T. S. Sridhar, M.B.B.S., Ph.D.
Professor and Head
St. Johns Research Institute
Molecular Medicine division
St. Johns National Academy of Health Sciences
Bangalore - 560 034
Karnataka
E-mail: tssridharin@yahoo.com
Phone: +91-80-25532037, 22065059
URL: http://sjri.res.in/per-pages/per-sridhar_ts.html
Positions Held:
Position
Affiliation
Time Period
Resident
Barnes Hospital, Washington University, St. Louis, USA
1997-2000
Post Doctoral Fellow
Harvard Medical School, Boston, USA
1993-1996
Area of Specialization:
Molecular Biology
Research Summary:
Biomarkers in cancer diagnosis and therapy, specifically breast cancer and malignant gliomas
Development of novel chemotherapeutics for cancer
Molecular mechanisms of neurodegeneration and neuroprotection
Publications:
1.
Somayajulu-Nitu, M., Sandhu, J. K., Cohen, J., Sikorska, M., Sridhar, T. S. , Matei, A., Borowy-Borowski, H. and Pandey, S. Paraquat induces oxidative stress, neuronal loss in substantia nigra region and parkinsonism in adult rats: neuroprotection and amelioration of symptoms by water-soluble formulation of coenzyme Q10. BMC Neuroscience. 2009. 10, 88. [PubMed]
2.
Siedlakowski, P., McLachlan-Burgess, A., Griffin, C.,Sridhar T. S., Tirumalai, S. S., McNulty, J. and Pandey, S. Synergy of Pancratistatin and Tamoxifen on breast cancer cells in inducing apoptosis by targeting mitochondria. Cancer Biology & Therapy. 2008. 7, 376-384.
3.
Siedlakowski, P., McLachlan-Burgess, A., Griffin, C., Tirumalai, S. S. , McNulty, J. and Pandey, S. Synergy of Pancratistatin and Tamoxifen on breast cancer cells in inducing apoptosis by targeting mitochondria. Cancer Biology & Therapy. 2008. 7, 376-384. [PubMed]
4.
Pandey, V., Prabhu, J. S., Payal, K., Rajan, V., Deepak, C., Barde, S., Jagannath, P., Borges, A. and Sridhar, T. S. Assessment of microsatellite instability in colorectal carcinoma at an Indian center. International Journal of Colorectal Disease. 2007. 22, 777-782. [PubMed]
5.
Sridhar, T. S. , Brown, M. C. and Sewell, W. F. Unique postsynaptic signaling at the hair cell efferent synapse permits calcium to evoke changes on two time scales. The Journal of Neuroscience. 1997. 17, 428-437. [PubMed]
6.
Sridhar, T. S. , Liberman, M. C., Brown, M. C. and Sewell, W. F. A novel cholinergic "slow effect" of efferent stimulation on cochlear potentials in the guinea pig. The Journal of Neuroscience. 1995. 15, 3667-3678. [PubMed]
7.
Sridhar, T. S. , Swarup, G. and Khar, A. Downregulation of phospho-tyrosine phosphatases in a macrophage tumor. FEBS Letters. 1993. 326, 75-79. [PubMed]
8.
Sridhar, T. S. and Sohi, H. S. Control of anthracnose of banana caused by Gloeosporium musarum Cke. & Massee in storage with the use of fungicidal treatments. Hindustan Antibiotics Bulletin. 1974. 17, 35-36. [PubMed]
9.
Sridhar T. S. Evaluation of fungicides against Rhizopus spp causing soft rot of fruits. Hindustan Antibiotics Bulletin. 1974. 17, 31-34. [PubMed]
Education
::
M.B.B.S.
Kasturba Medical College, Manipal University, Manipal, India
::
Ph.D.
Centre for Cellular and Molecular Biology, Hyderabad, India
Honors and Awards
::
1992, The Upjohn award for cancer research at the 83rd annual meeting of the American Association for Cancer Research, San Diego USA
Member
::
Executive Member, Indian Association of Medical & Pediatric Oncology and Indian Society for Oncology
Type of Neoplasms
Breast
Female