Arun Kumar Trivedi,                               Ph.D. 
                               
                              Scientist C  
                           
                         
                                  
         
                                                    
                                                    
                            Central Drug Research Institute 
                           
                                                                              
                            DTDD Division  
                           
                                                                              
                            Lucknow - 226 001                                 
                           
                                                    
                            Uttar Pradesh                                 
                           						  
                                                            
                           
                                                    
                            E-mail: arun3vedi@cdri.res.in 
                           
                                                    
                               
                           
                          
                            URL:   http://www.cdriindia.org/aruntrivedi.htm  
                           
                          
                          						  
                              
                           
						  
	                             
                            Positions Held:  
                           
                                                    
                            
                                
                                  Position  
                                  Affiliation  
                                  Time Period   
                                 
                                                                
                                  Scientist C  
                                  Central Drug Research Institute, Lucknow, India 
                                  
								  Present 
                                 
                                                            
 
                           
                          
                              
                           
                                                                              
                            Area of Specialization:  
                           
                          
                          
                          
  
     
    Molecular Oncology 
   
    
                          
                        
                           
                           
                         
                         
                                                    
                                                    
                          
                             
                           
                                                    
                             Research Summary:  
                           
                                                    
                            
                                                                
                                   
                                  Molecular biology of acute myeloid leukemia and role of C/EBPalpha in leukemogenesis 
                                 
                                                                
                                   
                                  Molecular biology and pathogenesis of breast cancer: mechanism of action of anti-cancer drugs and compounds using mass spectrometry based proteomics approach 
                                 
                                                            
 
                           
                          
                              
                           
                                                    
                            Publications:  
                           
                          
                            
	
		
			
				1. 
			
				Bararia, D., Trivedi, A. K. , Zada, A. A., Greif, P. A., Mulaw, M. A., Christopeit, M., Hiddemann, W., Bohlander, S. K. and Behre, G.  Proteomic identification of the MYST domain histone acetyltransferase TIP60 (HTATIP) as a co-activator of the myeloid transcription factor C/EBPalpha. Leukemia  2008.  22, 800-807. [PubMed]  
		 
		
			
				2. 
			
				Trivedi, A. K. , Pal, P., Behre, G. and Singh, S. M.  Multiple ways of C/EBPalpha inhibition in myeloid leukaemia. European Journal of Cancer.  2008.  44, 1516-1523. [PubMed]  
		 
		
			
				3. 
			
				Singh, S. M., Trivedi, A. K.  and Behre, G.  C/EBPalpha S248A mutation reduces granulocytic differentiation in human leukemic K562 cells. Biochemical and Biophysical Research Communications.  2008.  369, 692-694. [PubMed]  
		 
		
			
				4. 
			
				Geletu, M., Balkhi, M. Y., Peer, Z., Christopeit, M., Pulikkan, J. A., Trivedi, A. K. , Tenen, D. G. and Behre, G.  Target proteins of C/EBPalphap30 in AML: C/EBPalphap30 enhances sumoylation of C/EBPalphap42 via up-regulation of Ubc9. Blood.  2007.  110, 3301-3309. [PubMed]  
		 
		
			
				5. 
			
				Trivedi, A. K. , Bararia, D., Christopeit, M., Peerzada, A. A., Singh, S. M., Kieser, A., Hiddemann, W., Behre, H. M. and Behre, G.  Proteomic identification of C/EBP-DBD multiprotein complex: JNK1 activates stem cell regulator C/EBPalpha by inhibiting its ubiquitination. Oncogene.  2007.  26, 1789-1801. [PubMed]  
		 
		
			
				6. 
			
				Balkhi, M. Y., Trivedi, A. K. , Geletu, M., Christopeit, M., Bohlander, S. K., Behre, H. M. and Behre, G.  Proteomics of acute myeloid leukaemia: Cytogenetic risk groups differ specifically in their proteome, interactome and post-translational protein modifications. Oncogene.  2006.  25, 7041-7058. [PubMed]  
		 
		
			
				7. 
			
				Zada, A. A., Pulikkan, J. A., Bararia, D., Geletu, M., Trivedi, A. K. , Balkhi, M. Y., Hiddemann, W. D., Tenen, D. G., Behre, H. M. and Behre, G.  Proteomic discovery of Max as a novel interacting partner of C/EBPalpha: a Myc/Max/Mad link. Leukemia  2006.  20, 2137-2146. [PubMed]  
		 
	 
	 
  
                           
                         
                                                
 
                      
                          
                            
                                                                 
                                   
                             
                            
                                
                             
                            
                              
                                  
                                     
                                   
                                  
                                                                            
                                        
                                                                                    
                                            Education  
 
                                           
                                                                                    
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                                            M.Sc.                                                    				
				 
                                                    Banaras Hindu University, Varanasi, Uttar Pradesh, India                                                                        
 
                                           
                                                                                    
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                                            Ph.D.                                                    				
				 
                                                    Ludwig Maximilians University, Munich, Germany