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Arun Kumar, Ph.D.
Indian Institute of Science
Molecular Reproduction Development and Genetics Indian Institute of Science
Bangalore - 560 012   
Phone: 91-80-22932998
Fax:  91-80-23600999
1.Rather, M. I., Swamy, S., Gopinath, K. S. and Kumar, A.  Transcriptional repression of tumor suppressor CDC73, encoding an RNA polymerase II interactor, by WT1 promotes cell proliferation: implication for cancer therapeutics. The Journal of Biological Chemistry. 2013.  [PubMed]
2.Venkatesh, T., Nagashri, M. N., Swamy, S. S., Mohiyuddin, S. M., Gopinath, K. S. and Kumar, A.  Primary microcephaly gene MCPH1 shows signatures of tumor suppressors and is regulated by miR-27a in oral squamous cell carcinoma. PloS One. 2013.  8, e54643. [PubMed]
3.Rather, M. I., Nagashri, M. N., Swamy, S. S., Gopinath, K. S. and Kumar, A.  Oncogenic microRNA-155 down-regulates tumor suppressor CDC73 and promotes oral squamous cell carcinoma cell proliferation: implications for cancer therapeutics. The Journal of Biological Chemistry. 2013.  288, 608-618. [PubMed]
4.Kapoor, S., Bindu, P. S., Taly, A. B., Sinha, S., Gayathri, N., Rani, S. V., Chandak, G. R. and Kumar, A.  Genetic analysis of an Indian family with members affected with Waardenburg syndrome and Duchenne muscular dystrophy. Molecular Vision. 2012.  18, 2022-2032. [PubMed]
5.Somasundaram, J., Krishnasamy, R., Savithri, P., Mahimairaja, S., Kumar, B. S., Sivasubramanium, K., Kumar, V. A., Poongothai, S., Coumar, M. V. and Behera, S. K.  Accumulation of few heavy metals in sewage sludges, soils and plants of Coimbatore, Tamil Nadu (India). Journal of Environmental Science & Engineering. 2012.  54, 27-42. [PubMed]
6.Pradhan, S., Nagashri, M. N., Gopinath, K. S. and Kumar, A.  Expression profiling of CYP1B1 in oral squamous cell carcinoma: counterintuitive downregulation in tumors. PloS One. 2011.  6, e27914. [PubMed]
7.Singhmar, P. and Kumar, A.  Angelman syndrome protein UBE3A interacts with primary microcephaly protein ASPM, localizes to centrosomes and regulates chromosome segregation. PloS One. 2011.  6, e20397. [PubMed]
8.Kumar, A., Duvvari, M. R., Prabhakaran, V. C., Shetty, J. S., Murthy, G. J. and Blanton, S. H.  A homozygous mutation in LTBP2 causes isolated microspherophakia. Human Genetics. 2010.  128, 365-371. [PubMed]
9.Kumar, A., Girimaji, S. C., Duvvari, M. R. and Blanton, S. H.  Mutations in STIL, encoding a pericentriolar and centrosomal protein, cause primary microcephaly. American Journal of Human Genetics. 2009.  84, 286-290. [PubMed]
10.Ali, A. M., Bajaj, V., Gopinath, K. S. and Kumar, A.  Characterization of the human SLC22A18 gene promoter and its regulation by the transcription factor Sp1. Gene. 2009.  429, 37-43. [PubMed]
11.Bajaj, V., Singhmar, P. and Kumar, A.  Promoter characterization and regulation of expression of an imprinted gene SLC22A18AS. Gene. 2008.  424, 40-47. [PubMed]
12.Chakraborty, S., Mohiyuddin, S. M., Gopinath, K. S. and Kumar, A.  Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma. BMC Cancer. 2008.  8, 163. [PubMed]
13.Kumar, A., Kumar, D., Prabhakaran, V. C., Prakash, D. R. and Chakraborty, S.  Identification of genes associated with tumorigenesis of meibomian cell carcinoma by microarray analysis. Genomics. 2007.  90, 559-566. [PubMed]
14.Chakraborty, S., Khare, S., Dorairaj, S. K., Prabhakaran, V. C., Prakash, D. R. and Kumar, A.  Identification of genes associated with tumorigenesis of retinoblastoma by microarray analysis. Genomics. 2007.  90, 344-353. [PubMed]
15.Kumar, A., Basavaraj, M. G., Gupta, S. K., Qamar, I., Ali, A. M., Bajaj, V., Ramesh, T. K., Prakash, D. R., Shetty, J. S. and Dorairaj, S. K.  Role of CYP1B1, MYOC, OPTN, and OPTC genes in adult-onset primary open-angle glaucoma: predominance of CYP1B1 mutations in Indian patients. Molecular Vision. 2007.  13, 667-676. [PubMed]
16.Kumar, A., Bhattacharjee, S., Prakash, D. R. and Sadanand, C. S.  Genetic analysis of two Indian families affected with congenital hereditary endothelial dystrophy: two novel mutations in SLC4A11. Molecular Vision. 2007.  13, 39-46. [PubMed]
17.Ali, M., Venkatesh, C., Ragunath, A. and Kumar, A.  Mutation analysis of the KIF21A gene in an Indian family with CFEOM1: implication of CpG methylation for most frequent mutations. Ophthalmic Genetics. 2004.  25, 247-255. [PubMed]
18.Kumar, A., Babu, M., Kimberling, W. J. and Venkatesh, C. P.  Genetic analysis of a four generation Indian family with Usher syndrome: a novel insertion mutation in MYO7A. Molecular Vision. 2004.  10, 910-916. [PubMed]
19.Kumar, A., Babu, M., Raghunath, A. and Venkatesh, C. P.  Genetic analysis of a five generation Indian family with BPES: a novel missense mutation (p.Y215C). Molecular Vision. 2004.  10, 445-449. [PubMed]
20.Kumar, A., Shetty, J., Kumar, B. and Blanton, S. H.  Confirmation of linkage and refinement of the RP28 locus for autosomal recessive retinitis pigmentosa on chromosome 2p14-p15 in an Indian family. Molecular Vision. 2004.  10, 399-402. [PubMed]
21.Bajaj, V., Markandaya, M., Krishna, L. and Kumar, A.  Paternal imprinting of the SLC22A1LS gene located in the human chromosome segment 11p15.5. BMC Genetics. 2004.  5, 13. [PubMed]
22.Ali, M., Girimaji, S. C. and Kumar, A.  Identification of a core promoter and a novel isoform of the human TSC1 gene transcript and structural comparison with mouse homolog. Gene. 2003.  320, 145-154. [PubMed]
23.Selvaraju, V., Markandaya, M., Prasad, P. V., Sathyan, P., Sethuraman, G., Srivastava, S. C., Thakker, N. and Kumar, A.  Mutation analysis of the cathepsin C gene in Indian families with Papillon-Lefevre syndrome. BMC Medical Genetics. 2003.  4, 5. [PubMed]
24.Kumar, A., Markandaya, M. and Girimaji, S. C.  Primary microcephaly: microcephalin and ASPM determine the size of the human brain. Journal of Biosciences. 2002.  27, 629-632. [PubMed]
Honors and Awards
Fellow of the American college of Medical Genetics(Elected in 2000)
  Last modified on : Dec 9, 2013
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.