INCREDB ID : 204
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Gayatri Ramakrishna, Ph.D.
Head 
 
Centre for DNA Fingerprinting and Diagnostics
Cancer Biology Lab
Bldg. 7, Gruhakalpa, 5-4-399 / B, Nampally
Hyderabad - 500 001   
Andhra Pradesh   
 
E-mail: gayatri@cdfd.org.in
Phone: +91-40-24749414
Fax: +91-40-24749448
 
URL: http://cdfd.org.in/labpages/gayatri_ramakrishna.html
 
Positions Held:
Position Affiliation Time Period
Post Doctoral Fellowship National Cancer Institute, National Institutes of Health, MD, USA
 
Area of Specialization:
Molecular Biology
Cancer Biology
Research Summary:
Role of K-RAS in Lung Tumorigenesis
Human Papilloma Virus (HPV) Screening in the Cervical Scrapes from Rural Andhra Pradesh
 
Publications:
1. Bose, S., Sakhuja, P., Bezawada, L., Agarwal, A. K., Kazim, S. N., Khan, L. A., Sarin, S. K. and Ramakrishna, G.  Hepatocellular carcinoma with persistent hepatitis B virus infection shows unusual downregulation of Ras expression and differential response to Ras mediated signaling. Journal of Gastroenterology and Hepatology. 2011.  26, 135-144. [PubMed]
2. Sowjanya, A. P., Paul, P., Vedantham, H., Ramakrishna, G., Vidyadhari, D., Vijayaraghavan, K., Laksmi, S., Sudula, M., Ronnett, B. M., Das, M., Shah, K. V. and Gravitt, P. E.  Suitability of self-collected vaginal samples for cervical cancer screening in periurban villages in Andhra Pradesh, India. Cancer Epidemiology, Biomarkers & Prevention. 2009.  18, 1373-1378. [PubMed]
3. Gokul, G., Gautami, B., Malathi, S., Sowjanya, A. P., Poli, U. R., Jain, M., Ramakrishna, G. and Khosla, S.  DNA methylation profile at the DNMT3L promoter: a potential biomarker for cervical cancer. Epigenetics : Official Journal of the DNA Methylation Society. 2007.  2, 80-85. [PubMed]
4. Gokul, G., Ramakrishna, G. and Khosla, S.  Reprogramming of HeLa cells upon DNMT3L overexpression mimics carcinogenesis. Epigenetics . 2009.  4, 322-329. [PubMed]
5. Vucenik, I., Ramakrishna, G., Tantivejkul, K., Anderson, L. M. and Ramljak, D.  Inositol hexaphosphate (IP6) blocks proliferation of human breast cancer cells through a PKCdelta-dependent increase in p27Kip1 and decrease in retinoblastoma protein (pRb) phosphorylation. Breast Cancer Research and Treatment. 2005.  91, 35-45. [PubMed]
6. Padma, S., Sowjanya, A. P., Poli, U. R., Jain, M., Rao, B. and Ramakrishna, G.  Downregulation of calcineurin activity in cervical carcinoma. Cancer Cell International. 2005.  5, 7. [PubMed]
7. Singh, A., Sowjanya, A. P. and Ramakrishna, G.  The wild-type Ras: road ahead. The FASEB Journal . 2005.  19, 161-169. [PubMed]
8. Gayatri, R. and Chatterjee, S.  Effects of chlorpromazine on growth and development of Dictyostelium discoideum. Microbios. 1991.  68, 97-107. [PubMed]
9. Gayatri, R. and Chatterjee, S.  Effects of lindane on growth of cellular slime mold Dictyostelium discoideum. Bulletin of Environmental Contamination and Toxicology. 1992.  49, 285-289. [PubMed]
10. Gayatri, R. and Chatterjee, S.  Phosphatase activities in pesticide-treated growing and developing cells of Dictyostelium discoideum. Journal of Applied Toxicology : JAT. 1993.  13, 297-300. [PubMed]
11. Gayatri, R. and Chatterjee, S.  Phagocytic activity of Dictyostelium amoebae treated with an organochlorine pesticide. Cell Biology International. 1993.  17, 349-352. [PubMed]
12. Gayatri, R. and Chatterjee, S.  Pinocytic stimulation in Dictyostelium discoideum by gamma-benzene hexachloride. Journal of Cellular Physiology. 1994.  158, 523-526. [PubMed]
13. Gayatri, R. and Chatterjee, S.  Growth and development of cellular slime mould Dictyostelium discoideum treated with DDT. Environmental Pollution. 1994.  86, 135-140. [PubMed]
14. Sithanandam, G., Ramakrishna, G., Diwan, B. A. and Anderson, L. M.  Selective mutation of K-ras by N-ethylnitrosourea shifts from codon 12 to codon 61 during fetal mouse lung maturation. Oncogene. 1998.  17, 493-502. [PubMed]
15. Rice, P. L., Porter, S. E., Koski, K. M., Ramakrishna, G., Chen, A., Schrump, D., Kazlauskas, A. and Malkinson, A. M.  Reduced receptor expression for platelet-derived growth factor and epidermal growth factor in dividing mouse lung epithelial cells. Molecular Carcinogenesis. 1999.  25, 285-294. [PubMed]
16. Ramakrishna, G., Bialkowska, A., Perella, C., Birely, L., Fornwald, L. W., Diwan, B. A., Shiao, Y. H. and Anderson, L. M.  Ki-ras and the characteristics of mouse lung tumors. Molecular Carcinogenesis. 2000.  28, 156-167. [PubMed]
17. Diwan, B. A., Ramakrishna, G., Anderson, L. M. and Ramljak, D.  Overexpression of Grb2 in inflammatory lesions and preneoplastic foci and tumors induced by N-nitrosodimethylamine in Helicobacter hepaticus-infected and -noninfected A/J mice. Toxicologic Pathology. 2000.  28, 548-554. [PubMed]
18. Shiao, Y. H., Resau, J. H., Nagashima, K., Anderson, L. M. and Ramakrishna, G.  The von Hippel-Lindau tumor suppressor targets to mitochondria. Cancer Research. 2000.  60, 2816-2819. [PubMed]
19. Ramakrishna, G., Sithanandam, G., Cheng, R. Y., Fornwald, L. W., Smith, G. T., Diwan, B. A. and Anderson, L. M.  K-ras p21 expression and activity in lung and lung tumors. Experimental Lung Research. 2000.  26, 659-671. [PubMed]
20. McKenna, I. M., Ramakrishna, G., Diwan, B. A., Kang, Y., Shiao, Y. H., Wakefield, L. M., Powell, D. A., Anderson, L. M. and Jakowlew, S. B.  Heterozygous inactivation of TGF-beta1 increases the susceptibility to chemically induced mouse lung tumorigenesis independently of mutational activation of K-ras. Toxicology Letters. 2001.  123, 151-158. [PubMed]
21. Rama, Devi, A., R., Govindiah, V., Ramakrishna, G. and Naushad, S., M., Prevalence of Methylene tetrahydrofolate reductase polymorphism in South Indian population. Current Science, 86(3) 440-443.
22. Ramakrishna, G. and Chatterjee, S.: Morphogenesis of Dictyostelium discoideum cells exposed to organochlorine pesticide.  Bulletin of Environmental Contamination and Toxicology,1994, 52:  871-877.
23. Ramakrishna, G. and Anderson, L., M., : Levels and membrane localization of the c-K-ras p21 protein in lungs of mice of different genetic strains and effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and Aroclor 1254. Carcinogenesis, 1998, 19:  463-470.
24. Ramakrishna, G., Sithanadam G, Fornwald L. Smith G T and Anderson L M. GTP loading of K-ras p21 in mouse lung type 2 cells is dependent on cell density and anchorage. (submitted)
25. Shiao, Y., H., Ramakrishna, G., Anderson, L., M., Perantoni, A., O., Rice, J., M. and Diwan, B., A., :  Down-regulation of Von Hippel-Lindau protein in nitroso compound-induced rat non-clear cell kidney tumors. (submitted)

 
 
Education 
::
Ph.D. in Biochemistry, Jawaharlal Nehru University, New Delhi, India
  Last modified on : Mar 4, 2011
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