Anil Suri, Ph.D.
Scientist
National Institute of Immunology
Aruna Asaf Ali Marg
New Delhi - 110 067
E-mail: anil@nii.res.in
Phone: +91-11-26703700
URL: http://www.nii.res.in/faculty-06/AnilSuri.htm
Positions Held:
Position
Affiliation
Time Period
Scientist
National Institute of Immunology, New Delhi, India
Present
Visiting Faculty
Memorial Sloan-Kettering Cancer Center, New York, USA
Visiting Faculty
Center for Cancer Research, National Cancer Institute, NIH, Bethesda, USA
Visiting Faculty
Queens University Belfast, Belfast, UK
Visiting Faculty
Hyogo College of Medicine, Japan
Visiting Faculty
University of Virginia Health System, USA
Visiting Faculty
Cornell Medical College, New York, USA
Area of Specialization:
Molecular Biology
Research Summary:
Cancer immunotherapy
Biomarker discovery for cancer
Chemo-resistant discovery for cancer treatment
Monoclonal antibody tumor imaging
Tumor histopathology
Publications:
1.
Garg, M., Kanojia, D., Saini, S., Suri, S., Gupta, A., Surolia, A. and Suri, A. Germ cell-specific heat shock protein 70-2 is expressed in cervical carcinoma and is involved in the growth, migration, and invasion of cervical cells. Cancer. 2010. 116, 3785-3796. [PubMed]
2.
Kanojia, D., Garg, M., Saini, S., Agarwal, S., Kumar, R. and Suri, A. Sperm associated antigen 9 expression and humoral response in chronic myeloid leukemia. Leukemia Research. 2010. 34, 858-863. [PubMed]
3.
Garg, M., Kanojia, D., Seth, A., Kumar, R., Gupta, A., Surolia, A. and Suri, A. Heat-shock protein 70-2 (HSP70-2) expression in bladder urothelial carcinoma is associated with tumour progression and promotes migration and invasion. European Journal of Cancer. 2010. 46, 207-215. [PubMed]
4.
Garg, M., Kanojia, D., Suri, S., Gupta, S., Gupta, A. and Suri, A. Sperm-associated antigen 9: a novel diagnostic marker for thyroid cancer. The Journal of Clinical Endocrinology and Metabolism. 2009. 94, 4613-4618. [PubMed]
5.
Garg, M., Kanojia, D., Suri, S. and Suri, A. Small interfering RNA-mediated down-regulation of SPAG9 inhibits cervical tumor growth. Cancer. 2009. 115, 5688-5699. [PubMed]
6.
Garg, M., Kanojia, D., Salhan, S., Suri, S., Gupta, A., Lohiya, N. K. and Suri, A. Sperm-associated antigen 9 is a biomarker for early cervical carcinoma. Cancer. 2009. 115, 2671-2683. [PubMed]
7.
Kanojia, D., Garg, M., Gupta, S., Gupta, A. and Suri, A. Sperm-associated antigen 9, a novel biomarker for early detection of breast cancer. Cancer Epidemiology, Biomarkers & Prevention. 2009. 18, 630-639. [PubMed]
8.
Garg, M., Kanojia, D., Khosla, A., Dudha, N., Sati, S., Chaurasiya, D., Jagadish, N., Seth, A., Kumar, R., Gupta, S., Gupta, A., Lohiya, N. K. and Suri, A . Sperm-associated antigen 9 is associated with tumor growth, migration, and invasion in renal cell carcinoma. Cancer Research. 2008. 68, 8240-8248. [PubMed]
9.
Suri A. Report on the first international symposium on cancer biology (ISCB), November 14-16, 2007, at the National Institute of Immunology, New Delhi, India. Cancer Immunology, Immunotherapy : CII. 2009. 58, 311-316. [PubMed]
10.
Mathur, D., Anand, K., Mathur, D., Jagadish, N., Suri, A. and Garg, L. C. Crystallization and preliminary X-ray characterization of phosphoglucose isomerase from Mycobacterium tuberculosis H37Rv. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 2007. 63, 353-355. [PubMed]
11.
Garg, M., Chaurasiya, D., Rana, R., Jagadish, N., Kanojia, D., Dudha, N., Kamran, N., Salhan, S., Bhatnagar, A., Suri , S., Gupta, A. and Suri, A. Sperm-associated antigen 9, a novel cancer testis antigen, is a potential target for immunotherapy in epithelial ovarian cancer. Clinical Cancer Research. 2007. 13, 1421-1428. [PubMed]
12.
Rana, R., Jagadish, N., Garg, M., Mishra, D., Dahiya, N., Chaurasiya, D. and Suri, A. Immunogenicity study of recombinant human sperm-associated antigen 9 in bonnet macaque (Macaca radiata). Human Reproduction. 2006. 21, 2894-2900. [PubMed]
13.
Suri A. Cancer testis antigens--their importance in immunotherapy and in the early detection of cancer. Expert Opinion On Biological Therapy. 2006. 6, 379-389. [PubMed]
14.
Rana, R., Jagadish, N., Garg, M., Mishra, D., Dahiya, N., Chaurasiya, D. and Suri, A. Small interference RNA-mediated knockdown of sperm associated antigen 9 having structural homology with c-Jun N-terminal kinase-interacting protein. Biochemical and Biophysical Research Communications. 2006. 340, 158-164. [PubMed]
15.
Suri A. Sperm-based contraceptive vaccines: current status, merits and development. Expert Reviews in Molecular Medicine. 2005. 7, 1-16. [PubMed]
16.
Jagadish, N., Rana, R., Mishra, D., Garg, M., Chaurasiya, D., Hasegawa, A., Koyama, K. and Suri, A. Immunogenicity and contraceptive potential of recombinant human sperm associated antigen (SPAG9). Journal of Reproductive Immunology. 2005. 67, 69-76. [PubMed]
17.
Jagadish, N., Rana, R., Mishra, D., Kumar, M. and Suri, A. Sperm associated antigen 9 (SPAG9): a new member of c-Jun NH2 -terminal kinase (JNK) interacting protein exclusively expressed in testis. The Keio Journal of Medicine. 2005. 54, 66-71. [PubMed]
18.
Jagadish, N., Rana, R., Mishra, D., Garg, M., Selvi, R. and Suri, A. Characterization of immune response in mice to plasmid DNA encoding human sperm associated antigen 9 (SPAG9). Vaccine. 2006. 24, 3695-3703. [PubMed]
19.
Suri A. Contraceptive vaccines targeting sperm. Expert Opinion On Biological Therapy. 2005. 5, 381-392. [PubMed]
20.
Jagadish, N., Rana, R., Selvi, R., Mishra, D., Garg, M., Yadav, S., Herr, J. C., Okumura, K., Hasegawa, A., Koyama, K. and Suri, A. Characterization of a novel human sperm-associated antigen 9 (SPAG9) having structural homology with c-Jun N-terminal kinase-interacting protein. The Biochemical Journal. 2005. 389, 73-82. [PubMed]
21.
Verma, S., Mohapatra, B., Jagadish, N., Selvi, R., Roy, P., Rana, R., Lakshmi, K. and Suri, A. Molecular cloning, expression of testicular transcript abundant in germ cells and immunobiological effects of the recombinant protein. American Journal of Reproductive Immunology. 2004. 52, 164-173. [PubMed]
22.
Suri A. Sperm specific proteins-potential candidate molecules for fertility control. Reproductive Biology and Endocrinology : RB&E. 2004. 2, 10. [PubMed]
Grant Support:
Project Title
Role
Funding Agency
Sanction Number
Sanction Date
Cancer Research Program
Department of Biotechnology, Government of India
Cancer testis antigens-their importance in immunotherapy and in early detection of cancer
Department of Biotechnology, Government of India
Characterization of testis specific sperm associated antigen 9 (SPAG9) gene expression and humoral immune response in various human cancers
Department of Biotechnology, Government of India
Small interfering RNA-mediated inhibition of sperm associated antigen 9 (SPAG9) expression in human cancer cell lines in in vitro and in vivo
Department of Biotechnology, Government of India
Studies on sperm specific genes related with infertility
INDO-POLISH Grant
Contraceptive potential of Oocyte-restricted ePLA2g
INDO–US Grant
Education
::
Ph.D.
Honors and Awards
::
2009, Fellow, National Academy of Sciences, India
Member
::
Editorial Reviewer - Neoplasia, Vaccine, European Journal of Immunology, Biology of Reproduction,Molecular Reproduction and Development, Human Reproduction, Molecular Biology Reports, Current Science, Asian Journal of Andrology
::
Convener, Cancer Research Program
::
Chairperson, Institutional Bio Safety Committee