Rajat Kumar Das,                               Ph.D. 
                               
                              Senior Scientific Officer, Gr-II  
                           
                         
                                  
         
                                                    
                                                    
                            Chittaranjan National Cancer Institute 
                           
                                                                              
                            37, S. P. Mukherjee Road 
                           
                                                                              
                            Kolkata - 700 026                                 
                           
                                                    
                            West Bengal                                 
                           						  
                                                            
                           
                                                    
                            E-mail: rajatkumar.das@cnci.org.in 
                           
                                                                              
                            Phone: +91-33-24765101, Extn.327 
                           
                                                    
                            Fax: +91-33-4757606  
                           
                  
                          
                               
                           
                          
                            URL:   http://www.cnci.org.in/research/research_main.html#  
                           
                          
                          						  
                              
                           
						  
	                             
                            Positions Held:  
                           
                                                    
                            
                                
                                  Position  
                                  Affiliation  
                                  Time Period   
                                 
                                                                
                                  Senior Scientific Officer, Gr-II  
                                  Chittaranjan National Cancer Institute, Kolkata, India 
                                  
								  Present 
                                 
                                                            
 
                           
                          
                              
                           
                                                                              
                            Area of Specialization:  
                           
                          
                          
  
     
    Pharmacology 
   
    
     
    Oncology 
   
     
                          
                        
                           
                           
                         
                         
                                                    
                                                    
                          
                             
                           
                                                    
                             Research Summary:  
                           
                                                    
                            
                                                                
                                   
                                   To identify the changes in cell signaling that occur as tumors spread by metastasis and develop resistance to chemotherapy 
                                 
                                                                
                                   
                                  To identify the transcription factors that regulate gene transcription of Nucleotide Excision Repair associated genes 
                                 
                                                            
 
                           
                          
                              
                           
                                                    
                            Publications:  
                           
                          
                            
	
		
			
				1. 
			
				Das, R. K. , Hossain, S. U. and Bhattacharya, S.  Protective effect of diphenylmethyl selenocyanate against CCl4-induced hepatic injury. Journal of Applied Toxicology : JAT.  2007.  27, 527-537. [PubMed]  
		 
		
			
				2. 
			
				Das, R. K., Banerjee, S. and Bhattacharya, S.  Amelioration of benzo (a) pyrene-induced lung carcinogenesis in strain A mice by diphenylmethyl selenocyanate. Experimental and Toxicologic Pathology.  2007.  58, 351-360. [PubMed]  
		 
		
			
				3. 
			
				Sengupta, A., Ghosh, S., Das, R. K. , Bhattacharjee, S. and Bhattacharya, S.  Chemopreventive potential of diallylsulfide, lycopene and theaflavin during chemically induced colon carcinogenesis in rat colon through modulation of cyclooxygenase-2 and inducible nitric oxide synthase pathways. European Journal of Cancer Prevention.  2006.  15, 301-305. [PubMed]  
		 
		
			
				4. 
			
				Das, R. K. , Hossain, S. K. and Bhattacharya, S.  Diphenylmethyl selenocyanate inhibits DMBA-croton oil induced two-stage mouse skin carcinogenesis by inducing apoptosis and inhibiting cutaneous cell proliferation. Cancer Letters.  2005.  230, 90-101. [PubMed]  
		 
		
			
				5. 
			
				Das, R. K. , Das, S. and Bhattacharya, S.  Protective effect of diphenylmethyl selenocyanate against carbon tetrachloride-induced hepatotoxicity in vivo. Journal of Environmental Pathology, Toxicology and Oncology.  2004.  23, 287-296. [PubMed]  
		 
		
			
				6. 
			
				Das, R. K. , Ghosh, S., Sengupta, A., Das, S. and Bhattacharya, S.  Inhibition of DMBA/croton oil-induced two-stage mouse skin carcinogenesis by diphenylmethyl selenocyanate. European Journal of Cancer Prevention.  2004.  13, 411-417. [PubMed]  
		 
		
			
				7. 
			
				Ghosh, S., Das, R. K. , Sengupta, A. & Bhattacharya, S. (2005). Induction of apoptosis and inhibition of cell proliferation by Diphenylmethyl selenocyanate during azoxymethane induced rat colon carcinogenesis. 2005. International Journal of Cancer Prevention .2, 63-70. 
		 
		
			
				8. 
			
				Ghosh, S., Das, R. K. , Sengupta, A. & Bhattacharya, S. Inhibition of azoxymethane-induced aberrant crypt foci in rat by Diphenylmethyl selenocyanate through downregulation of COX-2 and modulation of glutathione-S-transferase and lipid peroxidation. Biological Trace Element Research.  2005. 105, 171-186. 
		 
	 
	 
  
                           
                         
                                                
 
                      
                          
                            
                               
                             
                            
                                
                             
                            
                              
                                  
                                     
                                   
                                  
                                                                            
                                        
                                                                                    
                                            Education  
 
                                           
                                                                                    
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                                            M.Sc.                                                    				
				 
                                                                                                                            
 
                                           
                                                                                    
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                                            Ph.D.                                                    				
				 
                                                                                                                            
 
                                           
                                                                                  
                                       
                                       
                                   
                              
 
                             
                          
                        
                            
                               
                             
                            
                                                                
                                  
                                    
                                      Type of Neoplasms 
 
                                     
                                                                                                            
                                      Pulmonary system 
 
                                     
									                                    
                                      
                                          Lung