Mahesh  J  Kulkarni,                               Ph.D. 
                               
                              Scientist  
                           
                         
                                  
         
                                                    
                                                                              
                            Dr. Homi Bhabha Road 
                           
                                                                              
                            Pune - 411 008                                 
                           
                                                    
                            Maharashtra                                 
                           						  
                                                            
                           
                                                    
                            E-mail: mj.kulkarni@ncl.res.in 
                           
                                                                              
                            Phone: +91-20-25902541 
                           
                                                    
                            Fax: +91-20-25902648  
                           
                  
                          
                               
                           
                          
                            URL:   http://www.ncl-india.org/files/Research/ScientistProfile/Default.aspx?menuid=ql8&Id=5&NCLEmpId=2365&UserId=47  
                           
                          
                          						  
                              
                           
						  
	                                                       
                            Publications:  
                           
                          
                            
	
		
			
				1. 
			
				Kesavan, S. K., Bhat, S., Golegaonkar, S. B., Jagadeeshaprasad, M. G., Deshmukh, A. B., Patil, H. S., Bhosale, S. D., Shaikh, M. L., Thulasiram, H. V., Boppana, R. and Kulkarni, M. J.  Proteome wide reduction in AGE modification in streptozotocin induced diabetic mice by hydralazine mediated transglycation. Scientific Reports.  2013.  3, 2941. [PubMed]  
		 
		
			
				2. 
			
				Joglekar, M. M., Panaskar, S. N., Chougale, A. D., Kulkarni, M. J. and Arvindekar, A. U.  A novel mechanism for antiglycative action of limonene through stabilization of protein conformation. Molecular BioSystems.  2013.  9, 2463-2472. [PubMed]  
		 
		
			
				3. 
			
				Jangale, N. M., Devarshi, P. P., Dubal, A. A., Ghule, A. E., Koppikar, S. J., Bodhankar, S. L., Chougale, A. D., Kulkarni, M. J. and Harsulkar, A. M.  Dietary flaxseed oil and fish oil modulates expression of antioxidant and inflammatory genes with alleviation of protein glycation status and inflammation in liver of streptozotocin-nicotinamide induced diabetic rats. Food Chemistry.  2013.  141, 187-195. [PubMed]  
		 
		
			
				4. 
			
				Korwar, A. M., Bhonsle, H. S., Ghole, V. S., Gawai, K. R., Koppikar, C. B. and Kulkarni, M. J.  Proteomic profiling and interactome analysis of ER-positive/HER2/neu negative invasive ductal carcinoma of the breast: towards proteomics biomarkers. Omics : A Journal of Integrative Biology.  2013.  17, 27-40. [PubMed]  
		 
		
			
				5. 
			
				Bhonsle, H. S., Korwar, A. M., Chougale, A. D., Kote, S. S., Dhande, N. L., Shelgikar, K. M. and Kulkarni, M. J.  Proteomic study reveals downregulation of apolipoprotein A1 in plasma of poorly controlled diabetes: a pilot study. Molecular Medicine Reports.  2013.  7, 495-498. [PubMed]  
		 
		
			
				6. 
			
				Kulkarni, M. J., Korwar, A. M., Mary, S., Bhonsle, H. S. and Giri, A. P.  Glycated proteome: from reaction to intervention. Proteomics. Clinical Applications.  2013.  7, 155-170. [PubMed]  
		 
		
			
				7. 
			
				Mishra, M., Mahajan, N., Tamhane, V. A., Kulkarni, M. J., Baldwin, I. T., Gupta, V. S. and Giri, A. P.  Stress inducible proteinase inhibitor diversity in Capsicum annuum. BMC Plant Biology.  2012.  12, 217. [PubMed]  
		 
		
			
				8. 
			
				Bansode, S. B., Chougale, A. D., Joshi, R. S., Giri, A. P., Bodhankar, S. L., Harsulkar, A. M. and Kulkarni, M. J.  Proteomic analysis of protease resistant proteins in the diabetic rat kidney. Molecular & Cellular Proteomics : MCP.  2013.  12, 228-236. [PubMed]  
		 
		
			
				9. 
			
				Mary, S., Patil, G. V., Kulkarni, A. V., Kulkarni, M. J., Joshi, S. R., Mehendale, S. S. and Giri, A. P.  Dynamic proteome in enigmatic preeclampsia: an account of molecular mechanisms and biomarker discovery. Proteomics. Clinical Applications.  2012.  6, 79-90. [PubMed]  
		 
		
			
				10. 
			
				Korwar, A. M., Bhonsle, H. S., Chougale, A. D., Kote, S. S., Gawai, K. R., Ghole, V. S., Koppikar, C. B. and Kulkarni, M. J.  Analysis of AGE modified proteins and RAGE expression in HER2/neu negative invasive ductal carcinoma. Biochemical and Biophysical Research Communications.  2012.  419, 490-494. [PubMed]  
		 
		
			
				11. 
			
				Bhonsle, H. S., Korwar, A. M., Kesavan, S. K., Bhosale, S. D., Bansode, S. B. and Kulkarni, M. J.  "Zoom-ln"--A targeted database search for identification of glycation modifications analyzed by untargeted tandem mass spectrometry. European Journal of Mass Spectrometry.  2012.  18, 475-481. [PubMed]  
		 
		
			
				12. 
			
				Bhonsle, H. S., Korwar, A. M., Kote, S. S., Golegaonkar, S. B., Chougale, A. D., Shaik, M. L., Dhande, N. L., Giri, A. P., Shelgikar, K. M., Boppana, R. and Kulkarni, M. J.  Low plasma albumin levels are associated with increased plasma protein glycation and HbA1c in diabetes. Journal of Proteome Research.  2012.  11, 1391-1396. [PubMed]  
		 
		
			
				13. 
			
				Suresh, K. K., Bhosale, S. D., Thulasiram, H. V. and Kulkarni, M. J.  Comparative and chemical proteomic approaches reveal gatifloxacin deregulates enzymes involved in glucose metabolism. The Journal of Toxicological Sciences.  2011.  36, 787-796. [PubMed]  
		 
		
			
				14. 
			
				Chougale, A. D., Bhat, S. P., Bhujbal, S. V., Zambare, M. R., Puntambekar, S., Somani, R. S., Boppana, R., Giri, A. P. and Kulkarni, M. J.  Proteomic analysis of glycated proteins from streptozotocin-induced diabetic rat kidney. Molecular Biotechnology.  2012.  50, 28-38. [PubMed]  
		 
		
			
				15. 
			
				Mishra, M., Tamhane, V. A., Khandelwal, N., Kulkarni, M. J., Gupta, V. S. and Giri, A. P.  Interaction of recombinant CanPIs with Helicoverpa armigera gut proteases reveals their processing patterns, stability and efficiency. Proteomics.  2010.  10, 2845-2857. [PubMed]  
		 
		
			
				16. 
			
				Golegaonkar, S. B., Bhonsle, H. S., Boppana, R. and Kulkarni, M. J.  Discovery of rifampicin as a new anti-glycating compound by matrix-assisted laser desorption/ionization mass spectrometry-based insulin glycation assay. European Journal of Mass Spectrometry.  2010.  16, 221-226. [PubMed]  
		 
		
			
				17. 
			
				Dhaneshwar, S. R., Mahadik, M. V. and Kulkarni, M. J.  Column liquid chromatography-ultraviolet and column liquid chromatography/mass spectrometry evaluation of stress degradation behavior of escitalopram oxalate. Journal of AOAC International.  2009.  92, 138-147. [PubMed]  
		 
		
			
				18. 
			
				Bhonsle, H. S., Singh, S. K., Srivastava, G., Boppana, R. and Kulkarni, M. J.  Albumin competitively inhibits glycation of less abundant proteins. Protein and Peptide Letters.  2008.  15, 663-667. [PubMed]  
		 
		
			
				19. 
			
				Shabab, M., Kulkarni, M. J. and Khan, M. I.  Study of papain-cystatin interaction by intensity fading MALDI-TOF-MS. The Protein Journal.  2008.  27, 7-12. [PubMed]  
		 
		
			
				20. 
			
				Bar, C., Patil, R., Doshi, J., Kulkarni, M. J. and Gade, W. N.  Characterization of the proteins of bacterial strain isolated from contaminated site involved in heavy metal resistance--a proteomic approach. Journal of Biotechnology.  2007.  128, 444-451. [PubMed]  
		 
		
			
				21. 
			
				Kulkarni, M. J., Vinod, V. P., Umasankar, P. K., Patole, M. S. and Rao, M.  Intact cell matrix-assisted laser desorption/ionization mass spectrometry as a tool to screen drugs in vivo for regulation of protein expression. Rapid Communications in Mass Spectrometry : RCM.  2006.  20, 2769-2772. [PubMed]  
		 
		
			
				22. 
			
				Chumbalkar, V. C., Subhashini, C., Dhople, V. M., Sundaram, C. S., Jagannadham, M. V., Kumar, K. N., Srinivas, P. N., Mythili, R., Rao, M. K., Kulkarni, M. J., Hegde, S., Hegde, A. S., Samual, C., Santosh, V., Singh, L. and Sirdeshmukh, R.  Differential protein expression in human gliomas and molecular insights. Proteomics.  2005.  5, 1167-1177. [PubMed]  
		 
	 
	 
  
                           
                         
                                                    
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                                            Education  
 
                                           
                                                                                    
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                                            Ph.D.                                                    				
				 
                                                    University of Agricultural Sciences, Bangalore                                                                        
 
                                           
                                                                                    
                                            Honors and Awards  
 
                                           
                                                                                    
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                                            NCL Research Foundation - Scientist of the year 2010 
 
                                           
                                                                                    
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                                            Elected as Young Associate of Maharashtra Academy of Sciences, 2007 
 
                                           
                                                                                    
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                                            Executive council member of Proteomics Society, India from 2009