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Dulal Panda, Ph.D.
Indian Institute of Technology Bombay
Department of Biosciences and Bioengineering
Mumbai - 400 076   
Phone: +91-22-25767838, 25722545, Extn. 7838
Fax: +91-22-25723480
Positions Held:
Position Affiliation Time Period
Professor Indian Institute of Technology Bombay, Mumbai, India 2007-Present
Associate Professor Indian Institute of Technology Bombay, Mumbai, India 2003-2007
Assistant Professor Indian Institute of Technology Bombay, Mumbai, India 2000-2003
Assistant Research Biologist University of California, Santa Barbara, USA 1998-2000
Area of Specialization:
Molecular Biology
Research Summary:
Elucidating the role of microtubule dynamics in cellular processes and microtubule targeted drugs including anti-cancer and anti-fungal drugs
Polymerization dynamics of bacterial cell division protein, FtsZ
Characterization of yeast and plant tubulins to understand the molecular specificity of microtubule targeted anti-fungal and anti-parasitic drug
Structure function studies of microtubule associated protein Tau
Protein folding
1. Chatterji, B. P., Jindal, B., Srivastava, S. and Panda, D.  Microtubules as antifungal and antiparasitic drug targets. Expert Opinion On Therapeutic Patents. 2011.  21, 167-186. [PubMed]
2. Balakrishna, M. S., Suresh, D., Rai, A., Mague, J. T. and Panda, D.  Dinuclear copper(I) complexes containing cyclodiphosphazane derivatives and pyridyl ligands: synthesis, structural studies, and antiproliferative activity toward human cervical and breast cancer cells. Inorganic Chemistry. 2010.  49, 8790-8801. [PubMed]
3. Chatterji, B. P., Banerjee, M., Singh, P. and Panda, D.  Corrigendum to "HMBA depolymerizes microtubules, activates mitotic checkpoints and induces mitotic block in MCF-7 cells by binding at the colchicine site in tubulin" [Biochem. Pharmacol. 80 (2010) 50-61]. Biochemical Pharmacology. 2010.  80, 1113. [PubMed]
4. Jaiswal, R., Patel, R. Y., Asthana, J., Jindal, B., Balaji, P. V. and Panda, D.  E93R substitution of Escherichia coli FtsZ induces bundling of protofilaments, reduces GTPase activity, and impairs bacterial cytokinesis. The Journal of Biological Chemistry. 2010.  285, 31796-31805. [PubMed]
5. Banerjee, M., Singh, P. and Panda, D.  Curcumin suppresses the dynamic instability of microtubules, activates the mitotic checkpoint and induces apoptosis in MCF-7 cells. The FEBS Journal. 2010.  277, 3437-3448. [PubMed]
6. Kaur, S., Modi, N. H., Panda, D. and Roy, N.  Probing the binding site of curcumin in Escherichia coli and Bacillus subtilis FtsZ--a structural insight to unveil antibacterial activity of curcumin. European Journal of Medicinal Chemistry. 2010.  45, 4209-4214. [PubMed]
7. Singh, P. and Panda, D.  FtsZ inhibition: a promising approach for antistaphylococcal therapy. Drug News & Perspectives. 2010.  23, 295-304. [PubMed]
8. Rathinasamy, K., Jindal, B., Asthana, J., Singh, P., Balaji, P. V. and Panda, D.  Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine. BMC Cancer. 2010.  10, 213. [PubMed]
9. Bhattacharyya, B., Kapoor, S. and Panda, D.  Fluorescence spectroscopic methods to analyze drug-tubulin interactions. Methods in Cell Biology. 2010.  95, 301-329. [PubMed]
10. Chatterji, B. P., Banerjee, M., Singh, P. and Panda, D.  HMBA depolymerizes microtubules, activates mitotic checkpoints and induces mitotic block in MCF-7 cells by binding at the colchicine site in tubulin. Biochemical Pharmacology. 2010.  80, 50-61. [PubMed]
11. Kuchibhatla, A., Abdul, R., Narayanan, J., Bellare, J. and Panda, D.  An analysis of FtsZ assembly using small angle X-ray scattering and electron microscopy. Langmuir . 2009.  25, 3775-3785. [PubMed]
12. Kapoor, S. and Panda, D.  Targeting FtsZ for antibacterial therapy: a promising avenue. Expert Opinion On Therapeutic Targets. 2009.  13, 1037-1051. [PubMed]
13. Jaiswal, R. and Panda, D.  Differential assembly properties of Escherichia coli FtsZ and Mycobacterium tuberculosis FtsZ: an analysis using divalent calcium. Journal of Biochemistry. 2009.  146, 733-742. [PubMed]
14. Burai, T. N., Mukherjee, T. K., Lahiri, P., Panda, D. and Datta, A.  Early events associated with the excited state proton transfer in 2-(2'-pyridyl)benzimidazole. The Journal of Chemical Physics. 2009.  131, 034504. [PubMed]
15. Beuria, T. K., Singh, P., Surolia, A. and Panda, D.  Promoting assembly and bundling of FtsZ as a strategy to inhibit bacterial cell division: a new approach for developing novel antibacterial drugs. The Biochemical Journal. 2009.  423, 61-69. [PubMed]
16. Srivastava, R. K., Jaiswal, R., Panda, D. and Wangikar, P. P.  Megacell phenotype and its relation to metabolic alterations in transketolase deficient strain of Bacillus pumilus. Biotechnology and Bioengineering. 2009.  102, 1387-1397. [PubMed]
17. Rathinasamy, K. and Panda, D.  Kinetic stabilization of microtubule dynamic instability by benomyl increases the nuclear transport of p53. Biochemical Pharmacology. 2008.  76, 1669-1680. [PubMed]
18. Singh, J. K., Makde, R. D., Kumar, V. and Panda, D.  SepF increases the assembly and bundling of FtsZ polymers and stabilizes FtsZ protofilaments by binding along its length. The Journal of Biological Chemistry. 2008.  283, 31116-31124. [PubMed]
19. Mohan, R. and Panda, D.  Kinetic stabilization of microtubule dynamics by estramustine is associated with tubulin acetylation, spindle abnormalities, and mitotic arrest. Cancer Research. 2008.  68, 6181-6189. [PubMed]
20. Jaiswal, R. and Panda, D.  Cysteine 155 plays an important role in the assembly of Mycobacterium tuberculosis FtsZ. Protein Science. 2008.  17, 846-854. [PubMed]
21. Suresh, D., Balakrishna, M. S., Rathinasamy, K., Panda, D. and Mague, J. T.  Large-bite bis(phosphite) ligand containing mesocyclic thioether moieties: synthesis, reactivity, group 11 (Cu(I), Au(I)) metal complexes and anticancer activity studies on a human cervical cancer (HeLa) cell line. Dalton Transactions. 2008.  , 2285-2292. [PubMed]
22. Singh, P., Rathinasamy, K., Mohan, R. and Panda, D.  Microtubule assembly dynamics: an attractive target for anticancer drugs. IUBMB Life. 2008.  60, 368-375. [PubMed]
23. Panda, D. and Datta, A.  Implications of area normalization of multi-component spectra. Applied Spectroscopy. 2008.  62, 341-344. [PubMed]
24. Ray, S., Mohan, R., Singh, J. K., Samantaray, M. K., Shaikh, M. M., Panda, D. and Ghosh, P.  Anticancer and antimicrobial metallopharmaceutical agents based on palladium, gold, and silver N-heterocyclic carbene complexes. Journal of the American Chemical Society. 2007.  129, 15042-15053. [PubMed]
25. Rai, D., Singh, J. K., Roy, N. and Panda, D.  Curcumin inhibits FtsZ assembly: an attractive mechanism for its antibacterial activity. The Biochemical Journal. 2008.  410, 147-155. [PubMed]
26. Prasad, N. K., Rathinasamy, K., Panda, D. and Bahadur, D.  TC-tuned biocompatible suspension of La0.73Sr0.27MnO3 for magnetic hyperthermia. Journal of Biomedical Materials Research. 2008.  85, 409-416. [PubMed]
27. Singh, J. K., Makde, R. D., Kumar, V. and Panda, D.  A membrane protein, EzrA, regulates assembly dynamics of FtsZ by interacting with the C-terminal tail of FtsZ. Biochemistry. 2007.  46, 11013-11022. [PubMed]
28. Srivastava, P. and Panda, D.  Rotenone inhibits mammalian cell proliferation by inhibiting microtubule assembly through tubulin binding. The FEBS Journal. 2007.  274, 4788-4801. [PubMed]


Ph.D. Bose Institute, Kolkata, India
Honors and Awards
2008, Fellow of the Indian Academy of Sciences
2007, P.S. Sarma Memorial Award from the Society of Biological Chemists, India
2007, Member of Guha Research Conference
2005, Fellow of National Acadamy of Sciences, India
2005, National Bioscience Award
2004, Swarna Jayanti Fellowship
2001, Fogarty International Reasearch Award, NIH, USA
1999, International Research Award from CAP-CURE, USA
  Last modified on : Mar 4, 2011
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