INCREDB ID : 451
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Anjali Shiras,
Scientific Officer F 
 
National Centre for Cell Science
NCCS Complex, Pune University Campus
Ganeshkhind
Pune - 411 007   
Maharashtra   
 
E-mail: anjalishiras@nccs.res.in
Phone: +91-020-25708052
Fax: +91-020-25692259
 
URL: http://www.nccs.res.in/anjalis.html
 
Research Summary:
Understanding the role of cellular signaling pathways involved in cancer stemness and malignant behavior of Central Nervous System (CNS) tumors
 
Publications:
1.Murawala, P., Tirmale, A., Shiras, A. and Prasad, B. L.  In situ synthesized BSA capped gold nanoparticles: Effective carrier of anticancer drug Methotrexate to MCF-7 breast cancer cells. Materials Science & Engineering. C, Materials For Biological Applications. 2014.  34, 158-167. [PubMed]
2.Rani, S. B., Rathod, S. S., Karthik, S., Kaur, N., Muzumdar, D. and Shiras, A. S.  MiR-145 functions as a tumor-suppressive RNA by targeting Sox9 and adducin 3 in human glioma cells. Neuro-oncology. 2013.  15, 1302-1316. [PubMed]
3.Gupta, M. K., Polisetty, R. V., Ramamoorthy, K., Tiwary, S., Kaur, N., Uppin, M. S., Shiras, A. and Sirdeshmukh, R.  Secretome analysis of Glioblastoma cell line--HNGC-2. Molecular BioSystems. 2013.  9, 1390-1400. [PubMed]
4.Kaur, N., Chettiar, S., Rathod, S., Rath, P., Muzumdar, D., Shaikh, M. L. and Shiras, A.  Wnt3a mediated activation of Wnt/beta-catenin signaling promotes tumor progression in glioblastoma. Molecular and Cellular Neurosciences. 2013.  54, 44-57. [PubMed]
5.Polisetty, R. V., Gupta, M. K., Nair, S. C., Ramamoorthy, K., Tiwary, S., Shiras, A., Chandak, G. R. and Sirdeshmukh, R.  Glioblastoma cell secretome: analysis of three glioblastoma cell lines reveal 148 non-redundant proteins. Journal of Proteomics. 2011.  74, 1918-1925. [PubMed]
6.Mruthyunjaya, S., Rumma, M., Ravibhushan, G., Anjali, S. and Padma, S.  c-Jun/AP-1 transcription factor regulates laminin-1-induced neurite outgrowth in human bone marrow mesenchymal stem cells: role of multiple signaling pathways. FEBS Letters. 2011.  585, 1915-1922. [PubMed]
7.Das, G., Shiras, A., Shanmuganandam, K. and Shastry, P.  Rictor regulates MMP-9 activity and invasion through Raf-1-MEK-ERK signaling pathway in glioma cells. Molecular Carcinogenesis. 2011.  50, 412-423. [PubMed]
8.Joshi-Navare, K., Shiras, A. and Prabhune, A.  Differentiation-inducing ability of sophorolipids of oleic and linoleic acids using a glioma cell line. Biotechnology Journal. 2011.  6, 509-512. [PubMed]
9.Venkatpurwar, V., Shiras, A. and Pokharkar, V.  Porphyran capped gold nanoparticles as a novel carrier for delivery of anticancer drug: in vitro cytotoxicity study. International Journal of Pharmaceutics. 2011.  409, 314-320. [PubMed]
10.Rajendran, G., Shanmuganandam, K., Bendre, A., Muzumdar, D., Goel, A. and Shiras, A.  Epigenetic regulation of DNA methyltransferases: DNMT1 and DNMT3B in gliomas. Journal of Neuro-oncology. 2011.  104, 483-494. [PubMed]
11.Dhar, S., Mali, V., Bodhankar, S., Shiras, A., Prasad, B. L. and Pokharkar, V.  Biocompatible gellan gum-reduced gold nanoparticles: cellular uptake and subacute oral toxicity studies. Journal of Applied Toxicology : JAT. 2011.  31, 411-420. [PubMed]
12.Dhar, S., Reddy, E. M., Prabhune, A., Pokharkar, V., Shiras, A. and Prasad, B. L.  Cytotoxicity of sophorolipid-gellan gum-gold nanoparticle conjugates and their doxorubicin loaded derivatives towards human glioma and human glioma stem cell lines. Nanoscale. 2011.  3, 575-580. [PubMed]
13.Reddy, E. M., Chettiar, S. T., Kaur, N., Shepal, V. and Shiras, A.  Dlxin-1, a MAGE family protein, induces accelerated neurite outgrowth and cell survival by enhanced and early activation of MEK and Akt signalling pathways in PC12 cells. Experimental Cell Research. 2010.  316, 2220-2236. [PubMed]
14.Mruthyunjaya, S., Manchanda, R., Godbole, R., Pujari, R., Shiras, A. and Shastry, P.  Laminin-1 induces neurite outgrowth in human mesenchymal stem cells in serum/differentiation factors-free conditions through activation of FAK-MEK/ERK signaling pathways. Biochemical and Biophysical Research Communications. 2010.  391, 43-48. [PubMed]
15.Dhar, S., Reddy, E. M., Shiras, A., Pokharkar, V. and Prasad, B. L.  Natural gum reduced/stabilized gold nanoparticles for drug delivery formulations. Chemistry. 2008.  14, 10244-10250. [PubMed]
16.Sudheerkumar, P., Shiras, A., Das, G., Jagtap, J. C., Prasad, V. and Shastry, P.  Independent activation of Akt and NF-kappaB pathways and their role in resistance to TNF-alpha mediated cytotoxicity in gliomas. Molecular Carcinogenesis. 2008.  47, 126-136. [PubMed]
17.Kumar, P. S., Shiras, A., Das, G., Jagtap, J. C., Prasad, V. and Shastry, P.  Differential expression and role of p21cip/waf1 and p27kip1 in TNF-alpha-induced inhibition of proliferation in human glioma cells. Molecular Cancer. 2007.  6, 42. [PubMed]
18.Shiras, A., Chettiar, S. T., Shepal, V., Rajendran, G., Prasad, G. R. and Shastry, P.  Spontaneous transformation of human adult nontumorigenic stem cells to cancer stem cells is driven by genomic instability in a human model of glioblastoma. Stem Cells. 2007.  25, 1478-1489. [PubMed]
19.Shiras, A., Bhosale, A., Shepal, V., Shukla, R., Baburao, V. S., Prabhakara, K. and Shastry, P.  A unique model system for tumor progression in GBM comprising two developed human neuro-epithelial cell lines with differential transforming potential and coexpressing neuronal and glial markers. Neoplasia. 2003.  5, 520-532. [PubMed]
20.Shiras, A., Bhosale, A., Patekar, A., Shepal, V. and Shastry, P.  Differential expression of CD44(S) and variant isoforms v3, v10 in three-dimensional cultures of mouse melanoma cell lines. Clinical & Experimental Metastasis. 2002.  19, 445-455. [PubMed]
 
  Last modified on : Dec 3, 2013
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