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Arun Kumar Trivedi, Ph.D.
Scientist C 
Central Drug Research Institute
DTDD Division
Lucknow - 226 001   
Uttar Pradesh   
Positions Held:
Position Affiliation Time Period
Scientist C Central Drug Research Institute, Lucknow, India Present
Area of Specialization:
Molecular Oncology
Research Summary:
Molecular biology of acute myeloid leukemia and role of C/EBPalpha in leukemogenesis
Molecular biology and pathogenesis of breast cancer: mechanism of action of anti-cancer drugs and compounds using mass spectrometry based proteomics approach
1. Bararia, D., Trivedi, A. K., Zada, A. A., Greif, P. A., Mulaw, M. A., Christopeit, M., Hiddemann, W., Bohlander, S. K. and Behre, G.  Proteomic identification of the MYST domain histone acetyltransferase TIP60 (HTATIP) as a co-activator of the myeloid transcription factor C/EBPalpha. Leukemia 2008.  22, 800-807. [PubMed]
2. Trivedi, A. K., Pal, P., Behre, G. and Singh, S. M.  Multiple ways of C/EBPalpha inhibition in myeloid leukaemia. European Journal of Cancer. 2008.  44, 1516-1523. [PubMed]
3. Singh, S. M., Trivedi, A. K. and Behre, G.  C/EBPalpha S248A mutation reduces granulocytic differentiation in human leukemic K562 cells. Biochemical and Biophysical Research Communications. 2008.  369, 692-694. [PubMed]
4. Geletu, M., Balkhi, M. Y., Peer, Z., Christopeit, M., Pulikkan, J. A., Trivedi, A. K., Tenen, D. G. and Behre, G.  Target proteins of C/EBPalphap30 in AML: C/EBPalphap30 enhances sumoylation of C/EBPalphap42 via up-regulation of Ubc9. Blood. 2007.  110, 3301-3309. [PubMed]
5. Trivedi, A. K., Bararia, D., Christopeit, M., Peerzada, A. A., Singh, S. M., Kieser, A., Hiddemann, W., Behre, H. M. and Behre, G.  Proteomic identification of C/EBP-DBD multiprotein complex: JNK1 activates stem cell regulator C/EBPalpha by inhibiting its ubiquitination. Oncogene. 2007.  26, 1789-1801. [PubMed]
6. Balkhi, M. Y., Trivedi, A. K., Geletu, M., Christopeit, M., Bohlander, S. K., Behre, H. M. and Behre, G.  Proteomics of acute myeloid leukaemia: Cytogenetic risk groups differ specifically in their proteome, interactome and post-translational protein modifications. Oncogene. 2006.  25, 7041-7058. [PubMed]
7. Zada, A. A., Pulikkan, J. A., Bararia, D., Geletu, M., Trivedi, A. K., Balkhi, M. Y., Hiddemann, W. D., Tenen, D. G., Behre, H. M. and Behre, G.  Proteomic discovery of Max as a novel interacting partner of C/EBPalpha: a Myc/Max/Mad link. Leukemia 2006.  20, 2137-2146. [PubMed]


M.Sc. Banaras Hindu University, Varanasi, Uttar Pradesh, India
Ph.D. Ludwig Maximilians University, Munich, Germany
  Last modified on : Mar 4, 2011
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