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Rituraj Konwar, Ph.D.
Scientist C 
Central Drug Research Institute
Endocrinology Division
Lucknow - 226 001   
Uttar Pradesh   
Phone: +91-522-2612411-18, Extn. 4306
Area of Specialization:
Research Summary:
Development of novel therapeutic molecules against breast cancer
1. Sashidhara, K. V., Rosaiah, J. N., Kumar, M., Gara, R. K., Nayak, L. V., Srivastava, K., Bid, H. K. and Konwar, R.  Neo-tanshinlactone inspired synthesis, in vitro evaluation of novel substituted benzocoumarin derivatives as potent anti-breast cancer agents. Bioorganic & Medicinal Chemistry Letters. 2010.  20, 7127-7131. [PubMed]
2. Konwar, R., Manchanda, P. K., Chaudhary, P., Nayak, V. L., Singh, V. and Bid, H. K.  Glutathione S-transferase gene variants and risk of benign prostate hyperplasia in a North Indian population. Asian Pacific Journal of Cancer Prevention : APJCP. 2010.  11, 365-370. [PubMed]
3. Sharma, A., Chakravarti, B., Gupt, M. P., Siddiqui, J. A., Konwar, R. and Tripathi, R. P.  Synthesis and anti breast cancer activity of biphenyl based chalcones. Bioorganic & Medicinal Chemistry. 2010.  [PubMed]
4. Gupta, U., Dwivedi, S. K., Bid, H. K., Konwar, R. and Jain, N. K.  Ligand anchored dendrimers based nanoconstructs for effective targeting to cancer cells. International Journal of Pharmaceutics. 2010.  393, 185-196. [PubMed]
5. Samanta, K., Chakravarti, B., Mishra, J. K., Dwivedi, S. K., Nayak, L. V., Choudhry, P., Bid, H. K., Konwar, R., Chattopadhyay, N. and Panda, G.  Anti-tumor activity of a new series of benzoxazepine derivatives in breast cancer. Bioorganic & Medicinal Chemistry Letters. 2010.  20, 283-287. [PubMed]
6. Hanif, K., Bid, H. K. and Konwar, R.  Reinventing the ACE inhibitors: some old and new implications of ACE inhibition. Hypertension Research. 2010.  33, 11-21. [PubMed]
7. Kumar, S., Deshpande, S., Chandra, V., Kitchlu, S., Dwivedi, A., Nayak, V. L., Konwar, R., Prabhakar, Y. S. and Sahu, D. P.  Synthesis and biological evaluation of 2,3,4-triarylbenzopyran derivatives as SERM and therapeutic agent for breast cancer. Bioorganic & Medicinal Chemistry. 2009.  17, 6832-6840. [PubMed]
8. Bid, H. K., Konwar, R., Aggarwal, C. G., Gautam, S., Saxena, M., Nayak, V. L. and Banerjee, M.  Vitamin D receptor (FokI, BsmI and TaqI) gene polymorphisms and type 2 diabetes mellitus: a North Indian study. Indian Journal of Medical Sciences. 2009.  63, 187-194. [PubMed]
9. Reddy, K. P., Bid, H. K., Nayak, V. L., Chaudhary, P., Chaturvedi, J. P., Arya, K. R., Konwar, R. and Narender, T.  In vitro and in vivo anticancer activity of 2-deacetoxytaxinine J and synthesis of novel taxoids and their in vitro anticancer activity. European Journal of Medicinal Chemistry. 2009.  44, 3947-3953. [PubMed]
10. Shankar, R., Chakravarti, B., Singh, U. S., Ansari, M. I., Deshpande, S., Dwivedi, S. K., Bid, H. K., Konwar, R., Kharkwal, G., Chandra, V., Dwivedi, A. and Hajela, K.  Synthesis and biological evaluation of 3,4,6-triaryl-2-pyranones as a potential new class of anti-breast cancer agents. Bioorganic & Medicinal Chemistry. 2009.  17, 3847-3856. [PubMed]
11. Bid, H. K., Konwar, R. and Singh, V.  Benign prostatic hyperplasia: is it a growing public health concern for India? Indian Journal of Medical Sciences. 2008.  62, 373-374. [PubMed]
12. Bid, H. K., Konwar, R., Agrawal, C. G. and Banerjee, M.  Association of IL-4 and IL-1RN (receptor antagonist) gene variants and the risk of type 2 diabetes mellitus: a study in the north Indian population. Indian Journal of Medical Sciences. 2008.  62, 259-266. [PubMed]
13. Konwar, R., Chattopadhyay, N. and Bid, H. K.  Genetic polymorphism and pathogenesis of benign prostatic hyperplasia. BJU International. 2008.  102, 536-544. [PubMed]
14. Konwar, R., Chaudhary, P., Kumar, S., Mishra, D., Chattopadhyay, N. and Bid, H. K.  Breast cancer risk associated with polymorphisms of IL-1RN and IL-4 gene in Indian women. Oncology Research. 2009.  17, 367-372. [PubMed]
15. Konwar, R., Gara, R., Singh, M., Singh, V., Chattopadhyay, N. and Bid, H. K.  Association of interleukin-4 and interleukin-1 receptor antagonist gene polymorphisms and risk of benign prostatic hyperplasia. Urology. 2008.  71, 868-872. [PubMed]
16. Sashidhara, K. V., Rosaiah, J. N., Kumar, A., Bid, H. K., Konwar, R. and Chattopadhyay, N.  Cell growth inhibitory action of an unusual labdane diterpene, 13-epi-sclareol in breast and uterine cancers in vitro. Phytotherapy Research : PTR. 2007.  21, 1105-1108. [PubMed]


Ph.D. Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh
Type of Neoplasms
  Last modified on : Mar 4, 2011
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