Arambakkam Janardhanam Vanisree,                               Ph.D. 
                               
                              Assistant Professor  
                           
                         
                                  
         
                                                    
                                                    
                            University of Madras 
                           
                                                                              
                            Department of Biochemistry 
                           
                                                                              
                            Guindy Campus 
                           
                                                    
                            Chennia - 600 025                                 
                           
                                                    
                            Tamil Nadu                                 
                           						  
                                                            
                           
                                                                              
                            Phone: +91-44-2647 1075 
                           
                          
                               
                           
                          
                            URL:   http://www.unom.ac.in/departments/biochemistry/vanishree_profile.html  
                           
                          
                          						  
                              
                           
						  
	                             
                            Positions Held:  
                           
                                                    
                            
                                
                                  Position  
                                  Affiliation  
                                  Time Period   
                                 
                                                                
                                  Assistant Professor  
                                  University of Madras, Chennia, India 
                                  
								   
                                 
                                                                
                                  Lecturer  
                                  University of Madras, Chennia, India 
                                  
								   
                                 
                                                            
 
                           
                          
                              
                           
                                                                              
                            Area of Specialization:  
                           
                          
                          
                          
  
     
    Biochemistry 
   
    
                          
                        
                           
                           
                         
                         
                                                    
                                                    
                          
                             
                           
                                                    
                             Research Summary:  
                           
                                                    
                            
                                                                
                                   
                                  Neuro-Oncology 
                                 
                                                                
                                   
                                  Neurodegeneration 
                                 
                                                            
 
                           
                          
                              
                           
                                                    
                            Publications:  
                           
                          
                            
	
		
			
				1. 
			
				Sabarinathan, D., Mahalakshmi, P. and Vanisree, A. J.   Naringenin, a flavanone inhibits the proliferation of cerebrally implanted C6 glioma cells in rats. Chemico-biological Interactions.  2011.  189, 26-36. [PubMed]  
		 
		
			
				2. 
			
				Sabarinathan, D. and Vanisree, A. J.   Naringenin, a flavanone alters the tumorigenic features of C6 glioma cells. Biomedicine & Pharmacotherapy.  2010.  [PubMed]  
		 
		
			
				3. 
			
				Palani, M., Devan, S., Arunkumar, R. and Vanisree, A. J.   Frequency variations in the methylated pattern of p73/p21 genes and chromosomal aberrations correlating with different grades of glioma among south Indian population. Medical Oncology.  2010.  [PubMed]  
		 
		
			
				4. 
			
				Sabarinathan, D., Mahalakshmi, P. and Vanisree, A. J.   Naringenin promote apoptosis in cerebrally implanted C6 glioma cells. Molecular and Cellular Biochemistry.  2010.  345, 215-222. [PubMed]  
		 
		
			
				5. 
			
				Subramanian, U., Poongavanam, S. and Vanisree, A. J.   Studies on the neuroprotective role of Piper longum in C6 glioma induced rats. Investigational New Drugs.  2010.  28, 615-623. [PubMed]  
		 
		
			
				6. 
			
				Subramanian, U., Poogavanam, S. and Vanisree, A.J.  Studies on neuroprotective role of piper longum in C6 glioma induced rats. Investigational New Drugs . 2009. 
		 
		
			
				7. 
			
				Vanisree, A. J.  and Ramanan, R.  In vitro assessment of curcumin against murine neuroblastoma cells. Neuro Endocrinology Letters.  2007.  28, 204-212. [PubMed]  
		 
		
			
				8.. 
			
				Vanisree, A. J.  and Sudha, N.  Curcumin combats against cigarette smoke and ethanol-induced lipid alterations in rat lung and liver. Molecular and Cellular Biochemistry.  2006.  288, 115-123. [PubMed]  
		 
		
			
				9. 
			
				Vanisree, A. J.  and Shyamaladevi, C. S.  The effect of N-acetylcysteine in combination with vitamin C on the activity of ornithine decarboxylase of lung carcinoma cells--In vitro. Life Sciences.  2006.  79, 654-659. [PubMed]  
		 
		
			
				10. 
			
				Vani, G., Vanisree, A. J.  and Shyamaladevi, C. S.  Histone H1 inhibits the proliferation of MCF 7 and MDA MB 231 human breast cancer cells. Cell Biology International.  2006.  30, 326-331. [PubMed]  
		 
		
			
				11. 
			
				Mahendran, P., Vanisree, A. J.  and Shyamala, D.  The antiulcer activity of Garcinia cambogia extract against indomethacin-induced gastric ulcer in rats. Phytotherapy Research.   2002.  16, 80-83. [PubMed]  
		 
		
			
				12. 
			
				Vanisree, A. J.  and Shyamaladevi, C. S.  Status of lipid peroxidation and antioxidant enzymes in malignant (bronchogenic carcinoma) and non-malignant pleural effusions. Indian Journal of Cancer.  1999.  36, 127-134. [PubMed]  
		 
		
			
				13. 
			
				Vanisree, A.J. , Ramamoorthy, N. and Shyamaladevi, C.S. N-acetyl cysteine in combination with vitamin C enhances the antioxidant status of lung carcinoma cell line in vitro. Journal of Clinical Biochemistry and Nutrition . 1999. 26, 1-8. 
		 
		
			
				14. 
			
				Vanisree, A.J.  and Shyamaladevi, C.S. Effect of therapeutic strategy established by N-acetylcysteine and vitamin C on the tumor marker enzymes of lung carcinoma cell line in vitro. Indian Journal of Pharmacology . 1999. 31, 265-8. 
		 
		
			
				15. 
			
				Vanisree, A.J. , Jegadeesan, M. and Shyamaladevi, C.S. Protein-bound carbohydrates as diagnostic tools in pleural effusions of bronchogenic carcinoma patients. Lung India . 1998. 16, 14-16. 
		 
		
			
				16. 
			
				Vanisree, A.J.  and Shyamaladevi, C.S. Biochemical studies evaluating antiulcerogenic potential of UL- 409, a herbal drug formulation on experimental peptic ulcer in rats. Current Science . 1997. 73, 684-86. 
		 
		
			
				17. 
			
				Vanisree, A.J.  and Shyamaladevi, C.S. Antiulcerogenic effect of UL-409, a herbal drug formulation on experimentally induced gastric ulcer in rats. Indian Journal of Pharmacology . 1996. 28, 265-68. 
		 
		
			
				18. 
			
				Vanisree, A.J.  and Devaki, T. Biochemical studies evaluating the antiulcerogenic potential of Ocimum sanctum in experimentally induced peptic ulcer in rats. Journal of Clinical Biochemistry Nutrition . 1995. 19, 79-87. 
		 
	 
	 
  
                           
                         
                                                    
                            Grant Support:  
                           
                                                    
                            
                                
                                  Project Title  
                                  Role  
                                  Funding Agency   
                                  Sanction Number  
                                  Sanction Date  
                                 
                                                                
                                  Influence of Morinda citrifolia on Akt induced regulation of Cox-2 in experimental glioma  
                                  Principal Investigator 
                                  Health India Laboratories For WNRF 
                                   
                                  
                                  
								  
								  
								  
								  
								  
								  
								  
								  								   
                                 
                                                                
                                  Expression of Connexin 30 and impact of Damnacanthal in gap junctions of gliom 
                                  Principal Investigator 
                                  University Grants Commission, India  
                                   
                                  
                                  
								  
								  
								  
								  
								  
								  
								  
								  								   
                                 
                                                                
                                  The role of the combination of N-acetyl cysteine and vitamin C on the expression of ornithine decarboxylase in lung carcinoma cell line: involvement of Raf/Mek/Erk pathway 
                                  Principal Investigator 
                                   
                                   
                                  
                                  
								  
								  
								  
								  
								  
								  
								  
								  2005								   
                                 
                                                              
                                 
 
                           
                          
                              
                           
                                                
 
                      
                          
                            
                               
                             
                            
                                
                             
                            
                              
                                  
                                     
                                   
                                  
                                                                            
                                        
                                                                                    
                                            Education  
 
                                           
                                                                                    
                                            :: 
 
                                            Ph.D.                                                    in Biochemistry				
				 
                                                                                                                            
 
                                           
                                                                                    
                                            Member 
 
                                           
                                                                                    
                                            :: 
 
                                            Indian Academy of Neurosciences         
 
                                           
                                                                                    
                                            :: 
 
                                            Indian Association of Biomedical Scientists        
 
                                           
                                                                                    
                                            :: 
 
                                            National Academy of Biological Sciences