INCREDB ID : 14
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Dulal Panda, Ph.D.
Professor 
 
Indian Institute of Technology Bombay
Department of Biosciences and Bioengineering
Powai
Mumbai - 400 076   
Maharashtra   
 
E-mail: panda@iitb.ac.in
Phone: +91-22-25767838, 25722545, Extn. 7838
Fax: +91-22-25723480
 
URL: http://www.btc.iitb.ac.in/~panda/
 
Positions Held:
Position Affiliation Time Period
Professor Indian Institute of Technology Bombay, Mumbai, India 2007-Present
Associate Professor Indian Institute of Technology Bombay, Mumbai, India 2003-2007
Assistant Professor Indian Institute of Technology Bombay, Mumbai, India 2000-2003
Assistant Research Biologist University of California, Santa Barbara, USA 1998-2000
 
Area of Specialization:
Molecular Biology
Research Summary:
Elucidating the role of microtubule dynamics in cellular processes and microtubule targeted drugs including anti-cancer and anti-fungal drugs
Polymerization dynamics of bacterial cell division protein, FtsZ
Characterization of yeast and plant tubulins to understand the molecular specificity of microtubule targeted anti-fungal and anti-parasitic drug
Structure function studies of microtubule associated protein Tau
Protein folding
 
Publications:
1. Chatterji, B. P., Jindal, B., Srivastava, S. and Panda, D.  Microtubules as antifungal and antiparasitic drug targets. Expert Opinion On Therapeutic Patents. 2011.  21, 167-186. [PubMed]
2. Balakrishna, M. S., Suresh, D., Rai, A., Mague, J. T. and Panda, D.  Dinuclear copper(I) complexes containing cyclodiphosphazane derivatives and pyridyl ligands: synthesis, structural studies, and antiproliferative activity toward human cervical and breast cancer cells. Inorganic Chemistry. 2010.  49, 8790-8801. [PubMed]
3. Chatterji, B. P., Banerjee, M., Singh, P. and Panda, D.  Corrigendum to "HMBA depolymerizes microtubules, activates mitotic checkpoints and induces mitotic block in MCF-7 cells by binding at the colchicine site in tubulin" [Biochem. Pharmacol. 80 (2010) 50-61]. Biochemical Pharmacology. 2010.  80, 1113. [PubMed]
4. Jaiswal, R., Patel, R. Y., Asthana, J., Jindal, B., Balaji, P. V. and Panda, D.  E93R substitution of Escherichia coli FtsZ induces bundling of protofilaments, reduces GTPase activity, and impairs bacterial cytokinesis. The Journal of Biological Chemistry. 2010.  285, 31796-31805. [PubMed]
5. Banerjee, M., Singh, P. and Panda, D.  Curcumin suppresses the dynamic instability of microtubules, activates the mitotic checkpoint and induces apoptosis in MCF-7 cells. The FEBS Journal. 2010.  277, 3437-3448. [PubMed]
6. Kaur, S., Modi, N. H., Panda, D. and Roy, N.  Probing the binding site of curcumin in Escherichia coli and Bacillus subtilis FtsZ--a structural insight to unveil antibacterial activity of curcumin. European Journal of Medicinal Chemistry. 2010.  45, 4209-4214. [PubMed]
7. Singh, P. and Panda, D.  FtsZ inhibition: a promising approach for antistaphylococcal therapy. Drug News & Perspectives. 2010.  23, 295-304. [PubMed]
8. Rathinasamy, K., Jindal, B., Asthana, J., Singh, P., Balaji, P. V. and Panda, D.  Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine. BMC Cancer. 2010.  10, 213. [PubMed]
9. Bhattacharyya, B., Kapoor, S. and Panda, D.  Fluorescence spectroscopic methods to analyze drug-tubulin interactions. Methods in Cell Biology. 2010.  95, 301-329. [PubMed]
10. Chatterji, B. P., Banerjee, M., Singh, P. and Panda, D.  HMBA depolymerizes microtubules, activates mitotic checkpoints and induces mitotic block in MCF-7 cells by binding at the colchicine site in tubulin. Biochemical Pharmacology. 2010.  80, 50-61. [PubMed]
11. Kuchibhatla, A., Abdul, R., Narayanan, J., Bellare, J. and Panda, D.  An analysis of FtsZ assembly using small angle X-ray scattering and electron microscopy. Langmuir . 2009.  25, 3775-3785. [PubMed]
12. Kapoor, S. and Panda, D.  Targeting FtsZ for antibacterial therapy: a promising avenue. Expert Opinion On Therapeutic Targets. 2009.  13, 1037-1051. [PubMed]
13. Jaiswal, R. and Panda, D.  Differential assembly properties of Escherichia coli FtsZ and Mycobacterium tuberculosis FtsZ: an analysis using divalent calcium. Journal of Biochemistry. 2009.  146, 733-742. [PubMed]
14. Burai, T. N., Mukherjee, T. K., Lahiri, P., Panda, D. and Datta, A.  Early events associated with the excited state proton transfer in 2-(2'-pyridyl)benzimidazole. The Journal of Chemical Physics. 2009.  131, 034504. [PubMed]
15. Beuria, T. K., Singh, P., Surolia, A. and Panda, D.  Promoting assembly and bundling of FtsZ as a strategy to inhibit bacterial cell division: a new approach for developing novel antibacterial drugs. The Biochemical Journal. 2009.  423, 61-69. [PubMed]
16. Srivastava, R. K., Jaiswal, R., Panda, D. and Wangikar, P. P.  Megacell phenotype and its relation to metabolic alterations in transketolase deficient strain of Bacillus pumilus. Biotechnology and Bioengineering. 2009.  102, 1387-1397. [PubMed]
17. Rathinasamy, K. and Panda, D.  Kinetic stabilization of microtubule dynamic instability by benomyl increases the nuclear transport of p53. Biochemical Pharmacology. 2008.  76, 1669-1680. [PubMed]
18. Singh, J. K., Makde, R. D., Kumar, V. and Panda, D.  SepF increases the assembly and bundling of FtsZ polymers and stabilizes FtsZ protofilaments by binding along its length. The Journal of Biological Chemistry. 2008.  283, 31116-31124. [PubMed]
19. Mohan, R. and Panda, D.  Kinetic stabilization of microtubule dynamics by estramustine is associated with tubulin acetylation, spindle abnormalities, and mitotic arrest. Cancer Research. 2008.  68, 6181-6189. [PubMed]
20. Jaiswal, R. and Panda, D.  Cysteine 155 plays an important role in the assembly of Mycobacterium tuberculosis FtsZ. Protein Science. 2008.  17, 846-854. [PubMed]
21. Suresh, D., Balakrishna, M. S., Rathinasamy, K., Panda, D. and Mague, J. T.  Large-bite bis(phosphite) ligand containing mesocyclic thioether moieties: synthesis, reactivity, group 11 (Cu(I), Au(I)) metal complexes and anticancer activity studies on a human cervical cancer (HeLa) cell line. Dalton Transactions. 2008.  , 2285-2292. [PubMed]
22. Singh, P., Rathinasamy, K., Mohan, R. and Panda, D.  Microtubule assembly dynamics: an attractive target for anticancer drugs. IUBMB Life. 2008.  60, 368-375. [PubMed]
23. Panda, D. and Datta, A.  Implications of area normalization of multi-component spectra. Applied Spectroscopy. 2008.  62, 341-344. [PubMed]
24. Ray, S., Mohan, R., Singh, J. K., Samantaray, M. K., Shaikh, M. M., Panda, D. and Ghosh, P.  Anticancer and antimicrobial metallopharmaceutical agents based on palladium, gold, and silver N-heterocyclic carbene complexes. Journal of the American Chemical Society. 2007.  129, 15042-15053. [PubMed]
25. Rai, D., Singh, J. K., Roy, N. and Panda, D.  Curcumin inhibits FtsZ assembly: an attractive mechanism for its antibacterial activity. The Biochemical Journal. 2008.  410, 147-155. [PubMed]
26. Prasad, N. K., Rathinasamy, K., Panda, D. and Bahadur, D.  TC-tuned biocompatible suspension of La0.73Sr0.27MnO3 for magnetic hyperthermia. Journal of Biomedical Materials Research. 2008.  85, 409-416. [PubMed]
27. Singh, J. K., Makde, R. D., Kumar, V. and Panda, D.  A membrane protein, EzrA, regulates assembly dynamics of FtsZ by interacting with the C-terminal tail of FtsZ. Biochemistry. 2007.  46, 11013-11022. [PubMed]
28. Srivastava, P. and Panda, D.  Rotenone inhibits mammalian cell proliferation by inhibiting microtubule assembly through tubulin binding. The FEBS Journal. 2007.  274, 4788-4801. [PubMed]

 
 
Education 
::
Ph.D. Bose Institute, Kolkata, India
Honors and Awards
::
2008, Fellow of the Indian Academy of Sciences
::
2007, P.S. Sarma Memorial Award from the Society of Biological Chemists, India
::
2007, Member of Guha Research Conference
::
2005, Fellow of National Acadamy of Sciences, India
::
2005, National Bioscience Award
::
2004, Swarna Jayanti Fellowship
::
2001, Fogarty International Reasearch Award, NIH, USA
::
1999, International Research Award from CAP-CURE, USA
  Last modified on : Mar 4, 2011
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.