INCREDB ID : 151
Home >> Investigator Page Previous      Next
Geetanjali Sachdeva, Ph.D.
Scientist D 
 
National Institute for Research in Reproductive Health
Jehangir Merwanji Street, Parel
Mumbai - 400 012   
Maharashtra   
 
E-mail: sachdevag@nirrh.res.in
Phone: +91-22-24192007
 
URL: http://www.nirrh.res.in/staff/scientific/DrSachdeva_resume.htm
 
Positions Held:
Position Affiliation Time Period
Scientist National Institute for Research in Reproductive Health, Mumbai, India 1997-Present
Research Associate National Institute of Immunology, New Delhi, India 1996-1997
 
Area of Specialization:
Molecular Biology
Research Summary:
Mechanisms and molecular determinants of endometrial receptivity and implantation in primates
Hormone dependent variations in the endometrial tissue and uterine fluid proteomes
Hormonal regulation of telomerase in prostate cancer
 
Publications:
1. Chehna-Patel, N., Warty, N., Sachdeva, G. and Khole, V.  Proteolytic tailoring of the heat shock protein 70 and its implications in the pathogenesis of endometriosis. Fertility and Sterility. 2011.  [PubMed]
2. Chehna-Patel, N., Sachdeva, G., Gajbhiye, R., Warty, N. and Khole, V.  "Spot"-ting differences between the ectopic and eutopic endometrium of endometriosis patients. Fertility and Sterility. 2010.  94, 1964-2035. [PubMed]
3. Nimbkar-Joshi, S., Rosario, G., Katkam, R. R., Manjramkar, D. D., Metkari, S. M., Puri, C. P. and Sachdeva, G.  Embryo-induced alterations in the molecular phenotype of primate endometrium. Journal of Reproductive Immunology. 2009.  83, 65-71. [PubMed]
4. Rosario, G. X., Katkam, R. R., Nimbkar-Joshi, S., Modi, D. N., Manjramkar, D. D., Hinduja, I., Zaveri, K., Puri, C. P. and Sachdeva, G.  Expression of endometrial protein kinase a during early pregnancy in bonnet monkeys (Macaca radiata). Biology of Reproduction. 2009.  81, 1172-1181. [PubMed]
5. Parmar, T., Nimbkar-Joshi, S., Katkam, R. R., Gadkar-Sable, S., Chaudhari, U., Manjramkar, D. D., Savardekar, L., Jacob, S., Puri, C. P. and Sachdeva, G.  Differential expression of calreticulin, a reticuloplasmin in primate endometrium. Human Reproduction. 2009.  24, 2205-2216. [PubMed]
6. Parmar, T., Gadkar-Sable, S., Savardekar, L., Katkam, R., Dharma, S., Meherji, P., Puri, C. P. and Sachdeva, G.  Protein profiling of human endometrial tissues in the midsecretory and proliferative phases of the menstrual cycle. Fertility and Sterility. 2009.  92, 1091-1103. [PubMed]
7. Rosario, G. X., D'Souza, S. J., Manjramkar, D. D., Parmar, V., Puri, C. P. and Sachdeva, G.  Endometrial modifications during early pregnancy in bonnet monkeys (Macaca radiata). Reproduction, Fertility, and Development. 2008.  20, 281-294. [PubMed]
8. Parmar, T., Sachdeva, G., Savardekar, L., Katkam, R. R., Nimbkar-Joshi, S., Gadkar-Sable, S., Salvi, V., Manjramkar, D. D., Meherji, P. and Puri, C. P.  Protein repertoire of human uterine fluid during the mid-secretory phase of the menstrual cycle. Human Reproduction. 2008.  23, 379-386. [PubMed]
9. Sachdeva, G., D'Costa, J., Cho, J. E., Kachapati, K., Choudhry, V. and Arya, S. K.  Chimeric HIV-1 and HIV-2 lentiviral vectors with added safety insurance. Journal of Medical Virology. 2007.  79, 118-126. [PubMed]
10. Shah, C., Modi, D., Sachdeva, G., Gadkar, S., D'Souza, S. and Puri, C.  N-terminal region of progesterone receptor B isoform in human spermatozoa. International Journal of Andrology. 2005.  28, 360-371. [PubMed]
11. Modi, D., Shah, C., Sachdeva, G., Gadkar, S., Bhartiya, D. and Puri, C.  Ontogeny and cellular localization of SRY transcripts in the human testes and its detection in spermatozoa. Reproduction. 2005.  130, 603-613. [PubMed]
12. Patil, V. S., Sachdeva, G., Modi, D. N., Katkam, R. R., Manjramkar, D. D., Hinduja, I. and Puri, C. P.  Rab coupling protein (RCP): a novel target of progesterone action in primate endometrium. Journal of Molecular Endocrinology. 2005.  35, 357-372. [PubMed]
13. Rosario, G. X., Sachdeva, G., Manjramkar, D. D. and Puri, C. P.  Enhanced expressions of endometrial tumour necrosis factor alpha and its receptors during early pregnancy in bonnet monkeys. Cytokine. 2005.  31, 459-464. [PubMed]
14. Rosario, G. X., Sachdeva, G., Manjramkar, D. D., Modi, D. N., Meherji, P. K. and Puri, C. P.  Endometrial expression of immunomodulatory cytokines and their regulators during early pregnancy in bonnet monkeys (Macaca radiata). Human Reproduction. 2005.  20, 3039-3046. [PubMed]
15. Gadkar-Sable, S., Shah, C., Rosario, G., Sachdeva, G. and Puri, C.  Progesterone receptors: various forms and functions in reproductive tissues. Frontiers in Bioscience. 2005.  10, 2118-2130. [PubMed]
16. Sachdeva, G., Gadkar, S., Shah, C. A., Kholkute, S. D. and Puri, C. P.  Characterization of a critical region in the hormone binding domain of sperm progesterone receptor. International Journal of Andrology. 2005.  28, 120-124. [PubMed]
17. Rosario, G. X., Modi, D. N., Sachdeva, G., Manjramkar, D. D. and Puri, C. P.  Morphological events in the primate endometrium in the presence of a preimplantation embryo, detected by the serum preimplantation factor bioassay. Human Reproduction. 2005.  20, 61-71. [PubMed]
18. Shah, C., Modi, D., Sachdeva, G., Gadkar, S. and Puri, C.  Coexistence of intracellular and membrane-bound progesterone receptors in human testis. The Journal of Clinical Endocrinology and Metabolism. 2005.  90, 474-483. [PubMed]
19. Shah, C., Modi, D., Gadkar, S., Sachdeva, G. and Puri, C.  Progesterone receptors on human spermatozoa. Indian Journal of Experimental Biology. 2003.  41, 773-780. [PubMed]
20. Rosario, G., Sachdeva, G., Okulicz, W. C., Ace, C. I., Katkam, R. R. and Puri, C. P.  Role of progesterone in structural and biochemical remodeling of endometrium. Frontiers in Bioscience. 2003.  8, s924-35. [PubMed]
21. Gopalkrishnan, K., Katkam, R. R., Sachdeva, G., Kholkute, S. D., Padwal, V. and Puri, C. P.  Effects of an antiprogestin onapristone on the endometrium of bonnet monkeys: morphometric and ultrastructural studies. Biology of Reproduction. 2003.  68, 1959-1967. [PubMed]
22. Gadkar, S., Shah, C. A., Sachdeva, G., Samant, U. and Puri, C. P.  Progesterone receptor as an indicator of sperm function. Biology of Reproduction. 2002.  67, 1327-1336. [PubMed]
23. Sachdeva, G., Patil, V., Katkam, R. R., Manjramkar, D. D., Kholkute, S. D. and Puri, C. P.  Expression profiles of endometrial leukemia inhibitory factor, transforming growth factor beta2 (TGFbeta2), and TGFbeta2 receptor in infertile bonnet monkeys. Biology of Reproduction. 2001.  65, 1-8. [PubMed]
24. Puri, C. P., Katkam, R. R., Sachdeva, G., Patil, V., Manjramkar, D. D. and Kholkute, S. D.  Endometrial contraception: modulation of molecular determinants of uterine receptivity. Steroids. 2000.  65, 783-794. [PubMed]
25. Sachdeva, G., Shah, C. A., Kholkute, S. D. and Puri, C. P.  Detection of progesterone receptor transcript in human spermatozoa. Biology of Reproduction. 2000.  62, 1610-1614. [PubMed]

 
Grant Support:
Project Title Role Funding Agency Sanction Number Sanction Date
Hormonal regulation of human telomerase and its possible implications in the pathogenesis of prostate cancer Department of Atomic Energy, Board of Nuclear and Radiation Sciences, Government of India
Structural and molecular signatures of early pregnancy on primate endometrium Department of Science & Technology, Government of India
An inventory of secreted proteins and its modified forms in human uterine fluid Department of Biotechnology, Government of India
Expression and trafficking of cell surface adhesion molecules and their contribution to endometrial receptivity Department of Biotechnology, Government of India

 
 
 
Education 
::
M.Sc. in Life Sciences, Jawaharlal Nehru University, New Delhi, India
::
Ph.D. in Life Sciences, Jawaharlal Nehru University, New Delhi, India
Honors and Awards
::
2010, GP Talwar Mid Level Career Award by the Indian Society for the Study in Reproduction and Society
::
2009, 10th Royan International Research Award
::
2002-2003, Long term Biotechnology Overseas Associateship by Department of Biotechnology, Government of India to train at National Cancer Institute, National Institutes of Health, USA
::
2002, Young Scientist Fellowship to attend the Silver Jubilee Celebrations of the Centre for Cellular and Molecular Biology
::
Government of India to train at National Cancer Institute, National Institutes of Health, USA
::
Merit Prize for the paper presentation in the Xth International Congress on Immunology
::
1996, Young Scientist Award from the Indian Society of Human Genetics
Member
::
Indian Society for the Study in Reproduction and Fertility
::
Proteomics Society of India
  Last modified on : Mar 4, 2011
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.