Mahitosh Mandal, Ph.D.
Indian Institute of Technology
Medical Science & Technology
IIT Campus
Kharagpur - 721 302
West Bengal
E-mail: mahitosh@smst.iitkgp.ernet.in
Phone: +91 - 3222 - 283578, +91 - 3222 - 283579
URL: http://www.iitkgp.ac.in/fac-profiles/showprofile.php?empcode=bXmdY
Positions Held:
Position Affiliation Time Period
Associate Professor
Indian Institute of Technology, Kharagpur
2006-Present
Area of Specialization:
Cancer Biology
Research Summary:
Cancer Biology
Signal Transduction
Apoptosis
Cell Cycle
Agiogenesis
Drug delivery
Publications:
1. Das, R., Mitra, G., Mathew, B., Ross, C., Bhat, V. and Mandal, A. K. Automated analysis of hemoglobin variants using nanoLC-MS and customized databases. Journal of Proteome Research. 2013. 12, 3215-3222. [PubMed] 2. Gaikwad, T., Ghosh, K., Kulkarni, B., Kulkarni, V., Ross, C. and Shetty, S. Influence of CYP2C9 and VKORC1 gene polymorphisms on warfarin dosage, over anticoagulation and other adverse outcomes in Indian population. European Journal of Pharmacology. 2013. 710, 80-84. [PubMed] 3. Alwar, V. A., Rameshkumar, K. and Ross, C. ABO blood groups and malaria related clinical outcome. Journal of Vector Borne Diseases. 2011. 48, 7-11. [PubMed] 4. Mahendradas, P., Shetty, R., Avadhani, K., Ross, C., Gupta, A. and Shetty, B. K. Polycythemia vera and increased hemophilic factor VIII causing acute zonal occult outer retinopathy: a case report. Ocular Immunology and Inflammation. 2010. 18, 319-321. [PubMed] 5. Ghosh, K. and Ross, C. The teacher and the taught: medical education in India at the crossroads. The National Medical Journal of India. 2009. 22, 147-149. [PubMed] 6. Krishnan, P., Fernandes, S., Savio, J., Ross, C. R., Pradeep, R., Choudhary, R., Shet, A. S. and Pais, P. Melioidosis. The Journal of the Association of Physicians of India. 2008. 56, 636-639. [PubMed] 7. Gore, M., Kelkar, P., Rege, N. and Ross, C. Reviparin sodium clivarine: a review of its therapeutic use. Journal of the Indian Medical Association. 2004. 102, 589-90. [PubMed]
1.
Sethi, K., Sarkar, S., Das, S., Mohanty, B. and Mandal, M. Biomarkers for the diagnosis of thyroid cancer. Journal of Experimental Therapeutics & Oncology. 2010. 8, 341-352. [PubMed]
2.
Talukdar, S., Mandal, M. , Hutmacher, D. W., Russell, P. J., Soekmadji, C. and Kundu, S. C. Engineered silk fibroin protein 3D matrices for in vitro tumor model. Biomaterials. 2011. 32, 2149-2159. [PubMed]
3.
Jaganathan, S. K., Mazumdar, A., Mondhe, D. and Mandal, M. Apoptotic effect of eugenol in human colon cancer cell lines. Cell Biology International. 2010. [PubMed]
4.
Mandal, S. M., Dey, S., Mandal, M. , Maria-Neto, S. and Franco, O. L. Comparative analyses of different surfactants on matrix-assisted laser desorption/ionization mass spectrometry peptide analysis. European Journal of Mass Spectrometry. 2010. 16, 567-575. [PubMed]
5.
Jaganathan, S. K., Mandal, S. M., Jana, S. K., Das, S. and Mandal, M. Studies on the phenolic profiling, anti-oxidant and cytotoxic activity of Indian honey: in vitro evaluation. Natural Product Research. 2010. 24, 1295-1306. [PubMed]
6.
Sarkar, S., Mazumdar, A., Dash, R., Sarkar, D., Fisher, P. B. and Mandal, M. ZD6474 enhances paclitaxel antiproliferative and apoptotic effects in breast carcinoma cells. Journal of Cellular Physiology. 2011. 226, 375-384. [PubMed]
7.
Jaganathan, S. K., Mondhe, D., Wani, Z. A., Pal, H. C. and Mandal, M. Effect of honey and eugenol on Ehrlich ascites and solid carcinoma. Journal of Biomedicine & Biotechnology. 2010. 2010, 989163. [PubMed]
8.
Sarkar, S., Mazumdar, A., Dash, R., Sarkar, D., Fisher, P. B. and Mandal, M. ZD6474, a dual tyrosine kinase inhibitor of EGFR and VEGFR-2, inhibits MAPK/ERK and AKT/PI3-K and induces apoptosis in breast cancer cells. Cancer Biology & Therapy. 2010. 9, 592-603. [PubMed]
9.
Venkatesan, P., Das, S., Krishnan, M. M., Chakraborty, C., Chaudhury, K. and Mandal, M. Effect of AEE788 and/or Celecoxib on colon cancer cell morphology using advanced microscopic techniques. Micron. 2010. 41, 247-256. [PubMed]
10.
Jaganathan, S. K. and Mandal, M. Involvement of non-protein thiols, mitochondrial dysfunction, reactive oxygen species and p53 in honey-induced apoptosis. Investigational New Drugs. 2010. 28, 624-633. [PubMed]
11.
Jaganathan, S. K. and Mandal, M. Antiproliferative effects of honey and of its polyphenols: a review. Journal of Biomedicine & Biotechnology. 2009. 2009, 830616. [PubMed]
12.
Mandal, S. M., Mandal, M. , Ghosh, A. K. and Dey, S. Rapid determination of vitamin B2 and B12 in human urine by isocratic liquid chromatography. Analytica Chimica Acta. 2009. 640, 110-113. [PubMed]
13.
Jaganathan, S.K. and Mandal, M. Rheology and thermal properties of marketed Indian honey. Nutrition & Food Science. 2009. 39, 111-117.
14.
Sarkar, S. and Mandal, M. Growth Factor Receptors and Apoptosis Regulators: Signaling Pathways, Prognosis, Chemosensitivity and Treatment Outcomes of Breast Cancer. Breast Cancer: Basic and Clinical Research. 2009. 3 , 47-60.
15.
Jaganathan, S.K. and Mandal, M. Honey constituents and their apoptotic effect in colon cancer cells. Journal of ApiProduct and ApiMedical Science. 2009. 1, 29 - 36.
16.
Mandal, S. M., Mandal, M. , Das, A. K., Pati, B. R. and Ghosh, A. K. Stimulation of indoleacetic acid production in a Rhizobium isolate of Vigna mungo by root nodule phenolic acids. Archives of Microbiology. 2009. 191, 389-393. [PubMed]
17.
Mandal, S. M., Dey, S., Mandal, M. , Sarkar, S., Maria-Neto, S. and Franco, O. L. Identification and structural insights of three novel antimicrobial peptides isolated from green coconut water. Peptides. 2009. 30, 633-637. [PubMed]
18.
Mandal, S. M., Ghosh, A. K. and Mandal, M. Iron oxide nanoparticle assisted purification and mass spectrometry based proteolytic mapping of intact CD4+ T cells from human blood. Preparative Biochemistry & Biotechnology. 2009. 39, 20-31. [PubMed]
19.
Dash, R., Mandal, M. , Ghosh, S. K. and Kundu, S. C. Silk sericin protein of tropical tasar silkworm inhibits UVB-induced apoptosis in human skin keratinocytes. Molecular and Cellular Biochemistry. 2008. 311, 111-119. [PubMed]
20.
Venkatesan, P., Mandal, M. Role of S100 proteins in cancer. International Journal of Medical Sciences and Technology . 2008. 1, 22-47.
21.
Mandal, M. , Saha, S., Ghosh, A. K. and Majumder, G. C. Identification and characterization of a sperm motility promoting glycoprotein from buffalo blood serum. Journal of Cellular Physiology. 2006. 209, 353-362. [PubMed]
22.
Mandal, M. , Saha, S., Ghosh, A. K. and Majumder, G.C. Identification and characterizationof a sperm motility promotingglycoprotein from buffalo blood serum. Journal of Cellular Physiology. 2006. 209, 353-362.
23.
Mandal, M. , Bandyopadhyay, D., Adam, L., Mendelsohn, J., Kumar, R. Physical interaction between epidermal growth factor receptor and DNA-protein kinase in mammalian cells. Journal of Biological Chemistry. 1998. 273. 1568-1573.
Grant Support:
Project Title Role Funding Agency Sanction Number Sanction Date
Evaluation of S100A7 (Psoriasin) as an early detection marker of squamous cell carcinoma
Principal Investigator
Department of Biotechnology, Government of India
Study of extracellular fibrillar bio polymers- natural silk fibres, silk protein scaffords and proteoglycan fibril of both mucus and extracellular mat
Co-Investigator
Department of Biotechnology, Government of India
Determining the mechanisms of S100A7 (Psoriasin) in mediating anoikis resistance and tumor progression in squamous cell carcinoma of the oral cavity
Principal Investigator
Sponsored Research & Industrial Consultancy
Purification and characterization of azurin from Pseudomonas aeruginosa 2453 & its application in human breast cancer cells
Principal Investigator
All India Council for Technical Education, Government of India
Education
::
Ph.D.
Jadavpur University
Member
::
Indian Science Congress
::
American Association for Cancer research
::
Editorial Board Member : International Journal of BioSciences and Technology
Type of Neoplasms
Head and Neck