T. S. Sridhar,                               M.B.B.S., Ph.D. 
                               
                              Professor and Head  
                           
                         
                                  
         
                                                    
                                                    
                            St. Johns Research Institute 
                           
                                                                              
                            Molecular Medicine division 
                           
                                                                              
                            St. Johns National Academy of Health Sciences 
                           
                                                    
                            Bangalore - 560 034                                 
                           
                                                    
                            Karnataka                                 
                           						  
                                                            
                           
                                                    
                            E-mail: tssridharin@yahoo.com 
                           
                                                                              
                            Phone: +91-80-25532037, 22065059 
                           
                          
                               
                           
                          
                            URL:   http://sjri.res.in/per-pages/per-sridhar_ts.html  
                           
                          
                          						  
                              
                           
						  
	                             
                            Positions Held:  
                           
                                                    
                            
                                
                                  Position  
                                  Affiliation  
                                  Time Period   
                                 
                                                                
                                  Resident  
                                  Barnes Hospital, Washington University, St. Louis, USA 
                                  
								  1997-2000 
                                 
                                                                
                                  Post Doctoral Fellow  
                                  Harvard Medical School, Boston, USA 
                                  
								  1993-1996 
                                 
                                                            
 
                           
                          
                              
                           
                                                                              
                            Area of Specialization:  
                           
                          
                          
  
     
    Molecular Biology 
   
     
                          
                        
                           
                           
                         
                         
                                                    
                                                    
                          
                             
                           
                                                    
                             Research Summary:  
                           
                                                    
                            
                                                                
                                   
                                  Biomarkers in cancer diagnosis and therapy, specifically breast cancer and malignant gliomas 
                                 
                                                                
                                   
                                  Development of novel chemotherapeutics for cancer 
                                 
                                                                
                                   
                                  Molecular mechanisms of neurodegeneration and neuroprotection 
                                 
                                                            
 
                           
                          
                              
                           
                                                    
                            Publications:  
                           
                          
                            
	
		
			
				1. 
			
				Somayajulu-Nitu, M., Sandhu, J. K., Cohen, J., Sikorska, M., Sridhar, T. S. , Matei, A., Borowy-Borowski, H. and Pandey, S.  Paraquat induces oxidative stress, neuronal loss in substantia nigra region and parkinsonism in adult rats: neuroprotection and amelioration of symptoms by water-soluble formulation of coenzyme Q10. BMC Neuroscience.  2009.  10, 88. [PubMed]  
		 
		
			
				2. 
			
				Siedlakowski, P., McLachlan-Burgess, A., Griffin, C.,Sridhar T. S.,  Tirumalai, S. S., McNulty, J. and Pandey, S.  Synergy of Pancratistatin and Tamoxifen on breast cancer cells in inducing apoptosis by targeting mitochondria. Cancer Biology & Therapy.  2008. 7, 376-384. 
		 
		
			
				3. 
			
				Siedlakowski, P., McLachlan-Burgess, A., Griffin, C., Tirumalai, S. S. , McNulty, J. and Pandey, S.  Synergy of Pancratistatin and Tamoxifen on breast cancer cells in inducing apoptosis by targeting mitochondria. Cancer Biology & Therapy.  2008.  7, 376-384. [PubMed]  
		 
	 
	
		
			
				4. 
			
				Pandey, V., Prabhu, J. S., Payal, K., Rajan, V., Deepak, C., Barde, S., Jagannath, P., Borges, A. and Sridhar, T. S.   Assessment of microsatellite instability in colorectal carcinoma at an Indian center. International Journal of Colorectal Disease.  2007.  22, 777-782. [PubMed]  
		 
		
			
				5. 
			
				Sridhar, T. S. , Brown, M. C. and Sewell, W. F.  Unique postsynaptic signaling at the hair cell efferent synapse permits calcium to evoke changes on two time scales. The Journal of Neuroscience.  1997.  17, 428-437. [PubMed]  
		 
		
			
				6. 
			
				Sridhar, T. S. , Liberman, M. C., Brown, M. C. and Sewell, W. F.  A novel cholinergic "slow effect" of efferent stimulation on cochlear potentials in the guinea pig. The Journal of Neuroscience.  1995.  15, 3667-3678. [PubMed]  
		 
		
			
				7. 
			
				Sridhar, T. S. , Swarup, G. and Khar, A.  Downregulation of phospho-tyrosine phosphatases in a macrophage tumor. FEBS Letters.  1993.  326, 75-79. [PubMed]  
		 
		
			
				8. 
			
				Sridhar, T. S.  and Sohi, H. S.  Control of anthracnose of banana caused by Gloeosporium musarum Cke. & Massee in storage with the use of fungicidal treatments. Hindustan Antibiotics Bulletin.  1974.  17, 35-36. [PubMed]  
		 
		
			
				9. 
			
				Sridhar T. S.   Evaluation of fungicides against Rhizopus spp causing soft rot of fruits. Hindustan Antibiotics Bulletin.  1974.  17, 31-34. [PubMed]  
		 
	 
	 
  
                           
                         
                                                
 
                      
                          
                            
                                                                 
                                   
                             
                            
                                
                             
                            
                              
                                  
                                     
                                   
                                  
                                                                            
                                        
                                                                                    
                                            Education  
 
                                           
                                                                                    
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                                            M.B.B.S.                                                    				
				 
                                                    Kasturba Medical College, Manipal University, Manipal, India                                                                        
 
                                           
                                                                                    
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                                            Ph.D.                                                    				
				 
                                                    Centre for Cellular and Molecular Biology, Hyderabad, India                                                                        
 
                                           
                                                                                    
                                            Honors and Awards  
 
                                           
                                                                                    
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                                            1992, The Upjohn award for cancer research at the 83rd annual meeting of the American Association for Cancer Research, San Diego USA                       
 
                                           
                                                                                    
                                            Member 
 
                                           
                                                                                    
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                                            Executive Member, Indian Association of Medical & Pediatric Oncology and Indian Society for Oncology                       
 
                                           
                                                                                  
                                       
                                       
                                   
                              
 
                             
                          
                        
                            
                               
                             
                            
                                                                
                                  
                                    
                                      Type of Neoplasms 
 
                                     
                                                                                                                                                                                    
                                      Breast 
 
                                     
									                                    
                                      
                                          Female