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Manisha R. Madkaikar, M.D.
Scientist D 
National Institute of Immunohaematology
Department of Paediatric Immunology and Leukemia Biology
13th floor, New Multistoreyed Building, KEM Hospital Campus, Parel
Mumbai - 400 012   
Phone: +91-22-24138518, 24138519, 24111161
Fax: +91-22-24138521
Area of Specialization:
Molecular Biology
Research Summary:
Haematopoietic stem cells and hematological malignancies
Primary immunodeficiency disorders
1. Madkaikar, M., Gupta, M., Jijina, F. and Ghosh, K.  Paroxysmal nocturnal haemoglobinuria: diagnostic tests, advantages, & limitations. European Journal of Haematology. 2009.  83, 503-511. [PubMed]
2. Swaminathan, S., Madkaikar, M., Ghosh, K., Vundinti, B. R., Kerketta, L. and Gupta, M.  Novel immunophenotypic and morphologic presentation in acute myeloid leukemia (AML) with JAK2 V617F mutation. European Journal of Haematology. 2010.  84, 180-182. [PubMed]
3. Shmukler, B. E., Kedar, P. S., Warang, P., Desai, M., Madkaikar, M., Ghosh, K., Colah, R. B. and Alper, S. L.  Hemolytic anemia and distal renal tubular acidosis in two Indian patients homozygous for SLC4A1/AE1 mutation A858D. American Journal of Hematology. 2010.  85, 824-828. [PubMed]
4. Pereira, W. C., Khushnooma, I., Madkaikar, M. and Ghosh, K.  Reproducible methodology for the isolation of mesenchymal stem cells from human umbilical cord and its potential for cardiomyocyte generation. Journal of Tissue Engineering and Regenerative Medicine. 2008.  2, 394-399. [PubMed]
5. Vundinti, B. R., Kerketta, L., Madkaikar, M., Jijina, F. and Ghosh, K.  Three way translocation in a new variant of t(8;21) acute myeloid leukemia involving Xp22. Indian Journal of Cancer. 2008.  45, 30-32. [PubMed]
6. Meera, V., Jijina, F., Shrikande, M., Madkaikar, M. and Ghosh, K.  Twin pregnancy in a patient of chronic myeloid leukemia on imatinib therapy. Leukemia Research. 2008.  32, 1620-1622. [PubMed]
7. Ghosh, K., Madkaikar, M. and Jijina, F.  Spontaneous resolution of severe aplastic anemia following thymic hemorrhage. Acta Haematologica. 2008.  119, 69-72. [PubMed]
8. Madkaikar, M., Gupta, M., Ghosh, K., Swaminathan, S., Sonawane, L. and Mohanty, D.  Optimising methods of red cell sedimentation from cord blood to maximise nucleated cell recovery prior to cryopreservation. British Journal of Biomedical Science. 2007.  64, 157-159. [PubMed]
9. Madkaikar, M., Ghosh, K., Gupta, M., Swaminathan, S. and Mohanty, D.  Ex vivo expansion of umbilical cord blood stem cells using different combinations of cytokines and stromal cells. Acta Haematologica. 2007.  118, 153-159. [PubMed]
10. Ghosh, K., Madkaikar, M., Jijina, F. and Shetty, S.  Fractures of long bones in severe haemophilia. Haemophilia . 2007.  13, 337-339. [PubMed]
11. Nair, A. P., Jijina, F., Ghosh, K., Madkaikar, M., Shrikhande, M. and Nema, M.  Osteoporosis in young haemophiliacs from western India. American Journal of Hematology. 2007.  82, 453-457. [PubMed]
12. Babu, R. a. o., Kerketta, L., Madkaikar, M., Farah, J. and Ghosh, K.  Hybrid cytogenetics of chronic lymphocytic leukemia and follicular cell lymphoma in a case of non-Hodgkin's lymphoma. Acta Haematologica. 2006.  116, 150-152. [PubMed]
13. Ghosh, K., Nair, A. P., Jijina, F., Madkaikar, M., Shetty, S. and Mohanty, D.  Intracranial haemorrhage in severe haemophilia: prevalence and outcome in a developing country. Haemophilia : the Official Journal of the World Federation of Hemophilia. 2005.  11, 459-462. [PubMed]
14. Kedar, P. S., Nadkarni, A. H., Phanasgoankar, S., Madkaikar, M., Ghosh, K., Gorakshakar, A. C., Colah, R. B. and Mohanty, D.  Congenital methemoglobinemia caused by Hb-MRatnagiri (beta-63CAT-->TAT, His-->Tyr) in an Indian family. American Journal of Hematology. 2005.  79, 168-170. [PubMed]
15. Madkaikar, M. and Ghosh, K.  Immunotherapy in benzene-induced aplastic anemia using a biotherapeutic approach--is it durable? Stem Cells and Development. 2004.  13, 161-163. [PubMed]
16. Madkaikar, M. and Ghosh, K.  Treating patients of myelodysplastic syndrome with antithymocytic globulin--should we be more selective? Blood. 2003.  102, 3851-3853. [PubMed]
17. Ghosh, K., Vundinti, B. R., Kerketta, L., Madkaikar, M., Mohanty, D. and Jijina, F.  Severe megakaryocytic dysplasia in a case of myelodysplasia progressing to acute megakaryocytic leukemia presenting with dic(1;16)(q21;p13.3) and t(1;22)(p13;q13). Cancer Genetics and Cytogenetics. 2003.  146, 176-178. [PubMed]
18. Ghosh, K., Iyer, Y., Basu, A., Madkaikar, M., Jijina, F., Shankarkumar, U. and Mohanty, D.  Virological, serological and haemopoietic colony studies and its correlation with the outcome of severe aplastic anemia. The Hematology Journal. 2003.  4, 292-294. [PubMed]
19. Vundinti, B. R., Madkaikar, M., Kerketta, L., Jijina, F., Ghosh, K., Mohanty, D. and Jijina, F.  A novel translocation der(4)t(1;4)(q21;q35) and a marker chromosome in a case of myelodysplastic syndrome. Cancer Genetics and Cytogenetics. 2003.  144, 175-176. [PubMed]
20. Ghosh, K., Madkaikar, M., Jijina, F., Gandhi, S., Shetty, S. and Mohanty, D.  Open heart surgery with mitral valve replacement--ordeal of an undiagnosed haemophilia patient. Clinical and Laboratory Haematology. 2003.  25, 131-133. [PubMed]
21. Ghosh, K., Jijina, F., Shetty, S., Madkaikar, M. and Mohanty, D.  First-time development of FVIII inhibitor in haemophilia patients during the postoperative period. Haemophilia : the Official Journal of the World Federation of Hemophilia. 2002.  8, 776-780. [PubMed]
22. Madkaikar, M., Ghosh, K., Jijina, F., Gupta, M., Rajpurkar, M. and Mohanty, D.  Tuberculosis and immune thrombocytopenia. Haematologica. 2002.  87, ELT38. [PubMed]
23. Ghosh, K., Gosavi, S., Pathare, A., Madkaikar, M., Rao, V. B. and Mohanty, D.  Low cost autologous peripheral blood stem cell transplantation performed in a municipal hospital for a patient with plasma cell leukaemia. Clinical and Laboratory Haematology. 2002.  24, 187-190. [PubMed]
24. Ghosh, K., Madkaikar, M., Iyer, Y., Pathare, A., Jijina, F. and Mohanty, D.  Systemic capillary leak syndrome preceding plasma cell leukaemia. Acta Haematologica. 2001.  106, 118-121. [PubMed]
25. Jijina, F., Ghosh, K., Madkaikar, M. and Mohanty, D.  Ophthalmic surgery in haemophilia. Haemophilia. 2001.  7, 464-467. [PubMed]
26. Ghosh, K., Shetty, S., Madkaikar, M., Pawar, A., Nair, S., Khare, A., Pathare, A., Jijina, F. and Mohanty, D.  Venous thromboembolism in young patients from western India: a study. Clinical and Applied Thrombosis/hemostasis. 2001.  7, 158-165. [PubMed]
27. Ghosh, K., Joshi, S. H., Shetty, S., Pawar, A., Chipkar, S., Pujari, V., Madkaikar, M., Pathare, A. V., Jijina, F. and Mohanty, D.  Transfusion transmitted diseases in haemophilics from western India. The Indian Journal of Medical Research. 2000.  112, 61-64. [PubMed]
28. Shetty, S., Madkaikar, M., Nair, S., Pawar, A., Baindur, S., Pathare, A., Ghosh, K. and Mohanty, D.  Combined factor V and VIII deficiency in Indian population. Haemophilia. 2000.  6, 504-507. [PubMed]


M.D. in Medicine, Seth G. S. Medical College,Mumbai, 1994-1997
Honors and Awards
2005-2006, Awarded Associateship for specialized training of young scientists in niche areas of biotechnology by Department of Biotechnology
2009 - Best paper award for paper on ‘Clinical spectrum of Leukocyte Adhesion Deficiency-I from India and antenatal diagnosis for LAD-I for the first time in India.’ Presented at Mumbai Haematology group annual conference held at Tata Memorial Hospital, Mumbai
Dr. N.C. Kelkar award for standing first in M.D. (General Medicine) examination from Seth G.S. Medical College, Mumbai
  Last modified on : Mar 4, 2011
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