, P. and Broor, S.  Transforming growth factor beta in hepatitis C virus infection: in vivo and in vitro findings. Journal of gastroenterology and hepatology. 2003.  18, 393-403. [PubMed]
32. Singh, U. B. and Seth, P.  PCR diagnosis of tuberculosis--experience in India. Indian journal of pediatrics. 2002.  69 Suppl 1, S20-4. [PubMed]
 

 
 
Education 
::
M.D.
Honors and Awards
::
2009, Prof. B. Das Memorial Oration of IAMM
::
2006, Chief of the Army Staff Award for the best published paper
::
2004, Appreciation Award of Sri Lanka College of Microbiologists
::
2002, IAMM-Endowment Award of the Indian Association of Medical Microbiologists
::
1999, Glaxo Oration Award of the National Academy of Medical Sciences
::
1997, Lok Sewa Award of the Chamber of Indian Trade and Industry for contribution in Medical Sciences
::
1995, Dr. S.S. Aggarwal oration award of the Indian Association of Medical Microbiologists for contribution in the field of Microbiology
::
1991, Fogarty International Fellowship of the National Institutes of Health, U.S.A. in the special programme on AIDS from May 1st 1990 to June 30
::
1986, Dr. Shanti Swaroop Bhatnagar Award of the Council of Scientific and Industrial Research for original contribution in the field of Medical Sciences
::
1985, Dr. J.B. Srivastava Oration Award of the Indian Council of Medical Research for research in the field of virology
::
1984, Hari Om Ashram Prerit Dr. S. Rangachari Research Endowment Executive Committee Award of the Association of Surgeons of India on Immunological aspects of breast cancer
::
1980, Nominated member of the New York Academy of Sciences
::
1978, Raja Ravi Sher Singh of Kalsia Memorial Award of the Indian Council of Medical Research for Cancer Research on Herpes simplex virus and cancer cervix
Member
::
American Society for Microbiology, USA
::
Indian Association of Microbiologists
::
Indian Society of Virology
  Last modified on : Mar 4, 2011
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