Sandip K. Mishra, Ph.D.
Scientist D
Institute of Life Sciences
Nalco Square
Bhubaneswar - 751 023
Orissa
E-mail: sandipkmishra@ils.res.in, sandipkmishra@hotmail.com
Phone: +91-674-2300702, +91-674-2300137, 2301476, Extn: 234
Fax: +91-674-2300728
URL: http://ils.res.in/skmishra.htm
Positions Held:
Position
Affiliation
Time Period
Scientist D
Institute of Life Sciences, Bhubaneswar, India
2007-Present
Instructor
Department of Neurosurgery,University of Texas, MD Anderson Cancer Center, Houston, USA
2004-2007
Reader
Institute of Life Sciences, Bhubaneswar, India
2004
Post Doctoral Fellow
Dept. Molecular and Cellular Oncology, University of Texas, MD Anderson Cancer Center, Houston, USA
2000-2004
Project Associate
National Institute of Immunology, New Delhi, India
1998-1999
Area of Specialization:
Molecular Oncology
Research Summary:
Chromatin remodeling in breast cancer
Publications:
1.
Mishra, S. K. , Mandal, M., Mazumdar, A. and Kumar, R. Dynamic chromatin remodeling on the HER2 promoter in human breast cancer cells. FEBS Letters. 2001. 507, 88-94. [PubMed]
2.
Mazumdar, A., Wang, R. A., Mishra, S. K. , Adam, L., Bagheri-Yarmand, R., Mandal, M., Vadlamudi, R. K. and Kumar, R. Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor. Nature Cell Biology. 2001. 3, 30-37. [PubMed]
3.
Talukder, A. H., Jorgensen, H. F., Mandal, M., Mishra, S. K. , Vadlamudi, R. K., Clark, B. F., Mendelsohn, J. and Kumar, R. Regulation of elongation factor-1alpha expression by growth factors and anti-receptor blocking antibodies. The Journal of Biological Chemistry. 2001. 276, 5636-5642. [PubMed]
4.
Prithivirajsingh, S., Mishra, S. K. and Mahadevan, A. Functional analysis of a chromosomal arsenic resistance operon in Pseudomonas fluorescens strain MSP3. Molecular Biology Reports. 2001. 28, 63-72. [PubMed]
5.
Prithivirajsingh, S., Mishra, S. K. and Mahadevan, A. Detection and analysis of chromosomal arsenic resistance in Pseudomonas fluorescens strain MSP3. Biochemical and Biophysical Research Communications. 2001. 280, 1393-1401. [PubMed]
6.
Li, F., Mandal, M., Mishra, S. K. , Barnes, C. J. and Kumar, R. Heregulin promotes expression and subcellular redistribution of ADP-ribosylation factor 3. FEBS Letters. 2002. 524, 49-53. [PubMed]
7.
Talukder, A. H., Mishra, S. K. , Mandal, M., Balasenthil, S., Mehta, S., Sahin, A. A., Barnes, C. J. and Kumar, R. MTA1 interacts with MAT1, a cyclin-dependent kinase-activating kinase complex ring finger factor, and regulates estrogen receptor transactivation functions. The Journal of Biological Chemistry. 2003. 278, 11676-11685. [PubMed]
8.
Mishra, S. K. , Mazumdar, A., Vadlamudi, R. K., Li, F., Wang, R. A., Yu, W., Jordan, V. C., Santen, R. J. and Kumar, R. MICoA, a novel metastasis-associated protein 1 (MTA1) interacting protein coactivator, regulates estrogen receptor-alpha transactivation functions. The Journal of Biological Chemistry. 2003. 278, 19209-19219. [PubMed]
9.
Cheema, S. K., Mishra, S. K. , Rangnekar, V. M., Tari, A. M., Kumar, R. and Lopez-Berestein, G. Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter. The Journal of Biological Chemistry. 2003. 278, 19995-20005. [PubMed]
10.
Barnes, C. J., Vadlamudi, R. K., Mishra, S. K. , Jacobson, R. H., Li, F. and Kumar, R. Functional inactivation of a transcriptional corepressor by a signaling kinase. Nature Structural Biology. 2003. 10, 622-628. [PubMed]
11.
Mishra, S. K. , Yang, Z., Mazumdar, A., Talukder, A. H., Larose, L. and Kumar, R. Metastatic tumor antigen 1 short form (MTA1s) associates with casein kinase I-gamma2, an estrogen-responsive kinase. Oncogene. 2004. 23, 4422-4429. [PubMed]
12.
Mishra, S. K. , Balasenthil, S., Nguyen, D. and Vadlamudi, R. K. Cloning and functional characterization of PELP1/MNAR promoter. Gene. 2004. 330, 115-122. [PubMed]
13.
Mishra, S. K. , Talukder, A. H., Gururaj, A. E., Yang, Z., Singh, R. R., Mahoney, M. G., Franci, C., Vadlamudi, R. K. and Kumar, R. Upstream determinants of estrogen receptor-alpha regulation of metastatic tumor antigen 3 pathway. The Journal of Biological Chemistry. 2004. 279, 32709-32715. [PubMed]
14.
Talukder, A. H., Gururaj, A., Mishra, S. K. , Vadlamudi, R. K. and Kumar, R. Metastasis-associated protein 1 interacts with NRIF3, an estrogen-inducible nuclear receptor coregulator. Molecular and Cellular Biology. 2004. 24, 6581-6591. [PubMed]
15.
Nair, S. S., Mishra, S. K. , Yang, Z., Balasenthil, S., Kumar, R. and Vadlamudi, R. K. Potential role of a novel transcriptional coactivator PELP1 in histone H1 displacement in cancer cells. Cancer Research. 2004. 64, 6416-6423. [PubMed]
16.
Amano, T., Nakamizo, A., Mishra, S. K. , Gumin, J., Shinojima, N., Sawaya, R. and Lang, F. F. Simultaneous phosphorylation of p53 at serine 15 and 20 induces apoptosis in human glioma cells by increasing expression of pro-apoptotic genes. Journal of Neuro-oncology. 2009. 92, 357-371. [PubMed]
17.
Sar, P., Peter, R., Rath, B., Das, M. and Mishra, S. K. 3, 3'5 Triiodo L thyronine induces apoptosis in human breast cancer MCF-7 cells, repressing SMP30 expression through negative thyroid response elements. PloS One. 2011. 6, e20861. [PubMed]
18.
Sar, P., Bhargava, D. K., Sengupta, D., Rath, B., Chaudhary, S., and Mishra, S. K. In Human Breast Cancer Cells TRβ Competes with ERα for Altering Bcl2/Bax ratio through SMP30-Mediated P53 Induction. Journal of Cancer Science & Therapy . 2012. In press.
19.
Chaudhary, S., Panda, A. K.,Mishra, D. K. and Mishra, S. K. Association of +331G/A PgR polymorphism with susceptibility to female reproductive cancer: Evidence from a meta-analysis. PloS One. 2013. In press.
20.
Mishra, S. K. , Sengupta, D., Sar, P. and Bhargava, D. Molecular Basis of Aging and Breast Cancer. J ournal of Cancer Science & Therapy. 2013. In press. Invited review.
21.
Mishra, S. K. , Kumari, K. and Bhargava, D. A Review on EZH2 and its Epigenetic Association with Breast Cancer. Journal of Cancer Research Updates. 2013. In press. Invited review.
Education
::
Ph.D.
Honors and Awards
::
2003, Amgen award in Basic Science Research at UT MD Anderson Cancer Center, Houston, Texas.
Member
::
Associate Editor - World Journal of Cancer Research (American Scientific Publishers)
::
Editor - Journal of Cancer Science and Therapy