Rituraj Konwar, Ph.D.
Scientist C
Central Drug Research Institute
Endocrinology Division
Lucknow - 226 001
Uttar Pradesh
E-mail: r_konwar@cdri.res.in
Phone: +91-522-2612411-18, Extn. 4306
URL: http://www.cdriindia.org/rituraj.htm
Area of Specialization:
Endocrinology
Research Summary:
Development of novel therapeutic molecules against breast cancer
Publications:
1.
Sashidhara, K. V., Rosaiah, J. N., Kumar, M., Gara, R. K., Nayak, L. V., Srivastava, K., Bid, H. K. and Konwar, R. Neo-tanshinlactone inspired synthesis, in vitro evaluation of novel substituted benzocoumarin derivatives as potent anti-breast cancer agents. Bioorganic & Medicinal Chemistry Letters. 2010. 20, 7127-7131. [PubMed]
2.
Konwar, R. , Manchanda, P. K., Chaudhary, P., Nayak, V. L., Singh, V. and Bid, H. K. Glutathione S-transferase gene variants and risk of benign prostate hyperplasia in a North Indian population. Asian Pacific Journal of Cancer Prevention : APJCP. 2010. 11, 365-370. [PubMed]
3.
Sharma, A., Chakravarti, B., Gupt, M. P., Siddiqui, J. A., Konwar, R. and Tripathi, R. P. Synthesis and anti breast cancer activity of biphenyl based chalcones. Bioorganic & Medicinal Chemistry. 2010. [PubMed]
4.
Gupta, U., Dwivedi, S. K., Bid, H. K., Konwar, R. and Jain, N. K. Ligand anchored dendrimers based nanoconstructs for effective targeting to cancer cells. International Journal of Pharmaceutics. 2010. 393, 185-196. [PubMed]
5.
Samanta, K., Chakravarti, B., Mishra, J. K., Dwivedi, S. K., Nayak, L. V., Choudhry, P., Bid, H. K., Konwar, R. , Chattopadhyay, N. and Panda, G. Anti-tumor activity of a new series of benzoxazepine derivatives in breast cancer. Bioorganic & Medicinal Chemistry Letters. 2010. 20, 283-287. [PubMed]
6.
Hanif, K., Bid, H. K. and Konwar, R. Reinventing the ACE inhibitors: some old and new implications of ACE inhibition. Hypertension Research. 2010. 33, 11-21. [PubMed]
7.
Kumar, S., Deshpande, S., Chandra, V., Kitchlu, S., Dwivedi, A., Nayak, V. L., Konwar, R. , Prabhakar, Y. S. and Sahu, D. P. Synthesis and biological evaluation of 2,3,4-triarylbenzopyran derivatives as SERM and therapeutic agent for breast cancer. Bioorganic & Medicinal Chemistry. 2009. 17, 6832-6840. [PubMed]
8.
Bid, H. K., Konwar, R. , Aggarwal, C. G., Gautam, S., Saxena, M., Nayak, V. L. and Banerjee, M. Vitamin D receptor (FokI, BsmI and TaqI) gene polymorphisms and type 2 diabetes mellitus: a North Indian study. Indian Journal of Medical Sciences. 2009. 63, 187-194. [PubMed]
9.
Reddy, K. P., Bid, H. K., Nayak, V. L., Chaudhary, P., Chaturvedi, J. P., Arya, K. R., Konwar, R. and Narender, T. In vitro and in vivo anticancer activity of 2-deacetoxytaxinine J and synthesis of novel taxoids and their in vitro anticancer activity. European Journal of Medicinal Chemistry. 2009. 44, 3947-3953. [PubMed]
10.
Shankar, R., Chakravarti, B., Singh, U. S., Ansari, M. I., Deshpande, S., Dwivedi, S. K., Bid, H. K., Konwar, R. , Kharkwal, G., Chandra, V., Dwivedi, A. and Hajela, K. Synthesis and biological evaluation of 3,4,6-triaryl-2-pyranones as a potential new class of anti-breast cancer agents. Bioorganic & Medicinal Chemistry. 2009. 17, 3847-3856. [PubMed]
11.
Bid, H. K., Konwar, R. and Singh, V. Benign prostatic hyperplasia: is it a growing public health concern for India? Indian Journal of Medical Sciences. 2008. 62, 373-374. [PubMed]
12.
Bid, H. K., Konwar, R. , Agrawal, C. G. and Banerjee, M. Association of IL-4 and IL-1RN (receptor antagonist) gene variants and the risk of type 2 diabetes mellitus: a study in the north Indian population. Indian Journal of Medical Sciences. 2008. 62, 259-266. [PubMed]
13.
Konwar, R. , Chattopadhyay, N. and Bid, H. K. Genetic polymorphism and pathogenesis of benign prostatic hyperplasia. BJU International. 2008. 102, 536-544. [PubMed]
14.
Konwar, R. , Chaudhary, P., Kumar, S., Mishra, D., Chattopadhyay, N. and Bid, H. K. Breast cancer risk associated with polymorphisms of IL-1RN and IL-4 gene in Indian women. Oncology Research. 2009. 17, 367-372. [PubMed]
15.
Konwar, R. , Gara, R., Singh, M., Singh, V., Chattopadhyay, N. and Bid, H. K. Association of interleukin-4 and interleukin-1 receptor antagonist gene polymorphisms and risk of benign prostatic hyperplasia. Urology. 2008. 71, 868-872. [PubMed]
16.
Sashidhara, K. V., Rosaiah, J. N., Kumar, A., Bid, H. K., Konwar, R. and Chattopadhyay, N. Cell growth inhibitory action of an unusual labdane diterpene, 13-epi-sclareol in breast and uterine cancers in vitro. Phytotherapy Research : PTR. 2007. 21, 1105-1108. [PubMed]
Education
::
Ph.D.
Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh
Type of Neoplasms
Breast
Female