Sanjeeva Srivastava, Ph.D.
Associate Professor
Indian Institute of Technology
Department of Biosciences and Bioengineering
Powai
Mumbai - 400 076
Maharashtra
E-mail: sanjeeva@iitb.ac.in
Phone: +91-22-25767779
Fax: +91-22-25723480
URL: http://www.bio.iitb.ac.in/people/faculty/srivastava-s
Positions Held:
Position
Affiliation
Time Period
Assistant Professor
Indian Institute of Technology Bombay, Mumbai, India
2009-Present
Post Doctoral Fellowship
Harvard Institute of Proteomics, Harvard Medical School, USA
2007-2009
Area of Specialization:
Proteomics
Research Summary:
Proteomic analysis of human gliomas for biomarker discovery
Malaria biomarker discovery using proteomics
JAK-STAT interactome and cancer
Understanding regulation of Z-ring assembly and identification of drug targets
Publications:
1. Ray, S., Kamath, K. S., Srivastava, R., Raghu, D., Gollapalli, K., Jain, R., Gupta, S. V., Ray, S., Taur, S., Dhali, S., Gogtay, N., Thatte, U., Srikanth, R., Patankar, S. and Srivastava, S. Serum proteome analysis of vivax malaria: An insight into the disease pathogenesis and host immune response. Journal of Proteomics. 2012. 75, 3063-3080. [PubMed] 2. Gollapalli, K., Ray, S., Srivastava, R., Renu, D., Singh, P., Dhali, S., Bajpai, D., Srikanth, R., Moiyadi, A. and Srivastava, S. Investigation of serum proteome alterations in human glioblastoma multiforme. Proteomics. 2012. 12, 2378-2390. [PubMed] 3. Ray, S., Renu, D., Srivastava, R., Gollapalli, K., Taur, S., Jhaveri, T., Dhali, S., Chennareddy, S., Potla, A., Dikshit, J. B., Srikanth, R., Gogtay, N., Thatte, U., Patankar, S. and Srivastava, S. Proteomic investigation of falciparum and vivax malaria for identification of surrogate protein markers. PloS One. 2012. 7, e41751. [PubMed] 4. Ray, S., Koshy, N. R., Diwakar, S., Nair, B. and Srivastava, S. Sakshat Labs: India's virtual proteomics initiative. PLoS Biology. 2012. 10, e1001353. [PubMed] 5. Srivastava, R., Ray, S., Vaibhav, V., Gollapalli, K., Jhaveri, T., Taur, S., Dhali, S., Gogtay, N., Thatte, U., Srikanth, R. and Srivastava, S. Serum profiling of leptospirosis patients to investigate proteomic alterations. Journal of Proteomics. 2012. 76 Spec No., 56-68. [PubMed] 6. Ray, S., Moiyadi, A. and Srivastava, S. Epidemiology: Biorepositories for cancer research in developing countries. Nature Reviews. Clinical Oncology. 2013. 10, 434-436. [PubMed] 7. Srivastava, S., Ozdemir, V., Ray, S., Panga, J. R., Noronha, S., Nair, B. and Diwakar, S. Online education: E-learning booster in developing world. Nature. 2013. 501, 316. [PubMed]
1.
Chatterji, B. P., Jindal, B., Srivastava, S. and Panda, D. Microtubules as antifungal and antiparasitic drug targets. Expert Opinion On Therapeutic Patents. 2011. 21, 167-186. [PubMed]
1.
Ray, S., Chandra, H. and Srivastava, S. Nanotechniques in proteomics: current status, promises and challenges. Biosensors & Bioelectronics. 2010. 25, 2389-2401. [PubMed]
2.
Chandra, H. and Srivastava, S. Cell-free synthesis-based protein microarrays and their applications. Proteomics. 2010. 10, 717-730. [PubMed]
3.
Ray, S., Mehta, G. and Srivastava, S. Label-free detection techniques for protein microarrays: prospects, merits and challenges. Proteomics. 2010. 10, 731-748. [PubMed]
4.
Srivastava, S. and LaBaer, J. Nanotubes light up protein arrays. Nature Biotechnology. 2008. 26, 1244-1246. [PubMed]
5.
Ramachandran, N., Srivastava, S. and Labaer, J. Applications of protein microarrays for biomarker discovery. Proteomics. Clinical Applications. 2008. 2, 1444-1459. [PubMed]
6.
Krishnaswamy, S. S., Srivastava, S. , Mohammadi, M., Rahman, M. H., Deyholos, M. K. and Kav, N. N. Transcriptional profiling of pea ABR17 mediated changes in gene expression in Arabidopsis thaliana. BMC Plant Biology. 2008. 8, 91. [PubMed]
7.
Liang, Y., Srivastava, S. , Rahman, M. H., Strelkov, S. E. and Kav, N. N. Proteome changes in leaves of Brassica napus L. as a result of Sclerotinia sclerotiorum challenge. Journal of Agricultural and Food Chemistry. 2008. 56, 1963-1976. [PubMed]
8.
Srivastava, S. , Rahman, M. H., Shah, S. and Kav, N. N. Constitutive expression of the pea ABA-responsive 17 (ABR17) cDNA confers multiple stress tolerance in Arabidopsis thaliana. Plant Biotechnology Journal. 2006. 4, 529-549. [PubMed]
9.
Jain, S., Srivastava, S. , Sarin, N. B. and Kav, N. N. Proteomics reveals elevated levels of PR 10 proteins in saline-tolerant peanut (Arachis hypogaea) calli. Plant Physiology and Biochemistry : Societe Francaise De Physiologie Vegetale. 2006. 44, 253-259. [PubMed]
10.
Srivastava, S. , Fristensky, B. and Kav, N. N. Constitutive expression of a PR10 protein enhances the germination of Brassica napus under saline conditions. Plant & Cell Physiology. 2004. 45, 1320-1324. [PubMed]
11.
Cao, T., Srivastava, S. , Rahman, M.H., Kav, N.N.V., Hotte, N., Deyholos, M.K. and Strelkov, S.E. Proteomic changes in the roots of Brassica napus in response to infection by Plasmodiophora brassicae. Plant Science . 2004 174, 97–115.
12.
Srivastava, S. , Rahman, H., Emery, R.J.N., and Kav, N.N.V. A crucial role for cytokinins in pea ABR17-mediated enhanced germination and early seedling growth of Arabidopsis thaliana under saline and low temperature stresses. Journal of Plant Growth Regulation . 2007. 26, 26–37
13.
Yang, B., Srivastava, S. , Deyholos, M.K. and Kav, N.N.V. Transcriptional profiling of canola (Brassica napus L.) responses to the fungal pathogen Sclerotinia sclerotiorum. Plant Science . 2007. 173, 156-171.
14.
Dunfield, K., Srivastava, S. , Shah, S. and Kav, N.N.V. Constitutive expression of ABR17 cDNA enhances germination and promotes early flowering in Brasscia napus. Plant Science . 2007. 173, 521-532.
15
Kav N.N.V., Srivastava S. , Yajima W. and Sharma N. Application of proteomics to investigate plant-microbe interactions. Current Proteomics. 2007. 4, 28-43.
16.
Srivastava, S. , Emery, R.J.N., Kurepin, L.V., Reid, D.M., Fristensky, B. and Kav, N.N.V. Pea PR 10.1 is a ribonuclease and its transgenic expression elevates cytokinin levels. Plant Growth Regulation . 2006. 49, 17-25.
17.
Srivastava, S. , Fristensky, B. and Kav, N.N.V. Constitutive expression of a PR 10 protein enhances the germination of Brassica napus under saline conditions. Plant and Cell Physiology. 2004. 45, 1320-1324.
18.
Kav, N.N.V., Srivastava, S. , Goonewardene, L. and Blade, S. Proteome-level changes in the roots of Pisum sativum L. in response to salinity. Annals of Applied Biology . 2004. 145, 217-230.
Book Chapters:
Spera R., Badino F., Hainsworth, G., Fuentes, M., Srivastava, S. , LaBaer, J. and Nicolini, C. (2010) “Label free detection of NAPPA: III. Mass spectrometry”. In: The Proteome: Technologies and Applications. Pan Stanford Series on Nanobiotechnology - Volume 3 (Eds: Josh LaBaer and Claudio Nicolini) In press
Kav N.N.V., Srivastava S. , Yajima W. and Ali S. 2008. Proteomics in developing countries. In: Plant proteomics: Technologies, strategies, and applications (Eds: Ganesh K. Agrawal and Randeep Rakwal), Wiley-Interscience, USA 570-581.
Kav N.V.V., Yajima W., Sharma N., Srivastava S. and Krishnaswamy, S. (2007) Crop Improvement (The Gene Revolution), in Animal and Plant Productivity, (Ed: Robert J. Hudson), in Encyclopedia of Life Support Systems (EOLSS), Developed under the Auspices of the UNESCO, Eolss Publishers, Oxford, UK.
Srivastava S. , Ali S. and Kav N.N.V. 2005. An overview on proteomics. In: Biotechnology in the welfare of mankind (Eds: I. A. Khan and A. Khanum), volume II, Ukaaz Publications, Hyderabad, India 179-253.
Grant Support:
Project Title
Role
Funding Agency
Sanction Number
Sanction Date
Proteomic analysis of human gliomas for biomarker discovery
Department of Biotechnology, Government of India
2010
Virtual Proteomics Laboratory
Ministry of Human Resources and Development, Government of India
2010
Serum profiling of P. falciparum malaria patients by using proteomic techniques
Bhabha Atomic Research Centre, Department of Atomic Energy, Government of India
Understanding regulation of Z-ring assembly and identification of drug targets
Bhabha Atomic Research Centre, Department of Atomic Energy, Government of India
Understanding protein-protein interactions of JAK-STAT pathway proteins
Department of Science & Technology, Government of India
2010
OSCAR for Proteomics and Cellular and Molecular Biology
Ministry of Human Resources and Development, Government of India
2010
Proteomics Informatics System
Apple Research & Technology Support, UK
2009
Education
::
Ph.D.
University of Alberta, Canada
Honors and Awards
::
June 2010, Virtual Lab Project, Ministry of Human Resources and Development
::
May 2010, Department of Biotechnology Grant
::
April 2010, Young Scientist Award DAE-BRNS
::
March 2010, DST-SERC Fast Track for Young Scientists
::
March 2010, OSCAR Animation Project, Ministry of Human Resources and Development
::
May 2009, Apple Research Technology Support award, UK
::
March 2009, Young Faculty Award IIT Bombay
::
2005, Robert Simonet Graduate Award, Canada
::
2005, National Young Scientist Award, Canada
::
April 2012, IIT Bombay Young Investigator of the Year 2011
::
May 2012, Guest professorship – Central South University, China
Member
::
Harvard Medical School Nominee for Science Memberships