INCREDB ID : 261
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Subramaniam Krishnakumar, M.D.
Head of the Department 
 
Vision Research Foundation, Sankara Nethralaya
Larsen and Tubro Department of Ocular Pathology
No. 18, College Road, Nungambakkam
Chennai - 600 006   
Tamil Nadu   
 
E-mail: drkrishnakumar_2000@yahoo.com, drkk@snmail.org
Phone: +91-044-2827 1616
Mobile: 09840167482
 
URL: http://www.sankaranethralaya.org/DR-KRISHNAKUMAR-S.html
 
Positions Held:
Position Affiliation Time Period
Head of the Department Vision Research Foundation, Sankara Nethralaya, Chennia, India
Indian Council of Medical Research Fellow Nebraska Medical Center, Omaha, USA
Overseas Associate University of Missouri, Columbia, USA
Research Fellow Doheny Eye Institute, University of Southern California, USA
 
Area of Specialization:
Ophthalmology
Pathology
Research Summary:
Retinoblastoma tumor biology
Corneal and retinal stem cells
Nanomedicine
 
Publications:
1. Vandhana, S., Deepa, P. R., Jayanthi, U., Biswas, J. and Krishnakumar, S.  Clinico-pathological correlations of fatty acid synthase expression in retinoblastoma: an Indian cohort study. Experimental and Molecular Pathology. 2011.  90, 29-37. [PubMed]
2. Mallikarjuna, K., Sundaram, C. S., Sharma, Y., Deepa, P. R., Khetan, V., Gopal, L., Biswas, J., Sharma, T. and Krishnakumar, S.  Comparative proteomic analysis of differentially expressed proteins in primary retinoblastoma tumors. Proteomics. Clinical Applications. 2010.  4, 449-463. [PubMed]
3. Krishnan, S., Lakshmanan, S., Iyer, G. K., UmaMaheswari, K. and Krishnakumar, S.  The role of signaling pathways in the expansion of corneal epithelial cells in serum-free B27 supplemented medium. Molecular Vision. 2010.  16, 1169-1177. [PubMed]
4. Vandhana, S., Deepa, P. R., Aparna, G., Jayanthi, U. and Krishnakumar, S.  Evaluation of suitable solvents for testing the anti-proliferative activity of triclosan - a hydrophobic drug in cell culture. Indian Journal of Biochemistry & Biophysics. 2010.  47, 166-171. [PubMed]
5. Krishnan, S., Sudha, B. and Krishnakumar, S.  Isoforms of p63 in corneal stem cells cultured on human amniotic membrane. Biologicals : Journal of the International Association of Biological Standardization. 2010.  38, 570-576. [PubMed]
6. Mitra, M., Kandalam, M., Verma, R. S., UmaMaheswari, K. and Krishnakumar, S.  Genome-wide changes accompanying the knockdown of Ep-CAM in retinoblastoma. Molecular Vision. 2010.  16, 828-842. [PubMed]
7. Krishnan, S., Iyer, G. K. and Krishnakumar, S.  Culture & characterisation of limbal epithelial cells & oral mucosal cells. The Indian Journal of Medical Research. 2010.  131, 422-428. [PubMed]
8. Radhakrishnan, A., Badhrinarayanan, N., Biswas, J. and Krishnakumar, S.  Analysis of chromosomal aberration (1, 3, and 8) and association of microRNAs in uveal melanoma. Molecular Vision. 2009.  15, 2146-2154. [PubMed]
9. Thiyagarajan, S., Thirumalai, K., Nirmala, S., Biswas, J. and Krishnakumar, S.  Effect of curcumin on lung resistance-related protein (LRP) in retinoblastoma cells. Current Eye Research. 2009.  34, 845-851. [PubMed]
10. Sudha, B., Jasty, S., Krishnan, S. and Krishnakumar, S.  Signal transduction pathway involved in the ex vivo expansion of limbal epithelial cells cultured on various substrates. The Indian Journal of Medical Research. 2009.  129, 382-389. [PubMed]
11. Venkatesan, N., Kandalam, M., Pasricha, G., Sumantran, V., Manfioletti, G., Ono, S. J., Reddy, M. A. and Krishnakumar, S.  Expression of high mobility group A2 protein in retinoblastoma and its association with clinicopathologic features. Journal of Pediatric Hematology/oncology : Official Journal of the American Society of Pediatric Hematology/Oncology. 2009.  31, 209-214. [PubMed]
12. Balasubramanian, S., Jasty, S., Sitalakshmi, G., Madhavan, H. N. and Krishnakumar, S.  Influence of feeder layer on the expression of stem cell markers in cultured limbal corneal epithelial cells. The Indian Journal of Medical Research. 2008.  128, 616-622. [PubMed]
13. Mohan, A., Venkatesan, N., Kandalam, M., Pasricha, G., Acharya, P., Khetan, V., Gopal, L., Sharma, T., Biswas, J. and Krishnakumar, S.  Detection of human papillomavirus DNA in retinoblastoma samples: a preliminary study. Journal of Pediatric Hematology/oncology . 2009.  31, 8-13. [PubMed]
14. Sudha, B., Sitalakshmi, G., Iyer, G. K. and Krishnakumar, S.  Putative stem cell markers in limbal epithelial cells cultured on intact & denuded human amniotic membrane. The Indian Journal of Medical Research. 2008.  128, 149-156. [PubMed]
15. Sitalakshmi, G., Sudha, B., Madhavan, H. N., Vinay, S., Krishnakumar, S., Mori, Y., Yoshioka, H. and Abraham, S.  Ex vivo cultivation of corneal limbal epithelial cells in a thermoreversible polymer (Mebiol Gel) and their transplantation in rabbits: an animal model. Tissue Engineering. Part A. 2009.  15, 407-415. [PubMed]
16. Adithi, M., Nalini, V., Kandalam, M. and Krishnakumar, S.  Expression of p63 and p73 in retinoblastoma: a clinicopathological correlation study. Experimental Eye Research. 2008.  87, 312-318. [PubMed]
17. Coral, K., Angayarkanni, N., Madhavan, J., Bharathselvi, M., Ramakrishnan, S., Nandi, K., Rishi, P., Kasinathan, N. and Krishnakumar, S.  Lysyl oxidase activity in the ocular tissues and the role of LOX in proliferative diabetic retinopathy and rhegmatogenous retinal detachment. Investigative Ophthalmology & Visual Science. 2008.  49, 4746-4752. [PubMed]
18. Adithi, M., Nalini, V., Kandalam, M. and Krishnakumar, S.  Expression of matrix metalloproteinases and their inhibitors in retinoblastoma. Journal of Pediatric Hematology/oncology . 2007.  29, 399-405. [PubMed]
19. Mallikarjuna, K., Pushparaj, V., Biswas, J. and Krishnakumar, S.  Expression of epidermal growth factor receptor, ezrin, hepatocyte growth factor, and c-Met in uveal melanoma: an immunohistochemical study. Current Eye Research. 2007.  32, 281-290. [PubMed]
20. Mallikarjuna, K., Vaijayanthi, P. and Krishnakumar, S.  Cripto-1 expression in uveal melanoma: an immunohistochemical study. Experimental Eye Research. 2007.  84, 1060-1066. [PubMed]
21. Sudha, B., Madhavan, H. N., Sitalakshmi, G., Malathi, J., Krishnakumar, S., Mori, Y., Yoshioka, H. and Abraham, S.  Cultivation of human corneal limbal stem cells in Mebiol gel--A thermo-reversible gelation polymer. The Indian Journal of Medical Research. 2006.  124, 655-664. [PubMed]
22. Krishnakumar, S., Mohan, A., Kandalam, M., Ramkumar, H. L., Venkatesan, N. and Das, R. R.  SRPK1: a cisplatin sensitive protein expressed in retinoblastoma. Pediatric Blood & Cancer. 2008.  50, 402-406. [PubMed]
23. Mallikarjuna, K., Pushparaj, V., Biswas, J. and Krishnakumar, S.  Expression of insulin-like growth factor receptor (IGF-1R), c-Fos, and c-Jun in uveal melanoma: an immunohistochemical study. Current Eye Research. 2006.  31, 875-883. [PubMed]
24. Adithi, M., Venkatesan, N., Kandalam, M., Biswas, J. and Krishnakumar, S.  Expressions of Rac1, Tiam1 and Cdc42 in retinoblastoma. Experimental Eye Research. 2006.  83, 1446-1452. [PubMed]
25. Adithi, M., Kandalam, M., Ramkumar, H. L., Subramanian, A., Venkatesan, N. and Krishnakumar, S.  Retinoblastoma: expression of HLA-G. Ocular Immunology and Inflammation. 2006.  14, 207-213. [PubMed]
26. Mohan, A., Mallikarjuna, K., Venkatesan, N., Abhyankar, D., Parikh, P. M. and Krishnakumar, S.  The study of c-Src kinase and pStat3 protein expression in retinoblastoma. Experimental Eye Research. 2006.  83, 736-740. [PubMed]
27. Mohan, A., Kandalam, M., Ramkumar, H. L., Gopal, L. and Krishnakumar, S.  Stem cell markers: ABCG2 and MCM2 expression in retinoblastoma. The British Journal of Ophthalmology. 2006.  90, 889-893. [PubMed]
28. Subramanian, N., Rambhatia, S., Mahesh, L., Menon, S. V., Krishnakumar, S., Biswas, J. and Noronha, O. V.  Cystic schwannoma of the orbit-a case series. Orbit. 2005.  24, 125-129. [PubMed]
29. Agarwal, S., Shanmugam, M. P., Gopal, L., Krishnakumar, S. and Biswas, J.  Necrotic melanocytoma of the optic disk with central retinal vascular obstruction. Retina. 2005.  25, 364-367. [PubMed]
30. Krishnakumar, S., Lakshmi, S. A., Pusphparaj, V., Iyer, A., Abhyankar, D. and Biswas, J.  Human leukocyte class I antigen and beta2-microglobulin expression in conjunctival dysplasia, carcinoma in situ, and squamous cell carcinoma. Cornea. 2005.  24, 337-341. [PubMed]
31. Adithi, M., Nalini, V. and Krishnakumar, S.  The role of nitric oxide synthases and nitrotyrosine in retinoblastoma. Cancer. 2005.  103, 1701-1711. [PubMed]
32. Gopal, L., Babu, E. K., Gupta, S., Krishnakumar, S., Biswas, J. and Rao, N. A.  Pigmented malignant medulloepithelioma of the ciliary body. Journal of Pediatric Ophthalmology and Strabismus. 2004.  41, 364-366. [PubMed]
33. Krishnakumar, S., Mohan, A., Mallikarjuna, K., Venkatesan, N., Biswas, J., Shanmugam, M. P. and Ren-Heidenreich, L.  EpCAM expression in retinoblastoma: a novel molecular target for therapy. Investigative Ophthalmology & Visual Science. 2004.  45, 4247-4250. [PubMed]
34. Krishnakumar, S., Mallikarjuna, K., Desai, N., Muthialu, A., Venkatesan, N., Sundaram, A., Khetan, V. and Shanmugam, M. P.  Multidrug resistant proteins: P-glycoprotein and lung resistance protein expression in retinoblastoma. The British Journal of Ophthalmology. 2004.  88, 1521-1526. [PubMed]
35. Subramanian, N., Krishnakumar, S., Babu, K., Mohan, R., Lakshmi, K. S. and Biswas, J.  Adult onset Langerhans cell histiocytosis of the orbit--a case report. Orbit. 2004.  23, 99-103. [PubMed]
36. Menon, S. V., Shome, D., Mahesh, L., Subramanian, N., Krishnakumar, S., Biswas, J. and Noronha, O. V.  Thrombosed orbital varix -- a correlation between imaging studies and histopathology. Orbit. 2004.  23, 13-18. [PubMed]
37. Krishnakumar, S., Lakshmi, A., Shanmugam, M. P., Vanitha, K. and Biswas, J.  Nm23 expression in retinoblastoma. Ocular Immunology and Inflammation. 2004.  12, 127-135. [PubMed]
38. Krishnakumar, S., Abhyankar, D., Lakshmi, S. A., Pushparaj, V., Shanmugam, M. P. and Biswas, J.  HLA expression in choroidal melanomas: correlation with clinicopathological features. Current Eye Research. 2004.  28, 409-416. [PubMed]
39. Krishnakumar, S., Kandalam, M., Mohan, A., Iyer, A., Venkatesan, N., Biswas, J. and Shanmugam, M. P.  Expression of Fas ligand in retinoblastoma. Cancer. 2004.  101, 1672-1676. [PubMed]
40. Biswas, J., Babu, K., Krishnakumar, S. and Shanmugam, M. P.  Uveal metastasis from a bronchial carcinoid tumour. Indian Journal of Ophthalmology. 2004.  52, 160-162. [PubMed]
41. Krishnakumar, S., Rambhatla, S., Subramanian, N., Mahesh, L. and Biswas, J.  Recurrent mucinous carcinoma of the eyelid. Indian Journal of Ophthalmology. 2004.  52, 156-157. [PubMed]
42. Krishnakumar, S., Lakshmi, S. A., Abhyankar, D. and Biswas, J.  Transporter associated protein expression in uveal melanoma. The British Journal of Ophthalmology. 2004.  88, 925-928. [PubMed]
43. Biswas, J., Kabra, S., Krishnakumar, S. and Shanmugam, M. P.  Clinical and histopathological characteristics of uveal melanoma in Asian Indians. A study of 103 patients. Indian Journal of Ophthalmology. 2004.  52, 41-44. [PubMed]
44. Krishnakumar, S., Sundaram, A., Abhyankar, D., Krishnamurthy, V., Shanmugam, M. P., Gopal, L., Sharma, T. and Biswas, J.  Major histocompatibility antigens and antigen-processing molecules in retinoblastoma. Cancer. 2004.  100, 1059-1069. [PubMed]
45. Mahesh, L., Krishnakumar, S., Subramanian, N., Babu, K. and Biswas, J.  Malignant teratoma of the orbit: a clinicopathological study of a case. Orbit. 2003.  22, 305-309. [PubMed]
46. Krishnakumar, S., Lakshmi, S., Abhyankar, D. and Biswas, J.  Loss of antigen-processing molecules in primary orbital melanoma. Orbit. 2003.  22, 265-270. [PubMed]
47. Krishnakumar, S., Lakshmi, S., Abhyankar, D. and Biswas, J.  Expression of HLA class I, beta(2)-microglobulin and HLA class II antigens in primary orbital melanoma. Orbit. 2003.  22, 257-263. [PubMed]
48. Biswas, J., Babu, K., Gopal, L., Krishnakumar, S., Suresh, S. and Ramakrishnan, S.  Ocular manifestations of Wegener's granulomatosis. Analysis of nine cases. Indian Journal of Ophthalmology. 2003.  51, 217-223. [PubMed]
49. Biswas, J., Das, D., Krishnakumar, S. and Shanmugam, M. P.  Histopathologic analysis of 232 eyes with retinoblastoma conducted in an Indian tertiary-care ophthalmic center. Journal of Pediatric Ophthalmology and Strabismus. 2003.  40, 265-267. [PubMed]
50. Ganesh, S. K., Babu, K., Krishnakumar, S. and Biswas, J.  Ocular filariasis due to Wuchereria bancrofti presenting as panuveitis: a case report. Ocular Immunology and Inflammation. 2003.  11, 145-148. [PubMed]
51. Shanmugam, M. P., Lakshmi, A., Biswas, J. and Krishnakumar, S.  Prognostic significance of Fas expression in retinoblastoma. Ocular Immunology and Inflammation. 2003.  11, 107-113. [PubMed]
52. Krishnakumar, S., Abhyankar, D., Sundaram, A. L., Pushparaj, V., Shanmugam, M. P. and Biswas, J.  Major histocompatibility antigens and antigen-processing molecules in uveal melanoma. Clinical Cancer Research. 2003.  9, 4159-4164. [PubMed]
53. Krishnakumar, S., Subramanian, N., Mohan, E. R., Mahesh, L., Biswas, J. and Rao, N. A.  Solitary fibrous tumor of the orbit: a clinicopathologic study of six cases with review of the literature. Survey of Ophthalmology. 2003.  48, 544-554. [PubMed]
54. Biswas, J., Babu, K., Krishnakumar, S., Vanitha, K. and Vaijayanthi, P.  Gross photography of ophthalmic pathology specimens. Indian Journal of Ophthalmology. 2001.  49, 273-276. [PubMed]
55. Krishnakumar, S., Abhyankar, D., Lakshmi, S. A., Shanmugam, M. P., Pushparaj, V. and Biswas, J.  HLA class II antigen expression in uveal melanoma: correlation with clinicopathological features. Experimental Eye Research. 2003.  77, 175-180. [PubMed]
56. Krishnakumar, S., Mohan, E. R., Babu, K., Das, D. and Biswas, J.  Eccrine duct carcinoma of the eyelid mimicking meibomian carcinoma: clinicopathological study of a case. Survey of Ophthalmology. 2003.  48, 439-446. [PubMed]
57. Krishnakumar, S., Babu, K., Das, D. and Biswas, J.  A clinicopathologic study of sinus histiocytosis with massive lymphadenopathy mimicking an optic nerve tumor. Journal of Pediatric Ophthalmology and Strabismus. 2003.  40, 172-175. [PubMed]
58. Rambhatla, S., Subramanian, N., Gangadhara, S., Krishnakumar, S. and Biswas, J.  Myxoma of the orbit. Indian Journal of Ophthalmology. 2003.  51, 85-87. [PubMed]
59. Rajesh, M., Sulochana, K. N., Sundaram, A. L., Krishnakumar, S., Biswas, J. and Ramakrishnan, S.  Presence of a 88 kDa Eales protein in uveitis, tuberculosis, leprosy and rheumatoid arthritis. Medical Science Monitor. 2003.  9, CR95-9. [PubMed]
60. Rao, S. K., Krishnakumar, S., Sudhir, R. R., Sulochana, K. N. and Padmanabhan, P.  Bilateral corneal fibrosis in homocystinuria: case report and transmission electron microscopic findings. Cornea. 2002.  21, 730-732. [PubMed]
61. Mohan, E. R., Biswas, J. and Krishnakumar, S.  Oncocytoma of the caruncle. Indian Journal of Ophthalmology. 2002.  50, 60-61. [PubMed]
62. Sundar, J. K., Krishnakumar, S. and Biswas, J.  Retinoblastoma presenting as panophthalmitis: clinicopathological study of a case. Journal of Pediatric Ophthalmology and Strabismus. 2002.  39, 178-180. [PubMed]
63. Biswas, J., Krishnakumar, S., Bhavsar, K. and Shanmugam, M. P.  Choroidal metastasis of a gingival squamous cell carcinoma. American Journal of Ophthalmology. 2002.  133, 713-715. [PubMed]
64. Biswas, J., Raghavendra, R., Ratra, V., Krishnakumar, S., Gopal, L. and Shanmugam, M. P.  Diffuse malignant melanoma of the choroid simulating metastatic tumour in the choroid. Indian Journal of Ophthalmology. 2000.  48, 137-140. [PubMed]

 

 

 
 
Education 
::
M.D. in Pathology, University of Madras, India
Honors and Awards
::
2006-2007, Sir Sriram Travel Fellowship Award for training in proteomics by National Academy of Medical Sciences
  Last modified on : Mar 4, 2011
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