INCREDB ID : 16
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Soumen Chakraborty, Ph.D.
Scientist C 
 
Institute of Life Sciences
Nalco Square
Bhubaneswar - 751 023   
Orissa   
 
E-mail: soumen@ils.res.in, soumen_ils@yahoo.co.in
Phone: +91-674-2302420, 2300137, 2301476, Extn. 207
Fax: +91-674-2300728
 
URL: http://ils.res.in/schakrabarty.htm
 
Positions Held:
Position Affiliation Time Period
Scientist C Institute of Life Sciences, Bhubaneswar, India 2007-Present
Scientist B Institute of Life Sciences, Bhubaneswar, India 2005-2007
Research Assistant Professor University of Illinois, Chicago, USA 2003-2005
Instructor University of Illinois, Chicago, USA 2002-2003
Research Associate The Loyola University Medical Center, Chicago, USA 2000-2001
 
Area of Specialization:
Molecular Biology
Research Summary:
Transcription factors related to leukemia
Regulation of gene activity, mechanisms of gene repression and gene activation
Post-translational modification of proteins involved in leukemia
 
Publications:
1.
Kuila, N., Dash, N., Sahoo, D. P., Pattnayak, N. C., Biswas, G. and Chakraborty, S.  Presence of a new BCR-ABL kinase domain mutation, C330G in an imatinib naive patient with chronic myeloid leukemia: very low prevalence of BCR-ABL kinase domain mutations in patients with chronic myeloid leukemia from eastern India. Leukemia & Lymphoma. 2009.  50, 663-666. [PubMed]
2. Kuila, N., Sahoo, D. P., Kumari, M., Biswas, S., Patnaik, R. S., Pattnayak, N. C., Biswas, G. and Chakraborty, S.  EVI1, BAALC and AME: prevalence of the secondary mutations in chronic and accelerated phases of chronic myeloid leukemia patients from eastern India. Leukemia Research. 2009.  33, 594-596. [PubMed]
3. Chakraborty, S., Chakrabarti, A., Mukhopadhyay, S., Mukhopadhyay, S., Basu, A. J. and Mondal, S.  Orbital rhinosporidiosis. Journal of the Indian Medical Association. 2005.  103, 383-384. [PubMed]
4. Chakraborty, S., Chakrabarti, A., Maity, P. and Ray, B.  Atypical presentation of a primary iris cyst. Journal of the Indian Medical Association. 2004.  102, 36-37. [PubMed]
5. Chi, Y., Senyuk, V., Chakraborty, S. and Nucifora, G.  EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity. The Journal of Biological Chemistry. 2003.  278, 49806-49811. [PubMed]
6. Buonamici, S., Chakraborty, S., Senyuk, V. and Nucifora, G.  The role of EVI1 in normal and leukemic cells. Blood Cells, Molecules & Diseases. 2003.  31, 206-212. [PubMed]
7. Senyuk, V., Sinha, K. K., Chakraborty, S., Buonamici, S. and Nucifora, G.  P/CAF and GCN5 acetylate the AML1/MDS1/EVI1 fusion oncoprotein. Biochemical and Biophysical Research Communications. 2003.  307, 980-986. [PubMed]
8. Chakraborty, S., Sinha, K. K., Senyuk, V. and Nucifora, G.  SUV39H1 interacts with AML1 and abrogates AML1 transactivity. AML1 is methylated in vivo. Oncogene. 2003.  22, 5229-5237. [PubMed]
9. Chakraborty, S., Buonamici, S., Senyuk, V., Nucifora, G.  Ecotropic Viral Integration 1 Site (EVI1) and Myelodysplastic Syndrome 1 (MDS1)-EVI1. Atlas of Genetics and Cytogenetics in Oncology and Haematology. 2003.
10. Senyuk, V., Chakraborty, S., Mikhail, F. M., Zhao, R., Chi, Y. and Nucifora, G.  The leukemia-associated transcription repressor AML1/MDS1/EVI1 requires CtBP to induce abnormal growth and differentiation of murine hematopoietic cells. Oncogene. 2002.  21, 3232-3240. [PubMed]
11. Chhotray, G. P., Pal, B. B., Khuntia, H. K., Chowdhury, N. R., Chakraborty, S., Yamasaki, S., Ramamurthy, T., Takeda, Y., Bhattacharya, S. K. and Nair, G. B.  Incidence and molecular analysis of Vibrio cholerae associated with cholera outbreak subsequent to the super cyclone in Orissa, India. Epidemiology and Infection. 2002.  128, 131-138. [PubMed]
12. Chakraborty, S., Senyuk, V. and Nucifora, G.  Genetic lesions and perturbation of chromatin architecture: a road to cell transformation. Journal of Cellular Biochemistry. 2001.  82, 310-325. [PubMed]
13. Mukhopadhyay, A. K., Chakraborty, S., Takeda, Y., Nair, G. B. and Berg, D. E.  Characterization of VPI pathogenicity island and CTXphi prophage in environmental strains of Vibrio cholerae. Journal of Bacteriology. 2001.  183, 4737-4746. [PubMed]
14. Chakraborty, S., Garg, P., Ramamurthy, R., Thungapathra, M., Gautam, J.K., Kumar, C., Maiti, S., Yamasaki, S., Shimada, T., Takeda, Y., Ghosh, A., Nair, G.B.  Comparison of antibiogram, virulence genes, ribotypes and DNA fingerprints of Vibrio cholerae of matching serogroups isolated from hospitalized diarrhoea cases and from the environment during 1997-1998 in Calcutta. Indian Journal of Medical Microbiology. 2001. 50, 879-888.
15. Chakraborty, S., Senyuk, V., Sitailo, S., Chi, Y., Nucifora G.  Interaction of EVI1 with c-AMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles. The Journal of Biological Chemistry. 2001. 276, 44936-44943.
16. Basu, A., Mukhopadhyay, A. K., Garg, P., Chakraborty, S., Ramamurthy, T., Yamasaki, S., Takeda, Y. and Nair, G. B.  Diversity in the arrangement of the CTX prophages in classical strains of Vibrio cholerae O1. FEMS Microbiology Letters. 2000.  182, 35-40. [PubMed]
17. Basu, A., Garg, P., Datta, S., Chakraborty, S., Bhattacharya, T., Khan, A., Ramamurthy, S., Bhattacharya, S. K., Yamasaki, S., Takeda, Y. and Nair, G. B.  Vibrio cholerae O139 in Calcutta, 1992-1998: incidence, antibiograms, and genotypes. Emerging Infectious Diseases. 2000.  6, 139-147. [PubMed]
18. Ramamurthy, T., Chakraborty, S., Nair, G. B. and Bhattacharya, S. K.  Health impairments arising from drinking water resources contaminated with Vibrio cholerae. Schriftenreihe Des Vereins Fur Wasser-, Boden- Und Lufthygiene. 2000.  105, 29-34. [PubMed]
19. Chakraborty, S., Mukhopadhyay, A. K., Bhadra, R. K., Ghosh, A. N., Mitra, R., Shimada, T., Yamasaki, S., Faruque, S. M., Takeda, Y., Colwell, R. R. and Nair, G. B.  Virulence genes in environmental strains of Vibrio cholerae. Applied and Environmental Microbiology. 2000.  66, 4022-4028. [PubMed]
20. Garg, P., Chakraborty, S., Basu, I., Datta, S., Rajendran, K., Bhattacharya, T., Yamasaki, S., Bhattacharya, S. K., Takeda, Y., Nair, G. B. and Ramamurthy, T.  Expanding multiple antibiotic resistance among clinical strains of Vibrio cholerae isolated from 1992-7 in Calcutta, India. Epidemiology and Infection. 2000.  124, 393-399. [PubMed]
21. Chowdhury, N. R., Chakraborty, S., Eampokalap, B., Chaicumpa, W., Chongsa-Nguan, M., Moolasart, P., Mitra, R., Ramamurthy, T., Bhattacharya, S. K., Nishibuchi, M., Takeda, Y. and Nair, G. B.  Clonal dissemination of Vibrio parahaemolyticus displaying similar DNA fingerprint but belonging to two different serovars (O3:K6 and O4:K68) in Thailand and India. Epidemiology and Infection. 2000.  125, 17-25. [PubMed]
22. Chowdhury, N. R., Chakraborty, S., Ramamurthy, T., Nishibuchi, M., Yamasaki, S., Takeda, Y. and Nair, G. B.  Molecular evidence of clonal Vibrio parahaemolyticus pandemic strains. Emerging Infectious Diseases. 2000.  6, 631-636. [PubMed]
23. Chakraborty, S., Khanam, J., Takeda, Y. and Nair, G. B.  Application of PCR for detection of toxigenic Vibrio cholerae O1 in water samples during an outbreak of cholera. Transactions of the Royal Society of Tropical Medicine and Hygiene. 1999.  93, 527-528. [PubMed]
24. Guhathakurta, B., Sasmal, D., Pal, S., Chakraborty, S., Nair, G. B. and Datta, A.  Comparative analysis of cytotoxin, hemolysin, hemagglutinin and exocellular enzymes among clinical and environmental isolates of vibrio cholerae O139 and non-O1, non-O139. FEMS Microbiology Letters. 1999.  179, 401-407. [PubMed]
25. Bhattacharya, M. K., Dutta, D., Deb, A., Garg, P., Chakraborty, S., Mukhopadhyay, A. K., Bhattacharya, S. K. and Moitra, A.  Acute secretory traveller's diarrhoea caused by Vibrio cholerae which does not belong to the O1 or O139 serogroup. The National Medical Journal of India. 1998.  11, 248-249. [PubMed]
26. Hoshino, K., Yamasaki, S., Mukhopadhyay, A. K., Chakraborty, S., Basu, A., Bhattacharya, S. K., Nair, G. B., Shimada, T. and Takeda, Y.  Development and evaluation of a multiplex PCR assay for rapid detection of toxigenic Vibrio cholerae O1 and O139. FEMS Immunology and Medical Microbiology. 1998.  20, 201-207. [PubMed]
27. Chakraborty, S., Nair, G. B. and Shinoda, S.  Pathogenic vibrios in the natural aquatic environment. Reviews On Environmental Health. 1997.  12, 63-80. [PubMed]

 
Grant Support:
Project Title Role Funding Agency Sanction Number Sanction Date
Consequences of Post-translational Modification on the Proto-oncogene EVI1 Department of Science & Technology, Government of India 2006-2009
Molecular Monitoring of Secondary Mutations Potentially Involved in Disease Transformation of CML to CML-Blast Crisis Department of Biotechnology, Government of India 2006-2009

 
 
 
Education 
::
M.Sc. in Marine Microbiology, , National Institute of Cholera and Enteric Diseases, Calcutta, India, 1992-1993
::
Ph.D. in Microbiology, National Institute of Cholera and Enteric Diseases, Calcutta, India, 1996-1999
Honors and Awards
::
1998-1999, Fellowship was awarded by the Department of Molecular Microbiology, Washington University
::
1998-1999, Senior Research Fellowship from the Indian Council of Medical Research, Government of India
::
1996-1998, Junior Research Fellowship from the Department of Biotechnology, Government of India
::
1994-1995, Junior Research Fellowship from the Ministry of Environment and Forest, Government of India
::
2011, ICMR international fellow for Stem Cell Institute, K.U. Leuven, Leuven, Belgium
Member
::
Indian Association of Cancer Research
  Last modified on : Mar 4, 2011
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.