Pankaj M. Shah, M.D.
Advisor
Gujarat Cancer & Research Institute
Department of Medical Oncology
The Gujarat Cancer Society, Civil Hospital Campus, Asarwa
Ahmedabad - 380 016
Gujarat
Phone: +91-79-26444344
Fax: +91-79-22685490
URL: http://cancerindia.org/director.html
Area of Specialization:
Oncology
Publications:
1.
Vaswani, B. A., Shah, M., Shah, P. M. , Parikh, B. J., Anand, A. S. and Sharma, G. L. Giant mesenteric fibromatosis in Gardner's syndrome. Indian Journal of Cancer. 2011. 48, 140-142. [PubMed]
2.
Vora, H. H., Shukla, S. N., Brahambhatt, B. V., Mehta, S. H., Patel, N. A., Parikh, S. K., Shah, K. N. and Shah, P. M. Clinical relevance of FLT3 receptor protein expression in Indian patients with acute leukemia. Asia-Pacific Journal of Clinical Oncology. 2010. 6, 306-319. [PubMed]
3.
Patel, B. P., Trivedi, P. J., Brahmbhatt, M. M., Shukla, S. N., Shah, P. M. and Bakshi, S. R. Mutagen sensitivity in oral cancer patients, healthy tobacco chewers and controls. Acta Cytologica. 2010. 54, 169-174. [PubMed]
4.
Vora, H. H., Mehta, S. V., Shukla, S. N. and Shah, P. M. No mutation detected in five hot spot codons of the TP53 gene by restriction site mutation analysis in patients with carcinoma of the tongue. The International Journal of Biological Markers. 2010. 25, 46-51. [PubMed]
5.
Patel, J. B., Shah, F. D., Shukla, S. N., Shah, P. M. and Patel, P. S. Role of nitric oxide and antioxidant enzymes in the pathogenesis of oral cancer. Journal of Cancer Research and Therapeutics. 2009. 5, 247-253. [PubMed]
6.
Sainger, R. N., Shah, F. D., Telang, S. D., Shah, P. M. and Patel, P. S. Telomere attrition and telomerase activity are associated with GSTM1 polymorphism in oral cancer. Cancer Biomarkers : Section A of Disease Markers. 2009. 5, 189-195. [PubMed]
7.
Trivedi, P. J., Patel, P. S., Brahmbhatt, M. M., Patel, B. P., Gajjar, S. B., Dalal, E. N., Shukla, S. N., Shah, P. M. and Bakshi, S. R. A new recurring chromosome 13 abnormality in two older patients with de novo acute myeloid leukemia: An Indian experience. Indian Journal of Human Genetics. 2009. 15, 137-139. [PubMed]
8.
Shah, F. D., Shukla, S. N., Shah, P. M. , Shukla, H. K. and Patel, P. S. Clinical significance of matrix metalloproteinase 2 and 9 in breast cancer. Indian Journal of Cancer. 2009. 46, 194-202. [PubMed]
9.
Shah, F. D., Patel, J. B., Shukla, S. N., Shah, P. M. and Patel, P. S. Evaluation of plasma non-enzymatic antioxidants in breast cancer etiology. Asian Pacific Journal of Cancer Prevention : APJCP. 2009. 10, 91-96. [PubMed]
10.
Shah, N. G., Trivedi, T. I., Tankshali, R. A., Goswami, J. V., Jetly, D. H., Shukla, S. N., Shah, P. M. and Verma, R. J. Prognostic significance of molecular markers in oral squamous cell carcinoma: a multivariate analysis. Head & Neck. 2009. 31, 1544-1556. [PubMed]
11.
Vora, H. H., Patel, N. A., Rajvik, K. N., Mehta, S. V., Brahmbhatt, B. V., Shah, M. J., Shukla, S. N. and Shah, P. M. Cytokeratin and vimentin expression in breast cancer. The International Journal of Biological Markers. 2009. 24, 38-46. [PubMed]
12.
Bakshi, S. R., Shukla, S. N. and Shah, P. M. Customized laboratory information management system for a clinical and research leukemia cytogenetics laboratory. Journal of the Association of Genetic Technologists. 2009. 35, 7-8. [PubMed]
13.
Bakshi, S. R., Patel, B. P., Brahmbhatt, M. M., Trivedi, P. J., Gajjar, S. B., Iyer, R. R., Parikh, E. H., Shukla, S. N. and Shah, P. M. Complex karyotype with a masked Philadelphia translocation and variant BCR-ABL fusion in CML. Cancer Genetics and Cytogenetics. 2009. 189, 142-143. [PubMed]
14.
Trivedi, P. J., Patel, P. S., Brahmbhatt, M. M., Patel, B. P., Gajjar, S. B., Iyer, R. R., Parikh, E. H., Shukla, S. N., Shah, P. M. and Bakshi, S. R. A case of acute myeloid leukemia-M2 with trisomy 4 in addition to t(8;21). Indian Journal of Human Genetics. 2008. 14, 20-22. [PubMed]
15.
Shah, M. H., Telang, S. D., Shah, P. M. and Patel, P. S. Tissue and serum alpha 2-3- and alpha 2-6-linkage specific sialylation changes in oral carcinogenesis. Glycoconjugate Journal. 2008. 25, 279-290. [PubMed]
16.
Patel, B. P., Rawal, U. M., Dave, T. K., Rawal, R. M., Shukla, S. N., Shah, P. M. and Patel, P. S. Lipid peroxidation, total antioxidant status, and total thiol levels predict overall survival in patients with oral squamous cell carcinoma. Integrative Cancer Therapies. 2007. 6, 365-372. [PubMed]
17.
Shah, N. G., Trivedi, T. I., Tankshali, R. A., Goswami, J. A., Shah, J. S., Jetly, D. H., Kobawala, T. P., Patel, K. C., Shukla, S. N., Shah, P. M. and Verma, R. J. Molecular alterations in oral carcinogenesis: significant risk predictors in malignant transformation and tumor progression. The International Journal of Biological Markers. 2007. 22, 132-143. [PubMed]
18.
Vora, H. H., Mehta, S. V., Shah, K. N., Brahmbhatt, B. V., Desai, N. S., Shukla, S. N. and Shah, P. M. Cytoplasmic localization of BAG-1 in leukoplakia and carcinoma of the tongue: correlation with p53 and c-erbB2 in carcinoma. The International Journal of Biological Markers. 2007. 22, 100-107. [PubMed]
19.
Patel, B. P., Shah, S. V., Shukla, S. N., Shah, P. M. and Patel, P. S. Clinical significance of MMP-2 and MMP-9 in patients with oral cancer. Head & Neck. 2007. 29, 564-572. [PubMed]
20.
Vora, H. H., Shah, N. G., Trivedi, T. I., Goswami, J. V., Shukla, S. N. and Shah, P. M. Expression of C-Myc mRNA in squamous cell carcinoma of the tongue. Journal of Surgical Oncology. 2007. 95, 70-78. [PubMed]
21.
Bakshi, S. R., Brahmbhatt, M. M., Trivedi, P. J., Shukla, S. N. and Shah, P. M. Atypical D-FISH patterns of BCR/ABL gene rearrangements in 169 chronic myeloid leukemia patients. Journal of the Association of Genetic Technologists. 2006. 32, 164-167. [PubMed]
22.
Bakshi, S. R., Brahmbhatt, M. M., Trivedi, P. J., Gajjar, S. B., Iyer, R. R., Joshi, M. S., Shukla, S. N. and Shah, P. M. Robertsonian translocation (13;14)(q10;q10) in two young male myelodysplastic syndrome patients. Cancer Genetics and Cytogenetics. 2006. 171, 130-131. [PubMed]
23.
Shah, N. G., Trivedi, T. I., Tankshali, R. A., Goswami, J. A., Jetly, D. H., Kobawala, T. P., Shukla, S. N., Shah, P. M. and Verma, R. J. Stat3 expression in oral squamous cell carcinoma: association with clinicopathological parameters and survival. The International Journal of Biological Markers. 2006. 21, 175-183. [PubMed]
24.
Pandey, R., Patel, A., Shah, S., Patel, K. M., Shah, P. M. , Shukla, S. N., Parikh, B. J., Anand, A., Talati, S. S., Panchal, H., Parikh, S. and Thrutthel, S. A rare complication in a case of multiple myeloma on therapy with thalidomide and dexamethasone--reversible posterior lobe leukoencephalopathy. Leukemia & Lymphoma. 2006. 47, 1431-1434. [PubMed]
25.
Vora, H. H., Trivedi, T. I., Shukla, S. N., Shah, N. G., Goswami, J. V. and Shah, P. M. p53 expression in leukoplakia and carcinoma of the tongue. The International Journal of Biological Markers. 2006. 21, 74-80. [PubMed]
26.
Sainger, R. N., Shah, M. H., Desai, A. A., Shukla, S. N., Shah, P. M. , Telang, S. D. and Patel, P. S. Clinical significance of serum p53 antibodies in oral cancer. Tumori. 2006. 92, 134-139. [PubMed]
27.
Patel, B. P., Rawal, U. M., Shah, P. M. , Prajapati, J. A., Rawal, R. M., Dave, T. K. and Patel, P. S. Study of tobacco habits and alterations in enzymatic antioxidant system in oral cancer. Oncology. 2005. 68, 511-519. [PubMed]
28.
Patel, B. P., Shah, P. M. , Rawal, U. M., Desai, A. A., Shah, S. V., Rawal, R. M. and Patel, P. S. Activation of MMP-2 and MMP-9 in patients with oral squamous cell carcinoma. Journal of Surgical Oncology. 2005. 90, 81-88. [PubMed]
29.
Sethi, P. and Shah, P. M. Oral exfoliative cytology of smokers at discrete clinical stages using AgNOR staining. Indian Journal of Dental Research. 2003. 14, 142-145. [PubMed]
30.
Patel, M. M., Parekh, L. J., Jha, F. P., Sainger, R. N., Patel, J. B., Patel, D. D., Shah, P. M. and Patel, P. S. Clinical usefulness of telomerase activation and telomere length in head and neck cancer. Head & Neck. 2002. 24, 1060-1067. [PubMed]
31.
Karelia, N. H., Patel, D. D., Desai, N. S., Mehta, H. V., Yadav, P. K., Patel, S. M., Kothari, K. C. and Shah, P. M. Prognostic significance of DNA aneuploidy and p21 ras oncoprotein expression in colorectal cancer and their role in the determination of treatment modalities. The International Journal of Biological Markers. 2001. 16, 97-104. [PubMed]
32.
Roy, S. K., Trividi, A. H., Bakshi, S. R., Patel, S. J., Shukla, P. S., Shah, A. D., Majithiya, D. B., Patel, D. D. and Shah, P. M. A study of chromosome aneuploidy in hereditary breast cancer patients and their healthy blood relatives. Journal of Experimental & Clinical Cancer Research : CR. 2001. 20, 103-109. [PubMed]
33.
Roy, S. K., Trivedi, A. H., Bakshi, S. R., Patel, S. J., Shukla, P. H., Bhatavdekar, J. M., Patel, D. D. and Shah, P. M. Bleomycin-induced chromosome damage in lymphocytes indicates inefficient DNA repair capacity in breast cancer families. Journal of Experimental & Clinical Cancer Research : CR. 2000. 19, 169-173. [PubMed]
34.
Roy, S. K., Trivedi, A. H., Bakshi, S. R., Patel, R. K., Shukla, P. H., Patel, S. J., Bhatavdekar, J. M., Patel, D. D. and Shah, P. M. Spontaneous chromosomal instability in breast cancer families. Cancer Genetics and Cytogenetics. 2000. 118, 52-56. [PubMed]
35.
Bakshi, S. R., Patel, R. K., Roy, S. K., Alladi, P. A., Trivedi, A. H., Bhatavdekar, J. M., Patel, D. D., Shah, P. M. and Rawal, U. M. Chromosomal aberrations in young cancer patients. Cancer Genetics and Cytogenetics. 1999. 115, 114-117. [PubMed]
36.
Patel, R. K., Trivedi, A. H., Roy, S. K., Bhachech, S. H., Bakshi, S. R., Bhatavdekar, J. M., Desai, C. J., Patel, K. M. and Shah, P. M. A complex translocation involving chromosomes 2, 9 and 22 in a patient with chronic myeloid leukemia. Journal of Experimental & Clinical Cancer Research : CR. 1998. 17, 443-444. [PubMed]
37.
Patel, R. K., Trivedi, A. H., Roy, S. K., Bhatavdekar, J. M., Shah, P. M. and Patel, D. D. Influence of alpha-tocopherol and ascorbic acid on pan masala induced genomic damage. An in vitro experiment. Journal of Experimental & Clinical Cancer Research : CR. 1998. 17, 419-424. [PubMed]
38.
Bakshi, S. R., Patel, R. K., Roy, S. K., Alladi, P., Trivedi, A. H., Bhatavdekar, J. M., Patel, D. D., Shah, P. M. and Rawal, U. M. Mitomycin C induced chromosomal aberrations in young cancer patients. Mutation Research. 1998. 422, 223-228. [PubMed]
39.
Patel, R. K., Trivedi, A. H., Jaju, R. J., Kukreti, M. S., Bhatavdekar, J. M., Shah, P. M. and Patel, D. D. Protection from pan masala induced genomic damage by beta-carotene and retinoic acid--an in vitro experience. Neoplasma. 1998. 45, 169-175. [PubMed]
40.
Trivedi, A. H., Balar, D. B., Shah, P. M. , Patel, D. D., Patel, R. K., Bakshi, S. R. and Dinavahi, V. B. Carcinogenic and genotoxic effects of the tobacco substitute pan masala: present status and likely future impact on the Indian population. Cancer Treatment Reviews. 1996. 22, 345-354. [PubMed]
41.
Neema, J. P., Baboo, H. A. and Shah, P. M. Radiation mucositis: prevention and treatment with special reference to the use of GM-CSF. The Journal of the Association of Physicians of India. 1995. Suppl 3, 14. [PubMed]
42.
Patel, P. S., Raval, G. N., Rawal, R. M., Patel, G. H., Balar, D. B., Shah, P. M. and Patel, D. D. Comparison between serum levels of carcinoembryonic antigen, sialic acid and phosphohexose isomerase in lung cancer. Neoplasma. 1995. 42, 271-274. [PubMed]
43.
Patel, P. S., Raval, G. N., Rawal, R. R., Patel, G. H., Balar, D. B., Shah, P. M. and Patel, D. D. Assessing benefits of combining biochemical and immunological markers in patients with lung carcinoma. Cancer Letters. 1994. 82, 129-133. [PubMed]
44.
Patel, P. S., Adhvaryu, S. G., Balar, D. B., Parikh, B. J. and Shah, P. M. Clinical application of serum levels of sialic acid, fucose and seromucoid fraction as tumour markers in human leukemias. Anticancer Research. 1994. 14, 747-751. [PubMed]
45.
Patel, A. P., Kothari, J. M., Patel, K. M., Shukla, S. N., Shah, R. B., Anand, A., Parikh, B. J., Giri, D. D. and Shah, P. M. Retroperitoneal lymphangioma. Indian Journal of Pediatrics. 1994. 61, 194-197. [PubMed]
46.
Anand, A. S., Shah, P. M. , Parikh, B. J., Shah, S. A., Patel, K. M., Shukla, S. N., Talati, S. S. and Patel, A. R. Recombinant alpha-interferon therapy in multiple myeloma. Indian Journal of Cancer. 1990. 27, 203-207. [PubMed]
Grant Support:
Project Title
Role
Funding Agency
Sanction Number
Sanction Date
Identification of Glucose non-fermenting gram-negative rods isolation from infected cancer patients
Co-PI
Gujarat Cancer Society, India
Characterization of chromosome rearrangements of malignant effusions with multiplex-FISH
Co-PI
The Gujarat State Biotechnology Mission, India
Acute lymphocytic leukemia: A cytogenetic exploration
Co-PI
Gujarat Cancer Society, India
Acute Myeloid Leukemia: A cytogenetic exploration
Co-PI
Gujarat Cancer Society, India
Chronic Myeloid Leukemia: A cytogenetic exploration
Co-PI
Gujarat Cancer Society, India
Detection of BCR-ABL gene by polymerase chain reaction in chronic myeloid leukemia (CML) and differential diagnosis of lymphoid leukemia
Co-PI
Directorate of Medical Education and Research
Immunochemical substances in thyroid disorders and thyroid malignancies
Co-PI
Gujarat Cancer Society, India
Understanding involvement of several molecules in thyroid tumorigenesis
Co-PI
Directorate of Medical Education and Research
Clinical utility of p27 in colorectal carcinoma
Co-PI
Directorate of Medical Education and Research
Soluble Fas and Fas ligand in autoimmune thyroid disorders
Co-PI
Directorate of Medical Education and Research
Clinical significance of Stat1 and Stat3 expression in breast cancer
Co-PI
Directorate of Medical Education and Research
Role of Stat5 and Stat6 in oral squamous cell carcinoma
Co-PI
Directorate of Medical Education and Research
Clinical relevance of negative regulators of Stats in oral squamous cell carcinoma
Co-PI
Gujarat Cancer Society, India
Expression of Fas receptor mRNA and Fas ligand mRNA in patients with colorectal carcinoma
Co-PI
Directorate of Medical Education and Research
Role of SPARC receptor mRNA and Vitamin D receptor mRNA in colorectal cancer
Co-PI
Directorate of Medical Education and Research
Role of microsatellite markers in patients with adenomatous polyps and colorectal carcinoma
Co-PI
Gujarat Cancer Society, India
Role of SRC family kinases in oral squamous cell carcinoma
Co-PI
Directorate of Medical Education and Research
Role of Stats in detection of lymph node micrometastasis in early stage oral squamous cell carcinoma patients
Co-PI
Gujarat Cancer Society, India
Multi-parametric approach to predict treatment outcome in patients with malignant solid tumors undergoing primary radiotherapy
Co-PI
Department of Atomic Energy, Government of India
Study of GST-T1, GST-M1 and CYP1A1 polymorphisms in oral cancer
Co-PI
Directorate of Medical Education and Research
Study of Molecular mechanism in head and neck cancer
Co-PI
Gujarat Cancer Society, India
E-cadherin expression as marker for invasion and metastasis in breast cancer
Co-PI
Directorate of Medical Education and Research
Role of nitric oxide and its associated biomarkers in oral cancer
Co-PI
Directorate of Medical Education and Research
Role of E-cadherin expression in oral cancer progression and metastasis
Co-PI
Gujarat Cancer Society, India
Study of cellular retinol-binding protein-1 and retinoic acid receptor-beta in breast cancer
Co-PI
Gujarat Cancer Society, India
Study of Her-2 neu expression in breast cancer and its correlation with ER, PR, clinicopathological parameters and treatment
Co-PI
Gujarat Cancer Society, India
FLT3 Expression in acute myeloid leukaemia
Co-PI
Gujarat Cancer Society, India
A study of apoptosis-related proetin expression in minimal residual disease in acute myeloid leukaemia by flow cytometry
Co-PI
Gujarat Cancer Society, India
A study of methylation of tumor suppressor gene PTEN in patients with breast cancer
Principal Investigator
Gujarat Cancer Society, India
Epithelial mesenchymal transition in breast cancer: Role of PRL-3 mediated PI3K-AKT pathway
Principal Investigator
Gujarat Cancer Society, India
A study of Gamma-Delta T cells in patients with leukoplakia and oral carcinoma by flow cytometry
Principal Investigator
Directorate of Medical Education and Research
A conventional and molecular cytogenetic analysis of Philadelphia chromosome and variants in chronic myeloid leukemia patients
Co-PI
The Gujarat Council of Science and Technology, India
Rural cancer registry project, Ahmedabad district
Principal Investigator
National Cancer Registry Programme, Indian Council of Medical Research, India
Ahmedabad district cancer control programme
Principal Investigator
National Cancer Control Programme, Government of India
Population based cancer registry - Ahmedabad urban agglomeration area
Principal Investigator
National Cancer Registry Programme, Indian Council of Medical Research, India
Development of an atlas of cancer in Gujarat
Principal Investigator
Government of Gujarat, India
Statewide cancer screening programme
Principal Investigator
Government of Gujarat, India
Education
::
M.D.
Honors and Awards
::
Dr. BC Roy Award
Type of Neoplasms
Gastrointestinal tract
Colon