Ashok Sehgal, M.D.
Institute of Cytology and Preventive Oncology
I-7, Sector-39
Noida - 201 301
Uttar Pradesh
E-mail: sehgalashok54@yahoo.co.in
URL: http://www.icmr.nic.in/icmrsql/biodata.asp?expno=00015036
Positions Held:
Position Affiliation Time Period
Director-in-Charge
Institute of Cytology and Preventive Oncology, Noida, India
Present
Deputy Director (Senior Grade)
Institute of Cytology and Preventive Oncology, Noida, India
1999-Present
Deputy Director
Institute of Cytology and Preventive Oncology, Noida, India
1993-1998
Assistant Director
Institute of Cytology and Preventive Oncology, Noida, India
1985-1992
Senior Research Officer
National Institute of Virology, Pune, India
1981-1985
Area of Specialization:
Cancer Epidemiology
Research Summary:
First one to have discovered water borne non-A, non-B hepatitis ( hepatitis E)
First one to have evaluated the sero-response to hepatitis B vaccine during and epidemic in Ahmedabad
Evaluated viral markers for the detection and progression of viral hepatitis
Evaluated indigenous ELISA kits for detection of hepatitis B surface antigen and surface antibodies for its sensitivity and specificity
First one to have evolved alternative strategies for early detection of cervical cancer
Designated as Expert Resource Personnel by WHO for alternative strategies for early detection of cervical cancer
Natural History of Cervical cancer and Biological behaviour of dysplasias
Multimodal screening for cervical cancer
Publications:
1.
Khan, M. A., Bahadur, A. K., Agarwal, P. N., Sehgal, A. and Das, B. C. Psychosocial disorders in women undergoing postoperative radiation and chemotherapy for breast cancer in India. Indian Journal of Cancer. 2010. 47, 296-303. [PubMed]
2.
Yadav, S. P., Kharya, G., Mohan, N., Sehgal, A. , Bhat, S., Jain, S., Kapoor, G. and Sachdeva, A. Langerhans cell histiocytosis with digestive tract involvement. Pediatric Blood & Cancer. 2010. 55, 748-753. [PubMed]
3.
Sehgal, A. and Singh, V. Human papillomavirus infection (HPV) & screening strategies for cervical cancer. The Indian Journal of Medical Research. 2009. 130, 234-240. [PubMed]
4.
Sehgal, A. , Gupta, S., Parashari, A., Sodhani, P. and Singh, V. Urine HPV-DNA detection for cervical cancer screening: prospects and prejudices. Journal of Obstetrics and Gynaecology. 2009. 29, 583-589. [PubMed]
5.
Sardana, S., Sharma, S., Sodhani, P., Sehgal, A. and DAS, B. C. An epidemiological study to identify the risk factors with two different types of controls in high-grade cervical lesions including invasive cancer. European Journal of Cancer Care. 2009. 18, 620-624. [PubMed]
6.
Gupta, S., Sodhani, P., Sharma, A., Sharma, J. K., Halder, K., Charchra, K. L., Sardana, S., Singh, V., Sehgal, A. and Das, B. C. Prevalence of high-risk human papillomavirus type 16/18 infection among women with normal cytology: risk factor analysis and implications for screening and prophylaxis. Cytopathology. 2009. 20, 249-255. [PubMed]
7.
Gupta, S., Sodhani, P., Chachra, K. L., Singh, V. and Sehgal, A. Outcome of "Atypical squamous cells" in a cervical cytology screening program: implications for follow up in resource limited settings. Diagnostic Cytopathology. 2007. 35, 677-680. [PubMed]
8.
Gupta, S., Sodhani, P., Halder, K., Chachra, K. L., Singh, V. and Sehgal, A. Age trends in pre-cancerous and cancerous lesions of the uterine cervix in a cytology screening programme: what should be the target age group for a major thrust of screening in resource-limited settings? Cytopathology. 2008. 19, 106-110. [PubMed]
9.
Juneja, A., Sehgal, A. , Sharma, S. and Pandey, A. Cervical cancer screening in India: strategies revisited. Indian Journal of Medical Sciences. 2007. 61, 34-47. [PubMed]
10.
Sodhani, P., Gupta, S., Sharma, J. K., Parashari, A., Halder, K., Singh, V. and Sehgal, A. Test characteristics of various screening modalities for cervical cancer: a feasibility study to develop an alternative strategy for resource-limited settings. Cytopathology. 2006. 17, 348-352. [PubMed]
11.
Gupta, S., Sodhani, P., Halder, K., Chachra, K. L., Sardana, S., Singh, V. and Sehgal, A. Spectrum of epithelial cell abnormalities of uterine cervix in a cervical cancer screening programme: implications for resource limited settings. European Journal of Obstetrics, Gynecology, and Reproductive Biology. 2007. 134, 238-242. [PubMed]
12.
Sodhani, P., Gupta, S., Singh, V., Sehgal, A. , Halder, K. and Parashari, A. Sensitivity of the Pap test in detecting high grade lesions: what should be the acceptable cytologic threshold for colposcopic referral? Acta Cytologica. 2006. 50, 181-184. [PubMed]
13.
Sehgal A. Continuous positive airway pressure-a gentler approach to ventilation. Indian Pediatrics. 2005. 42, 393-394. [PubMed]
14.
Sodhani, P., Gupta, S., Singh, V., Sehgal, A. and Mitra, A. B. Eliminating the diagnosis atypical squamous cells of undetermined significance: impact on the accuracy of the Papanicolaou test. Acta Cytologica. 2004. 48, 783-787. [PubMed]
15.
Sehgal, A. , Telang, S., Passah, S. M. and Jyothi, M. C. Maternal and neonatal profile and immediate outcome in extremely low birth weight babies in Delhi. Tropical Doctor. 2004. 34, 165-168. [PubMed]
16.
Gupta, K., Sehgal, A. , Sircar, M., Jaiswal, A. and Arora, V. K. Giant thymolipoma--a rare mediastinal tumour: a case report. Indian Journal of Pathology & Microbiology. 2003. 46, 231-232. [PubMed]
17.
Sodhani, P., Gupta, S., Sehgal, A. , Singh, V., Khan, I. U. and Mitra, A. B. Atypical squamous cells of undetermined significance: is it worthwhile to qualify them further? Indian Journal of Cancer. 2003. 40, 23-26. [PubMed]
18.
Juneja, A., Sehgal, A. , Mitra, A. B. and Pandey, A. A survey on risk factors associated with cervical cancer. Indian Journal of Cancer. 2003. 40, 15-22. [PubMed]
19.
Sehgal, A. , Singh, V., Chandra, J. and Mathur, N. N. Foreign body aspiration. Indian Pediatrics. 2002. 39, 1006-1010. [PubMed]
20.
Gupta, K., Sehgal, A. , Puri, M. M. and Sidhwa, H. K. Microfilariae in association with other diseases. A report of six cases. Acta Cytologica. 2002. 46, 776-778. [PubMed]
21.
Sehgal, A. , Singh, V., Agarwal, K., Pahuja, S., Chaddha, R. and Chandra, J. Neuroglial cyst: a rare occurence in abdomen and pelvis. Indian Journal of Pathology & Microbiology. 2001. 44, 475-477. [PubMed]
22.
Sehgal, A. , Dubey, N. K., Jyothi, M. C. and Jain, S. Comparison of tympanic and rectal temperature in febrile patients. Indian Journal of Pediatrics. 2002. 69, 305-308. [PubMed]
23.
Sehgal, A. , Chandra, J., Singh, V., Dutta, A. K. and Bagga, D. Congenital diaphragmatic hernia: delayed presentation with asymptomatic spleenic herniation. The Indian Journal of Chest Diseases & Allied Sciences. 2002. 44, 57-60. [PubMed]
24.
Singh, V., Sehgal, A. , Parashari, A., Sodhani, P. and Satyanarayana, L. Early detection of cervical cancer through acetic acid application--an aided visual inspection. Singapore Medical Journal. 2001. 42, 351-354. [PubMed]
25.
Sehgal, A. , Roy, M. S., Dubey, N. K. and Jyothi, M. C. Factors contributing to outcome in newborns delivered out of hospital and referred to a teaching institution. Indian Pediatrics. 2001. 38, 1289-1294. [PubMed]
26.
Dutta, A. K. and Sehgal, A. Combination vaccines: an exciting world. Indian Journal of Pediatrics. 2001. 68 Suppl 1, S44-9. [PubMed]
27.
Parashari, A., Singh, V., Sehgal, A. , Satyanarayana, L., Sodhani, P. and Gupta, M. M. Low-cost technology for screening uterine cervical cancer. Bulletin of the World Health Organization. 2000. 78, 964-967. [PubMed]
28.
Singh, V., Parashari, A., Satyanarayana, L., Sodhani, P., Gupta, M. M. and Sehgal, A. Biological behavior and etiology of inflammatory cervical smears. Diagnostic Cytopathology. 1999. 20, 199-202. [PubMed]
29.
Parashari, A., Singh, V., Gupta, M. M., Satyanararayana, L., Chattopadhya, D. and Sehgal, A. Mutagenicity of endocervical mucus associated with genital tract infections. Cancer Detection and Prevention. 1996. 20, 597-600. [PubMed]
30.
Parashari, A., Singh, V., Gupta, M. M., Satyanarayana, L., Chattopadhya, D., Sodhani, P. and Sehgal, A. Significance of inflammatory cervical smears. APMIS : Acta Pathologica, Microbiologica, et Immunologica Scandinavica. 1995. 103, 273-278. [PubMed]
31.
Singh, V., Sehgal, A. , Satyanarayana, L., Gupta, M. M., Parashari, A. and Chattopadhya, D. Clinical presentation of gynecologic infections among Indian women. Obstetrics and Gynecology. 1995. 85, 215-219. [PubMed]
32.
Singh, V., Gupta, M. M., Satyanarayana, L., Parashari, A., Sehgal, A. , Chattopadhya, D. and Sodhani, P. Association between reproductive tract infections and cervical inflammatory epithelial changes. Sexually Transmitted Diseases. 1995. 22, 25-30. [PubMed]
33.
Singh, V., Sehgal, A. , Gupta, M. M., Satyanarayan, L., Parashari, A., Sodhani, P. and Chattopadhya, D. Bleeding ectopy as an indicator for genital tract infections. Genitourinary Medicine. 1994. 70, 424. [PubMed]
34.
Gopinath, N., Chadha, S. L., Sehgal, A. , Shekhawat, S. and Tandon, R. What is 'desirable' lipid profile. Indian Heart Journal. 1994. 46, 325-327. [PubMed]
35.
Sardana, S., Sodhani, P., Agarwal, S. S., Sehgal, A. , Roy, M., Singh, V., Bhatnagar, P. and Murthy, N. S. Epidemiologic analysis of Trichomonas vaginalis infection in inflammatory smears. Acta Cytologica. 1994. 38, 693-697. [PubMed]
36.
Agarwal, S. S., Sehgal, A. , Sardana, S., Kumar, A. and Luthra, U. K. Role of male behavior in cervical carcinogenesis among women with one lifetime sexual partner. Cancer. 1993. 72, 1666-1669. [PubMed]
37.
Dhamija, S., Sehgal, A. , Luthra, U. K. and Sehgal, K. Factors associated with awareness and knowledge of cervical cancer in a community: implication for health education programmes in developing countries. Journal of the Royal Society of Health. 1993. 113, 184-186. [PubMed]
38.
Sehgal, A. , Sehgal, R., Gupta, I., Bhakoo, O. N. and Ganguly, N. K. Use of hepatitis B vaccine alone or in combination with hepatitis B immunoglobulin for immunoprophylaxis of perinatal hepatitis B infection. Journal of Tropical Pediatrics. 1992. 38, 247-251. [PubMed]
39.
Sehgal, A. , Gupta, I., Sehgal, R. and Ganguly, N. K. Hepatitis B vaccine alone or in combination with anti-HBs immunoglobulin in the perinatal prophylaxis of babies born to HBsAg carrier mothers. Acta Virologica. 1992. 36, 359-366. [PubMed]
40.
Singh, V., Sehgal, A. and Luthra, U. K. Screening for cervical cancer by direct inspection. BMJ. 1992. 304, 534-535. [PubMed]
41.
Gupta, I., Sehgal, A. , Sehgal, R. and Ganguly, N. K. Vertical transmission of hepatitis B in north India. Journal of Hygiene, Epidemiology, Microbiology, and Immunology. 1992. 36, 263-267. [PubMed]
42.
Sehgal, A. , Singh, V., Bhambhani, S. and Luthra, U. K. Screening for cervical cancer by direct inspection. Lancet. 1991. 338, 282. [PubMed]
43.
Sehgal, A. , Singh, V., Bhambhani, S. and Luthra, U. K. Persistent uterine cervical dysplasia. Cancer. 1991. 67, 3165. [PubMed]
44.
Murthy, N. S., Juneja, A., Sehgal, A. , Prabhakar, A. K. and Luthra, U. K. Cancer projection by the turn of century-Indian science. Indian Journal of Cancer. 1990. 27, 74-82. [PubMed]
45.
Murthy, N. S., Sehgal, A. , Satyanarayana, L., Das, D. K., Singh, V., Das, B. C., Gupta, M. M., Mitra, A. B. and Luthra, U. K. Risk factors related to biological behaviour of precancerous lesions of the uterine cervix. British Journal of Cancer. 1990. 61, 732-736. [PubMed]
46.
Gupta, M. M., Parashari, A., Sehgal, A. and Luthra, U. K. Mutagenic cervical mucus in women with cervical intraepithelial neoplasia. Journal of the National Cancer Institute. 1990. 82, 234. [PubMed]
47.
Juneja, A., Murthy, N. S., Sehgal, A. , Prabhakar, A. K. and Luthra, U. K. Risk for development of cancer in three urban areas of India. Neoplasma. 1990. 37, 483-488. [PubMed]
48.
Das, B. C., Sehgal, A. , Murthy, N. S., Gopalkrishna, V., Sharma, J. K., Das, D. K., Singh, V. and Luthra, U. K. Human papillomavirus and cervical cancer in Indian women. Lancet. 1989. 2, 1271. [PubMed]
49.
Sehgal, A. , Murthy, N. S., Satyanarayana, L., Singh, V. and Luthra, U. K. Small family norm and uterine cervical cancer. Acta Obstetricia et Gynecologica Scandinavica. 1989. 68, 527-528. [PubMed]
50.
Saraya, A. K., Kumar, R. and Sehgal, A. K. Iron status in heterozygous beta-thalassemia: detection of coexisting iron deficiency by transferrin saturation and serum ferritin. Birth Defects Original Article Series. 1988. 23, 9-18. [PubMed]
51.
Sehgal, A. , Arankalle, V., Dhorje, S. P., Ramamoorthy, C. L., Phule, D. M. and Pavri, K. M. Diagnostic significance of anti-HBc-IgM in patients of acute viral hepatitis. The Indian Journal of Medical Research. 1986. 83, 547-549. [PubMed]
52.
Sreenivasan, M. A., Sehgal, A. , Prasad, S. R. and Dhorje, S. A sero-epidemiologic study of a water-borne epidemic of viral hepatitis in Kolhapur City, India. The Journal of Hygiene. 1984. 93, 113-122. [PubMed]
53.
Dhorje, S. P., Pavri, K. M., Prasad, S. R., Sehgal, A. and Phule, D. M. Horizontal transmission of hepatitis B virus infection in household contacts, Pune, India. Journal of Medical Virology. 1985. 16, 183-189. [PubMed]
54.
Sreenivasan, M. A., Arankalle, V. A., Sehgal, A. and Pavri, K. M. Non-A, non-B epidemic hepatitis: visualization of virus-like particles in the stool by immune electron microscopy. The Journal of General Virology. 1984. 65 ( Pt 5), 1005-1007. [PubMed]
55.
Sehgal, A. , David, G. F., Dubey, S. K. and Kumar, T. C. Patterns of transfer of tritiated progesterone into blood & cerebrospinal fluid of rhesus monkeys following diverse methods of administration. Indian Journal of Experimental Biology. 1980. 18, 707-708. [PubMed]
56.
Anand, K., Sehgal, A. , David, G. F., Bajaj, J. S. and Prasad, M. R. Effects of intranasal administration of hormonal steroids on serum testosterone and spermatogenesis in rhesus monkey (Macaca mulatta). Biology of Reproduction. 1980. 22, 935-940. [PubMed]
57.
Hoffmann, J. C. and Sehgal, A. Effects of exogenous administration of hormones on reproductive tract of the female Hawaiian mongoose Herpestes auropunctatus auropunctatus (Hodgson). Indian Journal of Experimental Biology. 1976. 14, 480-482. [PubMed]
Book Chapters:
Singh,V., Sehgal, A. , Parashari, A. Control of Cervical Cancer – A Manual for Visual Inspection of Cervix. Institute Of Cytology and Preventive Oncology (ICMR). 2002.
Sehgal, A. Penioscopy. In: Colposcopy, Singh, V. and Bhargava, V. L., B. I., Churchill Livingstone. 1994, pp 155-163.
Luthra, U. K., Mehta, S., Bhargava, N. C., Ramachandran, P., Murthy, N. S., Sehgal, A. and Saxena, B. N. Reproductive tract infections in India: the need for comprehensive health policy and programmes. In:Reproductive Tract Infections, Germain, A et al., Plenum Press. 1992. pp 317-342.
Grant Support:
Project Title Role Funding Agency Sanction Number Sanction Date
Comparative role of Genetic and environmental factors in the process of cervical carcinogenesis
Department of Science & Technology, Government of India
1998
My CV: Download
Type of Neoplasms
Female genital system
Cervix